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    SYSTEM FOR DETECTION OF A TARGET ANALYTE VIA SELF-TESTING, OBJECT SURFACES, AND THE ENVIRONMENT
    3.
    发明申请
    SYSTEM FOR DETECTION OF A TARGET ANALYTE VIA SELF-TESTING, OBJECT SURFACES, AND THE ENVIRONMENT 有权

    公开(公告)号：US20250146947A1

    公开(公告)日：2025-05-08

    申请号：US18740134

    申请日：2024-06-11

    Applicant: LogicInk Corporation

    Inventor： Carlos Edel OLGUIN ALVAREZ ,  Steven WROBEL ,  Hendrik DIETZ

    IPC: G01N21/78 ,  G01N21/27 ,  G01N21/77 ,  G01N27/414

    Abstract: Systems and indicators for determining the presence or absence of specific environmental, exposure, or biological conditions are provided. Indicators include a plurality of sensors, each sensor independently having a biological or chemical sensing modality to detect one or more analytes of interest. Analytes of interest include nucleic acids (e.g., DNA, RNA, etc.), proteins, peptides, and other amino acid chains and may come from a subject or the microbiome of a subject. The signals from the plurality of sensors may be processed to provide a readily understandable readout concerning a health condition or predisposition of a subject, such as cancer and exposure to coronavirus. The signals from the plurality of sensors may be colorimetric (e.g. a color change in response to the presence or absence of an analyte), and a plurality of colorimetric signals may be combined to provide a readily understandable colorimetric output. Indicators may be wearable.

    MOLECULAR BEACONS
    5.
    发明公开
    MOLECULAR BEACONS 审中-公开

    公开(公告)号：US20240018607A1

    公开(公告)日：2024-01-18

    申请号：US18252869

    申请日：2021-11-12

    Applicant: LogicInk Corporation

    Inventor： Carlos Edel OLGUIN ALVAREZ ,  Hendrik DIETZ ,  Steven WROBEL

    IPC: C12Q1/6897 ,  C12Q1/44

    CPC classification number: C12Q1/6897 ,  C12Q1/44

    Abstract: Systems comprising a translation module, an amplification module comprising one or more sensing modalities, and a detection module configured to accept the amplifier output and methods of using the same are provided. The systems or methods can be capable of detecting trace amounts of nucleic acid molecules with high sensitivity and specificity in a device-free system with naked-eye readable output. The systems can comprise three layers incorporated into a lateral flow assay and/or a paper strip assay, in such systems, the first layer can comprise the translation module, the second layer can comprise the amplification module, and the third layer can comprise the detection module.

    CUMULATIVE BIOSENSOR SYSTEM TO DETECT ALCOHOL
    6.
    发明申请
    CUMULATIVE BIOSENSOR SYSTEM TO DETECT ALCOHOL 审中-公开

    公开(公告)号：US20200022648A1

    公开(公告)日：2020-01-23

    申请号：US16528362

    申请日：2019-07-31

    Applicant: LOGICINK CORPORATION

    Inventor： Tal Danino ,  Ian Fritz ,  Carlos Olguin ,  Skylar Tibbits ,  Marcelo Coelho

    IPC: A61B5/00 ,  A61B5/145

    Abstract: A wearable device may be provided for detecting cumulative alcohol consumption. Such a wearable device may include an adhesive layer that adheres to skin and that allows sweat from the skin to pass through and a customizable ink layer that reacts irreversibly to change color along a gradient as ethanol is detected in the sweat. The customizable ink continues to increase color intensity along the gradient as ethanol continues to be detected in the sweat over time.

    Communication using programmable materials
    7.
    发明授权
    Communication using programmable materials 有权

    公开(公告)号：US11331040B2

    公开(公告)日：2022-05-17

    申请号：US15451065

    申请日：2017-03-06

    Applicant: Logicink Corporation

    Inventor： Carlos Edel Olguin Alvarez ,  Skylar Jackson Eagle Tibbits ,  Marcelo Henrique Coelho ,  Tal Danino

    IPC: A61B5/00 ,  G01N27/327 ,  A61B5/145

    Abstract: A dynamic sensor interface is provided. Such a dynamic sensor interface may include a reaction portion that includes a biological-based or chemical-based ink. Such ink reacts in response to a molecule of interest. The dynamic sensor interface may further include an electrode that detects the reaction by the ink in response to the molecule of interest, as well as a signal interface that emits a signal based on the electrode detecting the reaction. Such a dynamic sensor interface allows for information to be detected and communicated through and between both bio-chemical and electronic systems.

    SYSTEM FOR DETECTION OF A TARGET ANALYTE VIA SELF-TESTING, OBJECT SURFACES, AND THE ENVIRONMENT
    8.
    发明申请
    SYSTEM FOR DETECTION OF A TARGET ANALYTE VIA SELF-TESTING, OBJECT SURFACES, AND THE ENVIRONMENT 有权

    公开(公告)号：US20210333214A1

    公开(公告)日：2021-10-28

    申请号：US17219527

    申请日：2021-03-31

    Applicant: LogicInk Corporation

    Inventor： Carlos Edel OLGUIN ALVAREZ ,  Steven WROBEL ,  Hendrik DIETZ

    IPC: G01N21/78 ,  G01N27/414 ,  G01N21/27

    Abstract: Systems and indicators for determining the presence or absence of specific environmental, exposure, or biological conditions are provided. Indicators include a plurality of sensors, each sensor independently having a biological or chemical sensing modality to detect one or more analytes of interest. Analytes of interest include nucleic acids (e.g., DNA, RNA, etc.), proteins, peptides, and other amino acid chains and may come from a subject or the microbiome of a subject. The signals from the plurality of sensors may be processed to provide a readily understandable readout concerning a health condition or predisposition of a subject, such as cancer and exposure to coronavirus. The signals from the plurality of sensors may be colorimetric (e.g. a color change in response to the presence or absence of an analyte), and a plurality of colorimetric signals may be combined to provide a readily understandable colorimetric output. Indicators may be wearable.

    MULTI-SENSING OF NUCLEIC ACID AND SMALL MOLECULE MARKERS
    10.
    发明公开
    MULTI-SENSING OF NUCLEIC ACID AND SMALL MOLECULE MARKERS 审中-公开

    公开(公告)号：US20230212702A1

    公开(公告)日：2023-07-06

    申请号：US18000615

    申请日：2021-06-04

    Applicant: LogicInk Corporation

    Inventor： Hendrik DIETZ ,  Carlos Edel OLGUIN ALVAREZ

    IPC: C12Q1/70 ,  C12Q1/6818

    CPC classification number: C12Q1/701 ,  C12Q1/6818

    Abstract: Systems and methods for determining the presence or absence of an analyte including a nucleic acid (e.g., DNA and RNA), a small molecule (e.g., proteins and amino acid chains), and one or more electrolytes (e.g., Na+ and K+). The system or method may detect multiple analytes (e.g., a first DNA and a second DNA) and/or multiple types of analytes (e.g., an RNA and an antibody protein). The signal readout provided by the system or method may be readily understood and may be correlated with a health condition (e.g., hydration or exposure to an infectious agent). The system may be wearable and may analyze one or more biofluids.

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