公开(公告)号：US08541197B2

公开(公告)日：2013-09-24

申请号：US12517971

申请日：2007-12-10

Applicant: Reeta Prusty Rao ,  Samuel Michael Politz

Inventor： Reeta Prusty Rao ,  Samuel Michael Politz

IPC: C12Q1/18 ,  C12Q1/02

CPC classification number: C12N1/18 ,  A01K67/0336 ,  A01K2227/703 ,  A01K2267/03 ,  C12Q1/18 ,  G01N2333/395 ,  G01N2333/43534

Abstract: The present invention is based on the discovery of a two organism model system that can be used to identify virulence factors. The system is also useful in the process of drug delivery. More specifically, we have established valid fungal infection in caenorhabditis elegans with an invading pathogen, the yeast Saccharomyces cerevisiae. Because both species are genetic model organisms, the assay can be used to identify host and virulence factors involved in such interactions.

Abstract translation: 本发明基于可用于鉴定毒力因子的两种生物体模型系统的发现。 该系统在药物递送过程中也是有用的。 更具体地说，我们已经在具有入侵病原体，酵母酿酒酵母的秀丽隐杆线虫中建立了有效的真菌感染。 因为这两种物种都是遗传模式生物，所以该测定可用于鉴定参与这种相互作用的宿主和毒力因子。

公开(公告)号：US20130137759A1

公开(公告)日：2013-05-30

申请号：US13582917

申请日：2011-03-04

Applicant: Pamela J. Weathers

Inventor： Pamela J. Weathers

IPC: A61K36/282 ,  A61K45/06 ,  A61K31/366

CPC classification number: A61K36/282 ,  A61K31/366 ,  A61K45/06 ,  Y02A50/411 ,  Y02A50/423 ,  A61K2300/00

Abstract: The present invention features compositions and methods for treatment of parasitic diseases and cancer. The compositions include Artemisia annua tissue and a pharmaceutically acceptable carrier. The methods provide an efficient delivery system for artemisinin and related compounds.

Abstract translation: 本发明的特征在于用于治疗寄生虫病和癌症的组合物和方法。 组合物包括青蒿组织和药学上可接受的载体。 该方法为青蒿素及相关化合物提供了有效的输送系统。

公开(公告)号：US20130078600A1

公开(公告)日：2013-03-28

申请号：US13598066

申请日：2012-08-29

Applicant: Gregory S. Fischer ,  Hao Su ,  Laurie Dickstein-Fischer ,  Kevin Harrington ,  Elizabeth V. Alexander

Inventor： Gregory S. Fischer ,  Hao Su ,  Laurie Dickstein-Fischer ,  Kevin Harrington ,  Elizabeth V. Alexander

IPC: G09B19/00

CPC classification number: G09B19/00

Abstract: Methods and systems for observing/analyzing, interactive behavior are presented. In one instance, the method for observing/analyzing interactive behavior includes interacting, using a robot, with a subject and obtaining data from interaction between the subject and the robot, the data from the data acquisition components, the data being used for diagnosis and/or charting progress. In one instance, the robot includes data acquisition components, interaction inducing components (such as, but not limited to, movable eyelids, movable appendages, sound generating components), a control component operatively connected to the interaction inducing components and a processing component operatively connected to the control component and the data acquisition components, the processing component being configured to obtain data from the data acquisition components, the data being used for diagnosis and/or charting progress. In one instance, the robot is integrated with a computer-aided system for diagnosis, monitoring, and therapy.

Abstract translation: 介绍了观察/分析，交互行为的方法和系统。 在一个实例中，用于观察/分析交互行为的方法包括使用机器人与主体进行交互，并从主体和机器人之间的交互获取数据，来自数据采集组件的数据，用于诊断的数据和/ 或制图进度。 在一个实例中，机器人包括数据采集部件，相互作用诱导部件（例如但不限于可移动的眼睑，可动附件，声音产生部件），可操作地连接到相互作用诱导部件的控制部件和可操作地连接的处理部件 所述处理部件被配置为从所述数据获取部件获取数据，所述数据被用于诊断和/或绘制进度。 在一个实例中，机器人与用于诊断，监测和治疗的计算机辅助系统集成。

公开(公告)号：US20100288943A1

公开(公告)日：2010-11-18

申请号：US12668938

申请日：2008-07-14

Applicant: Christopher R. Lambert

Inventor： Christopher R. Lambert

IPC: G01N21/64 ,  C09K11/06

CPC classification number: G01N33/52

Abstract: The present invention is a low-cost, easily deployed, degradable taggant that can be dispersed over a wide area to serve as a witness to activity in the area and for queuing of other sensors. The taggant enables nearly real-time change detection within the treated area using one or more simple optical sensing techniques.

Abstract translation: 本发明是一种低成本，容易部署，可降解的标签牌，其可以分散在广泛的区域上，以作为该区域中的活动和其他传感器的排队的见证。 标签牌使用一个或多个简单的光学感测技术在处理的区域内实现几乎实时的变化检测。

公开(公告)号：US20100277339A1

公开(公告)日：2010-11-04

申请号：US12664844

申请日：2008-06-13

Applicant: David Cyganski ,  R. James Duckworth ,  John A. Orr ,  William R. Michalson

Inventor： David Cyganski ,  R. James Duckworth ,  John A. Orr ,  William R. Michalson

IPC: G08B5/22

CPC classification number: G01S1/026 ,  G01S5/02

Abstract: Systems and methods are described herein for determining the location of a transmitter by jointly and collectively processing the full sampled signal data from a plurality of receivers to form a single solution.

Abstract translation: 这里描述了用于通过共同和共同地处理来自多个接收器的全采样信号数据来确定发射机的位置以形成单个解决方案的系统和方法。

公开(公告)号：US20100033565A1

公开(公告)日：2010-02-11

申请号：US12304520

申请日：2007-06-18

Applicant: Souheil Benzerrouk ,  Reinhold Ludwig ,  Diran Apelian

Inventor： Souheil Benzerrouk ,  Reinhold Ludwig ,  Diran Apelian

IPC: G06K9/00 ,  H04N7/18 ,  H04N5/33 ,  G01N21/00

CPC classification number: G06T7/0004 ,  G06T2207/30164

Abstract: A pulsed thermography defect detection apparatus including active and passive infrared (IR) thermography for non-destructive testing (NDT) of powdermetallic (P/M) components for on-line and off-line inspection.

Abstract translation: 一种脉冲热成像缺陷检测装置，包括用于在线和离线检查的粉末金属（P / M）组分的无损检测（NDT）的主动和被动红外（IR）热成像。

公开(公告)号：US20100022882A1

公开(公告)日：2010-01-28

申请号：US12299540

申请日：2007-05-04

Applicant: Reginald James Duckworth ,  Philip Cordeiro ,  Peder C. Pedersen

Inventor： Reginald James Duckworth ,  Philip Cordeiro ,  Peder C. Pedersen

IPC: A61B8/14 ,  G06F1/26

CPC classification number: A61B8/00 ,  A61B5/6805 ,  A61B8/42 ,  A61B8/4281 ,  A61B8/4472 ,  A61B8/462 ,  A61B8/467 ,  A61B8/483 ,  A61B8/546 ,  A61B8/56 ,  A61B8/565 ,  A61B2017/00203 ,  A61B2560/0209 ,  A61B2560/0431

Abstract: An untethered ultrasound imaging system having selectable command control and wireless component connection and image transmission. Ultrasound data collected by the ultrasound system can be augmented with additional sensor data.

Abstract translation: 具有可选命令控制和无线组件连接和图像传输的无连接超声成像系统。 超声系统收集的超声数据可以用额外的传感器数据进行增强。

公开(公告)号：US20090017529A1

公开(公告)日：2009-01-15

申请号：US12172781

申请日：2008-07-14

Applicant: Pamela J. Weathers ,  Melissa J. Towler

Inventor： Pamela J. Weathers ,  Melissa J. Towler

IPC: C12M1/00

CPC classification number: C12M23/14 ,  C12M23/34

Abstract: A flexible wall bioreactor is described that uses a small droplet size mist unit, a lower rate ambient air flow rate, and a flexible wall culture chamber to provide an environment that allows for the growth of dense root matrix, shoot cultures, and 2 and 3 dimensional animal tissues.

Abstract translation: 描述了一种柔性壁生物反应器，其使用小液滴尺寸雾单元，较低速率的环境空气流速和柔性壁培养室，以提供允许密集根基质，枝条培养物和2和3的生长的环境 三维动物组织。

公开(公告)号：US07292189B2

公开(公告)日：2007-11-06

申请号：US11223079

申请日：2005-09-08

Applicant: John A. Orr ,  William R. Michalson ,  David Cyganski ,  R. James Duckworth

Inventor： John A. Orr ,  William R. Michalson ,  David Cyganski ,  R. James Duckworth

IPC: G01S3/02

CPC classification number: G01S5/0215 ,  G01S5/06

Abstract: The invention relates to a method of signal analysis that determines the location of a transmitter and to devices that implement the method. The method includes receiving by at least three receivers, from a transmitter, a first continuous-time signal having a first channel. The first channel includes a first plurality of signal carriers having known relative initial phases and having known frequencies which are periodically spaced and which are orthogonal to one another within a first frequency range. The signal analysis method also includes determining the phase shifts of the carriers of the first channel resulting from the distance the carriers traveled in reaching the first receiver. Analysis of the phase shifts yields time difference of arrival information amongst the receivers, which is further processed to determine the location of the transmitter.

Abstract translation: 本发明涉及一种信号分析方法，其确定发射机的位置以及实现该方法的设备。 该方法包括由至少三个接收机从发射机接收具有第一信道的第一连续时间信号。 第一信道包括具有已知的相对初始相位的第一多个信号载波，并具有周期性间隔的已知频率，并且在第一频率范围内彼此正交。 信号分析方法还包括确定由载波在到达第一接收机时行进的距离导致的第一信道的载波的相移。 相移的分析产生接收机之间到达信息的时间差，其进一步被处理以确定发射机的位置。

公开(公告)号：US07068054B2

公开(公告)日：2006-06-27

申请号：US10373663

申请日：2003-02-24

Applicant: Loutfallah Georges Chedid ,  Makhlouf M. Makhlouf ,  Richard D. Sisson, Jr.

Inventor： Loutfallah Georges Chedid ,  Makhlouf M. Makhlouf ,  Richard D. Sisson, Jr.

IPC: G01R27/08 ,  G01N27/04

CPC classification number: G01N33/20 ,  G01N27/041

Abstract: An alloy solute sensor probe, measurement system and measurement method are disclosed for directly measuring solute concentration profiles in conductive material components at elevated processing temperatures. The disclosed device and method permit direct, real-time non-destructive measurement of solute concentration profiles in treated surfaces in alloy components. In disclosed embodiments, a novel concentric carbon sensor and rod-shaped carbon sensor are disclosed which employ AC frequencies for probing the subsurface region of alloy samples to determine carbon concentration profiles at steel surfaces from measurements of alloy resistivity profiles. Results of carbon profile measurements obtained with the disclosed device and method compare favorably with conventional destructive analytical measurements made on post-processed samples. The sensor probe and method may be utilized to determine solute concentration profiles with a variety of solute materials and alloy compositions and may be advantageously employed in alloy surface processing, carburization heat treatments, induction heating and fatigue fracture applications.

Abstract translation: 公开了一种合金溶质传感器探针，测量系统和测量方法，用于在升高的处理温度下直接测量导电材料组分中的溶质浓度分布。 所公开的装置和方法允许在合金部件中处理的表面中的溶质浓度分布的直接的，实时的非破坏性测量。 在公开的实施例中，公开了一种新颖的同心碳传感器和棒状碳传感器，其采用AC频率来探测合金样品的地下区域，以根据合金电阻率分布的测量来确定钢表面的碳浓度分布。 使用所公开的装置和方法获得的碳分布测量结果与在后处理样品上进行的常规破坏性分析测量结果相比较。 可以使用传感器探针和方法来测定各种溶质和合金组成的溶质浓度分布，并且可以有利地用于合金表面处理，渗碳热处理，感应加热和疲劳断裂应用中。