中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

18 records (took 0.022 seconds)

    Process for preparing 3,6-dihydro-1,3,5-triazine derivatives
    1.
    发明授权
    Process for preparing 3,6-dihydro-1,3,5-triazine derivatives 有权
    制备3,6-二氢-1,3,5-三嗪衍生物的方法

    公开(公告)号：US08703940B2

    公开(公告)日：2014-04-22

    申请号：US12742286

    申请日：2008-11-12

    Applicant: Benjamin List ,  Xu Cheng

    Inventor： Benjamin List ,  Xu Cheng

    IPC: C07D251/18

    CPC classification number: C07D251/48

    Abstract: A process for the synthesis of 3,6-dihydro-1,3,5-triazine derivatives is claimed wherein a biguanid is reacted with acetaldehyde in the presence of an inorganic and/or organic base. The process can be carried out at mild and therefore economical reaction conditions.

    Abstract translation: 要求合成3,6-二氢-1,3,5-三嗪衍生物的方法，其中在无机和/或有机碱的存在下，双胍与乙醛反应。 该方法可以在温和且经济的反应条件下进行。

    Aldol consensations by catalytic antibodies
    6.
    发明授权
    Aldol consensations by catalytic antibodies 失效
    通过催化抗体的Aldol认可

    公开(公告)号：US06589766B1

    公开(公告)日：2003-07-08

    申请号：US09965512

    申请日：2001-09-25

    Applicant: Carlos F. Barbas ,  Richard A. Lerner ,  Guofu Zhong ,  Benjamin List

    Inventor： Carlos F. Barbas ,  Richard A. Lerner ,  Guofu Zhong ,  Benjamin List

    IPC: C12P726

    CPC classification number: C12P7/26 ,  C12N9/0002

    Abstract: Catalytic antibodies, including 38C2 and 33F12, are capable of efficiently catalyzing a wide variety of ketone-ketone, ketone-aldehyde, aldehyde-ketone, and aldehyde-aldehyde intermolecular aldol reactions, and in some cases to catalyze their subsequent dehydration to yield aldol condensation products. A number of intramolecular aldol reactions have also been defined. Catalysis of all intramolecular aldol reactions examined yields the corresponding condensation products.

    Abstract translation: 包括38C2和33F12在内的催化抗体能够有效地催化各种酮 - 酮，酮 - 醛，醛 - 酮和醛 - 醛分子间醛醇反应，并且在某些情况下催化它们随后的脱水以产生醛醇缩合 产品。 还定义了许多分子内醛醇反应。 所检测的所有分子内醛醇反应的催化产生相应的缩合产物。

    Aldol condensations by catalytic antibodies
    7.
    发明授权
    Aldol condensations by catalytic antibodies 失效
    通过催化抗体的醛醇缩合

    公开(公告)号：US06326176B1

    公开(公告)日：2001-12-04

    申请号：US09573753

    申请日：2000-05-18

    Applicant: Carlos F. Barbas ,  Richard A. Lerner ,  Guofu Zhong ,  Benjamin List

    Inventor： Carlos F. Barbas ,  Richard A. Lerner ,  Guofu Zhong ,  Benjamin List

    IPC: C12P726

    CPC classification number: C12P7/26 ,  C12N9/0002

    Abstract: Catalytic antibodies, including 38C2 and 33F12, are capable of efficiently catalyzing a wide variety of ketone-ketone, ketone-aldehyde, aldehyde-ketone, and aldehyde-aldehyde intermolecular aldol reactions, and in some cases to catalyze their subsequent dehydration to yield aldol condensation products. A number of intramolecular aldol reactions have also been defined. Catalysis of all intramolecular aldol reactions examined yields the corresponding condensation products.

    Abstract translation: 包括38C2和33F12在内的催化抗体能够有效地催化各种酮 - 酮，酮 - 醛，醛 - 酮和醛 - 醛分子间醛醇反应，并且在某些情况下催化它们随后的脱水以产生醛醇缩合 产品。 还定义了许多分子内醛醇反应。 所检测的所有分子内醛醇反应的催化产生相应的缩合产物。

    Chiral disulfonimides
    8.
    发明授权
    Chiral disulfonimides 有权
    手性二磺酰亚胺

    公开(公告)号：US09079869B2

    公开(公告)日：2015-07-14

    申请号：US13203382

    申请日：2010-03-02

    Applicant: Benjamin List ,  Frank Lay ,  Pilar Garcia Garcia

    Inventor： Benjamin List ,  Frank Lay ,  Pilar Garcia Garcia

    IPC: A61K31/554 ,  C07D285/36 ,  C07D285/01

    CPC classification number: C07D285/01

    Abstract: Chiral disulfonimides having the formula I to III, wherein at least one of the groups A and B in the compound of formula I, C and D of the compound in formula II, and E and F of the compound in formula III is a chiral group, or E and F together form a chiral backbone, X is C, Si, O, N or S, and n is 0, 1, 2, 3, 4, 5 or 6, where n is >1 only if X is C, and G is as defined herein, and to the organic salts, metal salts and metal complexes thereof, are suited as NMR shift reagents and as reagents for racemate splitting, and also as chiral Brønsted acid catalysts or chiral Lewis acid catalysts for activating ketones, aldehydes and alkenes, and also as catalysts in the organic synthesis.

    Abstract translation: 具有式I至III的手性二磺酰亚胺，其中式I化合物中的基团A和B中至少一个，式II化合物中的C和D，以及式III中化合物的E和F是手性基团 ，或E和F一起形成手性主链，X为C，Si，O，N或S，n为0,1,2,3,4,5或6，其中只有X为C时，n为> 1 和G如本文所定义，并且其有机盐，金属盐和金属络合物适合用作NMR位移试剂和用作外消旋体分裂的试剂，以及用作活化酮的手性布朗斯台德酸催化剂或手性路易斯酸催化剂， 醛和烯烃，以及有机合成中的催化剂。

    Method for producing chiral α,β-epoxy ketones
    10.
    发明授权
    Method for producing chiral α,β-epoxy ketones 失效
    制备手性α，β-环氧酮的方法

    公开(公告)号：US08471046B2

    公开(公告)日：2013-06-25

    申请号：US12920877

    申请日：2009-03-12

    Applicant: Benjamin List ,  Corinna Reisinger ,  Xingwang Wang

    Inventor： Benjamin List ,  Corinna Reisinger ,  Xingwang Wang

    IPC: C07D301/12

    CPC classification number: C07D301/12

    Abstract: A process is claimed for the enantioselective epoxidation of α,β-unsaturated ketones, in which a compound of the general formula I, is reacted with an oxidizing agent to form α,β-epoxy ketones of the general formula II, in which R1, R2, R3 are as defined above. The α,β-epoxy ketones of the general formula II can be obtained in good yields and outstanding enantioselectivities from α,β-unsaturated ketones of the general formula I by epoxidation with hydrogen peroxide in the presence of a chiral catalyst, such as amino compounds and their acid addition salts.

    Abstract translation: 要求对α，β-不饱和酮进行对映选择性环氧化的方法，其中通式I的化合物与氧化剂反应形成通式II的α，β-环氧酮，其中R1， R2，R3如上所定义。 通式II的α，β-环氧酮可以通过在手性催化剂如氨基化合物的存在下用过氧化氢进行环氧化，以良好的收率和通式I的α，β-不饱和酮的优异的对映选择性获得。 和它们的酸加成盐。

Patent Agency Ranking