公开(公告)号：US09763585B2

公开(公告)日：2017-09-19

申请号：US14258141

申请日：2014-04-22

Applicant: COVIDIEN LP

Inventor： Paul Stanley Addison ,  Rui Wang ,  Scott McGonigle ,  James N. Watson

IPC: A61B5/02 ,  A61B5/0295 ,  A61B5/022 ,  A61B5/08 ,  A61B5/1455

CPC classification number: A61B5/0295 ,  A61B5/022 ,  A61B5/0816 ,  A61B5/14551

Abstract: The present invention relates to physiological signal processing, and in particular to methods and systems for processing physiological signals to predict a fluid responsiveness of a patient. A medical monitor for monitoring a patient includes an input receiving a photoplethysmograph (PPG) signal representing light absorption by a patient's tissue. The monitor also includes a perfusion status indicator indicating a perfusion status of the PPG signal, and a fluid responsiveness predictor (FRP) calculator programmed to calculate an FRP value based on a respiratory variation of the PPG signal. The FRP calculator applies a correction factor based on the perfusion status indicator.

公开(公告)号：US09554712B2

公开(公告)日：2017-01-31

申请号：US13779487

申请日：2013-02-27

Applicant: Covidien LP

Inventor： Braddon M. Van Slyke ,  Ronald Kadlec ,  Scott McGonigle ,  Michael Mestek ,  Paul Stanley Addison ,  James Nicholas Watson

IPC: A61B5/024 ,  A61B5/1455 ,  A61B5/1495 ,  A61B5/00 ,  A61B5/0205

CPC classification number: A61B5/02416 ,  A61B5/0205 ,  A61B5/14551 ,  A61B5/1495 ,  A61B5/7278

Abstract: A test unit may generate a pulse signal based on a pulsatile profile and a frequency modulation component of a respiratory profile. A respiration modulated signal may be generated from the pulse signal, an amplitude modulation component, and a baseline modulation component. A patient modulated signal may be generated based on the respiration modulated signal and a patient profile. The artificial PPG signal may be generated based on the patient modulated signal and an artifact profile. The artificial PPG signal may be output to an electronic device.

Abstract translation: 测试单元可以基于脉动轮廓和呼吸轮廓的频率调制分量产生脉冲信号。 可以从脉冲信号，幅度调制分量和基线调制分量产生呼吸调制信号。 可以基于呼吸调制信号和患者轮廓来产生患者调制信号。 人造PPG信号可以基于患者调制信号和伪像分布生成。 可以将人造PPG信号输出到电子设备。

公开(公告)号：US09462976B2

公开(公告)日：2016-10-11

申请号：US14572461

申请日：2014-12-16

Applicant: Covidien LP

Inventor： Paul Stanley Addison ,  James Nicholas Watson

IPC: G01B11/14 ,  A61B5/00 ,  A61B5/06 ,  A61B5/1455

CPC classification number: A61B5/6843 ,  A61B5/0059 ,  A61B5/061 ,  A61B5/1455 ,  A61B5/14552 ,  A61B5/4887 ,  A61B5/6814 ,  A61B5/6815 ,  A61B5/6822 ,  A61B5/6824 ,  A61B5/6826 ,  A61B5/6829 ,  A61B5/684 ,  A61B5/6844 ,  A61B5/7203 ,  A61B5/7221 ,  A61B2562/0233 ,  G01B11/14

Abstract: A physiological monitoring system may determine a probe-off condition. A physiological sensor may be used to emit one or more wavelengths of light. A received light signal may be processed to obtain a light signal corresponding to the emitted light and an ambient signal. The signals may be analyzed to identify similar behavior. The system may determine whether the physiological sensor is properly positioned based on the analysis.

Abstract translation: 生理监测系统可以确定探测条件。 可以使用生理传感器来发射一个或多个波长的光。 可以处理接收的光信号以获得对应于所发射的光和环境信号的光信号。 可以分析信号以识别类似的行为。 该系统可以基于分析来确定生理传感器是否正确定位。

公开(公告)号：US20150208964A1

公开(公告)日：2015-07-30

申请号：US14599896

申请日：2015-01-19

Applicant: Covidien LP

Inventor： Paul Stanley Addison ,  James Nicholas Watson

IPC: A61B5/1455 ,  A61B5/00 ,  A61B5/0205

CPC classification number: A61B5/14551 ,  A61B5/0816 ,  A61B5/7221

Abstract: Systems and methods are provided for determining respiration information. Respiration information is determined from physiological signals responsive to regional oxygen saturation information. Respiration information is determined based on any of the amplitude, frequency, or baseline components of the physiological signals.

Abstract translation: 提供用于确定呼吸信息的系统和方法。 响应于区域氧饱和度信息的生理信号确定呼吸信息。 基于生理信号的幅度，频率或基线分量中的任何一个确定呼吸信息。

公开(公告)号：US08922788B2

公开(公告)日：2014-12-30

申请号：US13726075

申请日：2012-12-22

Applicant: Covidien LP

Inventor： Paul Stanley Addison ,  James Nicholas Watson

IPC: G01B11/14 ,  A61B5/06 ,  A61B5/00 ,  A61B5/1455

CPC classification number: A61B5/6843 ,  A61B5/0059 ,  A61B5/061 ,  A61B5/1455 ,  A61B5/14552 ,  A61B5/4887 ,  A61B5/6814 ,  A61B5/6815 ,  A61B5/6822 ,  A61B5/6824 ,  A61B5/6826 ,  A61B5/6829 ,  A61B5/684 ,  A61B5/6844 ,  A61B5/7203 ,  A61B5/7221 ,  A61B2562/0233 ,  G01B11/14

Abstract: A physiological monitoring system may determine a probe-off condition. A physiological sensor may be used to emit one or more wavelengths of light. A received light signal may be processed to obtain a light signal corresponding to the emitted light and an ambient signal. The signals may be analyzed to identify similar behavior. The system may determine whether the physiological sensor is properly positioned based on the analysis.

Abstract translation: 生理监测系统可以确定探测条件。 可以使用生理传感器来发射一个或多个波长的光。 可以处理接收的光信号以获得对应于所发射的光和环境信号的光信号。 可以分析信号以识别类似的行为。 该系统可以基于分析来确定生理传感器是否正确定位。

公开(公告)号：US20140316278A1

公开(公告)日：2014-10-23

申请号：US14259812

申请日：2014-04-23

Applicant: COVIDIEN LP

Inventor： Paul Stanley Addison ,  Rui Wang ,  Scott McGonigle ,  James N. Watson

IPC: A61B5/00

CPC classification number: A61B5/02416 ,  A61B5/0816 ,  A61B5/4848 ,  A61B5/7278

Abstract: The present invention relates to physiological signal processing, and in particular to methods and systems for processing physiological signals to predict a fluid responsiveness of a patient. A medical monitor for monitoring a patient may include an input receiving a photoplethysmograph (PPG) signal representing light absorption by a patient's tissue, and a fluid responsiveness predictor (FRP) calculator programmed to calculate an FRP metric. The monitor also may include a memory storing a relationship between the FRP metric and a pulse pressure variation (PPV) metric. The FRP metric is calculated based on a respiratory variation of the PPG signal and based on the relationship.

Abstract translation: 本发明涉及生理信号处理，特别涉及用于处理生理信号以预测患者的流体反应性的方法和系统。 用于监测患者的医疗监视器可以包括接收表示患者组织的光吸收的光电容积描记器（PPG）信号的输入端和被编程为计算FRP度量的流体响应性预测器（FRP）计算器。 监视器还可以包括存储FRP度量和脉冲压力变化（PPV）度量之间的关系的存储器。 基于PPG信号的呼吸变化并根据关系计算FRP度量。

公开(公告)号：US20140275889A1

公开(公告)日：2014-09-18

申请号：US13841387

申请日：2013-03-15

Applicant: Covidien LP

Inventor： Paul Stanley Addison ,  James Watson

IPC: A61B5/00 ,  A61B5/1455 ,  A61B5/0205

CPC classification number: A61B5/14551 ,  A61B5/0075 ,  A61B5/02416 ,  A61B5/0816 ,  A61B5/7207 ,  A61B2560/0223 ,  A61B2562/08 ,  A61B2562/085

Abstract: A physiological monitoring system may determine respiration information from a PPG signal. The system may analyze the PPG signal with respect to itself by associating values of the PPG signal with values of a time-delayed version of the PPG signal to create pairs of associated values. A subset of associated values may be identified. Respiration metric values may be determined based on the subset of pairs. The respiration metric values may be amplitude values and/or time values corresponding to the subset of pairs. The respiration metric values may be analyzed using autocorrelation, cross-correlation, or other signal processing techniques to determine respiration information such as respiration rate.

Abstract translation: 生理监测系统可以从PPG信号确定呼吸信息。 该系统可以通过将PPG信号的值与PPG信号的时间延迟版本的值相关联以产生对相关联的值来分析其自身的PPG信号。 可以识别相关联的值的子集。 可以基于对的子集来确定呼吸度量值。 呼吸度量值可以是对应于对的子集的振幅值和/或时间值。 可以使用自相关，互相关或其他信号处理技术来分析呼吸度量值，以确定呼吸信息，例如呼吸速率。

公开(公告)号：US20140243633A1

公开(公告)日：2014-08-28

申请号：US13776686

申请日：2013-02-25

Applicant: COVIDIEN LP

Inventor： Paul Stanley Addison ,  James Nicholas Watson

IPC: A61B5/1455

CPC classification number: A61B5/14552 ,  A61B5/6844 ,  A61B5/7221

Abstract: A physiological monitoring system may determine a probe-off condition. A physiological sensor may receive a light signal including one or more wavelengths of light. The received light signal may be processed to obtain a light signal corresponding to an ambient light signal and a light signal corresponding to an emitted light signal and the ambient light signal. The signals may be analyzed to identify an inverse effect. The system may determine whether the physiological sensor is properly positioned based on the identification of an inverse effect.

Abstract translation: 生理监测系统可以确定探测条件。 生理传感器可以接收包括一个或多个波长的光的光信号。 可以处理所接收的光信号以获得对应于环境光信号的光信号和对应于发出的光信号和环境光信号的光信号。 可以分析信号以识别逆效应。 该系统可以基于反效应的识别来确定生理传感器是否正确定位。

公开(公告)号：US20140180043A1

公开(公告)日：2014-06-26

申请号：US13726071

申请日：2012-12-22

Applicant: COVIDIEN LP

Inventor： Paul Stanley Addison ,  James Nicholas Watson

IPC: A61B5/1455

CPC classification number: A61B5/14551 ,  A61B5/02416 ,  A61B5/7221

Abstract: A physiological monitoring system may use photonic signals at one or more wavelengths to determine physiological parameters. The system may monitor a photoplethysmograph (PPG) signal, which may include a periodic component, and an aperiodic component. An attractor may be generated based on a first segment of the PPG signal and a second segment of the PPG signal shifted in time relative to the first segment by a time delay. The system may analyze points of the attractor that correspond to a curve, analyze the distribution of the attractor about a curve, or both, to determine a signal quality metric indicative of cycle to cycle variation in the PPG signal.

Abstract translation: 生理监测系统可以使用一个或多个波长的光子信号来确定生理参数。 该系统可以监测可以包括周期性成分和非周期性成分的光电容积描记器（PPG）信号。 可以基于PPG信号的第一片段和PPG信号的第二片段相对于第一片段在时间上移位时间延迟来产生吸引子。 系统可以分析对应于曲线的吸引子的点，分析关于曲线或两者的吸引子的分布，以确定指示PPG信号中的周期与周期变化的信号质量度量。