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公开(公告)号：US10478545B2
公开(公告)日：2019-11-19
申请号：US15869296
申请日：2018-01-12
Applicant: Medtronic, Inc.
Inventor： Bryant J. Pudil , Martin T. Gerber , David B. Lura , Thomas E. Meyer
IPC: A61M1/16 , B01D15/18 , B01D15/22 , B01J39/12 , B01J20/06 , B01J20/08 , B01J20/20 , B01J20/02 , B01J20/28 , G01N30/60
Abstract: Parallel modules for in-line recharging of sorbent materials using alternate duty cycles for a sorbent cartridge. The sorbent cartridge can have two or more modules contained therein having connectors connecting each of the modules. One or more of the modules can be reusable and the sorbent materials therein can be recharged.
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公开(公告)号：US20190328952A1
公开(公告)日：2019-10-31
申请号：US16270884
申请日：2019-02-08
Applicant: Medtronic, Inc.
Inventor： Martin T. Gerber
Abstract: The present invention relates to a multi-stage blood purification apparatus designed to remove substances from a bodily fluid of a subject. In one aspect, the present invention relates to a sorbent stage containing a sorbent material by which a substance, or substances, is removed from a bodily fluid when in contact with the bodily fluid. In another aspect, the present invention provides a multi-stage blood purification apparatus containing a sorbent stage and a membrane stage. Further, methods of purifying a bodily fluid utilizing apparatuses of the present disclosure are provide.
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公开(公告)号：US20190201810A1
公开(公告)日：2019-07-04
申请号：US16353202
申请日：2019-03-14
Applicant: Medtronic, Inc.
Inventor： Martin T. Gerber , Christopher M. Hobot
Abstract: An apparatus and method for replenishing urease in a sorbent cartridge for use in sorbent dialysis. The system is configured to allow insertion of a urease pouch, injection of a urease solution, or addition of a urease cartridge, into a dialysis cabinet containing a dialysis flow loop. The urease can be dissolved and the resulting urease solution added to the sorbent cartridge in the flow loop to replenish the urease within the sorbent cartridge. The sorbent cartridge can also comprise other, rechargeable, sorbent materials for removing toxins other than urea from spent dialysate.
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公开(公告)号：US10335534B2
公开(公告)日：2019-07-02
申请号：US15333267
申请日：2016-10-25
Applicant: Medtronic, Inc.
Inventor： Amy Roettger , VenKatesh R. Manda , John Burnes , Rebecca Poindexter , Martin T. Gerber
Abstract: Systems and methods are provided for determining an estimated risk of arrhythmia during or after dialysis based on changes in serum potassium concentration of a patient and an amount of fluid removed from the patient during dialysis. The systems and methods allow for a determination of a risk that arrhythmia will occur due to the changes in potassium and fluid volume of a patient during dialysis, and for optimizing a dialysis prescription in order to minimize the risk of arrhythmia.
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公开(公告)号：US10258728B2
公开(公告)日：2019-04-16
申请号：US15265001
申请日：2016-09-14
Applicant: Medtronic, Inc.
Inventor： Martin T. Gerber
Abstract: Systems and methods are provided for performing selective sorbent-based regeneration of dialysate. The systems and method provide for dialysate regeneration to be carried out intermittently throughout a dialysis session, decreasing the necessary amounts of sorbent materials and infusates to conduct dialysis. The system and methods allow for regeneration of dialysate as needed based on the concentration of waste species in the dialysate, allowing for effective treatment with a decreased need for sorbent materials.
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Patent Agency Ranking
公开(公告)号：US20190091394A1
公开(公告)日：2019-03-28
申请号：US16202940
申请日：2018-11-28
Applicant: Medtronic, Inc.
Inventor： Thomas E. Meyer , David B. Lura , Bryant J. Pudil , Martin T. Gerber
Abstract: A portable dialysis cabinet for use in dialysis. The portable dialysis cabinet can have a size and weight that facilitates easy movement of the cabinet from one location to another with relative ease. The portable dialysis cabinet can have additional features necessary to facilitate portability, such as wheels and a handle. In general, the portable dialysis cabinet can contain all the necessary components for performing a dialysis session.
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公开(公告)号：US20190001303A1
公开(公告)日：2019-01-03
申请号：US16047245
申请日：2018-07-27
Applicant: Medtronic, Inc.
Inventor： Bryant J. Pudil , Martin T. Gerber , Christopher M. Hobot
CPC classification number: B01J20/3475 , A61M1/1696 , B01J20/0211 , B01J20/3483 , B01J39/09
Abstract: Methods and related apparatuses for sorbent recharging are provided. The methods and related apparatuses for recharging can recharge a specific rechargeable layer or module of a sorbent material such as zirconium phosphate in a sorbent cartridge. The methods and apparatuses include a fluid source containing at least one recharging fluid, wherein the fluid source is fluidly connectable to at least one rechargeable sorbent module for use in sorbent dialysis in a fluid flow path. The methods and apparatuses include passing a single solution through the zirconium phosphate for ion exchanges, resulting in zirconium phosphate to maintain a substantially consistent pH in a dialysate used during dialysis.
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公开(公告)号：US20180214623A1
公开(公告)日：2018-08-02
申请号：US15831530
申请日：2017-12-05
Applicant: Medtronic, Inc.
Inventor： Martin T. Gerber
CPC classification number: A61M1/1696 , B01D15/203 , B01J20/0211 , B01J20/0292 , B01J20/20 , B01J20/3416 , B01J20/3433 , B01J20/3475
Abstract: The invention relates to systems and methods for recharging sorbent materials and other rechargeable dialysis components. The systems and methods include rechargers, flow paths, and related components for connecting multiple rechargers together to sharing infrastructure and resources. The rechargeable dialysis components can include zirconium phosphate, zirconium oxide, and other sorbent cartridge materials including any combination thereof or any other rechargeable component of a dialysis system. Additionally, a single-use cartridge or a multi-use cartridge can be used in the present invention.
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公开(公告)号：US20180075299A1
公开(公告)日：2018-03-15
申请号：US15677536
申请日：2017-08-15
Applicant: Medtronic, Inc.
Inventor： Martin T. Gerber , David B. Lura , Shawn Kelley
Abstract: The invention relates to a gas bubble detector for determining gas bubbles in a fluid. The gas bubble detector can be used in any application requiring a determination whether gas bubbles exist in the fluid. The gas bubble detector has a photodetector, a light source, and a chamber in which the presence of gas bubbles are detected.
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公开(公告)号：US20180074028A1
公开(公告)日：2018-03-15
申请号：US15677645
申请日：2017-08-15
Applicant: Medtronic, Inc.
Inventor： Martin T. Gerber , David B. Lura , Shawn Kelley
CPC classification number: G01N31/223 , A61B5/08 , G01N1/22 , G01N21/783
Abstract: The invention relates to a colorimetric gas detector for determining and monitoring gaseous substances. The colorimetric gas detector can be used in any application requiring the detection of substances in a gaseous environment. The colorimetric gas detector has a photodetector, a light source positioned opposite to the photodetector, and a receiving slot for positioning a colorimetric media between the camera and the light source.
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