公开(公告)号：US08593107B2

公开(公告)日：2013-11-26

申请号：US12605579

申请日：2009-10-26

Applicant: Avi Penner ,  Eyal Doron ,  Jeffrey E. Stahmann ,  Keith R. Maile ,  Binh C. Tran ,  Wangcai Liao ,  Bin Mi ,  Paul J. Huelskamp

Inventor： Avi Penner ,  Eyal Doron ,  Jeffrey E. Stahmann ,  Keith R. Maile ,  Binh C. Tran ,  Wangcai Liao ,  Bin Mi ,  Paul J. Huelskamp

IPC: H01M10/44

CPC classification number: A61B5/0215 ,  A61B5/0031 ,  A61B5/01 ,  A61B5/026 ,  A61N1/37217 ,  A61N1/3787

Abstract: Methods, systems, and apparatus for recharging medical devices implanted within the body are disclosed. An illustrative method of recharging an implanted medical device includes delivering a charging device to a location adjacent to the implanted medical device, activating a charging element coupled to the charging device and transmitting charging energy to a receiver of the implanted medical device, and charging the implanted medical device using the transmitted charging energy from the charging device.

Abstract translation: 公开了用于对植入体内的医疗器械进行再充电的方法，系统和装置。 对植入式医疗装置再充电的说明性方法包括将充电装置传送到与植入的医疗装置相邻的位置，激活耦合到充电装置的充电元件，并将充电能量传输到植入的医疗装置的接收器， 使用来自充电装置的传输的充电能量的医疗装置。

公开(公告)号：US20130144174A1

公开(公告)日：2013-06-06

申请号：US13674639

申请日：2012-11-12

Applicant: John D. Hatlestad ,  Binh C Tran ,  Bin Mi ,  Ronald W. Heil, Jr.

Inventor： John D. Hatlestad ,  Binh C Tran ,  Bin Mi ,  Ronald W. Heil, Jr.

IPC: A61B5/0205 ,  A61B5/03 ,  A61B5/20

CPC classification number: A61B5/0205 ,  A61B5/0028 ,  A61B5/0031 ,  A61B5/03 ,  A61B5/036 ,  A61B5/201 ,  A61B5/416 ,  A61B5/6846

Abstract: An implantable system for ambulatory monitoring of a high-risk heart failure patient includes a first pressure sensor implantable within an abdomen of the patient for sensing and generating an output representative of a baseline intra-abdominal pressure value of the patient and for chronically sensing and generating an output representative of an intra-abdominal pressure value of the patient at periodic intervals. At least one second implantable sensor is provided for sensing and generating an output representative of a second physiological parameter of the patient. Additionally, the system includes a processor for correlating the output of the first pressure sensor and the second physiologic sensor, and for comparing differences between the baseline intra-abdominal pressure value and subsequent intra-abdominal pressure values. The processor can reside in another implantable device or in an external device/system.

Abstract translation: 用于高风险心力衰竭患者的动态监测的可植入系统包括可植入患者腹部的第一压力传感器，用于感测和产生代表患者的基线腹内压力值的输出，并且用于长期感测和产生 以周期性间隔代表患者的腹内压力值的输出。 提供至少一个第二可植入传感器用于感测和产生代表患者的第二生理参数的输出。 另外，该系统包括用于将第一压力传感器和第二生理传感器的输出相关联并且用于比较基线腹内压力值和随后的腹内压力值之间的差异的处理器。 处理器可以驻留在另一个可植入设备中或外部设备/系统中。

公开(公告)号：US20110190669A1

公开(公告)日：2011-08-04

申请号：US13082954

申请日：2011-04-08

Applicant: Bin Mi ,  Abhijeet V. Chavan ,  Keith R. Maile

Inventor： Bin Mi ,  Abhijeet V. Chavan ,  Keith R. Maile

IPC: A61N7/00

CPC classification number: A61N1/37288 ,  A61B5/0028 ,  A61N1/37217

Abstract: Implantable medical devices including an ultrasonic transducer and methods of optimizing an ultrasonic transducer of an implantable medical device are disclosed. The implantable medical device can include a housing, an ultrasonic transducer disposed within an interior of the housing, and a limiting structure configured to constrain deformation of the ultrasonic transducer. The limiting structure can include a separate structure coupled to the housing, or can comprise a resonant portion of the housing itself. During operation, the ultrasonic transducer is configured to communicate at a frequency at or near a resonant frequency of the housing.

Abstract translation: 公开了包括超声换能器和优化可植入医疗装置的超声换能器的方法的可植入医疗装置。 可植入医疗装置可以包括壳体，设置在壳体内部的超声波换能器以及限制超声换能器变形的限制结构。 限制结构可以包括耦合到壳体的单独结构，或者可以包括壳体本身的谐振部分。 在操作期间，超声波换能器被配置为在壳体的谐振频率处或接近谐振频率处的频率进行通信。

公开(公告)号：US07912548B2

公开(公告)日：2011-03-22

申请号：US11781023

申请日：2007-07-20

Applicant: Bin Mi ,  Abhijeet V. Chavan ,  John H. Tangren

Inventor： Bin Mi ,  Abhijeet V. Chavan ,  John H. Tangren

IPC: A61N1/375

CPC classification number: A61N1/37217

Abstract: An implantable medical device comprising a housing and a limiting structure defining a resonant region in the housing. An acoustic transducer is connected to the limiting structure and extends into the resonant region so that the resonant region mechanically amplifies the deformation of the acoustic transducer at a resonant frequency. An implantable medical device comprising a housing and a limiting structure defining a resonant region in the housing. An acoustic transducer having the shape of a beam is mechanically coupled to the limiting structure and partially extends into the resonant region so that the resonant region mechanically amplifies the deformation of the acoustic transducer at a resonant frequency. An implantable medical device comprising a housing, an acoustic transducer coupled to the housing, and a means for mechanically amplifying the deformation of the acoustic transducer at a resonant frequency. The means defines a resonant region in the housing.

Abstract translation: 一种可植入医疗装置，其包括壳体和限定壳体中的谐振区域的限制结构。 声学换能器连接到限制结构并延伸到谐振区域，使得谐振区域以谐振频率机械放大声学换能器的变形。 一种可植入医疗装置，其包括壳体和限定壳体中的谐振区域的限制结构。 具有光束形状的声换能器机械耦合到限制结构，并且部分地延伸到谐振区域中，使得谐振区域以谐振频率机械放大声换能器的变形。 一种可植入医疗装置，包括壳体，耦合到壳体的声换能器，以及用于以谐振频率机械放大声换能器的变形的装置。 该装置限定壳体中的谐振区域。

公开(公告)号：US20100317978A1

公开(公告)日：2010-12-16

申请号：US12774990

申请日：2010-05-06

Applicant: Keith R. Maile ,  Abhijeet V. Chavan ,  Thomas W. Piaget ,  Bin Mi

Inventor： Keith R. Maile ,  Abhijeet V. Chavan ,  Thomas W. Piaget ,  Bin Mi

IPC: A61B5/0215 ,  A61B5/00 ,  A61B5/03 ,  H02N2/18

CPC classification number: H01L41/1138 ,  A61B5/0031 ,  A61B5/0215 ,  H02N2/18

Abstract: Methods, systems, and apparatus for powering and/or recharging medical devices implanted within the body are described. An illustrative implantable sensor for sensing one or more physiologic parameters within a body lumen includes a housing having an exterior wall that has an inner surface and an outer surface and that defines an internal cavity. A portion of the housing includes an electrically conductive material that functions as a first electrical conductor. A flexible piezoelectric layer is disposed adjacent to a portion of the exterior wall and a second electrical conductor is disposed adjacent to the piezoelectric layer. The piezoelectric layer is configured to displace in response to periodic pressure pulses within the body lumen and generate a voltage differential between the first and second electrical conductors.

Abstract translation: 描述了植入体内的医疗装置的供电和/或再充电的方法，系统和装置。 用于感测体腔内的一个或多个生理参数的说明性可植入传感器包括具有外壁的壳体，所述外壁具有内表面和外表面，并且限定内腔。 壳体的一部分包括用作第一电导体的导电材料。 柔性压电层设置成与外壁的一部分相邻，并且第二电导体邻近压电层设置。 压电层被配置为响应于体腔内的周期性压力脉冲而移位，并在第一和第二电导体之间产生电压差。

公开(公告)号：US20100049269A1

公开(公告)日：2010-02-25

申请号：US12611686

申请日：2009-11-03

Applicant: Binh C. Tran ,  Robert S. Harguth ,  Bin Mi ,  Keith R. Maile

Inventor： Binh C. Tran ,  Robert S. Harguth ,  Bin Mi ,  Keith R. Maile

IPC: A61N1/08 ,  A61N1/365

CPC classification number: A61N1/3787 ,  A61N1/37217

Abstract: An acoustic energy delivery system for delivering acoustic energy to an implantable medical device (“IMD”). The system includes an IMD having a power source and an energy delivery device. The energy delivery device includes a controller and an array of ultrasonic elements electrically coupled to the controller and configured to deliver acoustic energy to the IMD. Methods of delivering acoustic energy to an IMD are also disclosed.

Abstract translation: 用于将声能递送到可植入医疗装置（“IMD”）的声能递送系统。 该系统包括具有电源和能量输送装置的IMD。 能量输送装置包括控制器和电耦合到控制器并被配置为向IMD传送声能的超声波元件阵列。 还公开了向IMD传递声能的方法。

公开(公告)号：US20090228078A1

公开(公告)日：2009-09-10

申请号：US12327601

申请日：2008-12-03

Applicant: Yunlong Zhang ,  Haresh G. Sachanandani ,  Dan Li ,  Bin Mi

Inventor： Yunlong Zhang ,  Haresh G. Sachanandani ,  Dan Li ,  Bin Mi

IPC: A61N1/36

CPC classification number: A61N1/0587 ,  A61B5/4035 ,  A61B5/6862 ,  A61B5/6876 ,  A61N1/057 ,  A61N1/36114 ,  A61N1/36117 ,  A61N1/3627 ,  A61N1/37211 ,  A61N1/37288

Abstract: Various implantable medical device embodiments stimulate an autonomic neural target from within a pulmonary artery, and comprise at least one electrode, a power supply, a neural stimulator connected to the power supply, and an anchor structure. The neural stimulator is configured to generate a neural stimulation signal for delivery to the neural stimulation target through the at least one electrode. The anchor structure is configured to chronically and securely implant the neural stimulator, the power supply and the at least one electrode within the pulmonary artery. The anchor structure, the neural stimulator, the power supply and the at least one electrode are configured to be implanted through a pulmonary valve into the pulmonary artery. In various embodiments, the neural stimulator is configured to be operational to implement a neural stimulation protocol when chronically implanted within the pulmonary artery without a wired connection through the pulmonary valve.

Abstract translation: 各种可植入医疗装置实施例从肺动脉内刺激自主神经靶标，并且包括至少一个电极，电源，连接到电源的神经刺激器和锚结构。 神经刺激器被配置为产生神经刺激信号，以通过至少一个电极传递到神经刺激靶。 锚结构被配置为长期且牢固地植入神经刺激器，电源和至少一个电极在肺动脉内。 锚结构，神经刺激器，电源和至少一个电极构造成通过肺动脉瓣植入肺动脉。 在各种实施例中，神经刺激器被配置为在长期植入肺动脉内而不通过肺动脉瓣的有线连接的情况下实施神经刺激方案。

公开(公告)号：US20090025459A1

公开(公告)日：2009-01-29

申请号：US11781769

申请日：2007-07-23

Applicant: Yunlong Zhang ,  Bin Mi

Inventor： Yunlong Zhang ,  Bin Mi

IPC: G01N11/10

CPC classification number: A61B5/0031 ,  A61B5/6882

Abstract: An apparatus includes an implantable acoustic viscosity sensor configured to acoustically obtain a viscosity signal indicative of a viscosity of a fluid in contact with the viscosity sensor. A viscosity measurement circuit produces a viscosity measurement from the viscosity signal.

Abstract translation: 一种装置包括可植入声学粘度传感器，其构造成声学地获得指示与粘度传感器接触的流体的粘度的粘度信号。 粘度测量电路根据粘度信号产生粘度测量。

公开(公告)号：US20080021510A1

公开(公告)日：2008-01-24

申请号：US11781023

申请日：2007-07-20

Applicant: Bin Mi ,  Abhijeet Chavan ,  John Tangren

Inventor： Bin Mi ,  Abhijeet Chavan ,  John Tangren

IPC: A61N1/362

CPC classification number: A61N1/37217

Abstract: An implantable medical device comprising a housing and a limiting structure defining a resonant region in the housing. An acoustic transducer is connected to the limiting structure and extends into the resonant region so that the resonant region mechanically amplifies the deformation of the acoustic transducer at a resonant frequency. An implantable medical device comprising a housing and a limiting structure defining a resonant region in the housing. An acoustic transducer having the shape of a beam is mechanically coupled to the limiting structure and partially extends into the resonant region so that the resonant region mechanically amplifies the deformation of the acoustic transducer at a resonant frequency. An implantable medical device comprising a housing, an acoustic transducer coupled to the housing, and a means for mechanically amplifying the deformation of the acoustic transducer at a resonant frequency. The means defines a resonant region in the housing.

Abstract translation: 一种可植入医疗装置，其包括壳体和限定壳体中的谐振区域的限制结构。 声学换能器连接到限制结构并延伸到谐振区域，使得谐振区域以谐振频率机械放大声学换能器的变形。 一种可植入医疗装置，其包括壳体和限定壳体中的谐振区域的限制结构。 具有光束形状的声换能器机械耦合到限制结构，并且部分地延伸到谐振区域中，使得谐振区域以谐振频率机械放大声换能器的变形。 一种可植入医疗装置，包括壳体，耦合到壳体的声换能器，以及用于以谐振频率机械放大声换能器的变形的装置。 该装置限定壳体中的谐振区域。

公开(公告)号：US20080021509A1

公开(公告)日：2008-01-24

申请号：US11780992

申请日：2007-07-20

Applicant: Bin Mi ,  Abhijeet V. Chavan ,  Keith R. Maile

Inventor： Bin Mi ,  Abhijeet V. Chavan ,  Keith R. Maile

IPC: A61N1/02

CPC classification number: A61N1/37288 ,  A61B5/0028 ,  A61N1/37217

Abstract: An implantable medical device comprising a housing and an ultrasonic transducer having a communication frequency coupled to a portion of the housing. The housing resonates at the communication frequency, and a casing is coupled to the housing and disposed over the ultrasonic transducer. The casing is adapted to amplify the deformation of the ultrasonic transducer in a bending mode and transfer the bending moment to the housing. An implantable medical device comprising a housing having an upper portion and a lower portion. A first ultrasonic transducer is coupled to a first connection rod and is coaxial with the first connection rod. The first ultrasonic transducer and first connection rod are interposed between the upper and lower portions such that the first ultrasonic transducer is adapted to vibrate the upper and lower portions simultaneously. A method of optimizing an ultrasonic transducer and a housing of an implantable medical device.

Abstract translation: 一种可植入医疗装置，包括壳体和具有耦合到壳体的一部分的通信频率的超声换能器。 壳体以通信频率谐振，并且壳体耦合到壳体并且设置在超声换能器上。 壳体适于在弯曲模式下放大超声波换能器的变形，并将弯矩转移到壳体。 一种可植入医疗装置，包括具有上部和下部的壳体。 第一超声换能器联接到第一连接杆并且与第一连接杆同轴。 第一超声波换能器和第一连接杆插入在上部和下部之间，使得第一超声波换能器适于同时振动上部和下部。 一种优化超声换能器和可植入医疗装置的壳体的方法。