公开(公告)号：US20170015684A1

公开(公告)日：2017-01-19

申请号：US15122118

申请日：2015-01-28

Applicant: STELLA PHARMA CORPORATION ,  OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION

Inventor： Hiroshi TAKENAKA ,  Yoichiro OHTA ,  Yusuke TAGUCHI ,  Sayuri UEDA ,  Yuko ISHINO ,  Tomohiro YOSHIKAWA ,  Hideki NAKASHIMA ,  Kohki UEHARA ,  Mitsunori KIRIHATA

IPC: C07F5/02 ,  C07B59/00 ,  C07C47/55 ,  C07C45/63

CPC classification number: C07F5/025 ,  C07B59/00 ,  C07B59/004 ,  C07B2200/05 ,  C07C45/63 ,  C07C47/55

Abstract: 18F-labeled 4-boronophenylalanine (BPA) can be produced by preparing and further processing a precursor of 18F-labeled BPA represented by the following formula: in which R1 represents a bromo group, an iodo group, a fluoro group, a diazaborinane derivative, BX3− or BX3−M+ (wherein X represents a halogen atom; and M+ represents a monovalent monoatomic cation, a polyatomic cation or a complex cation).

Abstract translation: 本发明的目的是提供：一种制备18 F-标记的4-硼苯丙氨酸（BPA）的新方法; 和18 F标记的BPA的前体。 可以通过制备由式（1）表示的化合物并使用该化合物来制备18 F-标记的BPA。 式中，R1表示溴基，碘基，氟原子，二氮杂硼烷衍生物，BX3-或BX3-M +（式中，X表示卤素原子，M +表示一价单原子阳离子，多原子阳离子或络合物 阳离子）。

公开(公告)号：US20160319394A1

公开(公告)日：2016-11-03

申请号：US15108406

申请日：2014-12-28

Applicant: OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION

Inventor： Yasuhiro Konishi ,  Norizo Saito ,  Masao Kishida

IPC: C22B3/18 ,  C22B3/00 ,  C12R1/865

CPC classification number: C22B3/18 ,  C12N1/16 ,  C12P3/00 ,  C12R1/645 ,  C12R1/865 ,  C22B11/04 ,  Y02P10/234

Abstract: [Problem] To provide a means of using a yeast to recover noble metal ions in reduced form, i.e., as noble metals.[Solution] In a liquid to which an electron donor has preferably been added, Saccharomyces cerevisiae, Zygosaccharomyces rouxii, Schizosaccharomyces pombe or a yeast of the Debaryomyces genus deposited as NITE-BP01780 is brought into contact with metal ions of a noble metal such as gold, palladium and platinum, and the noble metals, being the reduced form of the noble metal ions, are recovered from the recovered yeast.

Abstract translation: [溶液]在优选添加电子给体的液体中，将沉淀的作为NITE-BP01780的酿酒酵母（Saccharomyces cerevisiae），接合酵母（Zygosaccharomyces rouxii），粟酒裂殖酵母（Schizosaccharomyces pombe））或酵母属（Debianomyces属）的酵母与贵金属如金的金属离子 ，钯和铂，并且从回收的酵母中回收作为还原形式的贵金属离子的贵金属。

公开(公告)号：US20160280992A1

公开(公告)日：2016-09-29

申请号：US14901496

申请日：2014-10-21

Applicant: OSAKA PREFECTURE UNIVERSITY Public Corporation ,  YASU MEDICAL IMAGING TECHNOLOGY CO., LTD.

Inventor： Taketoshi KAWAI ,  Fumiaki KUNIMOTO

IPC: C09K11/62 ,  B32B37/10 ,  C09K11/61

CPC classification number: C09K11/628 ,  B32B37/10 ,  B32B2307/416 ,  C09K11/616

Abstract: An additive containing an ion as a luminescence center is added to alkali halide powder as a base material. Mechanical energy for applying an impact force, a shearing force, a shear stress, or a friction force is applied so as to grind or mix the alkali halide powder and the additive. The ion as the luminescence center is doped into the alkali halide as the base material so as to obtain alkali halide-based scintillator powder. With this process, the alkali halide-based scintillator powder can be manufactured at a room temperature in the atmospheric air without any complicated condition control or any process at a high temperature under high vacuum and a large-sized scintillator sheet can be produced.

Abstract translation: 将作为发光中心的离子的添加​​剂作为基材添加到卤化碱粉末中。 施加用于施加冲击力，剪切力，剪切应力或摩擦力的机械能，以研磨或混合碱金属卤化物粉末和添加剂。 将作为发光中心的离子作为基材掺杂到碱金属卤化物中，得到碱金属卤化物系闪烁体粉末。 通过该方法，碱卤化物系闪烁体粉末可以在大气中的室温下制造，无需任何复杂的条件控制，或者在高真空下的高温下进行任何处理，可以制造大尺寸的闪烁体片。

公开(公告)号：US20160268757A1

公开(公告)日：2016-09-15

申请号：US15062681

申请日：2016-03-07

Applicant: FUJIKURA LTD. ,  NIPPON TELEGRAPH AND TELEPHONE CORPORATION ,  OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION

Inventor： Tsukasa Hosokawa ,  Kentaro Ichii ,  Katsuhiro Takenaga ,  Shoichiro Matsuo ,  Hirotaka Ono ,  Makoto Yamada

IPC: H01S3/067 ,  H01S3/094 ,  H01S3/16

CPC classification number: H01S3/06729 ,  G02B6/03611 ,  H01S3/06766 ,  H01S3/0804 ,  H01S3/094003 ,  H01S3/094069 ,  H01S3/09415 ,  H01S3/1608

Abstract: An optical fiber for amplification includes a core having an inner core and an outer core surrounding the outer circumferential surface of the inner core. The relative refractive index difference of the inner core to a cladding is smaller than the relative refractive index difference of the outer core to the cladding. The outer core is entirely doped with erbium. The theoretical cutoff wavelength of an LP11 mode light beam is a wavelength of 1,565 nm or more. The theoretical cutoff wavelength of an LP21 mode light beam is a wavelength of 1,530 nm or less. The theoretical cutoff wavelength of the LP02 mode light beam is a wavelength of 980 nm or less.

Abstract translation: 用于放大的光纤包括具有内芯和围绕内芯的外圆周表面的外芯的芯。 内芯与包层的相对折射率差小于外芯与包层的相对折射率差。 外芯完全掺铒。 LP11模式光束的理论截止波长为1,565nm以上的波长。 LP21模式光束的理论截止波长为1530nm以下的波长。 LP02模式光束的理论截止波长为980nm以下的波长。

公开(公告)号：US20150329564A1

公开(公告)日：2015-11-19

申请号：US14435678

申请日：2013-10-08

Applicant: Stella Pharma Corporation ,  Osaka Prefecture University Public Corporation

Inventor： Hiroshi TAKENAKA ,  Yoichiro OHTA ,  Yusuke TAGUCHI ,  Sayuri UEDA ,  Yuko ISHINO ,  Hideki NAKASHIMA ,  Kohki UEHARA ,  Mitsunori KIRIHATA

IPC: C07F5/02 ,  C07C229/08

CPC classification number: C07F5/025 ,  C07B59/001 ,  C07C229/08 ,  C07C229/36 ,  C07C251/24 ,  C07C271/22 ,  C07F5/027 ,  C07F5/04 ,  Y02P20/55

Abstract: Provided are: a novel chiral 4-boronophenylalanine (BPA) derivative; a method for producing the derivative; and a method for producing 18F-2-fluoro-4-borono-L-phenylalanine (18F-labeled BPA; 18F-BPA) using the derivative. A compound represented by formula (1) is prepared. In the formula, R represents BR3R4, BX3− or BX3−M+ (wherein X represents a halogen atom, and M+ represents a monovalent monoatomic cation, a polyatomic cation or a complex cation); R1 represents a hydrogen atom or a protecting group PG1; R2 represents a hydrogen atom or a protecting group PG2; R3 and R4 independently represent OH, or R3, R4 and B together form a ring that serves as a protecting group; and Y represents a halogen atom, NO2, NH2, Sn(R6)3, N═N—NR7R8, OSO2R9, NR10R11, a substituted or unsubstituted phenyliodo group or a substituted or unsubstituted heterocyclic iodo group. The compound is reacted with a fluorination reagent to prepare 18F-labeled BPA.

Abstract translation: 提供：新型手性4-硼苯丙氨酸（BPA）衍生物; 一种制备衍生物的方法; 以及使用该衍生物制备18F-2-氟-4-硼羟-L-苯丙氨酸（18F标记的BPA; 18F-BPA）的方法。 制备由式（1）表示的化合物。 在该式中，R表示BR 3 R 4，BX 3 - 或BX 3 -M +（其中X表示卤原子，M +表示一价单原子阳离子，多原子阳离子或络合阳离子）。 R1表示氢原子或保护基PG1; R2表示氢原子或保护基PG2; R3和R4独立地表示OH，或R3，R4和B一起形成用作保护基的环; Y表示卤素原子，NO 2，NH 2，Sn（R 6）3，N = N-NR 7 R 8，OSO 2 R 9，NR 10 R 11，取代或未取代的苯基碘基或取代或未取代的杂环碘基。 使化合物与氟化试剂反应以制备18F标记的BPA。

公开(公告)号：US20140144972A1

公开(公告)日：2014-05-29

申请号：US13636176

申请日：2011-02-17

Applicant: OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION ,  ISEL CO., LTD. ,  KINKI UNIVERSITY

Inventor： Takayuki Takasugi ,  Yasuyuki Kaneno ,  Sachio Oki ,  Keishi Kubo ,  Noboru Mochizuki ,  Tomotake Hirata

IPC: B23K20/12

CPC classification number: B23K20/1245 ,  B23K20/1255

Abstract: Provided are a friction processing tool in which a service life of the tool is improved and which can reduce a labor hour for manufacturing and a manufacturing cost, and a friction processing apparatus and a friction processing method using the same. In a friction working tool 20 for softening and processing workpieces W1 and W2 of a metal material by frictional heat generated by being pressed against the workpieces while being rotated, a cylindrical tool body 21 is provided, and a distal end surface of the tool body brought into contact with the workpieces W1 and W2 is formed only by a flat shoulder surface 22. The material of the friction processing tool 20 is made of Ni-based dual multi-phase intermetallic compound alloys.

Abstract translation: 提供了一种摩擦处理工具，其中提高了工具的使用寿命并且可以减少制造时的劳动时间和制造成本，以及使用其的摩擦处理装置和摩擦处理方法。 在用于通过在旋转时被压靠在工件上产生的摩擦热来软化和处理金属材料的工件W1和W2的摩擦加工工具20中，设置有圆柱形的工具主体21，并且工具主体的远端表面带来 与工件W1和W2接触仅由平坦的台肩表面22形成。摩擦处理工具20的材料由Ni基双相金属间化合物合金制成。

公开(公告)号：US20130334053A1

公开(公告)日：2013-12-19

申请号：US13974113

申请日：2013-08-23

Applicant: NITTO BOSEKI CO., LTD. ,  OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION

Inventor： Kazuo KONDO ,  Takeyasu Saito ,  Naoki Okamoto ,  Masaru Bunya ,  Minoru Takeuchi

IPC: C25D5/18

CPC classification number: C25D5/18 ,  C25D3/38 ,  H01L21/2885 ,  H01L21/76861 ,  H01L21/76877 ,  H01L21/76898

Abstract: There is provided a method of well filling copper in a conductivity-rendered non-through hole having an aspect ratio (depth/hole diameter) of 5 or more on a substrate in a short period of time, and the method comprises using an acidic copper plating bath comprising a water-soluble copper salt, sulfuric acid, chlorine ion, a brightener and a copolymer of diallylamines and sulfur dioxide and filling copper in the non-through hole by periodic current reversal copper plating.

Abstract translation: 提供了一种在短时间内在衬底上具有5或更大的纵横比（深度/孔直径）的导电性非贯通孔中充满铜的方法，该方法包括使用酸性铜 包含水溶性铜盐，硫酸，氯离子，增白剂和二烯丙基胺和二氧化硫的共聚物的电镀浴，并通过周期性电流反转铜电镀在非贯通孔中填充铜。