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41.发明申请公开(公告)号：US20140276186A1
公开(公告)日：2014-09-18
申请号：US13862238
申请日：2013-04-12
Applicant: MEDTRONIC, INC.
Inventor： Scott R. Stanslaski , David L. Carlson , Peng Cong , Timothy J. Denison , David E. Linde , Randy M. Jensen
CPC classification number: A61B5/7225 , A61B5/04004 , A61B5/04012 , A61B5/0428 , A61B5/048 , A61B5/0496 , A61B5/7217 , A61N1/36125 , A61N1/3702 , A61N1/3704 , H03F3/38 , H03F2200/261
Abstract: This disclosure describes techniques for controlling spectral aggressors in a sensing device that uses a chopper amplifier to amplify an input signal prior to sampling the signal. In some examples, the techniques for controlling spectral aggressors may include generating a chopper-stabilized amplified version of an input signal based on a chopper frequency, sampling the chopper-stabilized amplified version of the input signal at a sampling rate to generate a sampled signal, and analyzing a target frequency band of the sampled signal. The chopper frequency and the sampling rate may cause spectral interference that is generated due to the chopper frequency to occur in the sampled signal at one or more frequencies that are outside of the target frequency band of the sampled signal. The techniques for controlling spectral aggressors may reduce the noise caused by the chopper frequency in the resulting sampled signal, thereby improving the quality of the signal.
Abstract translation: 本公开描述了用于控制感测装置中的光谱侵略者的技术，其在采样信号之前使用斩波放大器放大输入信号。 在一些示例中，用于控制频谱侵略者的技术可以包括基于斩波频率产生输入信号的斩波稳定放大版本，以采样率对输入信号的斩波稳定放大版本进行采样以产生采样信号， 并分析采样信号的目标频带。 斩波频率和采样率可能导致由于斩波频率在采样信号中在采样信号的目标频带之外的一个或多个频率处发生的频谱干扰。 用于控制频谱侵入者的技术可以减少由所得到的采样信号中的斩波频率引起的噪声，从而提高信号的质量。
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公开(公告)号：US20140135869A1
公开(公告)日：2014-05-15
申请号：US14161363
申请日：2014-01-22
Applicant: Medtronic, Inc.
Inventor： David L. Carlson , Randy M. Jensen , Timothy J. Denison , Jianping Wu , Gabriela C. Molnar , Scott R. Stanslaski , William J. Marks, JR.
IPC: A61N1/36
CPC classification number: A61N1/36067 , A61N1/0529 , A61N1/0534 , A61N1/36082 , A61N1/36185 , A61N1/37247
Abstract: Bioelectrical signals may be sensed within a brain of a patient with a plurality of sense electrode combinations. A stimulation electrode combination for delivering stimulation to the patient to manage a patient condition may be selected based on the frequency band characteristics of the sensed signals. In some examples, a stimulation electrode combination associated with the sense electrode combination that sensed a bioelectrical brain signal having a relatively highest relative beta band power level may be selected to deliver stimulation therapy to the patient. Other frequency bands characteristics may also be used to select the stimulation electrode combination.
Abstract translation: 可以在具有多个感测电极组合的患者的脑内感测生物电信号。 可以基于感测信号的频带特性来选择用于将刺激递送给患者以管理患者状况的刺激电极组合。 在一些示例中，可以选择与检测到具有相对较高的相对β带功率水平的生物电脑信号的感测电极组合相关联的刺激电极组合，以向患者传递刺激治疗。 也可以使用其他频带特性来选择刺激电极组合。
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公开(公告)号：US20130131755A1
公开(公告)日：2013-05-23
申请号：US13740860
申请日：2013-01-14
Applicant: Medtronic, Inc.
Inventor： Eric J. Panken , Timothy J. Denison , Gregory F. Molnar
IPC: A61N1/36
CPC classification number: A61N1/36139 , A61B5/048 , A61B5/4082 , A61B5/7475 , A61M5/14276 , A61M5/1723 , A61M2210/0693 , A61N1/36014 , A61N1/36017 , A61N1/36021 , A61N1/36025 , A61N1/3605 , A61N1/3606 , A61N1/36071 , A61N1/36082 , A61N1/37252 , G06F3/015
Abstract: A patient controls the delivery of therapy through volitional inputs that are detected by a biosignal within the brain. The volitional patient input may be directed towards performing a specific physical or mental activity, such as moving a muscle or performing a mathematical calculation. In one embodiment, a biosignal detection module monitors an electroencephalogram (EEG) signal from within the brain of the patient and determines whether the EEG signal includes the biosignal. In one embodiment, the biosignal detection module analyzes one or more frequency components of the EEG signal. In this manner, the patient may adjust therapy delivery by providing a volitional input that is detected by brain signals, wherein the volitional input may not require the interaction with another device, thereby eliminating the need for an external programmer to adjust therapy delivery. Example therapies include electrical stimulation, drug delivery, and delivery of sensory cues.
Abstract translation: 患者通过由大脑内的生物信号检测到的输入量来控制治疗的传递。 患者的输入可以指向执行特定的身体或精神活动，例如移动肌肉或执行数学计算。 在一个实施例中，生物信号检测模块监测来自患者脑内的脑电图（EEG）信号，并确定EEG信号是否包括生物信号。 在一个实施例中，生物信号检测模块分析EEG信号的一个或多个频率分量。 以这种方式，患者可以通过提供由脑信号检测到的输入量来调节治疗递送，其中，该输入可能不需要与另一个装置的相互作用，从而消除了外部程序员调整治疗递送的需要。 示例治疗包括电刺激，药物递送和感觉线索的递送。
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公开(公告)号：US11077305B2
公开(公告)日：2021-08-03
申请号：US15699873
申请日：2017-09-08
Applicant: MEDTRONIC, INC.
Inventor： Jonathon E. Giftakis , Timothy J. Denison , Paul H. Stypulkowski , Scott R. Stanslaski , Robert S. Raike , Mae Eng , David E. Linde , Thomas Adamski
Abstract: In some examples of selecting a target therapy delivery site for treating a patient condition, a relatively high frequency electrical stimulation signal is delivered to at least two areas within a first region (e.g., an anterior nucleus of the thalamus) of a brain of a patient, and changes in brain activity (e.g., as indicated by bioelectrical brain signals) within a second region (e.g., a hippocampus) of the brain of the patient in response to the delivered stimulation are determined. The target therapy delivery site, an electrode combination, or both, may be selected based on the changes in brain activity.
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公开(公告)号：US10953222B2
公开(公告)日：2021-03-23
申请号：US15714888
申请日：2017-09-25
Applicant: Medtronic, Inc.
Inventor： Scott R. Stanslaski , Timothy R. Abraham , Thomas Adamski , Timothy J. Denison , Robert S. Raike , Christopher Pulliam
Abstract: Techniques are disclosed for delivering electrical stimulation therapy to a patient. In one example, a medical system delivers electrical stimulation therapy to a tissue of the patient via electrodes. The medical system determines a first response of a first sensed signal of the patient to the electrical stimulation therapy and a second response of a second sensed signal of the patient to the electrical stimulation therapy. Based on the first response and the second response for controlling the electrical stimulation therapy, the medical system selects one of the first sensed signal and the second sensed signal of the patient. The medical system adjusts a level of at least one parameter of the electrical stimulation therapy based on the selected one of the first sensed signal and the second sensed signal.
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Patent Agency Ranking
公开(公告)号：US20210052890A1
公开(公告)日：2021-02-25
申请号：US16949583
申请日：2020-11-04
Applicant: Medtronic, Inc.
Inventor： Xuan K. Wei , Linnea Burman , Timothy J. Denison , Nnamdi Njoku , Maren Bean
Abstract: Systems, devices, and techniques are disclosed for predicting a urinary event of a patient. In one example, a system comprises a fluid consumption cup comprising one or more sensors. The system may comprise communication circuitry configured to receive, from the fluid consumption cup, one or more signals that indicate an amount of fluid removed from the fluid consumption cup. The system may comprise processing circuitry configured to: update a patient log based on the one or more signals that indicate the amount of fluid removed from the fluid consumption cup; determine that the urinary event is predicted to occur, the occurrence of the urinary event predicted based on the patient log; and provide, in response to the determination and for receipt by the patient, a notification that the urinary event is predicted to occur.
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公开(公告)号：US10856792B2
公开(公告)日：2020-12-08
申请号：US15902606
申请日：2018-02-22
Applicant: Medtronic, Inc.
Inventor： Xuan K. Wei , Linnea Burman , Timothy J. Denison , Nnamdi Njoku , Maren Bean
IPC: A61B5/00 , A61B5/20 , A61B5/145 , G16H10/40 , G16H50/20 , G16H10/60 , G16H40/63 , G16H40/67 , G16B40/00
Abstract: Systems, devices, and techniques are disclosed for predicting a urinary event of a patient. In one example, a system comprises a fluid consumption cup comprising one or more sensors. The system may comprise communication circuitry configured to receive, from the fluid consumption cup, one or more signals that indicate an amount of fluid removed from the fluid consumption cup. The system may comprise processing circuitry configured to: update a patient log based on the one or more signals that indicate the amount of fluid removed from the fluid consumption cup; determine that the urinary event is predicted to occur, the occurrence of the urinary event predicted based on the patient log; and provide, in response to the determination and for receipt by the patient, a notification that the urinary event is predicted to occur.
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公开(公告)号：US20200376258A1
公开(公告)日：2020-12-03
申请号：US16947949
申请日：2020-08-25
Applicant: Medtronic, Inc.
Inventor： Erik R. Scott , John E. Kast , Xuan K. Wei , Todd V. Smith , Joel A. Anderson , Forrest C. M. Pape , Duane L. Bourget , Timothy J. Denison , David A. Dinsmoor , Randy S. Roles , Stephen J. Roddy
Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.
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公开(公告)号：US10406281B2
公开(公告)日：2019-09-10
申请号：US15681957
申请日：2017-08-21
Applicant: Medtronic, Inc.
Inventor： Keith A. Miesel , James M. Haase , Chris J. Paidosh , Darren A. Janzig , Timothy J. Denison
Abstract: The disclosure is directed to a pressure sensor of an implantable medical device. The pressure sensor may utilize detect fluid pressure based on a changing capacitance between two capacitive elements. The pressure sensor may define at least a portion of a fluid enclosure of the IMD. In one example, the pressure sensor has a self-aligning housing shape that occludes an opening in the pump bulkhead of the IMD. An operative surface of the pressure and the portion of the fluid enclosure may be formed of a corrosion resistant and/or biocompatible material. A first capacitive element of the pressure sensor may be a metal alloy diaphragm that deflects in response to external fluid pressure. A second capacitive element of the pressure sensor may be a metal coating on a rigid insulator sealed from the fluid by the diaphragm and a housing of the sensor.
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公开(公告)号：US10045764B2
公开(公告)日：2018-08-14
申请号：US15793636
申请日：2017-10-25
Applicant: Medtronic, Inc.
Inventor： Erik R. Scott , John E. Kast , Xuan K. Wei , Todd V. Smith , Joel A. Anderson , Forrest C. M. Pape , Duane L. Bourget , Timothy J. Denison , David A. Dinsmoor , Randy S. Roles , Stephen J. Roddy
Abstract: An external medical device generates a drive signal inductively coupled to an implantable coil from an external coil. A regulator module coupled to the implantable coil generates an output signal in response to the inductively coupled signal and a feedback signal correlated to an amplitude of the inductively coupled signal. A signal generator receives the output signal for generating a therapeutic electrical stimulation signal. The control module adjusts the drive signal in response to the feedback signal to control the electrical stimulation signal.
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