公开(公告)号：US11311378B2

公开(公告)日：2022-04-26

申请号：US16908375

申请日：2020-06-22

Applicant: Edwards Lifesciences Corporation

Inventor： Frederic B. Hodshon ,  Rafael Pintor ,  August R. Yambao ,  Abhishek Gautam ,  Louis A. Campbell ,  Lawrence J. Farhat ,  Tammy Huntley ,  Faisal Kalam ,  Travis Zenyo Oba ,  Qinggang Zeng

IPC: A61F2/24 ,  A61F2/00

Abstract: Packaging for prosthetic heart valves including an assembly for securely retaining a heart valve within a jar and facilitating retrieval therefrom. The assembly includes a packaging sleeve that fits closely within the jar and has a clip structure for securing a valve holder. Contrary to previous designs, in one embodiment the valve holder is directed downward into the jar, and the valve is retained with an inflow end upward. The valve may have flexible leaflets, and a leaflet parting member on the end of the shaft extends through the leaflets and couples with the valve holder. The assembly of the packaging sleeve, valve, and holder can then be removed from the jar and a valve delivery tube connected with the holder, or to the leaflet parting member. The packaging sleeve may be bifurcated into two halves connected at a living hinge to facilitate removal from around the valve/holder subassembly.

公开(公告)号：US20220104940A1

公开(公告)日：2022-04-07

申请号：US17553566

申请日：2021-12-16

Applicant: Edwards Lifesciences Corporation

Inventor： Matthew A. Peterson ,  Seung-Beom Yi ,  Siddharth Vad ,  Travis Zenyo Oba ,  Lauren R. Freschauf ,  Amanda French ,  Yaron Keidar ,  Yuanlong Du ,  Gregory Bak-Boychuk ,  Kevin M. Golemo ,  Alexander H. Cooper

IPC: A61F2/24

Abstract: A prosthesis can be configured to grasp intralumenal tissue when deployed within a body cavity and prevent axial flow of fluid around an exterior of the prosthesis. The prosthesis can include an expandable frame configured to radially expand and contract for deployment within the body cavity and a valve body. The expandable frame can include a frame body and a supplemental frame. The valve body can include a plurality of leaflets and one or more intermediate components. The one or more intermediate components can couple at least a portion of the leaflets to the expandable frame. The prosthesis can include an annular flap positioned around an exterior of the expandable frame.

公开(公告)号：US11185321B2

公开(公告)日：2021-11-30

申请号：US16436829

申请日：2019-06-10

Applicant: Edwards Lifesciences Corporation

Inventor： Travis Zenyo Oba ,  Michael C. Murad ,  Manouchehr A. Miraki ,  Anthony P. Carcia ,  Fabian Daniel Schroeder ,  Raffaele Mazzei ,  Tyler Douglas Smith

IPC: A61B17/04 ,  A61B90/30 ,  A61B1/04 ,  A61B17/00

Abstract: Suture clip deployment devices for applying suture clips to sutures are described. Some embodiments can include a generally tubular main body and a vacuum port located at the distal end, a hollow inner body longitudinally slidable within the main body and extending from the main body at its distal end, and a suture recess located in the generally tubular main body. At least one suture clip configured to frictionally fit on an outer surface of the inner body is deployed during use. Clip deployment can occur after a vacuum source is applied to the device so as to draw the suture into the device. The suture lines can be retrieved through the suture recess, and the device can be actuated so as to deliver the suture clip off the delivery device and onto the suture, locking the suture in place.

公开(公告)号：US20210169646A1

公开(公告)日：2021-06-10

申请号：US17175004

申请日：2021-02-12

Applicant: Edwards Lifesciences Corporation

Inventor： Robert C. Taft ,  Travis Zenyo Oba

IPC: A61F2/24 ,  A61F2/95

Abstract: A crimping system for a prosthetic heart valve comprises a split funnel comprising an elongated annular body having an enlarged insertion end, a narrower outlet end, and a central opening extending along a central longitudinal axis of the split funnel, between the insertion end and the outlet end. The body comprises first and second slots extending axially along opposite sides of the body from the outlet end toward the insertion end, the first and second slots defining first and second split portions of the body extending circumferentially between the first and second slots on opposite sides of the central opening. The crimping device is configured to crimp a prosthetic heart valve moving axially through the central opening from the insertion end to the outlet end while allowing portions of the prosthetic heart valve to protrude through the first and second slots and remain in an expanded configuration.

公开(公告)号：US20200345494A1

公开(公告)日：2020-11-05

申请号：US16934879

申请日：2020-07-21

Applicant: Edwards Lifesciences Corporation

Inventor： Harish Manickam Srinimukesh ,  Travis Zenyo Oba ,  David Robert Landon ,  Glen T. Rabito

IPC: A61F2/24

Abstract: Disclosed herein are embodiments of a delivery system which can be used to recapture and/or reposition a replacement valve, such as a replacement mitral valve, after initial deployment of the valve. Embodiments of the disclosure can use the crimping/tensioning of sutures in order to re-crimp the replacement valve after release, though longitudinal or rotational forces.

公开(公告)号：US10667906B2

公开(公告)日：2020-06-02

申请号：US15880181

申请日：2018-01-25

Applicant: Edwards Lifesciences Corporation

Inventor： Mark Chau ,  Travis Zenyo Oba ,  Tammy Huntley ,  Qinggang Zeng ,  August R. Yambao ,  Rafael Pintor

IPC: A61F2/24

Abstract: A system for expanding a device in a conduit or orifice of a human body includes a balloon member that is movable from a first configuration to a second configuration. External surfaces of the balloon member can collectively have a non-cylindrical cross-section relative to a main axis of the balloon member, such that the external surfaces of the balloon member generally conform to the anatomical shape of the conduit or orifice when the balloon member is in the second configuration.

公开(公告)号：US10507102B2

公开(公告)日：2019-12-17

申请号：US15945878

申请日：2018-04-05

Applicant: Edwards Lifesciences Corporation

Inventor： Mark Chau ,  Marlowe E. Patterson ,  Seung-Beom Yi ,  Stephen C. Geist ,  Travis Zenyo Oba

IPC: A61F2/24

Abstract: A prosthetic apparatus for implantation in a native mitral valve includes a main body for placement within the native mitral annulus. The main body is compressible to a radially compressed state for delivery into the heart and is self-expandable from the compressed state to a radially expanded state for implantation. A valve structure is mounted within a lumen of the main body and preferably forms three leaflets made of pericardium. An atrial sealing member is disposed along an atrial portion of the main body and ventricular anchors are coupled to a ventricular portion of the main body. The atrial sealing member impedes the flow of blood between the main body and the native annulus. The ventricular anchors are positioned outside the main body for capturing native mitral valve leaflets between the main body and the ventricular anchors.

公开(公告)号：US20190328515A1

公开(公告)日：2019-10-31

申请号：US16506886

申请日：2019-07-09

Applicant: Edwards Lifesciences Corporation

Inventor： Matthew A. Peterson ,  Seung-Beom Yi ,  Siddharth Vad ,  Travis Zenyo Oba ,  Lauren R. Freschauf ,  Amanda French ,  Yaron Keidar ,  Yuanlong Du ,  Gregory Bak-Boychuk ,  Kevin M. Golemo ,  Alexander H. Cooper

IPC: A61F2/24

Abstract: A heart valve prosthesis for replacing a native mitral valve includes a self-expanding frame with a plurality of anchoring members disposed along the lower region. A valve body is positioned within the self-expanding frame and includes a plurality of leaflets configured to allow blood flow through the self-expanding frame in only one direction. A skirt surrounds the self-expanding frame and is spaced apart therefrom for contacting surrounding tissue and impeding blood flow around the self-expanding frame. The skirt may be reinforced with wires to help maintain a desired shape. The leaflets in the valve body are preferably connected to the self-expanding frame through one or more intermediate components such that the valve body is spaced radially inwardly from an inner surface of the self-expanding frame.

公开(公告)号：US10441416B2

公开(公告)日：2019-10-15

申请号：US15134172

申请日：2016-04-20

Applicant: Edwards Lifesciences Corporation

Inventor： Travis Zenyo Oba ,  Seung-Beom Yi ,  Lauren R. Freschauf ,  Juan Valencia

IPC: A61F2/24 ,  A61B17/00

Abstract: In one representative embodiment, a prosthetic valve assembly for replacing a native heart valve comprises a radially expandable and compressible support structure, the support structure comprising an annular frame having a lumen extending from an inflow end to an outflow end, the support structure further comprising an annular sealing member extending radially inwardly into the lumen of the frame and having an inner peripheral portion defining an orifice, and a radially expandable and compressible valve component, the valve component comprising an annular frame and a valve structure supported inside of the frame for permitting the flow blood through the valve component in one direction and blocking the flow of blood in the opposite direction, wherein the valve component is configured to expand within the orifice of the sealing member and engage the inner peripheral portion of the sealing member when radially expanded.

公开(公告)号：US20190209048A1

公开(公告)日：2019-07-11

申请号：US16356412

申请日：2019-03-18

Applicant: Edwards Lifesciences Corporation

Inventor： Louis A. Campbell ,  Travis Zenyo Oba ,  Rafael Pintor

IPC: A61B5/107 ,  A61B5/00 ,  A61B90/00 ,  A61F2/24

CPC classification number: A61B5/1076 ,  A61B5/6853 ,  A61B5/6858 ,  A61B5/6885 ,  A61B90/08 ,  A61B2090/061 ,  A61B2090/064 ,  A61B2090/0811 ,  A61F2/2496

Abstract: An orifice-expanding device for measuring an expanded heart valve. The device includes a proximal handle having a shaft and an orifice-expanding device with a hub mounted to a distal end of the shaft and a plurality of arms evenly spaced around the axis and connected to the hub and extending therefrom in a distal direction to distal ends of the arms. The distal end of each arm has an expanding portion with an outer surface, the expanding portions being configured to move radially outward with respect to each other, wherein expansion of the expanding portions causes the distal ends of the arms to flex outward. A pressure-measuring device measures a pressure applied to the aortic valve annulus, and a size-measuring device measures a dimension of the aortic valve annulus after the annulus has been expanded.