公开(公告)号：US5847968A

公开(公告)日：1998-12-08

申请号：US605540

申请日：1996-02-16

Applicant: Shinji Miura ,  Masayuki Tsuchida ,  Hirokazu Uemura ,  Hiroyuki Yoshimura ,  Yuichi Nishimura

Inventor： Shinji Miura ,  Masayuki Tsuchida ,  Hirokazu Uemura ,  Hiroyuki Yoshimura ,  Yuichi Nishimura

IPC: G06F17/50 ,  H05K13/08 ,  H02B1/24

CPC classification number: G06F17/5068

Abstract: When a component is placed on a circuit board, a placement position is determined by method of elastic center. Then, it is determined whether the component was placed on the circuit board. After that, connectors are routed between the component and a design candidate component which is already placed. After that, the next component is set, and the above mentioned packaging processing is repeated.

Abstract translation: 当组件放置在电路板上时，通过弹性中心的方法确定放置位置。 然后，确定组件是否放置在电路板上。 之后，连接器在组件和已经放置的设计候选组件之间布线。 之后，设定下一个部件，重复上述的包装处理。

公开(公告)号：US5631402A

公开(公告)日：1997-05-20

申请号：US488430

申请日：1995-06-07

Applicant: Shuhei Miyazawa ,  Shigeki Hibi ,  Hiroyuki Yoshimura ,  Takashi Mori ,  Yorihisa Hoshino ,  Mitsuo Nagai ,  Kouichi Kikuchi ,  Hisashi Shibata ,  Kazuo Hirota ,  Takashi Yamanaka ,  Isao Yamatsu ,  Masanori Mizuno

Inventor： Shuhei Miyazawa ,  Shigeki Hibi ,  Hiroyuki Yoshimura ,  Takashi Mori ,  Yorihisa Hoshino ,  Mitsuo Nagai ,  Kouichi Kikuchi ,  Hisashi Shibata ,  Kazuo Hirota ,  Takashi Yamanaka ,  Isao Yamatsu ,  Masanori Mizuno

IPC: A61K31/46 ,  A61P1/00 ,  A61P1/08 ,  A61P25/20 ,  A61P43/00 ,  C07C229/60 ,  C07C229/64 ,  C07D451/04 ,  C07D451/12 ,  C07C229/40 ,  C07C229/52

CPC classification number: C07D451/04

Abstract: An aminobenzoic acid derivative represented by the following general formulas (I), (I-2) or (I-3), or a pharmacologically acceptable salt thereof, which exhibits a serotonin antagonism and an acetylcholine release accelerating activity at a well-balanced activity ratio and which is efficacious as a drug for patients with gastrointestinal unindentified complaints: ##STR1## wherein R.sup.1 represents a group such as an alkynyl or cyanoalkyl group; R.sup.2 represents a group such as an amino or acylamino group; R.sup.3 represents a halogen atom; X represents --O-- or --NH--; and A represents an oxygen or sulfur atom.

Abstract translation: 由以下通式（I），（I-2）或（I-3）表示的氨基苯甲酸衍生物或其药理学上可接受的盐，其平衡活性显示出5-羟色胺拮抗作用和乙酰胆碱释放促进活性 （I-2）和（IMA）（I-3），其中R1表示诸如炔基或氰基烷基的基团 ; R2表示氨基或酰氨基等基团。 R3表示卤原子; X表示-O-或-NH-; A表示氧或硫原子。

公开(公告)号：US5064848A

公开(公告)日：1991-11-12

申请号：US518816

申请日：1990-05-04

Applicant: Youji Yamagishi ,  Kozo Akasaka ,  Takeshi Suzuki ,  Mitsuaki Miyamoto ,  Kouji Nakamoto ,  Kazuo Okano ,  Shinya Abe ,  Hironori Ikuta ,  Kenji Hayashi ,  Hiroyuki Yoshimura ,  Tohru Fujimori ,  Koukichi Harada ,  Isao Yamatsu

Inventor： Youji Yamagishi ,  Kozo Akasaka ,  Takeshi Suzuki ,  Mitsuaki Miyamoto ,  Kouji Nakamoto ,  Kazuo Okano ,  Shinya Abe ,  Hironori Ikuta ,  Kenji Hayashi ,  Hiroyuki Yoshimura ,  Tohru Fujimori ,  Koukichi Harada ,  Isao Yamatsu

IPC: C07C57/42 ,  A61K31/15 ,  A61K31/165 ,  A61K31/18 ,  A61K31/19 ,  A61K31/215 ,  A61K31/22 ,  A61K31/275 ,  A61K31/277 ,  A61K31/33 ,  A61P7/02 ,  A61P9/08 ,  A61P9/10 ,  C07C51/00 ,  C07C59/64 ,  C07C67/00 ,  C07C69/618 ,  C07C231/00 ,  C07C231/02 ,  C07C233/01 ,  C07C233/02 ,  C07C233/11 ,  C07C235/14 ,  C07C235/34 ,  C07C237/20 ,  C07C239/00 ,  C07C241/00 ,  C07C251/40 ,  C07C251/60 ,  C07C253/00 ,  C07C253/30 ,  C07C255/04 ,  C07C255/32 ,  C07C255/34 ,  C07C255/37 ,  C07C255/41 ,  C07C255/61 ,  C07C255/62 ,  C07C257/04 ,  C07C257/06 ,  C07C257/10 ,  C07C257/18 ,  C07C301/00 ,  C07C303/38 ,  C07C311/00 ,  C07C311/13 ,  C07C311/15 ,  C07C311/17 ,  C07C325/00 ,  C07C327/00 ,  C07C327/58 ,  C07D207/46 ,  C07D213/40 ,  C07D213/72 ,  C07D213/75 ,  C07D249/12 ,  C07D257/04 ,  C07D339/08 ,  C07D521/00

CPC classification number: C07D257/04 ,  C07C235/14 ,  C07C235/34 ,  C07C251/40 ,  C07C251/60 ,  C07C255/00 ,  C07C255/41 ,  C07C255/62 ,  C07C257/06 ,  C07C257/18 ,  C07C311/13 ,  C07C311/17 ,  C07C327/58 ,  C07C59/64 ,  C07D207/46 ,  C07D213/40 ,  C07D213/75 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D339/08

Abstract: A new diphenyl-methane derivative is useful to inhibit agglomeration of blood and is defined by the formula, including a diphenylethylene derivative and a benzophenone oxime ether derivative. ##STR1## in which R1 and R2 each are hydrogen, hydroxyl or a lower alkoxy, U is .dbd.CXY or .dbd.N--O--W,X is hydrogen, cyano or --COR6, R6 being hydroxyl or an amino, Y is --R10--COOR3, R3 being hydrogen or a lower alkoxy, R10 being an alkylene having 1 to 3 carbon atoms, straight or branched, --CO--NR4R5, R4 and R5 each being hydrogen, a lower alkyl or a lower arylalkyl, --CH2--NHSO2--C6H5 or --C(R8).dbd.NR7, R7 being a lower alkoxy or an aryl, R8 is --VR9, V being oxygen, sulfur or nitrogen, R9 being an alkyl or an aryl,W is --CH2--CO--CH2--COOR13, R13 being hydrogen or a lower alkyl, --CH2--C(.dbd.NOR14)--CH2--COOR15, R15 being hydrogen or a lower alkyl, R14 being a lower alkyl, --CH(CN)--(CH2)q--COOR16, R16 being hydrogen or a lower alkyl, q being an integer of 1 to 3, or --(CH2)p--Z, Z being --SH, --SCN or a monovalent group derived from a five- or six-membered ring which may be substituted by a ring having one or more sulfur atoms in the ring, p being 1 or 2.

Abstract translation: 二苯基甲烷衍生物。 式（I）为新的（其中R 1和R 2各自为H，OH或低级烷氧基; U = -C XY或= NOW; X = H，CN或-COR 6; R 6 = OH或NH 2; Y = COOR 3，-CONR 4 R 5，-CH 2 NHSO 2 -C 6 H 5或-C（R 8）= NR 7; R 3 = H或低级烷氧基; R 10 =支链1-3C亚烷基; R 4和R 5各自为H，低级烷基或低级芳基烷基; 低级烷氧基或芳基; R8 = -VR9; V = O，S或N; R9 =烷基或芳基; W = -CH2-CO-CH2-COOR13，-CH2-C（= NOR14）-CH2-COOR15，-CH （CN） - （CH 2）q -COOR 16或 - （CH 2）pZ; R 13 = H或低级烷基; R 14 =低级烷基; R 15 = H或低级烷基; R 16 = H或低级烷基; q = = -SH，-SCN或衍生自5-或6-元环选择的单价gp，通过环中具有1个或更多个S的环; p = 1或2。

公开(公告)号：US4954523A

公开(公告)日：1990-09-04

申请号：US364712

申请日：1989-06-09

Applicant: Youji Yamagishi ,  Kozo Akasaka ,  Takeshi Suzuki ,  Mitsuaki Miyamoto ,  Kouji Nakamoto ,  Kazuo Okano ,  Shinya Abe ,  Hironori Ikuta ,  Kenji Hayashi ,  Hiroyuki Yoshimura ,  Tohru Fujimori ,  Koukichi Harada ,  Isao Yamatsu

Inventor： Youji Yamagishi ,  Kozo Akasaka ,  Takeshi Suzuki ,  Mitsuaki Miyamoto ,  Kouji Nakamoto ,  Kazuo Okano ,  Shinya Abe ,  Hironori Ikuta ,  Kenji Hayashi ,  Hiroyuki Yoshimura ,  Tohru Fujimori ,  Koukichi Harada ,  Isao Yamatsu

IPC: C07C57/42 ,  A61K31/15 ,  A61K31/165 ,  A61K31/18 ,  A61K31/19 ,  A61K31/215 ,  A61K31/22 ,  A61K31/275 ,  A61K31/277 ,  A61K31/33 ,  A61P7/02 ,  A61P9/08 ,  A61P9/10 ,  C07C51/00 ,  C07C59/64 ,  C07C67/00 ,  C07C69/618 ,  C07C231/00 ,  C07C231/02 ,  C07C233/01 ,  C07C233/02 ,  C07C233/11 ,  C07C235/14 ,  C07C235/34 ,  C07C237/20 ,  C07C239/00 ,  C07C241/00 ,  C07C251/40 ,  C07C251/60 ,  C07C253/00 ,  C07C253/30 ,  C07C255/04 ,  C07C255/32 ,  C07C255/34 ,  C07C255/37 ,  C07C255/41 ,  C07C255/61 ,  C07C255/62 ,  C07C257/04 ,  C07C257/06 ,  C07C257/10 ,  C07C257/18 ,  C07C301/00 ,  C07C303/38 ,  C07C311/00 ,  C07C311/13 ,  C07C311/15 ,  C07C311/17 ,  C07C325/00 ,  C07C327/00 ,  C07C327/58 ,  C07D207/46 ,  C07D213/40 ,  C07D213/72 ,  C07D213/75 ,  C07D249/12 ,  C07D257/04 ,  C07D339/08 ,  C07D521/00

CPC classification number: C07D257/04 ,  C07C235/14 ,  C07C235/34 ,  C07C251/40 ,  C07C251/60 ,  C07C255/00 ,  C07C255/41 ,  C07C255/62 ,  C07C257/06 ,  C07C257/18 ,  C07C311/13 ,  C07C311/17 ,  C07C327/58 ,  C07C59/64 ,  C07D207/46 ,  C07D213/40 ,  C07D213/75 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D339/08

Abstract: A new diphenyl-methane derivative is useful to inhibit agglomeration of blood and is defined by the formula, including a diphenylethylene derivative and a benzophenone oxime ether derivative. ##STR1## in which R1 and R2 each are hydrogen, hydroxyl or a lower alkoxy, U is .dbd.CXY or .dbd.N--O--W,X is hydrogen, cyano or --COR6, R6 being hydroxyl or an amino, Y is --R10--COOR3, R3 being hydrogen or a lower alkoxy, R10 being an alkylene having 1 to 3 carbon atoms, straight or branched, --CO--NR4R5, R4 and R5 each being hydrogen, a lower alkyl or a lower aralalkyl, --CH2--NHSO3--C6H5 or --C(R8).dbd.NR7, R7 being a lower alkoxy or an aryl, R8 is --VR9, V being oxygen, sulfur or nitrogen, R9 being an alkyl or an aryl,W is --CH2--CO--CH2--COOR13, R13 being hydrogen or a lower alkyl, --CH2--C(.dbd.NOR14)--CH2--COOR15, R15 being hydrogen or a lower alkyl, R14 being a lower alkyl, --CH(CN)--(CH2)q--COOR16, R16 being hydrogen or a lower alkyl, q being an integer of 1 to 3, or --(CH2)p--Z, Z being --SH, --SCN or a monovalent group derived from a five- or six-membered ring which may be substituted by a ring having one or more sulfur atoms in the ring, p being 1 or 2.

Abstract translation: 二苯基甲烷衍生物。 式（I）为新的（其中R 1和R 2各自为H，OH或低级烷氧基; U = -C XY或= NOW; X = H，CN或-COR 6; R 6 = OH或NH 2; Y = COOR 3，-CONR 4 R 5，-CH 2 NHSO 2 -C 6 H 5或-C（R 8）= NR 7; R 3 = H或低级烷氧基; R 10 =支链1-3C亚烷基; R 4和R 5各自为H，低级烷基或低级芳基烷基; 低级烷氧基或芳基; R8 = -VR9; V = O，S或N; R9 =烷基或芳基; W = -CH2-CO-CH2-COOR13，-CH2-C（= NOR14）-CH2-COOR15，-CH （CN） - （CH 2）q -COOR 16或 - （CH 2）pZ; R 13 = H或低级烷基; R 14 =低级烷基; R 15 = H或低级烷基; R 16 = H或低级烷基; q = = -SH，-SCN或衍生自5-或6-元环选择的单价gp，通过环中具有1个或更多个S的环; p = 1或2。

公开(公告)号：US08991381B2

公开(公告)日：2015-03-31

申请号：US13576738

申请日：2010-02-08

Applicant: Jun Ohya ,  Tatsumi Hamasaki ,  Hiroyuki Yoshimura ,  Masaru Fukuman

Inventor： Jun Ohya ,  Tatsumi Hamasaki ,  Hiroyuki Yoshimura ,  Masaru Fukuman

IPC: B28D5/04 ,  B23D57/00 ,  B24B27/06

CPC classification number: B28D5/045 ,  B23D57/0069 ,  B24B27/0633

Abstract: The present invention provides a method of cutting a workpiece efficiently with high accuracy by utilizing tension adjusters to approximate tension in a wire in a wire saw to a predetermined target tension while effectively reducing only tension in a winder-side wire. The method comprises a forward-driven cutting step of cutting a workpiece while moving a wire forward, a first switching step of reversing a driving direction of the wire, a backward-driven cutting step of cutting the workpiece while moving the wire backward, and a second switching step of reversing a driving direction of the wire and returning to the forward-driven cutting step, the steps being repeated in this order. In both switching steps, only tension in a winder-side wire is reduced by tension manipulators. A reduction in target wire tension therefor is performed after completion of deceleration of the wire in each switching step.

Abstract translation: 本发明提供了一种通过利用张力调节器来有效地切割工件的方法，以使线锯中的线材的张力近似到预定的目标张力，同时有效地仅减小缠绕器线材中的张力。 该方法包括：向前驱动切割步骤，在向前移动线的同时切割工件;反转线的驱动方向的第一切换步骤;向后移动切割工件的向后驱动切割步骤;以及 第二切换步骤，其使线的驱动方向反转并返回到前进驱动的切割步骤，按顺序重复该步骤。 在两个切换步骤中，仅通过张力操纵器减小卷绕机侧线中的张力。 在每个切换步骤中线材的减速完成之后，执行目标线张力的降低。

公开(公告)号：US08881716B2

公开(公告)日：2014-11-11

申请号：US13577051

申请日：2010-02-08

Applicant: Toyohiro Hoshiyama ,  Shoji Imakurusu ,  Hiroyuki Yoshimura ,  Tatsumi Hamasaki

Inventor： Toyohiro Hoshiyama ,  Shoji Imakurusu ,  Hiroyuki Yoshimura ,  Tatsumi Hamasaki

IPC: B23D57/00 ,  B24B27/06 ,  B28D5/04

CPC classification number: B26B27/002 ,  B23D57/0023 ,  B23D57/0053 ,  B23D57/0069 ,  B24B27/0633 ,  B28D5/045

Abstract: The present invention provides a wire saw which cuts a workpiece using a cutting wire and is capable of adjusting wire tension with high responsiveness. The wire saw includes first and second workpiece cutting units 1A and 1B. Each of the workpiece cutting units 1A and 1B includes a pair of guide rollers 10a and 10b around which a wire W is wound to form a workpiece-cutting wire group. The wire saw further includes a tension detector 18 which detects tension in the wire W between the workpiece cutting units 1A and 1B, and a control device 50. The control device 50 changes a rotational speed of the guide rollers 10a and 10b of at least one of the workpiece cutting units based on the tension detected by the tension detector 18 so as to keep the tension within an acceptable range.

Abstract translation: 本发明提供一种线锯，其使用切割线切割工件，并且能够以高响应性调节线张力。 线锯包括第一和第二工件切割单元1A和1B。 每个工件切割单元1A和1B包括一对引导辊10a和10b，绕线W缠绕在其上以形成工件切割线组。 线锯进一步包括检测工件切割单元1A和1B之间的线W中的张力的张力检测器18和控制装置50.控制装置50将导辊10a和10b的旋转速度改变为至少一个 基于由张力检测器18检测到的张力的工件切割单元，以将张力保持在可接受的范围内。

公开(公告)号：US07170699B2

公开(公告)日：2007-01-30

申请号：US10788424

申请日：2004-03-01

Applicant: Hiroyuki Yoshimura

Inventor： Hiroyuki Yoshimura

IPC: G11B5/86 ,  G11B5/82

CPC classification number: G11B5/865 ,  G11B5/667 ,  G11B5/7315 ,  G11B5/8404 ,  G11B5/86

Abstract: A master disk has an aspect ratio of a width of a groove to a depth thereof to facilitate embedding of a soft magnetic film in the groove for stabilizing magnetic printability. The master disk has at least two differently shaped grooves, in each of which the width of the groove is equal to the width in the sector direction of a servo pattern and the depth is varied. A servo pattern has a width equal to a width of the groove in the sector direction, with the depth of the groove being proportional to the servo pattern width. At least two depths of grooves are provided for embedding magnetic materials on a substrate of the master disk. The depth of the groove for embedding the soft magnetic film is made shallow in a region where the pattern width of the servo pattern is narrow and made deep in a region where the pattern width is wide.

Abstract translation: 母盘具有凹槽的宽度与其深度的纵横比，以便于将软磁膜嵌入凹槽中以稳定磁性印刷性。 主盘具有至少两个不同形状的凹槽，每个凹槽中凹槽的宽度等于伺服图案的扇形方向上的宽度，并且深度是变化的。 伺服图案的宽度等于扇区方向上的槽的宽度，凹槽的深度与伺服图案宽度成比例。 提供至少两个凹槽的深度用于将磁性材料嵌入在主盘的基板上。 用于嵌入软磁膜的凹槽的深度在伺服图案的图案宽度窄并且在图案宽度较宽的区域中变深的区域变浅。

公开(公告)号：US06999259B2

公开(公告)日：2006-02-14

申请号：US10658792

申请日：2003-09-09

Applicant: Hiroyuki Yoshimura

Inventor： Hiroyuki Yoshimura

IPC: G11B5/09

CPC classification number: G11B5/865 ,  G11B5/82

Abstract: Magnetic transfer can be performed with high reliability by shortening the magnetic transit interval of servo address information, that is, a section in which “0” or “1” continues. An area for registering information indicating a start position of data inversion or non-inversion of the servo address information is formed between a servo detection pattern and servo address information of the servo signal. When a continuing data section exceeds a predetermined section in a data sequence of the servo address information, the data at the subsequent portion to the exceeding position are inverted or non-inverted, and the exceeding position is registered as a start position for inversion or non-inversion in the area.

Abstract translation: 通过缩短伺服地址信息的磁性传播间隔，即“0”或“1”继续的部分，可以高可靠性进行磁传递。 在伺服检测模式和伺服信号的伺服地址信息之间形成用于登记指示伺服地址信息的数据反转或不反转的开始位置的信息的区域。 当连续数据部分超过伺服地址信息的数据序列中的预定部分时，超过位置的后续部分的数据被反转或不反相，并且超出位置被登记为用于反转或非转换的起始位置 在该地区的反转。

公开(公告)号：US06420363B1

公开(公告)日：2002-07-16

申请号：US09598420

申请日：2000-06-20

Applicant: Shigeki Hibi ,  Kouichi Kikuchi ,  Hiroyuki Yoshimura ,  Mitsuo Nagai ,  Katsuya Tagami ,  Shinya Abe ,  Ieharu Hishinuma ,  Junichi Nagakawa ,  Norimasa Miyamoto ,  Takayuki Hida ,  Aichi Ogasawara ,  Seiko Higashi ,  Kenji Tai ,  Takashi Yamanaka ,  Makoto Asada

Inventor： Shigeki Hibi ,  Kouichi Kikuchi ,  Hiroyuki Yoshimura ,  Mitsuo Nagai ,  Katsuya Tagami ,  Shinya Abe ,  Ieharu Hishinuma ,  Junichi Nagakawa ,  Norimasa Miyamoto ,  Takayuki Hida ,  Aichi Ogasawara ,  Seiko Higashi ,  Kenji Tai ,  Takashi Yamanaka ,  Makoto Asada

IPC: A61K31535

CPC classification number: C07D213/69 ,  C07C57/03 ,  C07C229/44 ,  C07D209/08 ,  C07D215/12 ,  C07D215/14 ,  C07D215/18 ,  C07D223/16 ,  C07D225/06 ,  C07D231/12 ,  C07D233/16 ,  C07D241/38 ,  C07D241/42 ,  C07D241/46 ,  C07D261/18 ,  C07D263/32 ,  C07D265/36 ,  C07D333/76 ,  C07D405/14 ,  C07D455/04 ,  C07D487/04 ,  C07D495/04 ,  G06F17/30607 ,  Y02P20/55

Abstract: To provide novel compounds relating to retinoid which can substitute for retinoic acid used for preventing and treating several diseases and having antagonism against retinoid. Heterocyclic compounds represented by the general formula (1-I) or physiologically acceptable salts thereof: Z—(CR3═CR2)n—COOR1  (1-I) Compounds represented by the general formula (2-I) or physiologically acceptable salts thereof: The compounds according to the present invention exhibit extremely high ability to bind RARs and are effective for treating various kind of diseases such as abnormality in cornification and rheumatoid arthritis.

Abstract translation: 提供与维甲酸有关的新化合物，其可以代替用于预防和治疗几种疾病并对类视黄醇具有拮抗作用的视黄酸。由通式（1-I）表示的杂环化合物或其生理学上可接受的盐：由通式 （2-I）或其生理上可接受的盐：本发明的化合物显示出极高的结合RAR的能力，并且对于治疗角化和类风湿性关节炎中的异常等各种疾病是有效的。

公开(公告)号：US06358995B1

公开(公告)日：2002-03-19

申请号：US09621889

申请日：2000-07-21

Applicant: Katsuya Tagami ,  Hiroyuki Yoshimura ,  Mitsuo Nagai ,  Shigeki Hibi ,  Kouichi Kikuchi ,  Takashi Sato ,  Makoto Okita ,  Yasushi Okamoto ,  Yumiko Nagasaka ,  Naoki Kobayashi ,  Takayuki Hida ,  Kenji Tai ,  Naoki Tokuhara ,  Seiichi Kobayashi

Inventor： Katsuya Tagami ,  Hiroyuki Yoshimura ,  Mitsuo Nagai ,  Shigeki Hibi ,  Kouichi Kikuchi ,  Takashi Sato ,  Makoto Okita ,  Yasushi Okamoto ,  Yumiko Nagasaka ,  Naoki Kobayashi ,  Takayuki Hida ,  Kenji Tai ,  Naoki Tokuhara ,  Seiichi Kobayashi

IPC: A61K3140

CPC classification number: C07D207/337 ,  C07C69/76 ,  C07C69/94 ,  C07D307/54 ,  C07D333/24 ,  C07D405/04 ,  C07D405/10 ,  C07D405/14 ,  C07D407/04 ,  C07D409/04 ,  C07D409/10 ,  C07D409/14

Abstract: The present invention provides a medicament exhibiting excellent retinoic acid receptor agonism. A Carboxylic acid derivative having a fused ring which is represented by the following formula or a pharmacologically acceptable salt thereof: {wherein the symbol represents a single bond or a double bond; X, Y, Z, P, Q, U, V and W are each a group represented by the formula: —O— or —S—, or a group represented by the formula: [wherein Rk (k: 1 to 8) is hydrogen, halogeno, optionally substituted lower alkyl or the like, with either of R7 and R8 being a group represented by the formula: (wherein A and B are each independently an optionally substituted aromatic hydrocarbon ring or an optionally substituted unsaturated heterocycle; and D is optionally protected carboxyl)]}.

Abstract translation: 本发明提供一种显示出优异的视黄酸受体激动作用的药物。具有下式表示的稠环的羧酸衍生物或其药理学上可接受的盐：{其中符号表示单键或双键; X，Y，Z，P，Q，U，V和W分别是由下式表示的基团：-O-或-S-，或由下式表示的基团：[其中R k（k：1至8） 是氢，卤素，任选取代的低级烷基等，其中R 7和R 8中的任一个是由下式表示的基团：（其中A和B各自独立地是任选取代的芳族烃环或任选取代的不饱和杂环; D 任选保护羧基）]}。