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公开(公告)号:US20010033670A1
公开(公告)日:2001-10-25
申请号:US09859191
申请日:2001-05-15
Inventor: Yu-Chong Tai , Tseng-Yang Hsu , Wen H. Hsieh
IPC: H04R017/00 , H04R025/00
CPC classification number: H04R19/016 , H04R25/604 , Y10T29/42 , Y10T29/49005 , Y10T29/49226
Abstract: An electret formed by micro-machining technology on a support surface, including a self-powered electret sound transducer, preferably in the form of a microphone, formed by micro-machining technology. Each microphone is manufactured as a two-piece unit, comprising a microphone membrane unit and a microphone back plate, at least one of which includes an electret formed by micro-machining technology. When juxtaposed, the two units form a microphone that can produce a signal without the need for external biasing, thereby reducing system volume and complexity. The electret material used is a thin film of spin-on polytetrafluoroethylene (PTFE). An electron gun preferably is used for charge implantation. The electret has a saturated charged density in the range of about 2null10null5 C/m2 to about 8null10null4 C/m2. Thermal annealing is used to stabilize the implanted charge. An open circuit sensitivity of about 0.5 mV/Pa has been achieved for a hybrid microphone package.
Abstract translation: 通过微加工技术在支撑表面上形成的驻极体,其包括通过微加工技术形成的优选以麦克风形式的自供电的驻极体声音传感器。 每个麦克风被制造成两件式的单元,其包括麦克风膜单元和麦克风背板,其中至少一个包括由微加工技术形成的驻极体。 当并置时,两个单元形成麦克风,其可以产生信号而不需要外部偏置,从而降低系统体积和复杂性。 使用的驻极体材料是旋涂聚四氟乙烯(PTFE)的薄膜。 电子枪优选用于电荷注入。 驻极体的饱和带电密度在约2×10 -5 C / m 2至约8×10 -4 C / m 2的范围内。 热退火用于稳定植入电荷。 对于混合麦克风封装已经实现了约0.5mV / Pa的开路灵敏度。
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公开(公告)号:US20250152743A1
公开(公告)日:2025-05-15
申请号:US18945412
申请日:2024-11-12
Applicant: California Institute of Technology
Inventor: Michael B. Elowitz , Shiyu Xia , Andrew C. Lu , Lukas Moeller
Abstract: Disclosed herein include methods, compositions, and kits suitable for use in programmable cell death control. Compositions (e.g., nucleic acid compositions, synthetic protein circuits) provided herein can comprise one or more apoptosis polypeptides; and/or one or more pyroptosis polypeptides; and/or one or more input polypeptides. In some embodiments, expression of a synthetic protein circuit of the disclosure can induce, e.g., apoptosis and/or pyroptosis in a cell.
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公开(公告)号:US12300712B2
公开(公告)日:2025-05-13
申请号:US17938838
申请日:2022-10-07
Applicant: California Institute of Technology
Inventor: David Z. Ting , Sam A. Keo , Arezou Khoshakhlagh , Alexander Soibel , Sarath D. Gunapala
IPC: H01L27/146
Abstract: Disclosed herein is an infrared detector. The detector includes a plurality of pixels. Each pixel includes an n-type semiconductor top contact layer, a p-type semiconductor layer electrically connected to the n-type top contact layer to form a top p-n junction, a unipolar electron barrier electrically connected to the p-type semiconductor layer, a bottom absorber, and an n-type semiconductor bottom contact layer electrically connected to the bottom absorber. The unipolar electron barrier is positioned between the p-type semiconductor layer and the bottom absorber.
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公开(公告)号:US12297230B2
公开(公告)日:2025-05-13
申请号:US18316102
申请日:2023-05-11
Applicant: California Institute of Technology
Inventor: Lucy S. Chong , Ronghui Zhu , Xiaofei Ge , Michael B. Elowitz , Mark W. Budde
Abstract: Disclosed herein include methods, compositions, and kits suitable for use in thresholding of protein signals. There are provided, in some embodiments, synthetic protein circuits that respond to inputs only above or below a certain threshold concentration. In some embodiments, the threshold value itself is tunable. Methods of treating a disease or disorder characterized by aberrant signaling are provided in some embodiments.
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公开(公告)号:US20250143589A1
公开(公告)日:2025-05-08
申请号:US18935159
申请日:2024-11-01
Applicant: California Institute of Technology
Inventor: Simon Mahler , Yu Xi Huang , Changhuei Yang
IPC: A61B5/0205 , A61B5/00 , A61B5/02 , A61B5/024 , A61B5/0255 , A61B5/026
Abstract: Techniques for monitoring cerebral blood metrics such as cerebral blood flow, cerebral blood volume and/or heart rate are provided. In some embodiments, techniques involve a headset with at least one laser configured to emit light into the brain and one or more light detectors such as CMOS sensors that generate information indicative of light reflected from one or more structures within the brain, which can be used to determine the cerebral blood metrics. Each light detector may be positioned within 5 mm of the scalp in some cases.
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6.
公开(公告)号:US12285331B2
公开(公告)日:2025-04-29
申请号:US16820274
申请日:2020-03-16
Applicant: Foldax, Inc. , California Institute of Technology
Inventor: Garrett Johnson , Jason G. Beith , Marek Lhotak , Praveen De Silva , Peter Millson , Francis P. Maguire , Morteza Gharib
Abstract: Improved prosthetic valves, their methods of manufacture, and systems and devices for manufacturing the valves are described. The prosthetic valves can be configured for transcatheter implantation. The prosthetic valves can have artificial leaflets. The prosthetic valves can be manufactured in numerous ways, such as by polymeric dipping processes and/or electrospinning. Sponge-like polymers for valves and other medical devices are also disclosed.
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公开(公告)号:US20250129488A1
公开(公告)日:2025-04-24
申请号:US18917743
申请日:2024-10-16
Inventor: Karthish MANTHIRAM , Minju CHUNG
IPC: C25B3/07 , C25B3/23 , C25B9/23 , C25B11/032 , C25B11/052 , C25B11/065 , C25B11/075
Abstract: Methods and systems for the electrochemical epoxidation of alkenes to generate an epoxide are described herein. Said methods and systems comprise: contacting an anode comprising an oxygen atom transfer electrocatalyst with an alkene in the presence of an electrolyte comprising water; applying a voltage to the anode and a cathode to generate the epoxide; wherein the oxygen atom transfer electrocatalyst comprises an at least partially oxidized palladium-platinum alloy characterized by the formula FX1: PdyPtzOx; wherein y is greater than 0 and less than 1; z is greater than 0 and less than 1; wherein the sum of y and z is equal to 1; and x is selected from the range of 0 to 2. The methods and systems disclosed herein comprise a significant advancement in the electrocatalytic epoxidation of alkenes in aqueous and mixed electrolytes using water as the oxygen atom transfer source.
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公开(公告)号:US20250127610A1
公开(公告)日:2025-04-24
申请号:US18508701
申请日:2023-11-14
Inventor: Yu-Chong Tai , Mark S. Humayun
IPC: A61F2/16
Abstract: An intraocular lens (IOL) has a small, central lens suspended within a pliable housing and, when the housing is filled with liquid, is coaxially aligned with a second small lens embedded in the wall of the housing. The suspension is on a dome- or other-shaped webbing attached to an inner circumference of the wall. When filled with liquid, forces squeezing or pulling the equator of the housing, as with ciliary muscles in the eye, adjust a distance between the lenses in order to adjust focus. Optional haptics may project from points on or above and below the equator. A recess in the posterior hemisphere of the housing can keep cell growth away from an optical axis of the lens system. A third small lens can be embedded in an opposite wall of the housing and coaxially aligned with the other lenses to form a three-lens, ultra-zoom system.
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公开(公告)号:US12283827B2
公开(公告)日:2025-04-22
申请号:US18093291
申请日:2023-01-04
Applicant: California Institute of Technology
Inventor: Seyed Ali Hajimiri , Florian Bohn , Behrooz Abiri
Abstract: A device includes, in part, an antenna adapted to receive an RF signal that includes modulated data, a splitter/coupler adapted to split the received RF signal, a receiver adapted to demodulate the data from a first portion of the RF signal, and a power recovery unit adapted to convert to a DC power a second portion of the RF signal. The splitter/coupler is optionally adjustable to split the RF signal in accordance with a value that may be representative of a number of factors, such as the target data rate, the DC power requirement of the device, and the like. The device optionally includes a switch and/or a power combiner adapted to deliver all the received RF power to the receiver depending on any number of operation conditions of the device or the device's distance from an RF transmitting device.
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10.
公开(公告)号:US12281190B2
公开(公告)日:2025-04-22
申请号:US17636048
申请日:2020-08-18
Inventor: Theodor Agapie , Shuoyan Xiong , Brad C. Bailey , Heather A. Spinney , Alex J. Nett , David R. Wilson , Jerzy Klosin
IPC: C08F4/80 , B01J31/24 , C08F4/70 , C08F210/02
Abstract: Processes of polymerizing olefin monomers using catalyst systems and catalysts systems that include a procatalyst having a structure according to formula (I): (I).
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