公开(公告)号：US20200282726A1

公开(公告)日：2020-09-10

申请号：US16645008

申请日：2018-07-03

Applicant: Nidec Corporation ,  National University Corporation Saitama University

Inventor： Kenji MAEDA ,  Masaji NAKATANI ,  Masaya TAKASAKI

IPC: B41J2/14 ,  H01L41/04 ,  H01L41/053 ,  H01L41/09

Abstract: [Object] A liquid agent application device capable of adjusting the displacement amount of a diaphragm is provided. [Solution] The liquid agent application device 10 includes a diaphragm 12 that changes the internal volume of a liquid agent reservoir 11, and a drive unit 13 located on the diaphragm 12. The drive unit 13 includes a driving piezoelectric element 20 that vibrates in response to application of a drive voltage signal, and a horn 21 that vibrates together with the driving piezoelectric element 20.

公开(公告)号：US20200217826A1

公开(公告)日：2020-07-09

申请号：US16721185

申请日：2019-12-19

Applicant: National University Corporation Saitama University ,  Hitachi High-Tech Science Corporation

Inventor： Masami SHIBUKAWA

IPC: G01N30/54

Abstract: The present invention provides a highly versatile method for amino acid analysis, the method enabling separation and analysis of amino acids in a sample with high precision in a shorter time. This method is a method for amino acid analysis, the method including a step of allowing a sample containing a plurality of amino acids to flow together with an eluent 2 through a separation column 4 packed with a cation exchange resin, thereby separating the amino acids, and a step of detecting the separated amino acids, wherein the eluent 2 is an eluent containing a divalent or higher inorganic acid, a cation source, and water, and having a pH of 5.0 or lower, and the sample is allowed to flow through the separation column 4 heated by applying a temperature gradient including a temperature region of 100° C. or higher.

公开(公告)号：US20190105739A1

公开(公告)日：2019-04-11

申请号：US16149631

申请日：2018-10-02

Applicant: Shin-Etsu Polymer Co., Ltd. ,  Shin-Etsu Chemical Co., Ltd. ,  National University Corporation Saitama University

Inventor： Junichi IKENO ,  Yohei YAMADA ,  Hideki SUZUKI ,  Hitoshi NOGUCHI

IPC: B23K26/53 ,  B23K26/00 ,  B23K26/08

Abstract: A substrate manufacturing method capable of easily obtaining a thin magnesium oxide single crystal substrate is provided. Performed is a first step of disposing a laser condensing means on a surface of a magnesium oxide single crystal substrate (20) of magnesium oxide to be irradiated in a non-contact manner, the laser condensing means being for condensing a laser beam. Then, a second step of causing planar peeling from a surface side of the magnesium oxide single crystal substrate (20) to be irradiated is performed. In this second step, a laser beam (B) is irradiated to the surface of the single crystal substrate (20) and the laser beam (B) is condensed into an inner portion of the single crystal substrate (20) under designated irradiation conditions. Simultaneously with the irradiation and the condensation, the laser condensing means (14) and the single crystal substrate (20) are two-dimensionally moved relatively to each other. In this way, processing mark lines (LK), each of which is composed in such a manner that processing marks (K) formed by thermal processing are formed in line at an inner portion of a single crystal member, are formed in parallel to one another. At this time, overlapped line portions (DK) in which the processing marks (K) overlap one another are formed in at least a part of the processing mark lines (LK), whereby the planar peeling is caused from the irradiated surface (20r) side.

公开(公告)号：US20190024746A1

公开(公告)日：2019-01-24

申请号：US15757413

申请日：2016-08-05

Applicant: NATIONAL UNIVERSITY CORPORATION SAITAMA UNIVERSITY

Inventor： Masato Saitoh

IPC: F16F3/04 ,  F16F1/12 ,  F16F1/04 ,  F16F15/067

Abstract: In the spring mechanism, the negative spring mechanism biasing the loading plate to the positive side in the z-direction has the spring shaft and interspring. The spring shaft is rotatably connected to the fixed part and is connected through the slider with respect to the loading plate so that it can rotate and can move in the x-direction. The connection part with the loading plate is positioned on the positive side in the z-direction and on the positive side in the x-direction relative to the connection part with the fixed part. An elastic force countering the compression is generated by the spring shaft. The interspring is connected to the loading plate and is connected through the slider to the spring shaft. It generates an elastic force countering the displacement to the positive side in the x-direction of the connection part of the spring shaft with the loading plate.

公开(公告)号：US20180362718A1

公开(公告)日：2018-12-20

申请号：US15991033

申请日：2018-05-29

Applicant: QUARRYMEN&Co. Inc. ,  Saitama University

Inventor： Miho Suzuki ,  Ken Hatano ,  Shojiro Yoshida ,  Yasuhiro Yamashita

IPC: C08G83/00 ,  A61K47/56 ,  A61K47/42 ,  A61K49/00

Abstract: The present invention is related to a targeted type shell for drug delivery system. The object of the present invention is to provide the targeted type shell for DDS, which comprises a carbosilane dendrimer containing a silole produced by which is formed by utilizing the reaction between thiol group and alkyl halide, and a targeted protein containing a labeled proteins such as green fluorescent protein with a target recognition site. The shell may incorporate compounds having a variety of molecular weight and biopolymers, and selectively deliver them into targeted cells.

公开(公告)号：US09982254B2

公开(公告)日：2018-05-29

申请号：US14279788

申请日：2014-05-16

Applicant: Saitama University ,  Nikon Corporation

Inventor： Naoto Nemoto ,  Yuuya Yotsumoto

IPC: C07K14/435 ,  C12N15/10 ,  C07K14/47

CPC classification number: C12N15/1062 ,  C07K14/435 ,  C07K14/4702

Abstract: The present invention improves in vitro virus synthesis efficiency and stability of mRNA derived from screened cDNA in a cDNA display method to improve the efficiency and reliability of the production of a peptide by a molecular evolutionary engineering technique. Provided is a ligand which comprises three fingers formed from antiparallel β-sheets and a loop region intercalated between the antiparallel β-sheets, wherein at least a fingertip part formed by the loop region of each of the fingers is bound to the target molecule, and wherein the ligand comprises the amino acid sequence of SEQ ID NO: 1. In the amino acid sequence of SEQ ID NO: 1, X7 represents an arbitrary amino acid residue that constitutes the fingertip part of each of the fingers, each numeric character represents the number of amino acid residues, and X7 and X4 are not composed of the same amino acid residues as each other.

公开(公告)号：US20180065901A1

公开(公告)日：2018-03-08

申请号：US15559625

申请日：2016-03-18

Applicant: JXTG NIPPON OIL & ENERGY CORPORATION ,  NATIONAL UNIVERSITY CORPORATION SAITAMA UNIVERSITY

Inventor： Hideki KUROKAWA ,  Tatsuya ICHIJO ,  Nobuhiro KIMURA

IPC: C07C5/333 ,  C07C11/167 ,  B01J23/62 ,  B01J21/02

CPC classification number: C07C5/3337 ,  B01J21/02 ,  B01J23/62 ,  C07C11/167 ,  C07C2523/62

Abstract: A method for producing a conjugated diene according to one aspect of the present invention comprises a step of contacting a raw material gas containing an olefin with a dehydrogenation catalyst to obtain a product gas containing a conjugated diene. In the production method, the dehydrogenation catalyst contains Al, a group 14 metal element, and Pt, and a content of the group 14 metal element in terms of oxide in the dehydrogenation catalyst is 9% by mass or more and 50% by mass or less based on the total mass of the dehydrogenation catalyst.

公开(公告)号：US20170093307A1

公开(公告)日：2017-03-30

申请号：US15311616

申请日：2015-02-23

Applicant: NATIONAL UNIVERSITY CORPORATION SAITAMA UNIVERSITY

Inventor： Takeshi Mizuno

IPC: H02N15/00

CPC classification number: H02N15/00

Abstract: A magnetic levitation device includes a pair of magnets, a displacement detection means, and a control means. The pair of magnets generate magnetic force for supporting a ferromagnet in a noncontact manner. The displacement detection means detect the displacement of the ferromagnet in a lateral shift direction. The control means suppresses the vibration of the ferromagnet in a lateral shift direction. The control means controls the pair of magnets so that a stronger magnetic force acts on the ferromagnet that is displaced in a direction departing from the center of the vibration than when the ferromagnet is displaced in a direction returning to the center of the vibration.

公开(公告)号：US20170067014A1

公开(公告)日：2017-03-09

申请号：US15121934

申请日：2015-02-26

Applicant: PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY ,  NATIONAL UNIVERSITY CORPORATION SAITAMA UNIVERSITY

Inventor： Takanori TAKEBE ,  Hideki TANIGUCHI ,  Hiroshi YOSHIKAWA

IPC: C12N5/00 ,  A61L27/38 ,  C12N5/071

CPC classification number: C12N5/0062 ,  A61L27/3886 ,  A61L27/3895 ,  A61L27/52 ,  A61L2430/26 ,  A61L2430/28 ,  C12N5/0697

Abstract: The present invention finds out find out the requirements necessary for preparing a cell condensate in vitro from a large number of cells (several ten thousand to several million cells) and provides a method of forming a cell condensate for self-organization which is capable of realizing complex higher structures (such as liver and kidney) and interactions with other organs.A method of preparing a cell condensate in vitro, comprising culturing a mixture of cells and/or tissues of a desired type in a total cell count of 400,000 or more and 100,000 to 400,000 mesenchymal cells to form a cell condensate of 1 mm or more in size. A cell condensate prepared by the above-described method. A method of preparing a three-dimensional tissue structure, comprising allowing self-organization of a cell condensate prepared by the above-described method to form a three-dimensional tissue structure that has been provided with higher structures. A gel-like support wherein the side on which culture is to be performed has a U- or V-shaped cross-section.

Abstract translation: 一种在体外制备细胞冷凝物的方法，包括在总细胞计数为40万个或更多至100,000至400,000个间充质细胞中培养所需类型的细胞和/或组织的混合物以形成1mm以上的细胞冷凝物 尺寸。 通过上述方法制备的细胞冷凝物。 一种制备三维组织结构的方法，包括允许通过上述方法制备的细胞冷凝物的自组织以形成具有较高结构的三维组织结构。 凝胶状载体，其中要进行培养的一面具有U形或V形横截面。

公开(公告)号：US20040057054A1

公开(公告)日：2004-03-25

申请号：US10334784

申请日：2003-01-02

Applicant: President of Saitama University

Inventor： Satoru Toyooka ,  Hirofumi Kadono

IPC: G01B011/02

CPC classification number: G01B9/02022 ,  G01B9/02007 ,  G01B9/02084 ,  G01B9/02095 ,  G01B11/162

Abstract: A deformation measuring method using electronic speckle pattern interferometry comprises the steps of subtracting an average intensity from the intensity in a time domain at each point of a speckle pattern image so as to compute the cosine component of intensity; subjecting the cosine component to Hilbert transform in a temporal domain so as to compute the sine component of intensity; determining the arctangent of the ratio between thus computed sine and cosine components so as to determine an object phase; carrying out an unwrapping operation; and outputting three-dimensional deformation distribution data in a displayable mode.