公开(公告)号：US20190350708A1

公开(公告)日：2019-11-21

申请号：US16526843

申请日：2019-07-30

Applicant: Mark L. MATHIS ,  Gregory D. NIEMINEN ,  Nathan ARONSON ,  Garrett R. BEGET

Inventor： Mark L. MATHIS ,  Gregory D. NIEMINEN ,  Nathan ARONSON ,  Garrett R. BEGET

IPC: A61F2/24

Abstract: An intravascular support device includes a support or reshaper wire, a proximal anchor and a distal anchor. The support wire engages a vessel wall to change the shape of tissue adjacent the vessel in which the intravascular support is placed. The anchors and support wire are designed such that the vessel in which the support is placed remains open and can be accessed by other devices if necessary. The device provides a minimal metal surface area to blood flowing within the vessel to limit the creation of thrombosis. The anchors can be locked in place to secure the support within the vessel.

公开(公告)号：US20190336290A1

公开(公告)日：2019-11-07

申请号：US16450686

申请日：2019-06-24

Applicant: Mark L. MATHIS ,  Gregory D. NIEMINEN ,  David G. REUTER

Inventor： Mark L. MATHIS ,  Gregory D. NIEMINEN ,  David G. REUTER

IPC: A61F2/24

Abstract: Devices for treating mitral valve regurgitation, including a distal expandable anchor, a proximal expandable anchor, and a fixed length connecting member extending from the proximal expandable anchor to the distal expandable anchor, where at least one of the proximal and distal anchors includes first and second arm segments that extend from one end of the device toward the connecting member and the other anchor when in a collapsed delivery configuration, and where the at least one of the proximal and distal anchors that comprises the first and second arm segments has an expanded configuration in which the first and second arm segments extend radially outwardly such that the first and second arm segments extend away from one another toward the connector, and meet one another at a location axially spaced from the end of the device.

公开(公告)号：US20160374806A1

公开(公告)日：2016-12-29

申请号：US15261549

申请日：2016-09-09

Applicant: Mark L. MATHIS ,  Gregory D. NIEMINEN ,  David G. REUTER

Inventor： Mark L. MATHIS ,  Gregory D. NIEMINEN ,  David G. REUTER

IPC: A61F2/24

CPC classification number: A61F2/2451 ,  A61B2017/00243 ,  A61F2/24 ,  A61F2/2442 ,  A61F2/2466 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2250/0012 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61N1/057 ,  A61N2001/0585

Abstract: Devices for treating mitral valve regurgitation, including a distal expandable anchor, a proximal expandable anchor, and a fixed length connecting member extending from the proximal expandable anchor to the distal expandable anchor, where at least one of the proximal and distal anchors includes first and second arm segments that extend from one end of the device toward the connecting member and the other anchor when in a collapsed delivery configuration, and where the at least one of the proximal and distal anchors that comprises the first and second arm segments has an expanded configuration in which the first and second arm segments extend radially outwardly such that the first and second arm segments extend away from one another toward the connector, and meet one another at a location axially spaced from the end of the device.

公开(公告)号：US20160338832A1

公开(公告)日：2016-11-24

申请号：US15230060

申请日：2016-08-05

Applicant: Mark L. MATHIS ,  Gregory D. NIEMINEN ,  David G. REUTER

Inventor： Mark L. MATHIS ,  Gregory D. NIEMINEN ,  David G. REUTER

IPC: A61F2/24

CPC classification number: A61F2/2451 ,  A61B2017/00243 ,  A61F2/24 ,  A61F2/2442 ,  A61F2/2466 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2250/0012 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61N1/057 ,  A61N2001/0585

Abstract: Methods of treating mitral valve regurgitation, including causing a distal expandable anchor to self-expand within a coronary sinus, anchoring the distal expandable anchor against movement in the coronary sinus, changing the geometry of a mitral valve annulus, causing a proximal expandable anchor to self-expand within the coronary sinus, anchoring the proximal expandable anchor against movement within the coronary sinus, and withdrawing the delivery system from the coronary sinus.

Abstract translation: 治疗二尖瓣关闭不全的方法，包括使远端可扩张锚固体在冠状窦内自扩张，将远端可扩张锚定件抵靠在冠状窦内运动，改变二尖瓣环的几何形状，使近端可扩张锚自体 在冠状窦内扩张，使近端可扩张锚定件抵抗冠状窦内的运动，并从冠状窦取出输送系统。

公开(公告)号：US20130103059A1

公开(公告)日：2013-04-25

申请号：US13618902

申请日：2012-09-14

Applicant: Mark L. Mathis ,  David Thompson ,  Patrick Wu

Inventor： Mark L. Mathis ,  David Thompson ,  Patrick Wu

IPC: A61B19/00

CPC classification number: A61B17/12104 ,  A61B5/087 ,  A61B5/091 ,  A61B5/14542 ,  A61B5/4848 ,  A61B6/032 ,  A61B17/12022 ,  A61B17/12131 ,  A61B17/1214 ,  A61B17/12145 ,  A61B17/12172 ,  A61B17/1285 ,  A61B17/24 ,  A61B90/00 ,  A61B2017/00477 ,  A61B2017/00809 ,  A61B2017/12054 ,  A61B2034/108 ,  A61B2090/061 ,  A61B2090/3966 ,  A61M16/04 ,  A61M16/0406 ,  A61M16/0833 ,  A61M2205/0266

Abstract: A lung volume reduction system is disclosed comprising an implantable device adapted to be delivered to a lung airway of a patient in a delivery configuration and to change to a deployed configuration to bend the lung airway. The invention also discloses a method of bending a lung airway of a patient comprising inserting a device into the airway in a delivery configuration and bending the device into a deployed configuration, thereby bending the airway.

Abstract translation: 公开了一种肺容积减小系统，其包括可植入装置，其适于以递送配置递送到患者的肺气道并且改变为展开的配置以弯曲肺气道。 本发明还公开了一种弯曲患者的肺气道的方法，包括将装置以输送构造插入气道并将装置弯曲成展开构型，从而弯曲气道。

公开(公告)号：US20130096603A1

公开(公告)日：2013-04-18

申请号：US13618822

申请日：2012-09-14

Applicant: Mark L. Mathis ,  David Thompson ,  Nathan Aronson ,  Patrick Wu

Inventor： Mark L. Mathis ,  David Thompson ,  Nathan Aronson ,  Patrick Wu

IPC: A61M16/20

CPC classification number: A61B17/12104 ,  A61B1/2676 ,  A61B17/12022 ,  A61B17/12031 ,  A61B17/12131 ,  A61B17/12145 ,  A61B17/12172 ,  A61B17/122 ,  A61B2017/00477 ,  A61B2017/00809 ,  A61B2017/1205 ,  A61B2017/12054 ,  A61F2/04 ,  A61F2002/043 ,  A61M16/04 ,  A61M16/0406 ,  A61M16/208 ,  A61M2205/0266

Abstract: The invention provides improved medical devices, therapeutic treatment systems, and treatment methods for treatment of the lung. A lung volume reduction system includes an implantable device having an elongate body that is sized and shaped for delivery via the airway system to a lung airway of a patient. The implant is inserted and positioned while the implant is in a delivery configuration, and is reconfigured to a deployed configuration so as to locally compress adjacent tissue of the lung, with portions of the elongate body generally moving laterally within the airway so as to laterally compress lung tissue. A plurality of such implants will often be used to treat a lung of a patient.

公开(公告)号：US08142455B2

公开(公告)日：2012-03-27

申请号：US12209631

申请日：2008-09-12

Applicant: David Thompson ,  Patrick Wu ,  David Lehrberg ,  Mark L. Mathis ,  Michael Boutillette

Inventor： David Thompson ,  Patrick Wu ,  David Lehrberg ,  Mark L. Mathis ,  Michael Boutillette

IPC: A61B17/08

CPC classification number: A61M16/208 ,  A61B1/018 ,  A61B1/04 ,  A61B1/2676 ,  A61B5/06 ,  A61B6/032 ,  A61B6/12 ,  A61B6/485 ,  A61B17/00234 ,  A61B17/12022 ,  A61B17/12031 ,  A61B17/12104 ,  A61B17/12131 ,  A61B17/1214 ,  A61B17/12145 ,  A61B17/1215 ,  A61B17/12172 ,  A61B90/00 ,  A61B90/02 ,  A61B2017/00477 ,  A61B2017/00809 ,  A61B2017/00867 ,  A61B2017/12054 ,  A61F2/04 ,  A61F2002/043 ,  A61F2002/046 ,  A61M16/04 ,  A61M16/0406 ,  A61M16/0833 ,  A61M37/0069 ,  A61M2205/0266 ,  A61M2205/32

Abstract: A lung volume reduction system is disclosed comprising an implantable device adapted to be delivered to a lung airway of a patient in a delivery configuration and to change to a deployed configuration to bend the lung airway. The invention also discloses a method of bending a lung airway of a patient comprising inserting a device into the airway in a delivery configuration and bending the device into a deployed configuration, thereby bending the airway.

Abstract translation: 公开了一种肺容积减小系统，其包括可植入装置，其适于以递送配置递送到患者的肺气道并且改变为展开的配置以弯曲肺气道。 本发明还公开了一种弯曲患者的肺气道的方法，包括将装置以输送构造插入气道并将装置弯曲成展开构型，从而弯曲气道。

公开(公告)号：US08075608B2

公开(公告)日：2011-12-13

申请号：US11971174

申请日：2008-01-08

Applicant: Lucas S. Gordon ,  Mark L. Mathis ,  Gregory Nieminen

Inventor： Lucas S. Gordon ,  Mark L. Mathis ,  Gregory Nieminen

IPC: A61F2/06

CPC classification number: A61F2/95 ,  A61B17/3468 ,  A61B2017/1205 ,  A61F2002/9511

Abstract: A system for selectively deploying a medical device includes a cartridge that is engageable with a proximal end of a delivery catheter that is routed to a desired location in a patient's body. An advancement mechanism is provided for advancing the medical device out of the cartridge and into the delivery catheter for deploying the medical device at the desired location in the patient's body.

Abstract translation: 用于选择性地部署医疗装置的系统包括可与输送导管的近端接合的药筒，所述输送导管被路由到患者体内的期望位置。 提供了一种推进机构，用于将医疗装置推出药筒并进入输送导管，以将医疗装置展开在病人身体的所需位置。

公开(公告)号：US07503931B2

公开(公告)日：2009-03-17

申请号：US11234809

申请日：2005-09-23

Applicant: Leonard Kowalsky ,  Gregory D. Nieminen ,  Ryan H. Braxtan ,  Mark L. Mathis

Inventor： Leonard Kowalsky ,  Gregory D. Nieminen ,  Ryan H. Braxtan ,  Mark L. Mathis

IPC: A61F2/24

CPC classification number: A61F2/2451

Abstract: An assembly for effecting the condition of a mitral valve annulus includes a mitral valve therapy device, a coupling structure carried by the device, a catheter, a second coupling structure, and a locking member. To implant the device, the device is first releasably locked to a pushing member by the coupling structures and the locking member. When the device is positioned within the coronary sinus adjacent the mitral valve annulus and deployed, the coupling structures may be released from each other by the release of the locking member.

Abstract translation: 用于实现二尖瓣环的状态的组件包括二尖瓣治疗装置，由装置承载的联接结构，导管，第二联接结构和锁定构件。 为了植入装置，装置首先通过联接结构和锁定构件可释放地锁定到推动构件。 当装置定位在邻近二尖瓣环并展开的冠状窦内时，联接结构可以通过释放锁定构件而相互释放。

公开(公告)号：US07452375B2

公开(公告)日：2008-11-18

申请号：US10994168

申请日：2004-11-19

Applicant: Mark L. Mathis ,  Leonard Kowalsky ,  David G. Reuter ,  Cruz Beeson

Inventor： Mark L. Mathis ,  Leonard Kowalsky ,  David G. Reuter ,  Cruz Beeson

IPC: A61F2/24

CPC classification number: A61F2/2451 ,  A61F2/2466 ,  A61F2002/91591 ,  A61F2210/0014 ,  A61F2220/0091 ,  A61F2230/0023 ,  A61F2250/0004 ,  A61F2250/0008 ,  A61F2250/0012 ,  A61F2250/0086 ,  A61F2310/00017 ,  A61F2310/00023

Abstract: An anchor anchors a therapeutic device having an elongated body within a body lumen. The anchor includes a fixation member carried on the device which is adjustable from a first configuration that permits placement of the device in the body lumen to a second configuration that anchors the device within the body lumen. The anchor further includes a lock that locks the fixation member in the second configuration. The fixation member may be locked in any one of a plurality of intermediate points between the first configuration and a maximum second configuration.

Abstract translation: 锚定器将具有细长体的治疗装置锚定在体腔内。 所述锚固件包括承载在所述装置上的固定构件，所述固定构件可从第一构造调节，所述第一构型允许将所述装置放置在所述体腔内到达将所述装置固定在所述体腔内的第二构造。 锚固件还包括将固定构件锁定在第二构造中的锁。 固定构件可以锁定在第一构造和最大第二构造之间的多个中间点中的任何一个中。