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公开(公告)号:US20190134288A1
公开(公告)日:2019-05-09
申请号:US16240831
申请日:2019-01-07
Applicant: Medtronic, Inc.
Inventor: Orhan Soykan , VenKatesh R. Manda , Martin T. Gerber , Christopher M. Hobot
IPC: A61M1/16 , A61B5/0452 , A61B5/145 , A61M1/14 , A61B5/0205 , A61B5/0402
Abstract: A medical monitoring device for monitoring electrical signals from the body of a subject is described. The medical monitoring device monitors electrical signals originating from a cardiac cycle of the subject and associates each cardiac cycle with a time index. The medical monitoring device applies a forward computational procedure to generate a risk score indicative of hyperkalemia, hypokalemia or arrhythmia of the subject. The medical monitoring device can adjust the forward computational procedure based upon clinical data obtained from the subject.
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公开(公告)号:US10245365B2
公开(公告)日:2019-04-02
申请号:US16003245
申请日:2018-06-08
Applicant: Medtronic, Inc.
Inventor: Martin T. Gerber , Christopher M. Hobot
Abstract: An apparatus and method for replenishing urease in a sorbent cartridge for use in sorbent dialysis. The sorbent cartridge is configured to allow an amount of urease to be added to the sorbent cartridge. A urease solution can be injected into the sorbent cartridge to replenish the urease containing module, or solid urease can be added to the sorbent cartridge. The sorbent module can also comprise other, rechargeable, sorbent materials for removing toxins other than urea from spent dialysate.
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公开(公告)号:US10207041B2
公开(公告)日:2019-02-19
申请号:US15263582
申请日:2016-09-13
Applicant: Medtronic, Inc.
Inventor: Orhan Soykan , VenKatesh R. Manda , Martin T. Gerber , Christopher M. Hobot
IPC: A61B5/0205 , A61B5/0452 , A61M1/16 , A61B5/0402 , A61B5/145 , A61M1/14 , A61B5/04 , A61B5/00
Abstract: A medical monitoring device for monitoring electrical signals from the body of a subject is described. The medical monitoring device monitors electrical signals originating from a cardiac cycle of the subject and associates each cardiac cycle with a time index. The medical monitoring device applies a forward computational procedure to generate a risk score indicative of hyperkalemia, hypokalemia or arrhythmia of the subject. The medical monitoring device can adjust the forward computational procedure based upon clinical data obtained from the subject.
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公开(公告)号:US20180361354A1
公开(公告)日:2018-12-20
申请号:US15958337
申请日:2018-04-20
Applicant: Medtronic, Inc.
Inventor: Bryant J. Pudil , Christopher M. Hobot
Abstract: The invention relates to systems and methods for disinfecting, recharging, and conditioning zirconium phosphate in a reusable sorbent module. The systems and methods provide for reuse of a zirconium phosphate sorbent module after dialysis.
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公开(公告)号:US20180289880A1
公开(公告)日:2018-10-11
申请号:US16003245
申请日:2018-06-08
Applicant: Medtronic, Inc.
Inventor: Martin T. Gerber , Christopher M. Hobot
IPC: A61M1/16
CPC classification number: A61M1/1696
Abstract: An apparatus and method for replenishing urease in a sorbent cartridge for use in sorbent dialysis. The sorbent cartridge is configured to allow an amount of urease to be added to the sorbent cartridge. A urease solution can be injected into the sorbent cartridge to replenish the urease containing module, or solid urease can be added to the sorbent cartridge. The sorbent module can also comprise other, rechargeable, sorbent materials for removing toxins other than urea from spent dialysate.
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公开(公告)号:US20180263511A1
公开(公告)日:2018-09-20
申请号:US15547607
申请日:2016-02-02
Applicant: Medtronic, Inc.
Inventor: John Burnes , Rebecca Poindexter , Daniel Bloomberg , Christopher M. Hobot , Roland C. Maude-Griffin
IPC: A61B5/0205 , A61M1/16 , A61B5/00 , A61B5/145 , A61B5/11 , A61B5/0464 , A63B22/02 , A63B24/00 , A61M16/00
Abstract: A system and method for controlling a monitoring mode or treatment mode of an implantable medical device based on the detection of an external signal. The system and related method allow for more frequent monitoring of medical parameters at times where more frequent monitoring is necessary, such as during or after a dialysis session, with less frequent monitoring at other times, allowing for a more efficient medical device. The invention also allows for the frequency or mode of treatment by the implantable medical device, or the transmission of data from the implantable medical device to be controlled based on the external signal.
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公开(公告)号:US20180193546A1
公开(公告)日:2018-07-12
申请号:US15914791
申请日:2018-03-07
Applicant: Medtronic, Inc.
Inventor: Martin T. Gerber , Christopher M. Hobot
CPC classification number: A61M1/28 , A61B5/14507 , A61B5/6866 , A61M1/1601 , A61M1/1609 , A61M1/287 , A61M2205/3306 , A61M2205/3324 , A61M2205/50 , A61M2205/75 , G01N21/78 , G01N21/80 , G01N2021/7773 , G01N2021/7783 , G01N2021/7786 , G01N2800/06
Abstract: The invention relates to a testing system and related methods for detecting peritonitis or infection in peritoneal dialysate removed from a patient. The testing system can include a fluid sensor apparatus in a fluid line of a peritoneal dialysis cycler through which spent peritoneal dialysate can be pumped. The fluid sensor apparatus can detect one or more markers associated with peritonitis or infection.
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公开(公告)号:US10004839B2
公开(公告)日:2018-06-26
申请号:US14722094
申请日:2015-05-26
Applicant: Medtronic, Inc.
Inventor: Bryant J. Pudil , Christopher M. Hobot
CPC classification number: A61M1/1696 , A61M1/14 , B01J20/0292
Abstract: A sorbent cartridge comprising one or more detachable modules. The sorbent cartridge can have one or more modules contained therein having connectors connecting each of the modules. One or more of the modules can be reusable and the sorbent materials therein recharged. The sorbent cartridge can include a module containing an anion exchange resin, such as zirconium oxide, downstream of zirconium phosphate in the sorbent cartridge to recapture phosphate anions that leach out of the zirconium phosphate.
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公开(公告)号:US10004838B2
公开(公告)日:2018-06-26
申请号:US14645389
申请日:2015-03-11
Applicant: Medtronic, Inc.
Inventor: Martin T. Gerber , Christopher M. Hobot
CPC classification number: A61M1/1696 , A61M2205/18 , A61M2205/33 , B01D61/30 , B01D61/32 , B01J20/0211 , B01J20/34
Abstract: A reserve zirconium phosphate module for continuing dialysis in the event the capacity of the original zirconium phosphate module is exceeded. The sorbent cartridge can have a sensor for detecting when the capacity of the zirconium phosphate material has been exceeded, and a valve assembly for diverting the flow of spent dialysate into the reserve module when needed. Any of the modules of the sorbent cartridge can be reusable and the sorbent materials therein recharged.
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公开(公告)号:US09981245B2
公开(公告)日:2018-05-29
申请号:US14722068
申请日:2015-05-26
Applicant: Medtronic, Inc.
Inventor: Bryant J. Pudil , Martin T. Gerber , Christopher M. Hobot
CPC classification number: B01J20/3475 , A61M1/1696 , B01D15/203 , B01J20/06
Abstract: Methods and related apparatuses for sorbent recharging are provided. The methods and related apparatuses for recharging can recharge a specific rechargeable layer of a sorbent material such as zirconium oxide and/or zirconium phosphate in a sorbent cartridge. The methods and apparatuses include passing solutions containing aqueous basic solutions through the zirconium oxide. The apparatus allows for recharging the zirconium oxide, and also for recharging zirconium phosphate, wherein the sorbent materials are contained in reusable sorbent modules.
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