公开(公告)号：US11938021B2

公开(公告)日：2024-03-26

申请号：US17456337

申请日：2021-11-23

Applicant: Edwards Lifesciences Corporation

Inventor： Sara Tzadok ,  Khen Perlmutter ,  Darshin S. Patel ,  Boaz Manash ,  Ajay Chadha ,  Waina Michelle Chu ,  Chambory Chhe ,  Evan T. Schwartz ,  Sandip Vasant Pawar

IPC: A61F2/24 ,  A61F2/00

CPC classification number: A61F2/2412 ,  A61F2/0077 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2002/0086 ,  A61F2/243 ,  A61F2210/0076

Abstract: A prosthetic heart valve has a frame including a plurality of strut members, an inflow end, and an outflow end. A leaflet structure is situated at least partially within the frame, and a covering is disposed around an exterior of the frame. The covering includes a cushioning layer, and a first strip member folded over an inflow circumferential edge portion of the cushioning layer to form a first protective portion. A second strip member is folded over an outflow circumferential edge portion of the cushioning layer to form a second protective portion. The first strip member and the second strip member are spaced apart from each other along a longitudinal axis of the prosthetic heart valve.

公开(公告)号：US20240074851A1

公开(公告)日：2024-03-07

申请号：US18235720

申请日：2023-08-18

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Noam Nir ,  Michael Bukin ,  Boaz Manash

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2415 ,  A61F2/243 ,  A61F2/2436 ,  A61F2/9517 ,  A61F2220/0033 ,  A61F2220/0075 ,  A61F2220/0091

Abstract: In one embodiment, a prosthetic valve assembly includes an annular frame being radially expandable and compressible between a radially compressed configuration and a radially expanded configuration, a valvular structure comprising a plurality of leaflets mounted inside the annular frame, a plurality of posts mounted on an interior surface of the annular frame, and a pair of commissure attachment members extending outwardly from each post and away from each other. Each two adjacent leaflets can form a pair of commissure tabs. Each pair of commissure tabs can be attached to a corresponding pair of the commissure attachment members.

公开(公告)号：US20230201015A1

公开(公告)日：2023-06-29

申请号：US18171187

申请日：2023-02-17

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Nikolai Gurovich ,  Boaz Manash ,  Adi Carmi ,  Eran Goldberg ,  Khen Perlmutter

IPC: A61F2/95 ,  A61F2/24

CPC classification number: A61F2/9522 ,  A61F2/2418

Abstract: A docking station for a prosthetic heart valve includes a radially expandable and collapsible frame with a first plurality of struts, an inflow end portion, an outflow end portion, and a longitudinal axis. A sealing member is disposed on the outflow end portion and configured to form a seal between the docking station and a body lumen. The docking station further includes a valve seat coupled to the frame and configured to receive an expandable prosthetic valve. The valve seat includes a second plurality of struts coupled to the frame and extending in a downstream direction and angled inwardly toward the longitudinal axis of the frame.

公开(公告)号：US20220287828A1

公开(公告)日：2022-09-15

申请号：US17804403

申请日：2022-05-27

Applicant: Edwards Lifesciences Corporation

Inventor： Darshin S. Patel ,  Boaz Manash ,  Khen Perlmutter ,  Yoav Rozen ,  Dinesh L. Sirimanne ,  Zohar Kiblitski ,  Noa Axelrod Manela

IPC: A61F2/24

Abstract: Anchoring or docking devices configured to be positioned at a native valve of a human heart and to provide structural support for docking a prosthetic valve therein. The docking devices can have coiled structures that define an inner space in which the prosthetic valve can be held. The docking devices can have enlarged end regions with circular or non-circular shapes, for example, to facilitate implantation of the docking device or to better hold the docking device in position once deployed. The docking devices can be laser-cut tubes with locking wires to assist in better maintaining a shape of the docking device. The docking devices can include various features to promote friction, such as frictional cover layers. Such docking devices can have ends configured to more securely attach the cover layers to cores of the docking devices.

公开(公告)号：US11344408B2

公开(公告)日：2022-05-31

申请号：US16813637

申请日：2020-03-09

Applicant: Edwards Lifesciences Corporation

Inventor： David Maimon ,  Boaz Manash ,  Eyal Leiba ,  Ziv Yohanan ,  Yair A. Neumann ,  Anatoly Dvorsky ,  Jonathan Bar-Or ,  Oren Cohen ,  Ofir Witzman ,  Liron Tayeb ,  Elazar Levi Schwarcz ,  Noam Miller ,  Tomer Saar

IPC: A61F2/24

Abstract: An assembly can comprise a radially expandable and compressible annular frame, at least one linear actuator assembly coupled to the frame and at least one locking mechanism coupled to the frame. The linear actuator can be configured to apply a distally directed force and/or a proximally directed force to the frame to radially expand or compress the frame. The locking mechanism can comprise a first sleeve member connected to the frame at a first location, a second sleeve member having internal threads and being connected to the frame at a second location, and a first screw configured to engage the internal threads of the second sleeve member to retain the frame in a radially expanded state.

公开(公告)号：US20220110742A1

公开(公告)日：2022-04-14

申请号：US17556739

申请日：2021-12-20

Applicant: Edwards Lifesciences Corporation

Inventor： Tamir S. Levi ,  Michael Bukin ,  Noam Nir ,  Ziv Yohanan ,  Elazar Levi Schwarcz ,  Oren Cohen ,  Ofir Witzman ,  Eitan Atias ,  Noam Miller ,  Khen Perlmutter ,  Boaz Manash ,  Eyal Leiba ,  Eran Goldberg

IPC: A61F2/24

Abstract: Various mechanically expandable prosthetic heart valves, as well as deliver apparatus, delivery assemblies, and methods for implanting such prosthetic heart valves. In one example, a prosthetic heart valve includes a mechanically expandable frame, a valve structure, and an actuator. The frame includes a plurality of struts and is movable between a radially compressed state and a radially expanded state. The valve structure includes a plurality of leaflets. The actuator is coupled to the frame and comprises an actuation lumen, a locking member, and a locking element. The actuation lumen is circumferentially spaced and axially parallel to the locking member. The actuation lumen is configured for receiving an axially movable actuation shaft that can move the frame between the radially compressed state and the radially expanded state. The locking element is rotatably coupled to the locking member and is configured to lock the frame at a desired state.

公开(公告)号：US20220079750A1

公开(公告)日：2022-03-17

申请号：US17456337

申请日：2021-11-23

Applicant: Edwards Lifesciences Corporation

Inventor： Sara Tzadok (formerly Haivatov) ,  Khen Perlmutter ,  Darshin S. Patel ,  Boaz Manash ,  Ajay Chadha ,  Waina Michelle Chu ,  Chambory Chhe ,  Evan T. Schwartz ,  Sandip Vasant Pawar

IPC: A61F2/24 ,  A61F2/00

Abstract: A prosthetic heart valve has a frame including a plurality of strut members, an inflow end, and an outflow end. A leaflet structure is situated at least partially within the frame, and a covering is disposed around an exterior of the frame. The covering includes a cushioning layer, and a first strip member folded over an inflow circumferential edge portion of the cushioning layer to form a first protective portion. A second strip member is folded over an outflow circumferential edge portion of the cushioning layer to form a second protective portion. The first strip member and the second strip member are spaced apart from each other along a longitudinal axis of the prosthetic heart valve.

公开(公告)号：US20220031327A1

公开(公告)日：2022-02-03

申请号：US17503188

申请日：2021-10-15

Applicant: Edwards Lifesciences Corporation

Inventor： Boaz Manash ,  Eran Goldberg

IPC: A61B17/11 ,  A61F2/856 ,  A61F2/962

Abstract: A device may provide a fluid connection between fluid vessels, such as between an inferior vena cava and an abdominal aorta. The device may include a conduit structure for deployment in a first fluid vessel or a shunt structure for deployment within a passage between the first fluid vessel and a second fluid vessel that is adjacent to the first fluid vessel. The conduit structure may include a narrowed section to which the shunt structure is secured and in fluid connection therewith.

公开(公告)号：US11185406B2

公开(公告)日：2021-11-30

申请号：US15876053

申请日：2018-01-19

Applicant: Edwards Lifesciences Corporation

Inventor： Sara Haivatov ,  Khen Perlmutter ,  Darshin S. Patel ,  Boaz Manash ,  Ajay Chadha ,  Waina Michelle Chu ,  Chambory Chhe ,  Evan T. Schwartz ,  Sandip Vasant Pawar

IPC: A61F2/24 ,  A61F2/82 ,  A61F2/00

Abstract: A prosthetic heart valve includes a frame having a plurality of strut members, an inflow end, and an outflow end. The prosthetic heart valve further includes a leaflet structure situated at least partially within the frame, and a covering disposed around the frame. The covering has a first layer and a second layer, wherein the second layer has a plush surface. The first layer is folded over a circumferential edge portion of the second layer to form a protective portion that extends beyond the strut members in a direction along a longitudinal axis of the prosthetic heart valve.

公开(公告)号：US11135056B2

公开(公告)日：2021-10-05

申请号：US15978459

申请日：2018-05-14

Applicant: Edwards Lifesciences Corporation

Inventor： Nikolay Gurovich ,  Michael Bukin ,  Alexey M. Tsypenyuk ,  Elena Sherman ,  Dikla Kersh ,  Boaz Manash ,  Liron Tayeb ,  Ziv Yohanan ,  Alexander Barash ,  Yair A. Neumann ,  Tomer Saar

IPC: A61F2/24

Abstract: A prosthetic heart valve includes an annular frame including a plurality of strut members that is radially collapsible and expandable. A leaflet structure is situated within the frame, and includes a plurality of leaflets having opposing commissure tab portions on opposite sides of the leaflet. Each commissure tab portion is paired with an adjacent commissure tab portion of an adjacent leaflet to form one or more commissures. A commissure support element is positioned at each of the commissures, and comprise a first member and a second member that are separable from each other and configured to receive leaflets therebetween. The first and second members are detached from the frame and spaced radially inwardly from the frame such that the members contact the leaflets radially inward from the frame and limit movement of the leaflets so that they articulate at a location that is spaced radially inwardly from the frame.