-
公开(公告)号：US20170306281A1
公开(公告)日：2017-10-26
申请号：US15498062
申请日：2017-04-26
Applicant: Corning Incorporated
Inventor： Gregory Roger Martin , Allison Jean Tanner
CPC classification number: C12M23/12 , C12M1/00 , C12M1/14 , C12M3/00 , C12M3/04 , C12M23/16 , C12M25/14 , C12M29/10
Abstract: A cell culture apparatus includes one or more plates having a first major surface and an opposing second major surface. The first major surface comprises a structured surface defining a plurality of wells. Each well has an interior surface defining an upper aperture and a nadir, wherein the upper aperture of each well has a diametric dimension in a range from 100 micrometers to 2000 micrometers. The apparatus also includes a plurality of spacers extending from the first major surface along a length of the bottom surface. A plurality of flow channels are defined between adjacent rails.
-
公开(公告)号：US09790465B2
公开(公告)日：2017-10-17
申请号：US14087906
申请日：2013-11-22
Applicant: CORNING INCORPORATED
Inventor： Scott Matthew Bennett , Brian Robb Douglass , Paul Ernest Gagnon, Jr. , Gregory Roger Martin , Paul Michael Szlosek , Allison Jean Tanner
Abstract: A spheroid cell culture article including: a frame having a chamber including: an opaque side wall surface; a top aperture; a gas-permeable, transparent bottom; and optionally a chamber annex surface and second bottom, and at least a portion of the transparent bottom includes at least one concave arcuate surface, is disclosed. Methods of making and using the article are also disclosed.
-
公开(公告)号：US20170151561A1
公开(公告)日：2017-06-01
申请号：US15319993
申请日：2015-06-26
Applicant: CORNING INCORPORATED
Inventor： William Joseph Lacey , Gregory Roger Martin , Wai Kin Poon , Ramana Tadepalli , Joseph Christopher Wall , Hongming Wang
IPC: B01L3/00
CPC classification number: B01L3/50851 , B01L2200/025 , B01L2200/12 , B01L2300/0829
Abstract: A microplate is fitted with a reinforcing member that enhances the rigidity of the microplate and decreases the magnitude of thermally-induced deformation. An example reinforced microplate includes a deck including a plurality of wells formed therein, and a reinforcing member attached to an underside of the deck.
-
公开(公告)号：US09040290B2
公开(公告)日：2015-05-26
申请号：US14075446
申请日：2013-11-08
Applicant: Corning Incorporated
Inventor： Gregory Roger Martin , Allison Jean Tanner
CPC classification number: C12M23/08 , C12M23/04 , C12M23/24 , C12M23/34 , C12M23/38 , C12M23/58 , C12M25/02 , C12M25/04 , C12M25/06 , C12M29/04 , C12N5/0602
Abstract: A multilayered cell culture apparatus for the culturing of cells is disclosed. The cell culture apparatus is defined as an integral structure having a plurality of cell culture chambers in combination with tracheal space(s). The body of the apparatus has imparted therein gas permeable membranes in combination with tracheal spaces that will allow the free flow of gases between the cell culture chambers and the external environment. The flask body also includes an aperture that will allow access to the cell growth chambers by means of a needle or cannula. The size of the apparatus, and location of an optional neck and cap section, allows for its manipulation by standard automated assay equipment, further making the apparatus ideal for high throughput applications.
-
公开(公告)号：US12146154B2
公开(公告)日：2024-11-19
申请号：US17005801
申请日：2020-08-28
Applicant: CORNING INCORPORATED
Inventor： Scott Matthew Bennett , Brian Robb Douglass , Paul Ernest Gagnon, Jr. , Gregory Roger Martin , Paul Michael Szlosek , Allison Jean Tanner
Abstract: A spheroid cell culture article including: a chamber including: an opaque side wall surface; a top aperture; and a gas-permeable, liquid impermeable bottom including at least one concave surface, wherein at least a portion of the bottom is transparent, wherein at least a portion of the bottom includes a low-adhesion or no-adhesion material in or on the at least one concave surface, and wherein the gas permeable, liquid impermeable bottom includes polystyrene.
-
Patent Agency Ranking
公开(公告)号：US20240263121A1
公开(公告)日：2024-08-08
申请号：US18635480
申请日：2024-04-15
Applicant: CORNING INCORPORATED
Inventor： Gregory Roger Martin , Allison Jean Tanner
Abstract: A cell culture insert for use in culturing cells to promote the formation of spheroids and methods of using these spheroid-promoting cell culture inserts. The cell culture insert includes a porous membrane and one or more sidewalls that are non-adherent to cells and cause the cells in the insert to associate with each other and form spheroids.
-
公开(公告)号：US11905506B2
公开(公告)日：2024-02-20
申请号：US17591747
申请日：2022-02-03
Applicant: CORNING INCORPORATED
Inventor： Gregory Roger Martin , Allison Jean Tanner
CPC classification number: C12M23/08 , C12M23/04 , C12M23/24 , C12M23/34 , C12M23/38 , C12M23/58 , C12M25/02 , C12M25/04 , C12M25/06 , C12M29/04 , C12M41/00 , C12N5/0602
Abstract: A multilayered cell culture apparatus for the culturing of cells is disclosed. The cell culture apparatus is defined as an integral structure having a plurality of cell culture chambers in combination with tracheal space(s). The body of the apparatus has imparted therein gas permeable membranes in combination with tracheal spaces that will allow the free flow of gases between the cell culture chambers and the external environment. The flask body also includes an aperture that will allow access to the cell growth chambers by means of a needle or cannula. The size of the apparatus, and location of an optional neck and cap section, allows for its manipulation by standard automated assay equipment, further making the apparatus ideal for high throughput applications.
-
公开(公告)号：US11866683B2
公开(公告)日：2024-01-09
申请号：US16758066
申请日：2018-11-05
Applicant: CORNING INCORPORATED
Inventor： Gregory Roger Martin , Allison Jean Tanner
Abstract: A cell culture apparatus includes a cell culture module including multiple cell culture chambers. A manifold connects the multiple cell culture chambers together along a side of the cell culture module. The manifold includes a side wall base structure connected to the side of the cell culture module and a column structure that is formed as a monolithic part of the side wall base structure. The column structure defines a fluid flow pathway through the manifold and to inlets to the cell culture chambers to allow filling and emptying of the cell culture chambers of liquid medium.
-
公开(公告)号：US20230357686A1
公开(公告)日：2023-11-09
申请号：US18219266
申请日：2023-07-07
Applicant: CORNING INCORPORATED
Inventor： William Joseph Lacey , Gregory Roger Martin , Allison Jean Tanner
Abstract: A cell culture vessel includes a vessel body, support columns, and a stabilizer device. The vessel body defines a cell culture chamber enclosed between a bottom wall and a top wall. The support column is within the cell culture chamber and extends between the top wall and the bottom wall. The stabilizer device covers a width and length of the cell culture chamber and has a column engaging structure that is sized to slidingly engage the support column such that the stabilizer device is movable along the support column as a liquid culture medium is received in the cell culture chamber. The support column guides the stabilizer device along a length of the support column as the stabilizer device rises with rising liquid level in the cell culture chamber during a liquid culture medium filling operation.
-
公开(公告)号：US11768194B2
公开(公告)日：2023-09-26
申请号：US17564465
申请日：2021-12-29
Applicant: CORNING INCORPORATED
Inventor： Joshua Monroe Cobb , Gregory Roger Martin , Robert Raymond Raczkowski , Mark Christian Sanson , Horst Schreiber , Todd Michael Upton
CPC classification number: G01N33/4833 , C12M23/12 , C12M41/46 , G01N21/55 , G01N33/5005 , G02B21/361 , G02B21/002 , G02B21/04 , G02B21/36
Abstract: A cell monitoring plate comprises a flat surface on which multiple cell culturing vessels may be stacked. The flats surface has multiple optical imaging systems embedded therein to fully image a cell culture vessels stacked on the plate. Each one of the multiple optical imaging systems provides both illumination and imaging through a single aperture in the surface of the monitoring plate.
-
-
-
-
-
-
-
-
-
Search Results
87
records
(took 0.017 seconds)
