Method and system for setting cardiac resynchronization therapy parameters
    51.
    发明授权
    Method and system for setting cardiac resynchronization therapy parameters 有权
    设置心脏再同步治疗参数的方法和系统

    公开(公告)号:US07869873B2

    公开(公告)日:2011-01-11

    申请号:US11681244

    申请日:2007-03-02

    CPC classification number: A61N1/3627 A61N1/3682 A61N1/3684

    Abstract: A method or system for computing and/or setting optimal cardiac resynchronization pacing parameters as derived from intrinsic conduction data is presented. The intrinsic conduction data includes intrinsic atrio-ventricular and interventricular delay intervals which may be collected via the sensing channels of an implantable cardiac device. Among the parameters which may be optimized in this manner are an atrio-ventricular delay interval and a biventricular offset interval. In one of its aspects, the invention provides for computing optimum pacing parameters for patients having some degree of AV block or with atrial conduction deficits. Another aspect of the invention relates to a pacing mode and configuration for providing cardiac resynchronization therapy to patients with a right ventricular conduction disorder.

    Abstract translation: 提出了一种用于计算和/或设置从内在传导数据导出的最佳心脏再同步起搏参数的方法或系统。 内在传导数据包括可通过可植入心脏装置的感测通道收集的本征心室和室间延迟间隔。 可以以这种方式优化的参数是心房延迟间隔和双心室偏移间隔。 在其一个方面,本发明提供了对具有一定程度的AV阻滞或具有心房传导缺陷的患者计算最佳起搏参数。 本发明的另一方面涉及用于向患有右心室传导障碍的患者提供心脏再同步治疗的起搏模式和配置。

    Cardiac resynchronization therapy parameter optimization
    55.
    发明申请
    Cardiac resynchronization therapy parameter optimization 有权
    心脏再同步治疗参数优化

    公开(公告)号:US20100023078A1

    公开(公告)日:2010-01-28

    申请号:US11338935

    申请日:2006-01-25

    CPC classification number: A61N1/3627 A61N1/36585 A61N1/3684

    Abstract: Systems and methods involve determination of CRT parameters using a number of CRT optimization processes. Each CRT optimization process attempts to return recommended parameters. The CRT parameters are determined based on the recommended parameters returned by one or more of the CRT optimization processes. The CRT optimization processes may be sequentially implemented and the CRT parameters may be determined based on the recommended parameters returned by a first CRT optimization process to return recommended parameters. The CRT parameters may be determined based on a combination of the recommended parameters returned. The CRT optimization processes implemented may be selected from available CRT optimization processes based on patient conditions.

    Abstract translation: 系统和方法涉及使用多个CRT优化过程来确定CRT参数。 每个CRT优化过程都会尝试返回推荐的参数。 CRT参数根据一个或多个CRT优化过程返回的推荐参数来确定。 可以顺序地实施CRT优化过程,并且可以基于由第一CRT优化过程返回的推荐参数来返回推荐参数来确定CRT参数。 可以基于返回的推荐参数的组合来确定CRT参数。 可以根据患者条件从可用的CRT优化过程中选择实现的CRT优化处理。

    SELECTIVE RESYNCHRONIZATION THERAPY OPTIMIZATION BASED ON USER PREFERENCE
    56.
    发明申请
    SELECTIVE RESYNCHRONIZATION THERAPY OPTIMIZATION BASED ON USER PREFERENCE 有权
    基于用户偏好的选择性修复治疗优化

    公开(公告)号:US20100010557A1

    公开(公告)日:2010-01-14

    申请号:US12565344

    申请日:2009-09-23

    CPC classification number: A61N1/3627 A61N1/36564 A61N1/3682 A61N1/3684

    Abstract: A method and system for calculating an atrio-ventricular delay interval based upon an inter-atrial delay exhibited by a patient's heart. The aforementioned atrio-ventricular delay interval may optimize the stroke volume exhibited by a patient's heart. The aforementioned atrio-ventricular delay interval may be blended with another atrio-ventricular delay interval that may optimize another performance characteristic, such as left ventricular contractility. Such blending may include finding an arithmetic mean, geometric mean, or weighted mean of two or more proposed atrio-ventricular delay intervals.

    Abstract translation: 一种用于根据患者心脏表现的心房间延迟来计算心房延迟间隔的方法和系统。 上述的心室延迟间隔可以优化患者心脏展示的搏动量。 上述房室延迟间隔可以与可以优化另一性能特征(例如左心室收缩力)的另一心房延迟间隔混合。 这种混合可以包括找到两个或更多个提出的心房延迟间隔的算术平均值,几何平均值或加权平均值。

    Electrogram morphology-based CRT optimization
    57.
    发明授权
    Electrogram morphology-based CRT optimization 有权
    基于电图形态的CRT优化

    公开(公告)号:US07555340B2

    公开(公告)日:2009-06-30

    申请号:US11097460

    申请日:2005-04-01

    CPC classification number: A61N1/368 A61N1/3682 A61N1/371

    Abstract: A method and system for determining an optimum atrioventricular delay (AVD) interval and/or ventriculo-ventricular delay (VVD) intervals for delivering ventricular resynchronization pacing in an atrial tracking or atrial sequential pacing mode. Evoked response electrograms recorded at different AVD and VVD intervals are used to determine the extent of paced and intrinsic activation.

    Abstract translation: 一种用于确定用于在心房跟踪或心房顺序起搏模式中递送心室再同步起搏的最佳房室延迟(AVD)间隔和/或心室 - 心室延迟(VVD)间隔的方法和系统。 以不同的AVD和VVD间隔记录的诱发反应电图用于确定起搏和内在激活的程度。

    Monitoring Right Ventricular Hemodynamic Function During Pacing Optimization
    58.
    发明申请
    Monitoring Right Ventricular Hemodynamic Function During Pacing Optimization 有权
    在起搏优化过程中监测右心室血流动力学功能

    公开(公告)号:US20090118783A1

    公开(公告)日:2009-05-07

    申请号:US12235220

    申请日:2008-09-22

    Abstract: Method and systems related to monitoring right ventricular function during pacing by a cardiac rhythm management device are described. One or more pacing parameters are selected to provide cardiac resynchronization therapy. For example, the one or more pacing parameters may be selected to provide an optimal or improved therapy. The heart is paced using the selected pacing parameters. While pacing with the selected parameters, pressure is sensed via a pressure sensor disposed the pulmonary artery. The sensed pressure is analyzed to determine right ventricular function achieved during the pacing using the selected pacing parameters. A signal, such as an alert signal or control signal, is generated based on the right ventricular function achieved during the pacing.

    Abstract translation: 描述了通过心律管理装置在起搏期间监测右心室功能相关的方法和系统。 选择一个或多个起搏参数以提供心脏再同步治疗。 例如,可以选择一个或多个起搏参数以提供最佳或改进的治疗。 心脏使用所选择的起搏参数进行起搏。 在使用所选参数进行起搏时,通过设置肺动脉的压力传感器检测压力。 分析检测到的压力以确定使用所选择的起搏参数在起搏期间获得的右心室功能。 基于在起搏期间实现的右心室功能,产生诸如警报信号或控制信号的信号。

    Automatic capture verification using electrocardiograms sensed from multiple implanted electrodes
    59.
    发明授权
    Automatic capture verification using electrocardiograms sensed from multiple implanted electrodes 失效
    使用从多个植入电极感测的心电图进行自动捕获验证

    公开(公告)号:US07509170B2

    公开(公告)日:2009-03-24

    申请号:US11124972

    申请日:2005-05-09

    CPC classification number: A61N1/3712 A61N1/365

    Abstract: Cardiac monitoring and/or stimulation methods and systems that provide one or more of monitoring, diagnosing, defibrillation, and pacing. Cardiac signal separation is employed for automatic capture verification using cardiac activation sequence information. Devices and methods sense composite cardiac signals using implantable electrodes. A source separation is performed using the composite signals. One or more signal vectors are produced that are associated with all or a portion of one or more cardiac activation sequences based on the source separation. A cardiac response to the pacing pulses is classified using characteristics associated with cardiac signal vectors and the signals associated with the vectors. Further embodiments may involve classifying the cardiac response as capture or non-capture, fusion or intrinsic cardiac activity. The characteristics may include an angle or an angle change of the cardiac signal vectors, such as a predetermined range of angles of the one or more cardiac signal vectors.

    Abstract translation: 提供一种或多种监测,诊断,除颤和起搏的心脏监测和/或刺激方法和系统。 心脏信号分离被用于使用心脏激活序列信息的自动捕获验证。 装置和方法使用可植入电极感测复合心脏信号。 使用复合信号进行源分离。 产生与基于源分离的一个或多个心脏激活序列的全部或一部分相关联的一个或多个信号载体。 使用与心脏信号矢量相关联的特征和与矢量相关联的信号来分类对起搏脉冲的心脏反应。 进一步的实施方案可以包括将心脏反应分类为捕获或非捕获,融合或内在心脏活动。 特征可以包括心脏信号矢量的角度或角度变化,例如一个或多个心脏信号矢量的预定角度范围。

    Closed loop impedance-based cardiac resynchronization therapy systems, devices, and methods
    60.
    发明授权
    Closed loop impedance-based cardiac resynchronization therapy systems, devices, and methods 有权
    基于闭环阻抗的心脏再同步治疗系统,装置和方法

    公开(公告)号:US07440803B2

    公开(公告)日:2008-10-21

    申请号:US11264941

    申请日:2005-11-02

    Abstract: This document discusses, among other things, systems, devices, and methods measure an impedance and, in response, adjust an atrioventricular (AV) delay or other cardiac resynchronization therapy (CRT) parameter that synchronizes left and right ventricular contractions. A first example uses parameterizes a first ventricular volume against a second ventricular volume during a cardiac cycle, using a loop area to create a synchronization fraction (SF). The CRT parameter is adjusted in closed-loop fashion to increase the SF. A second example measures a septal-freewall phase difference (PD), and adjusts a CRT parameter to decrease the PD. A third example measures a peak-to-peak volume or maximum rate of change in ventricular volume, and adjusts a CRT parameter to increase the peak-to-peak volume or maximum rate of change in the ventricular volume.

    Abstract translation: 本文件还讨论了系统,设备和方法测量阻抗,并作为响应调整房室(AV)延迟或同步左心室收缩和右心室收缩的其他心脏再同步治疗(CRT)参数。 第一个例子是使用循环区域创建同步分数(SF),在心动周期中使用第一心室容积对第二心室容积进行参数化。 CRT参数以闭环方式调整以增加SF。 第二个例子是测量隔层相位差(PD),并调整CRT参数以减少PD。 第三个例子测量心室容积的峰 - 峰体积或最大变化率,并调整CRT参数以增加心室容积的峰 - 峰体积或最大变化率。

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