公开(公告)号：US20110203581A1

公开(公告)日：2011-08-25

申请号：US13013070

申请日：2011-01-25

Applicant: Jenni Rimbaugh ,  Lauri J. DeVore

Inventor： Jenni Rimbaugh ,  Lauri J. DeVore

IPC: A61M16/00

CPC classification number: A61M29/02 ,  A61B17/12022 ,  A61B17/12104 ,  A61B17/12172 ,  A61B17/24 ,  A61B2017/1205 ,  A61B2017/242 ,  A61B2090/037 ,  A61F2002/043 ,  A61M2029/025

Abstract: An apparatus and method deploy a self-expandable bronchial obstruction device in an air passageway. The apparatus includes a catheter configured to be passed down the trachea. The apparatus further includes a capsule for housing the self-expandable bronchial obstruction device in a sterile environment. The capsule is configured to be advanced down the catheter. The capsule further includes a tubular extension. The capsule has a breakable seam so as to release the bronchial obstruction device in the air passageway upon a proximal force being exerted upon the bronchial obstruction device. The method includes guiding a conduit down a trachea into the air passageway. The method further includes advancing a capsule having a bronchial device therein down an internal lumen of the conduit into the air passageway. The method further includes releasing the bronchial device from the capsule. The method further includes deploying the bronchial device into the air passageway.

Abstract translation: 一种在空气通道中部署自发性支气管阻塞装置的装置和方法。 该装置包括配置成沿气管传下来的导管。 该装置还包括用于在无菌环境中容纳自发性支气管阻塞装置的胶囊。 胶囊构造成在导管上向下推进。 胶囊还包括管状延伸部。 胶囊具有可断裂的接缝，以便当近端力施加在支气管阻塞装置上时，释放气道中的支气管阻塞装置。 该方法包括将气管引导到空气通道中。 该方法还包括将具有支气管装置的胶囊向下推入导管的内腔进入空气通道。 该方法还包括从胶囊释放支气管装置。 该方法还包括将支气管装置部署到空气通道中。

公开(公告)号：US20110196295A1

公开(公告)日：2011-08-11

申请号：US13073443

申请日：2011-03-28

Applicant: Hugo X. Gonzalez ,  Steven Chase Springmeyer ,  Richard O. Shea ,  John H. Wang ,  Lauri J. DeVore

Inventor： Hugo X. Gonzalez ,  Steven Chase Springmeyer ,  Richard O. Shea ,  John H. Wang ,  Lauri J. DeVore

IPC: A61M31/00

CPC classification number: A61M31/002 ,  A61B17/12022 ,  A61B17/12036 ,  A61B17/1204 ,  A61B17/12104 ,  A61B17/12159 ,  A61B17/12172 ,  A61B2017/1205 ,  A61B2017/22051 ,  A61B2017/22067 ,  A61B2017/242 ,  A61B2217/005 ,  A61F2002/043 ,  A61M1/0023 ,  A61M25/04 ,  A61M31/00 ,  A61M2025/0076 ,  A61M2210/1035 ,  A61N5/1027 ,  A61N2005/1021

Abstract: The present invention includes an intra-bronchial device, system, and method for providing a therapeutic agent to a patient. A device includes a flow control member for placement in an air passageway communicating with a lung portion and when deployed in the air passageway inhibits a therapeutic agent distal of the control member from moving proximal of the control member, and includes the therapeutic agent associated with the flow control member. The control member may inhibit movement of the therapeutic agent by limiting airflow, and may include a one-way valve limiting exhalation of air from the lung portion. The control member may include a flexible membrane impervious to air flow, or a separator arranged to inhibit the movement of the therapeutic agent. The control member may include at least one anchor, and the anchor may be releasable from the air passageway for removal of the intra-bronchial device.

Abstract translation: 本发明包括用于向患者提供治疗剂的支气管内装置，系统和方法。 一种装置包括用于放置在与肺部连通的空气通道中的流量控制构件，并且当部署在空气通道中时，阻止控制构件远端的治疗剂移动到控制构件的近侧，并且包括与 流量控制构件。 控制构件可以通过限制气流来抑制治疗剂的移动，并且可以包括限制从肺部呼出空气的单向阀。 控制构件可以包括不透气体的柔性膜，或者设置成抑制治疗剂运动的隔膜。 控制构件可以包括至少一个锚固件，并且锚固件可以从空气通道释放以去除支气管内装置。

公开(公告)号：US07854228B2

公开(公告)日：2010-12-21

申请号：US11092123

申请日：2005-03-28

Applicant: Peter M. Wilson ,  Antony J. Fields ,  Hanson S. Gifford, III ,  John G. McCutcheon ,  Michael J. Hendricksen ,  Alan R. Rapacki ,  David R. Tholfsen ,  Michael S. Barrett ,  Ronald Hundertmark ,  Douglas Sutton

Inventor： Peter M. Wilson ,  Antony J. Fields ,  Hanson S. Gifford, III ,  John G. McCutcheon ,  Michael J. Hendricksen ,  Alan R. Rapacki ,  David R. Tholfsen ,  Michael S. Barrett ,  Ronald Hundertmark ,  Douglas Sutton

IPC: A61M15/00 ,  A61M16/00 ,  A62B18/08 ,  A62B18/10 ,  A61C5/14 ,  A61F2/20 ,  A61B5/08

CPC classification number: A61F2/2412 ,  A61B2017/1205 ,  A61F2/04 ,  A61F2/06 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/91 ,  A61F2002/043 ,  A61F2002/9522 ,  Y10S128/912

Abstract: Methods and systems for lung volume reduction of a patient are described. The methods include implanting a flow control device in a bronchial passageway of the lung. The flow control device regulates fluid flow through the bronchial passageway and includes a valve protector that at least partially surrounds a valve member. The valve protector has sufficient rigidity to maintain the shape of the valve member against compression.

Abstract translation: 描述了患者肺容积减少的方法和系统。 所述方法包括在肺的支气管通道中植入流量控制装置。 流量控制装置调节通过支气管通道的流体流动并且包括至少部分地围绕阀构件的阀保护器。 阀保护器具有足够的刚性以保持阀构件的形状不被压缩。

公开(公告)号：US07842061B2

公开(公告)日：2010-11-30

申请号：US10746981

申请日：2003-12-23

Applicant: David H. Dillard ,  Hugo X. Gonzalez ,  Seung Yi ,  Lauri J. DeVore ,  Mia Park ,  Dean T. Corcoran ,  Jenni Rimbaugh

Inventor： David H. Dillard ,  Hugo X. Gonzalez ,  Seung Yi ,  Lauri J. DeVore ,  Mia Park ,  Dean T. Corcoran ,  Jenni Rimbaugh

IPC: A61M29/00

CPC classification number: A61B17/12104 ,  A61B17/12172 ,  A61B2017/00809 ,  A61F2/24 ,  A61F2002/043

Abstract: An intra-bronchial device placed and anchored in an air passageway of a patient to collapse a lung portion associated with the air passageway. The device includes a support structure, an obstructing member carried by the support structure that reduces ventilation to the lung portion by preventing air from being inhaled into the lung portion, and at least one anchor carried by the support structure that anchors the obstruction device within the air passageway. The anchor may engage the air passageway wall by piercing or friction, include a stop dimensioned for limiting the piercing of the air passageway wall, and may be releasable from the air passageway for removal of the intra-bronchial device. The anchors may be carried by a peripheral portion of the support structure, or by a central portion of the support structure. The obstructing member may be a one-way valve.

Abstract translation: 将支气管内装置放置并锚定在患者的空气通道中以折叠与空气通道相关联的肺部分。 该装置包括支撑结构，由支撑结构承载的阻塞构件，其通过防止空气被吸入肺部而减少对肺部的通气，以及由支撑结构承载的至少一个锚固件，其将阻塞装置固定在内部 空气通道。 锚固件可以通过穿孔或摩擦接合空气通道壁，包括尺寸适于限制空气通道壁的刺穿的止挡件，并且可以从空气通道释放以去除支气管内装置。 锚固件可以由支撑结构的周边部分或支撑结构的中心部分承载。 阻塞构件可以是单向阀。

公开(公告)号：US07670373B1

公开(公告)日：2010-03-02

申请号：US09762692

申请日：1998-03-03

Applicant: Sabaratnam Sabanathan ,  Thirumani Sabanathan, legal representative

Inventor： Sabaratnam Sabanathan

IPC: A61F2/20 ,  A61M16/00

CPC classification number: A61B17/12172 ,  A61B17/12022 ,  A61B17/12104 ,  A61B17/12136 ,  A61B17/12159 ,  A61B17/12177 ,  A61B2017/1205 ,  A61F2002/043

Abstract: An obturator for a bronchial tube or tubule of a human or animal lung comprises a blocking element (92) and a securing element (90). The blocking element serves to seal the tube or tubule against the passage of fluid past the obturator when the obturator is disposed in a bronchial tube or tubule. The securing element serves to retain the blocking element in position. The blocking element comprises a substantially cylindrical plug of biocompatible, resiliently deformable closed-cell foamed plastics material, such as PVC. The securing element comprises a stent having barbs (98) to engage and retain the blocking element. The stent also has anchors (100) to retain the stent in a bronchial tube or tubule. A method of treatment of emphysema or other lung conditions or diseases in human or animal patients comprises placing an obturator in a bronchial tube or tubule of the patient so as to seal the tube or tubule against the passage of fluid past the obturator.

Abstract translation: 用于人或动物肺的支气管或小管的闭孔器包括阻挡元件（92）和固定元件（90）。 当闭塞器设置在支气管或小管中时，阻塞元件用于密封管或小管抵抗流体经过闭孔器的通道。 固定元件用于将阻挡元件保持在适当的位置。 阻挡元件包括生物相容的，可弹性变形的闭孔发泡塑料材料（例如PVC）的基本上圆柱形的塞子。 固定元件包括具有倒钩（98）以使接合和保持阻挡元件的支架。 支架还具有将支架保持在支气管或小管中的锚固件（100）。 治疗人或动物患者的肺气肿或其他肺病或疾病的方法包括将填塞物放置在患者的支气管或小管中，以密封管或小管以防止流体通过闭孔器。

公开(公告)号：US20090255537A1

公开(公告)日：2009-10-15

申请号：US12490625

申请日：2009-06-24

Applicant: David Peter Shaw ,  John McCutcheon ,  Antony J. Fields

Inventor： David Peter Shaw ,  John McCutcheon ,  Antony J. Fields

IPC: A62B9/02 ,  A61M31/00

CPC classification number: A61F2/04 ,  A61B17/12036 ,  A61B17/12104 ,  A61B17/12159 ,  A61B17/12172 ,  A61F2/24 ,  A61F2/82 ,  A61F2002/043

Abstract: Disclosed are various disease indications and treatment methods that benefit from selective lung region isolation. A lung region is bronchially isolated by regulating the flow of fluid to and from the lung region, such as by implanting one or more bronchial isolation devices into one or more bronchial passageways that feed air to the lung region. The bronchial isolation devices can comprise, for example, one-way valves, two-way valves, occluders or blockers, ligating clips, glues, sealants, and sclerosing agents.

Abstract translation: 公开了从选择性肺区域分离中受益的各种疾病适应症和治疗方法。 通过调节流入和流出肺部区域的流体的流动，例如通过将一个或多个支气管隔离装置植入一个或多个向肺部区域进食空气的支气管通道，肺部区域被支气管分离。 支气管隔离装置可以包括例如单向阀，双向阀，闭塞器或阻塞器，结扎夹，胶水，密封剂和硬化剂。

公开(公告)号：US07533671B2

公开(公告)日：2009-05-19

申请号：US10745401

申请日：2003-12-22

Applicant: Hugo Xavier Gonzalez ,  Steven C Springmeyer ,  William A. Sirokman

Inventor： Hugo Xavier Gonzalez ,  Steven C Springmeyer ,  William A. Sirokman

IPC: A62B18/10

CPC classification number: A61B17/12104 ,  A61B17/12022 ,  A61B17/12136 ,  A61B17/12172 ,  A61B2017/00809 ,  A61B2017/12054 ,  A61F2002/043

Abstract: Methods and systems for minimally invasively treating an air leak in a lung comprise the steps of detecting an air leak in a lung; locating an airway in fluid communication with the air leak, introducing a bronchoscope into a patient's airway to a position adjacent the target section and occluding an airway upstream of the air leak for a period of time. The airway occlusion is preferably removed after the air leak has substantially permanently healed. The method can also include the injection of a substance into the airway on a distal side of the occlusion.

Abstract translation: 用于微创侵入性处理肺部空气泄漏的方法和系统包括检测肺中的空气泄漏的步骤; 定位与空气泄漏流体连通的气道，将支气管镜引入患者的气道中至与目标部分相邻的位置，并在空气泄漏上游封闭气道一段时间。 空气泄漏基本上永久愈合之后，优选除去气道闭塞。 该方法还可以包括在闭塞的远端侧将气体注入气道中。

公开(公告)号：US20090093668A1

公开(公告)日：2009-04-09

申请号：US11906917

申请日：2007-10-04

Applicant: Lewis H. Marten ,  Dennis F. Creedon

Inventor： Lewis H. Marten ,  Dennis F. Creedon

IPC: A61M36/12

CPC classification number: A61F2/04 ,  A61F2002/043 ,  A61F2002/046 ,  A61N5/1002

Abstract: This invention relates to a device for brachytherapy treatment of a tissue growth on the inner surface of an airway lumen. The invention also relates to a device for treatment of an obstructing tissue growth on the inner surface of an airway lumen. The device is comprised of a cylindrical tube having a proximal end, a distal end, and a continuous open cavity therebetween, wherein the device is deployed against the inner surface of the lumen. There is at least one longitudinal channel contained within the wall of the tube for positioning a treatment radiotherapy source in close proximity to said tissue growth. The present invention also discloses a method for treating a tissue growth on the inner surface of an airway lumen, and method for treating an obstructing tissue growth on the inner surface of an airway lumen

Abstract translation: 本发明涉及用于近距离放射治疗气道腔内表面上的组织生长的装置。 本发明还涉及一种用于治疗气道腔内表面上的阻塞性组织生长的装置。 该装置包括具有近端，远端和其间的连续开放腔的圆柱形管，其中该装置抵靠腔的内表面展开。 至少一个纵向通道包含在管的壁内，用于将处理放射治疗源定位成紧邻所述组织生长。 本发明还公开了一种用于治疗气道腔内表面上的组织生长的方法，以及用于治疗气道内腔表面上的阻塞性组织生长的方法

公开(公告)号：US07347814B2

公开(公告)日：2008-03-25

申请号：US11048278

申请日：2005-02-01

Applicant: Clifton A. Alferness ,  Robert Barry ,  Clint Finger ,  Hugo X. Gonzalez

Inventor： Clifton A. Alferness ,  Robert Barry ,  Clint Finger ,  Hugo X. Gonzalez

IPC: A61F2/00 ,  A61F13/00 ,  A61B17/08

CPC classification number: A61B17/12013 ,  A61B17/00234 ,  A61B50/36 ,  A61B2017/00526 ,  A61F2002/043

Abstract: A constriction device that constricts body tissue is viewable under X ray fluoroscopy. The device includes an elongated sleeve. The sleeve includes opposed opened ends and is formed from expandable or elastic material to receive therein, when in an expanded condition, body tissue to be constricted and to constrict the body tissue therein when released from the expanded condition. At least a portion of the sleeve includes X ray opaque material rendering the device visible under X ray fluoroscopy.

Abstract translation: 收缩身体组织的收缩装置可以在X射线透视下观察。 该装置包括细长套筒。 套筒包括相对的开口端，并且由可膨胀或弹性材料形成，以便当处于膨胀状态时，在从膨胀状态释放时收缩的身体组织被收缩并收缩身体组织。 套筒的至少一部分包括X射线不透明材料，使得该装置在X射线透视下可见。

公开(公告)号：US20070250162A1

公开(公告)日：2007-10-25

申请号：US11648908

申请日：2007-01-03

Applicant: John Royalty

Inventor： John Royalty

IPC: A61M1/10

CPC classification number: A61B5/0809 ,  A61F2002/043 ,  A61F2250/0001 ,  A61H31/02 ,  A61M2210/1014

Abstract: A diaphragm assist device includes a magnetic mat adapted for mounting inside a human body adjacent the diaphragm. The mat is made from a material responsive to application of an electromagnetic field so as to be movable into compressive relation with the diaphragm in response to application of the electromagnetic field thereto and movable out of the compressive relation to permit the diaphragm to relax when application of the electromagnetic field is discontinued. The device also includes an electromagnetic assembly adapted for surrounding the torso of the human body in functionally cooperative relation with respect to the mat, and for alternately generating and discontinuing the electromagnetic field so that the mat alternately moves into and out of the compressive relation with the diaphragm. The device also includes a controller constructed and arranged to control an intensity level of the electromagnetic field generated by the electromagnetic assembly.

Abstract translation: 隔膜辅助装置包括适于安装在邻近隔膜的人体内的磁性垫。 该垫由响应于施加电磁场的材料制成，以响应于向其施加电磁场而移动成与隔膜的压缩关系，并且可移出压缩关系，以允许隔膜在施加 电磁场停止。 该装置还包括电磁组件，其适于围绕人体的功能性协调关系围绕人体躯干，并且用于交替地产生和中断电磁场，使得垫交替地移动到和/ 隔膜 该装置还包括构造和布置成控制由电磁组件产生的电磁场的强度水平的控制器。