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公开(公告)号:US5856102A
公开(公告)日:1999-01-05
申请号:US806205
申请日:1997-02-26
Applicant: Diane Lynn Bierke-Nelson , Stuart James Nelson , Joshua James Nelson , Jesse Stuart Nelson
Inventor: Diane Lynn Bierke-Nelson , Stuart James Nelson , Joshua James Nelson , Jesse Stuart Nelson
CPC classification number: C12N15/10 , C12Q1/68 , Y10S435/81
Abstract: The invention is the improved process and method of DNA banking in which DNA or other genetic material is collected and stored, preserved, banked in a home/self-storage setting. Home/self-storage is to mean "not commercially banked." The invention includes the manufacture of kits designed to collect and bank DNA and other genetic material in a home/self-storage setting. The objective of the invention is to preserve genetic material in the event that it is needed for genetic analysis, genetic testing, genetic diagnosis, genetic therapy, forensic analysis, identification.
Abstract translation: 本发明是改进的DNA银行的方法和方法,其中DNA或其他遗传物质被收集和储存,保存,存储在家庭/自存储环境中。 家庭/自助储蓄是指“不商业银行”。 本发明包括制造用于在家庭/自我储存环境中收集和储存DNA和其他遗传物质的试剂盒。 本发明的目的是在遗传分析,遗传检测,遗传诊断,遗传治疗,法医分析,鉴定等方面需要保存遗传物质。
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公开(公告)号:US20190073624A1
公开(公告)日:2019-03-07
申请号:US15695181
申请日:2017-09-05
Applicant: Lee Thomas Schaeffer , James Patrick Clayton , William Jennings Dearien , James Nelson Dearien, II
Inventor: Lee Thomas Schaeffer , James Patrick Clayton , William Jennings Dearien , James Nelson Dearien, II
Abstract: The present invention employs software, communication links and various Systems to expedite the purchase and delivery of items or services commonly used to assist stranded motorist(s) and/or disabled vehicles, manned or otherwise, through an automated Unmanned Aerial Vehicle (also identified herein as a UAV) dispatch, or by dispatching another type vehicle, and a Payment Fulfilment Platform distributed to serve a plurality of locations through the use of a communication device or plurality of communication devices. This software transmits request(s) for service by permitting a Customer, to select and/or change selections such as price, fuel grades, a particular service, parts and payment methods, as examples, prior to registering a dispatch to Vendor(s) on the System. The present invention is configured to expeditiously facilitate service(s) and/or product(s) from Vendor(s) to Customer(s).
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公开(公告)号:US10055984B1
公开(公告)日:2018-08-21
申请号:US15783351
申请日:2017-10-13
Applicant: Lee Schaeffer , Norman Seals , James Nelson Dearien, II , William Jennings Dearian
Inventor: Lee Schaeffer , Norman Seals , James Nelson Dearien, II , William Jennings Dearian
IPC: G08G1/095 , G08G1/09 , B64C39/02 , B64D47/08 , B60L11/18 , G08G1/04 , G08G1/048 , A61B5/01 , A61B5/024
CPC classification number: G08G1/09 , A61B5/002 , A61B5/01 , A61B5/024 , B60L53/30 , B60L2200/10 , B64C39/024 , B64C2201/12 , B64C2201/127 , B64C2201/128 , B64D47/08 , G08G1/04 , G08G1/048 , G08G1/0955 , G08G1/167 , Y02T10/7005 , Y02T10/7072 , Y02T90/12 , Y02T90/121 , Y02T90/14 , Y02T90/16
Abstract: An unmanned aerial vehicle (UAV) system includes a command center having a computing device an unmanned aerial vehicle (UAV) with a body, the UAV to communicate wirelessly with the command center via a network, the UAV having a control system with a power source, a geospatial tracking device, and a multi-channel communication portal; a camera secured to the body and in communication with the control system; and one or more equipment attachment sites; site assessment tools to attach to or within the one or more equipment attachment sites, each of the site assessment tools to record a data associated with an emergency site, such as weather conditions, road conditions, traffic, visibility, radiation, and chemical exposure; the UAV is to receive commands from the command center to deploy to the emergency site; and the UAV is to receive the data and transmit the data to the command center via the multi-channel communication portal.
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公开(公告)号:US08950349B2
公开(公告)日:2015-02-10
申请号:US13588959
申请日:2012-08-17
Applicant: Stephen P. Lindblade , William Louis Fontenot , James Nelson Pratt
Inventor: Stephen P. Lindblade , William Louis Fontenot , James Nelson Pratt
CPC classification number: B63B21/507 , F16C19/26 , F16C19/30 , F16C19/545 , F16C21/00 , F16C35/062 , F16C2237/00 , F16C2300/14 , F16C2326/00 , F16C2326/30 , Y10T29/4973
Abstract: A turret/vessel bearing arrangement and method for replacing bearings in situ without removing other bearings. The bearings are capable of being separated. A removable axial spacer secures the vessel and the turret into engagement with the upper and lower thrust bearings. Removal of the spacer allows increased separation between vessel and turret flanges that sandwich the thrust bearings. The mid radial bearing assembly includes one or more radially arranged bearing pads that allow for limited axial displacement of the turret with respect to the vessel during thrust bearing replacement while still bearing radial loads and allowing rotation. The addition of a temporary thrust bearing allows the vessel to weathervane about the turret while thrust bearing are replaced in situ.
Abstract translation: 一种用于在不移除其他轴承的情况下原位替换轴承的转塔/轴承装置和方法。 轴承能够分离。 可拆卸的轴向间隔件将容器和转台固定成与上部和下部推力轴承接合。 间隔件的拆卸允许增加夹紧推力轴承的容器和转塔凸缘之间的分离。 中径向轴承组件包括一个或多个径向布置的轴承瓦块,其允许在止推轴承更换期间转台相对于容器的有限的轴向位移,同时仍承受径向载荷并允许旋转。 临时止推轴承的添加允许船舶在转台周围进行风向标,同时在现场更换止推轴承。
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公开(公告)号:US08850626B2
公开(公告)日:2014-10-07
申请号:US13051896
申请日:2011-03-18
Applicant: Carlos D. Reyes , An Tran , James Nelson Castro , Errol Tazbaz , David Ginther
Inventor: Carlos D. Reyes , An Tran , James Nelson Castro , Errol Tazbaz , David Ginther
Abstract: Eyewear, such as a goggle, is provided that can include an anterior module (such as a lens support) and an interchangeable posterior module (such as a faceplate). The anterior module can be adapted to support at least one lens in a wearer's field of view. The posterior module can be adapted to fit against a contour of the wearer's face and can be selectively interchangeable with the anterior module to modify at least one physical characteristic of the eyewear. In some embodiments, the anterior and posterior modules can be coupled by a suspension assembly in order to allow articulation of the posterior module relative to the anterior module for evenly distributing forces against the wearer's face. Further, the anterior module can be rigid for maintaining the lens in an optically-desirable orientation. Furthermore, the goggle can comprise an interchangeable lens mechanism to facilitate interchanging of lenses in the goggle.
Abstract translation: 提供眼镜,例如护目镜,其可以包括前模块(例如透镜支架)和可互换的后模块(例如面板)。 前模块可以适于在佩戴者的视野中支撑至少一个透镜。 后模块可以适于与佩戴者的脸部轮廓相配合,并且可以与前模块选择性地互换,以修改眼镜的至少一个物理特性。 在一些实施例中,前部和后部模块可以通过悬挂组件联接,以便允许后部模块相对于前部模块铰接,以均匀地分配力抵抗穿着者的脸部。 此外,前模块可以是刚性的,用于将透镜保持在光学上期望的取向。 此外,护目镜可以包括可互换的透镜机构,以便于透镜在护目镜中的互换。
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公开(公告)号:US08800067B2
公开(公告)日:2014-08-12
申请号:US13051889
申请日:2011-03-18
Applicant: Ryan Saylor , An Tran , James Nelson Castro , Errol Tazbaz , David Ginther , Ryan Calilung
Inventor: Ryan Saylor , An Tran , James Nelson Castro , Errol Tazbaz , David Ginther , Ryan Calilung
IPC: A61F9/02
Abstract: Eyewear, such as a goggle, is provided that can include an anterior module (such as a lens support) and an interchangeable posterior module (such as a faceplate). The anterior module can be adapted to support at least one lens in a wearer's field of view. The posterior module can be adapted to fit against a contour of the wearer's face and can be selectively interchangeable with the anterior module to modify at least one physical characteristic of the eyewear. In some embodiments, the anterior and posterior modules can be coupled by a suspension assembly in order to allow articulation of the posterior module relative to the anterior module for evenly distributing forces against the wearer's face. Further, the anterior module can be rigid for maintaining the lens in an optically-desirable orientation. Furthermore, the goggle can comprise an interchangeable lens mechanism to facilitate interchanging of lenses in the goggle.
Abstract translation: 提供眼镜,例如护目镜,其可以包括前模块(例如透镜支架)和可互换的后模块(例如面板)。 前模块可以适于在佩戴者的视野中支撑至少一个透镜。 后模块可以适于与佩戴者的脸部轮廓相配合,并且可以与前模块选择性地互换,以修改眼镜的至少一个物理特性。 在一些实施例中,前部和后部模块可以通过悬挂组件联接,以便允许后部模块相对于前部模块铰接,以均匀地分配力抵抗穿着者的脸部。 此外,前模块可以是刚性的,用于将透镜保持在光学上期望的取向。 此外,护目镜可以包括可互换的透镜机构,以便于透镜在护目镜中的互换。
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公开(公告)号:US20140142083A1
公开(公告)日:2014-05-22
申请号:US14110873
申请日:2012-04-13
Applicant: Kevin Wayne Kuntz , Richard Chesworth , Kenneth William Duncan , Heike Keilhack , Natalie Warholic , Christine Klaus , Sarah K. Knutson , Timothy James Nelson Wigle , Masashi Seki
Inventor: Kevin Wayne Kuntz , Richard Chesworth , Kenneth William Duncan , Heike Keilhack , Natalie Warholic , Christine Klaus , Sarah K. Knutson , Timothy James Nelson Wigle , Masashi Seki
IPC: C07D405/14 , C07D401/14 , C07D213/64 , C07D401/12 , C07D405/12
CPC classification number: C07D213/64 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D407/12 , C07D409/12 , C07D413/12 , C07D413/14 , C07D491/048 , C07D491/08 , C07D491/10 , C07D491/113
Abstract: The present invention relates to substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
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公开(公告)号:US20130040906A1
公开(公告)日:2013-02-14
申请号:US13418242
申请日:2012-03-12
Applicant: Kevin W. Kuntz , Sarah K. Knutson , Timothy James Nelson Wigle
Inventor: Kevin W. Kuntz , Sarah K. Knutson , Timothy James Nelson Wigle
CPC classification number: A61K31/5377 , A61K31/4412 , A61K31/4427 , A61K31/4439 , A61K31/444 , A61K31/4545 , A61K31/496 , A61K31/497 , A61K31/551 , A61K31/7076 , A61K31/711 , A61K38/17 , C07D405/12 , C07D473/34 , C12Q1/48 , C12Q1/68 , G01N33/5011 , G01N33/57426 , G01N2333/91011 , G01N2333/91017 , G01N2800/52 , Y10T436/143333
Abstract: The invention relates to inhibition of wild-type and certain mutant forms of human histone methyltransferase EZH2, the catalytic subunit of the PRC2 complex which catalyzes the mono- through tri-methylation of lysine 27 on histone H3 (H3-K27). In one embodiment the inhibition is selective for the mutant form of the EZH2, such that trimethylation of H3-K27, which is associated with certain cancers, is inhibited. The methods can be used to treat cancers including follicular lymphoma and diffuse large B-cell lymphoma (DLBCL). Also provided are methods for identifying small molecule selective inhibitors of the mutant forms of EZH2 and also methods for determining responsiveness to an EZH2 inhibitor in a subject.
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公开(公告)号:US20130034672A1
公开(公告)日:2013-02-07
申请号:US13204471
申请日:2011-08-05
Applicant: James Nelson Aldrich, III , Benjamin Michael Finney , Paul John Kudrna , Peter P. Kosanovich
Inventor: James Nelson Aldrich, III , Benjamin Michael Finney , Paul John Kudrna , Peter P. Kosanovich
CPC classification number: H04M1/0283 , Y10T29/49826
Abstract: A translucent or transparent cover plate has an inner side and an outer side. A decoration portion bearing a decoration or art work is attached to the inner side of the cover plate. The decoration or art work is visible through the outer side of cover plate. Retention features can be attached or joined to the cover plate to enable the cover plate to be attached to an electronic device.
Abstract translation: 半透明或透明的盖板具有内侧和外侧。 承载装饰或艺术品的装饰部分附着在盖板的内侧。 装饰或艺术作品通过盖板的外侧是可见的。 保持特征可以附接或接合到盖板,以使盖板能够附接到电子设备。
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公开(公告)号:US20120019626A1
公开(公告)日:2012-01-26
申请号:US13172686
申请日:2011-06-29
Applicant: Zhen Hou , James Jianguo Xu , Ken Kinsun Lee , James Nelson Stainton , Hung Phi Nguyen , Rusmin Kudinar , Ronny Soetarman
Inventor: Zhen Hou , James Jianguo Xu , Ken Kinsun Lee , James Nelson Stainton , Hung Phi Nguyen , Rusmin Kudinar , Ronny Soetarman
CPC classification number: G02B21/006 , G01N21/9501 , G01N21/956 , G01N2021/0168 , G02B21/0016 , G02B21/0028 , G02B21/0032 , G02B21/367 , G06T7/60 , G06T2207/10056 , G06T2207/10152 , G06T2207/20068 , G06T2207/30148
Abstract: A three-dimensional (3D) microscope for patterned substrate measurement can include an objective lens, a reflected illuminator, a transmitted illuminator, a focusing adjustment device, an optical sensor, and a processor. The focusing adjustment device can automatically adjust the objective lens focus at a plurality of Z steps. The optical sensor can be capable of acquiring images at each of these Z steps. The processor can control the reflected illuminator, the transmitted illuminator, the focusing adjustment device, and the optical sensor. The processor can be configured to capture first and second images at multiple Z steps, the first image with the pattern using the reflected illuminator and the second image without the pattern using one of the reflected illuminator and the transmitted illuminator.
Abstract translation: 用于图案化衬底测量的三维(3D)显微镜可以包括物镜,反射照明器,透射照明器,聚焦调节装置,光学传感器和处理器。 聚焦调节装置可以在多个Z步骤自动调节物镜焦点。 光学传感器能够在这些Z步骤的每个步骤中获取图像。 处理器可以控制反射照明器,透射照明器,聚焦调节装置和光学传感器。 处理器可以被配置成以多个Z步骤捕获第一和第二图像,第一图像使用反射照明器的图案,而不使用反射照明器和透射照明器之一的图案的第二图像。
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