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    METHODS OF ABLATING TISSUE USING A CATHETER INJECTION SYSTEM
    42.
    发明申请
    METHODS OF ABLATING TISSUE USING A CATHETER INJECTION SYSTEM 有权

    公开(公告)号：US20210290302A1

    公开(公告)日：2021-09-23

    申请号：US17232560

    申请日：2021-04-16

    Applicant: Ablative Solutions, Inc.

    Inventor： David R. Fischell ,  Tim A. Fischell

    IPC: A61B18/14 ,  A61M5/00

    Abstract: At the present time, physicians often treat patients with atrial fibrillation (AF) using radiofrequency (RF) catheter systems to ablate conducting tissue in the wall of the Left Atrium of the heart around the ostium of the pulmonary veins. These systems are expensive and take time consuming to use. The present invention circular ablation system CAS includes a multiplicity of expandable needles that can be expanded around a central axis and positioned to inject a fluid like ethanol to ablate conductive tissue in a ring around the ostium of a pulmonary vein quickly and without the need for expensive capital equipment. The expansion of the needles is accomplished by self-expanding or balloon expandable structures. The invention includes centering means so that the needles will be situated in a pattern surrounding the outside of the ostium of a vein. Also included are members that limit the distance of penetration of the needles into the wall of the left atrium. The present invention also has application to ablating tissue around the ostium of a renal artery for the treatment of hypertension.

    PERI-VASCULAR TISSUE ABLATION CATHETERS
    43.
    发明申请
    PERI-VASCULAR TISSUE ABLATION CATHETERS 有权

    公开(公告)号：US20210205011A1

    公开(公告)日：2021-07-08

    申请号：US17127151

    申请日：2020-12-18

    Applicant: Ablative Solutions, Inc.

    Inventor： David R. Fischell ,  Tim A. Fischell ,  Robert Ryan Ragland ,  Darrin James Kent ,  Andy Edward Denison ,  Eric Thomas Johnson ,  Jeff Alan Burke ,  Christopher Scott Hayden

    IPC: A61B18/14 ,  A61B17/34 ,  A61M25/00 ,  A61B90/00 ,  A61B18/04

    Abstract: An intravascular catheter for peri-vascular and/or peri-urethral tissue ablation includes multiple needles advanced through supported guide tubes which expand around a central axis to engage the interior surface of the wall of the renal artery or other vessel of a human body allowing the injection an ablative fluid for ablating tissue, and/or nerve fibers in the outer layer or deep to the outer layer of the vessel, or in prostatic tissue. The system may also include a means to limit and/or adjust the depth of penetration of the ablative fluid into and beyond the tissue of the vessel wall. The catheter may also include structures which provide radial and/or lateral support to the guide tubes so that the guide tubes expand uniformly and maintain their position against the interior surface of the vessel wall as the sharpened injection needles are advanced to penetrate into the vessel wall. A method can involve injection/infusion of the ablative fluid over an extended time period of at least 10 seconds or with two injections at two different penetration depths to reduce or eliminate patient pain during ablation.

    PERI-VASCULAR TISSUE ABLATION CATHETERS
    47.
    发明申请
    PERI-VASCULAR TISSUE ABLATION CATHETERS 审中-公开

    公开(公告)号：US20190076188A1

    公开(公告)日：2019-03-14

    申请号：US15947626

    申请日：2018-04-06

    Applicant: Ablative Solutions, Inc.

    Inventor： David R. Fischell ,  Tim A. Fischell ,  Robert Ryan Ragland ,  Darrin James Kent ,  Andy Edward Denison ,  Eric Thomas Johnson ,  Jeff Alan Burke ,  Christopher Scott Hayden

    IPC: A61B18/14 ,  A61B90/00 ,  A61B17/34

    Abstract: An intravascular catheter for peri-vascular and/or peri-urethral tissue ablation includes multiple needles advanced through supported guide tubes which expand around a central axis to engage the interior surface of the wall of the renal artery or other vessel of a human body allowing the injection an ablative fluid for ablating tissue, and/or nerve fibers in the outer layer or deep to the outer layer of the vessel, or in prostatic tissue. The system may also include a means to limit and/or adjust the depth of penetration of the ablative fluid into and beyond the tissue of the vessel wall. The catheter may also include structures which provide radial and/or lateral support to the guide tubes so that the guide tubes expand uniformly and maintain their position against the interior surface of the vessel wall as the sharpened injection needles are advanced to penetrate into the vessel wall. A method can involve injection/infusion of the ablative fluid over an extended time period of at least 10 seconds or with two injections at two different penetration depths to reduce or eliminate patient pain during ablation.

    PERI-VASCULAR TISSUE ABLATION CATHETERS
    48.
    发明申请
    PERI-VASCULAR TISSUE ABLATION CATHETERS 审中-公开

    公开(公告)号：US20190076187A1

    公开(公告)日：2019-03-14

    申请号：US15947619

    申请日：2018-04-06

    Applicant: Ablative Solutions, Inc.

    Inventor： David R. Fischell ,  Tim A. Fischell ,  Robert Ryan Ragland ,  Darrin James Kent ,  Andy Edward Denison ,  Eric Thomas Johnson ,  Jeff Alan Burke ,  Christopher Scott Hayden

    IPC: A61B18/14 ,  A61B90/00 ,  A61B17/34

    Abstract: An intravascular catheter for peri-vascular and/or peri-urethral tissue ablation includes multiple needles advanced through supported guide tubes which expand around a central axis to engage the interior surface of the wall of the renal artery or other vessel of a human body allowing the injection an ablative fluid for ablating tissue, and/or nerve fibers in the outer layer or deep to the outer layer of the vessel, or in prostatic tissue. The system may also include a means to limit and/or adjust the depth of penetration of the ablative fluid into and beyond the tissue of the vessel wall. The catheter may also include structures which provide radial and/or lateral support to the guide tubes so that the guide tubes expand uniformly and maintain their position against the interior surface of the vessel wall as the sharpened injection needles are advanced to penetrate into the vessel wall. A method can involve injection/infusion of the ablative fluid over an extended time period of at least 10 seconds or with two injections at two different penetration depths to reduce or eliminate patient pain during ablation.

    PERI-VASCULAR TISSUE ABLATION CATHETERS
    49.
    发明申请
    PERI-VASCULAR TISSUE ABLATION CATHETERS 审中-公开

    公开(公告)号：US20190076186A1

    公开(公告)日：2019-03-14

    申请号：US15947618

    申请日：2018-04-06

    Applicant: Ablative Solutions, Inc.

    Inventor： David R. Fischell ,  Tim A. Fischell ,  Robert Ryan Ragland ,  Darrin James Kent ,  Andy Edward Denison ,  Eric Thomas Johnson ,  Jeff Alan Burke ,  Christopher Scott Hayden

    IPC: A61B18/14 ,  A61B90/00 ,  A61B17/34

    Abstract: An intravascular catheter for peri-vascular and/or peri-urethral tissue ablation includes multiple needles advanced through supported guide tubes which expand around a central axis to engage the interior surface of the wall of the renal artery or other vessel of a human body allowing the injection an ablative fluid for ablating tissue, and/or nerve fibers in the outer layer or deep to the outer layer of the vessel, or in prostatic tissue. The system may also include a means to limit and/or adjust the depth of penetration of the ablative fluid into and beyond the tissue of the vessel wall. The catheter may also include structures which provide radial and/or lateral support to the guide tubes so that the guide tubes expand uniformly and maintain their position against the interior surface of the vessel wall as the sharpened injection needles are advanced to penetrate into the vessel wall. A method can involve injection/infusion of the ablative fluid over an extended time period of at least 10 seconds or with two injections at two different penetration depths to reduce or eliminate patient pain during ablation.

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