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    Drug delivery after biodegradation of the stent scaffolding
    53.
    发明授权
    Drug delivery after biodegradation of the stent scaffolding 有权
    支架支架生物降解后的药物输送

    公开(公告)号：US08016879B2

    公开(公告)日：2011-09-13

    申请号：US11823703

    申请日：2007-06-27

    Applicant: David C. Gale ,  Bin Huang

    Inventor： David C. Gale ,  Bin Huang

    IPC: A61F2/06

    CPC classification number: A61L31/14 ,  A61F2/82 ,  A61L31/146 ,  A61L31/148 ,  A61L31/16 ,  A61L2300/41 ,  A61L2300/416 ,  A61L2300/604

    Abstract: Disclosed is a stent comprising a bioabsorbable polymeric scaffolding; and a plurality of depots in at least a portion of the scaffolding, wherein the plurality of depots comprise a bioabsorbable material, wherein the degradation rate of all or substantially all of the bioabsorbable polymer of the scaffolding is faster than the degradation rate of all or substantially all of the bioabsorbable material of the depots.

    Abstract translation: 公开了一种支架，其包括生物可吸收聚合物支架; 以及在所述脚手架的至少一部分中的多个仓库，其中所述多个仓库包含生物可吸收材料，其中所述脚手架的所有或基本上全部所述生物可吸收聚合物的降解速度比全部或基本上 所有生物可吸收材料的仓库。

    Drug Delivery After Biodegradation Of The Stent Scaffolding
    54.
    发明申请
    Drug Delivery After Biodegradation Of The Stent Scaffolding 有权
    支架脚手架生物降解后的药物递送

    公开(公告)号：US20110190875A1

    公开(公告)日：2011-08-04

    申请号：US13086308

    申请日：2011-04-13

    Applicant: David C. Gale ,  Bin Huang

    Inventor： David C. Gale ,  Bin Huang

    IPC: A61F2/82

    CPC classification number: A61L31/10 ,  A61L31/148 ,  A61L31/16 ,  A61L2300/41 ,  A61L2300/416 ,  C08L67/04

    Abstract: Disclosed herein is a stent comprising: a bioabsorbable polymeric scaffolding; and a coating comprising a bioabsorbable material on at least a portion of the scaffolding, wherein the degradation rate of all or substantially all of the bioabsorbable polymer of the scaffolding is faster than the degradation rate of all or substantially all of the bioabsorbable material of the coating.

    Abstract translation: 本文公开了一种支架，其包括：生物可吸收聚合物支架; 以及在所述支架的至少一部分上包含生物可吸收材料的涂层，其中所述脚手架的全部或基本上全部所述生物可吸收聚合物的降解速度比所述涂层的所有或基本上全部所述生物可吸收材料的降解速度快 。

    DEVICES AND METHODS FOR DILATING TISSUES
    57.
    发明申请
    DEVICES AND METHODS FOR DILATING TISSUES 有权
    用于脱发组织的装置和方法

    公开(公告)号：US20100211093A1

    公开(公告)日：2010-08-19

    申请号：US12693336

    申请日：2010-01-25

    Applicant: Anthony J. Abbate ,  Gail M. Zaler ,  Richard E. Kaufman ,  David C. Gale ,  Bin Huang ,  Susan P. Stimson

    Inventor： Anthony J. Abbate ,  Gail M. Zaler ,  Richard E. Kaufman ,  David C. Gale ,  Bin Huang ,  Susan P. Stimson

    IPC: A61M29/00

    CPC classification number: A61M29/02 ,  A61B17/0206 ,  A61B17/0218 ,  A61B17/0293 ,  A61B17/3468 ,  A61M2205/04 ,  A61M2210/0618

    Abstract: Described here are devices and methods for dilating tissues. In other variations, the dilatation device comprises a slotted or expandable tube that may expand to dilate tissue. In still other variations, the dilatation device comprises two or more hinged or movable plate members that separate to dilate tissue. In yet other variations, the dilation device may comprise one or more flexible members. One or more portions of the dilatation device may be detachable from the device in the body, and dilatation device may release one or more implants into the body. In some of these variations, the dilatation device may additionally be used to expand one or more implants or other devices within the body. In some variations the dilatation device may release one or more substances that may hold dilated tissue in a dilated configuration.

    Abstract translation: 这里描述的是用于扩张组织的装置和方法。 在其它变型中，扩张装置包括可以膨胀以扩张组织的开槽或可扩张的管。 在另外的变型中，扩张装置包括两个或更多个铰接或可移动的板构件，其分开以扩张组织。 在另外的变型中，扩张装置可以包括一个或多个柔性构件。 膨胀装置的一个或多个部分可以与身体中的装置分离，并且扩张装置可以将一个或多个植入物释放到体内。 在这些变型中的一些中，扩张装置可以另外用于扩展身体内的一个或多个植入物或其他装置。 在一些变型中，扩张装置可以释放可以将扩张的组织保持在扩张构型中的一种或多种物质。

    Fabricating a stent from a blow molded tube
    59.
    发明申请
    Fabricating a stent from a blow molded tube 有权
    从吹塑管制造支架

    公开(公告)号：US20080300670A1

    公开(公告)日：2008-12-04

    申请号：US11809011

    申请日：2007-05-30

    Applicant: Vincent J. Gueriguian ,  David C. Gale ,  Bin Huang

    Inventor： Vincent J. Gueriguian ,  David C. Gale ,  Bin Huang

    IPC: A61F2/06

    CPC classification number: A61F2/915 ,  A61F2/91 ,  A61F2002/825 ,  A61F2002/91575

    Abstract: Disclosed is a method for fabricating a stent, the method comprising: positioning a polymeric tube inside a mold, wherein a high thermally conductive element covers at least a portion of the outer surface of the mold, the high thermally conductive element having a thermal conductivity that is greater than that of the mold; heating at least a portion of the mold; radially expanding the tube against the mold; and fabricating a stent from the radially expanded tube.

    Abstract translation: 公开了一种用于制造支架的方法，所述方法包括：将聚合物管定位在模具内，其中高导热元件覆盖模具的外表面的至少一部分，高导热元件具有导热性， 大于模具; 加热模具的至少一部分; 将管径向膨胀以抵靠模具; 并从径向膨胀的管制造支架。

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