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公开(公告)号:US20210123964A1
公开(公告)日:2021-04-29
申请号:US16662655
申请日:2019-10-24
Applicant: Palo Alto Research Center Incorporated
Inventor: Saman Mostafavi , Hong Yu , Ajay Raghavan , Peter Kiesel
Abstract: A monitoring system includes an array of optical sensors disposed within a transformer tank. Each optical sensor is configured to have an optical output that changes in response to a temperature within the transformer tank. An analyzer is coupled to the array of optical sensors. The analyzer is configured to determine a sensed temperature distribution based on the sensed temperature. The sensed temperature distribution is compared to an expected distribution. Exterior contamination of the transformer tank is detected based on the comparison.
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公开(公告)号:US10890532B2
公开(公告)日:2021-01-12
申请号:US15657607
申请日:2017-07-24
Applicant: Palo Alto Research Center Incorporated
Inventor: Michael I. Recht , Peter Kiesel , Joerg Martini , Francisco E. Torres
Abstract: The disclosure relates to compositions for use in assays, the compositions comprising at least one latent fluorophore including at least one enzyme-reactive quenching group and a conjugative group; and a support connectable to the latent fluorophore by the conjugative group. The disclosure further relates to methods of measuring the presence and/or concentration of an analyte, as well as methods of measuring the relative activity of at least two enzymes.
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公开(公告)号:US10724067B2
公开(公告)日:2020-07-28
申请号:US15960049
申请日:2018-04-23
Applicant: Palo Alto Research Center Incorporated
Inventor: Joerg Martini , Michael Recht , Peter Kiesel
Abstract: One or more live substances is cultured at a plurality of test locations of a test vessel. The test locations include a thermochromic material and one or more test substances. A spectral shift in light emanating from the thermochromic material of the test locations is detected. The spectral shift occurs in response to an increase or decrease in energy conversion by the live substance. An effect of the one or more test substances on the live substances is determined based on the detected spectral shift.
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公开(公告)号:US10324020B2
公开(公告)日:2019-06-18
申请号:US14139317
申请日:2013-12-23
Applicant: Palo Alto Research Center Incorporated
Inventor: David M. Johnson , Noble M. Johnson , Michael I. Recht , Joerg Martini , Tim Curley , Peter Kiesel , Martin Sheridan
Abstract: Embodiments are directed to an apparatus that includes a fluidic structure and optical components. The fluidic structure includes a transparent channel through which objects in an analyte fluid can travel along respective paths during operation of the apparatus. The optical components are configured to provide measurement light to the objects traveling through the transparent channel. The fluidic structure is configured to reversibly engage with a host structure. The host structure includes a source of the measurement light and electronics to receive and process output light emanating from the objects traveling in the channel. The fluidic structure makes an air-tight seal when engaged with the host structure.
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公开(公告)号:US20190011491A1
公开(公告)日:2019-01-10
申请号:US15643427
申请日:2017-07-06
Applicant: Palo Alto Research Center Incorporated
Inventor: Ajay Raghavan , Peter Kiesel
Abstract: A monitoring system for a power grid includes one or more power transformer monitors. Each power transformer monitor includes a plurality of optical sensors disposed on one or more optical fibers that sense parameters of the power transformer. Each optical sensor is configured to sense a power transformer parameter that is different from a power transformer parameter sensed by at least one other sensor of the plurality of optical sensors. An optical coupler spatially disperses optical signals from the optical sensors according to wavelength. A detector unit converts optical signals of the optical sensors to electrical signals representative of the sensed power transformer parameters.
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公开(公告)号:US10064995B2
公开(公告)日:2018-09-04
申请号:US15209450
申请日:2016-07-13
Applicant: Palo Alto Research Center Incorporated
Inventor: Peter Kiesel , Joerg Martini , Eugene M. Chow , Scott Uhland , Noble M. Johnson
Abstract: Approaches for determining the delivery success of a particle, such as a drug particle, are disclosed. A system for monitoring delivery of particles to biological tissue includes a volume, an optical component, a detector, and an analyzer. The volume comprises a space through which a particle can pass in a desired direction. The optical component is configured to provide a measurement light. The detector is positioned to detect light emanating from the particle in response to the measurement light. The detected light is modulated as the particle moves along a detection axis. The detector is configured to generate a time-varying signal in response to the detected light. The analyzer is configured to receive the time-varying signal and determine a delivery success of the particle into a biological tissue based upon characteristics of the time-varying signal.
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公开(公告)号:US20180237820A1
公开(公告)日:2018-08-23
申请号:US15960049
申请日:2018-04-23
Applicant: Palo Alto Research Center Incorporated
Inventor: Joerg Martini , Michael Recht , Peter Kiesel
Abstract: One or more live substances is cultured at a plurality of test locations of a test vessel. The test locations include a thermochromic material and one or more test substances. A spectral shift in light emanating from the thermochromic material of the test locations is detected. The spectral shift occurs in response to an increase or decrease in energy conversion by the live substance. An effect of the one or more test substances on the live substances is determined based on the detected spectral shift.
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公开(公告)号:US09759657B2
公开(公告)日:2017-09-12
申请号:US14576156
申请日:2014-12-18
Applicant: Palo Alto Research Center Incorporated
Inventor: Peter Kiesel , Joerg Martini , Michael I. Recht
IPC: G01N21/64 , G01N33/542 , B01J19/00 , G01N33/543 , G01N33/58
CPC classification number: G01N21/6428 , B01J19/0046 , B01J2219/00545 , B01J2219/00576 , B01J2219/00587 , B01J2219/00596 , G01N21/6452 , G01N33/542 , G01N33/54313 , G01N33/582 , G01N33/583 , G01N2021/6419 , G01N2021/6421 , G01N2021/6441
Abstract: Analysis of a system and/or sample involves the use of absorption-encoded micro beads. Each type of micro bead is encoded with amounts of the k dyes in a proportional relationship that is different from proportional relationships of the k dyes of others of the n types of absorption-encoded micro beads. A system and/or a sample can be analyzed using information obtained from detecting the one or more types of absorption-encoded micro beads.
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公开(公告)号:US20170191107A1
公开(公告)日:2017-07-06
申请号:US14984739
申请日:2015-12-30
Applicant: Palo Alto Research Center Incorporated
Inventor: Joerg Martini , Michael Recht , Peter Kiesel
Abstract: One or more live substances is cultured at a plurality of test locations of a test vessel. The test locations include a thermochromic material and one or more test substances. A spectral shift in light emanating from the thermochromic material of the test locations is detected. The spectral shift occurs in response to an increase or decrease in energy conversion by the live substance. An effect of the one or more test substances on the live substances is determined based on the detected spectral shift.
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90.
公开(公告)号:US09528925B2
公开(公告)日:2016-12-27
申请号:US14181560
申请日:2014-02-14
Applicant: Palo Alto Research Center Incorporated
Inventor: Doron Kletter , Joerg Martini , Marshall W. Bern , Noble M. Johnson , Peter Kiesel , Bowen Cheng , Michael I. Recht
CPC classification number: G01N15/1459 , G01N15/1429 , G01N2015/0038 , G01N2015/0053 , G01N2015/1006 , G01N2021/8592
Abstract: Approaches for determining object position in a flow path are disclosed. A system includes a spatial filter having a length disposed along a longitudinal axis of the flow path and a width along a lateral axis of the flow path. The spatial filter has mask features configured to modulate light. Light emanating from objects moving along the flow path is detected. The detected light has a component along a detection axis that makes a non-zero angle with respect to the longitudinal and lateral axes. An electrical output signal that includes information about the trajectory depth of the object is generated in response to the detected light.
Abstract translation: 公开了用于确定流路中的物体位置的方法。 一种系统包括具有沿流动路径的纵向轴线设置的长度和沿着流动路径的横向轴线的宽度的空间过滤器。 空间滤波器具有配置为调制光的掩模特征。 检测从沿着流路移动的物体发出的光。 检测到的光具有沿着检测轴的分量,其相对于纵轴和横轴成非零角度。 响应于检测到的光而产生包括关于物体的轨迹深度的信息的电输出信号。
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