公开(公告)号：US20250122545A1

公开(公告)日：2025-04-17

申请号：US18988591

申请日：2024-12-19

Applicant: Novozymes, Inc.

Inventor： Brett McBrayer ,  Elena Vlasenko ,  Tarana Shaghasi

IPC: C12P19/14 ,  C12N1/22 ,  C12N9/24 ,  C12N9/42 ,  C12P19/02 ,  C12P19/12 ,  C12P21/02

Abstract: The present invention relates to enzyme compositions for high temperature saccharification of cellulosic material and to uses thereof.

公开(公告)号：US20220307002A1

公开(公告)日：2022-09-29

申请号：US17714461

申请日：2022-04-06

Applicant: Novozymes, Inc.

Inventor： Janine Lin ,  Doreen Bohan ,  Michelle Maranta ,  Leslie DeMars ,  Michael Lamsa ,  Matt Sweeny ,  Mark David Wogulis ,  Elizabeth Znameroski ,  Frank Winther Rasmussen

IPC: C12N9/42 ,  C12N9/02 ,  D21C5/00 ,  D21H17/00 ,  C11D3/386 ,  C12P19/02 ,  C12P19/14

Abstract: The present invention relates to GH61 polypeptide variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

公开(公告)号：US11427847B2

公开(公告)日：2022-08-30

申请号：US17163033

申请日：2021-01-29

Applicant: Novozymes, Inc.

Inventor： Suchindra Maiyuran ,  Abigail Jang ,  Kimberly Brown ,  Sandra Merino ,  Jeffrey Shasky ,  Eric Abbate

IPC: C12P21/00 ,  C12N15/80 ,  C12P21/02 ,  C12N15/04 ,  C12N9/58

Abstract: The present invention relates to mutants of a parent Trichoderma strain, comprising a polynucleotide encoding a polypeptide and one or more (several) genes selected from the group consisting of a first subtilisin-like serine protease gene, a first aspartic protease gene, a trypsin-like serine protease gene, a second subtilisin-like serine protease gene, and a second aspartic protease gene, wherein the one or more (several) genes are modified rendering the mutant strain deficient in the production of one or more (several) enzymes selected from the group consisting of a first subtilisin-like serine protease, a first aspartic protease, a trypsin-like serine protease, a second subtilisin-like serine protease, and a second aspartic protease, respectively, compared to the parent Trichoderma strain when cultivated under identical conditions. The present invention also relates to methods of producing a polypeptide in such mutants and methods for producing such mutants.

公开(公告)号：US11203746B2

公开(公告)日：2021-12-21

申请号：US16211604

申请日：2018-12-06

Applicant: Novozymes, Inc.

Inventor： Marc D. Morant ,  Paul Harris

IPC: C12P7/02 ,  C12P13/04 ,  C12P7/26 ,  C12P7/40 ,  C12P5/00 ,  C12P19/14 ,  C12N9/24 ,  C12N9/42 ,  C12P21/00 ,  C12P19/02 ,  C12P7/14

Abstract: The present invention relates to isolated polypeptides having cellobiohydrolase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.

公开(公告)号：US20210363558A1

公开(公告)日：2021-11-25

申请号：US17372667

申请日：2021-07-12

Applicant: NOVOZYMES, INC.

Inventor： Brett McBrayer ,  Tarana Shaghasi ,  Elena Vlasenko

IPC: C12P19/14 ,  C12N1/22 ,  C12N9/42 ,  C12P19/02 ,  C12N9/24 ,  C12P19/12 ,  C12P21/02

Abstract: The present invention relates to enzyme compositions for high temperature saccharification of cellulosic material and to uses thereof.

公开(公告)号：US11098290B2

公开(公告)日：2021-08-24

申请号：US16589796

申请日：2019-10-01

Applicant: Novozymes A/S ,  Novozymes, Inc.

Inventor： Kirk Schnorr ,  Tarana Shaghasi

IPC: C12N9/24 ,  C12P19/14 ,  C12P21/00 ,  C12P7/10 ,  C12N9/42 ,  C12N15/113 ,  C12N9/02

Abstract: The present invention relates to isolated polypeptides having cellulolytic enhancing activity and polynucleotides encoding the polypeptides, catalytic domains, cellulose binding domains and polynucleotides encoding the polypeptides, catalytic domains or cellulose binding domains. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or cellulose binding domains.

公开(公告)号：US11091785B2

公开(公告)日：2021-08-17

申请号：US16840012

申请日：2020-04-03

Applicant: Novozymes, Inc.

Inventor： Brett McBrayer ,  Tarana Shaghasi ,  Elena Vlasenko

IPC: C12P19/14 ,  C12N1/22 ,  C12N9/42 ,  C12P19/02 ,  C12N9/24 ,  C12P19/12 ,  C12P21/02

Abstract: The present invention relates to enzyme compositions for high temperature saccharification of cellulosic material and to uses thereof.

公开(公告)号：US11078508B2

公开(公告)日：2021-08-03

申请号：US16211632

申请日：2018-12-06

Applicant: Novozymes, Inc.

Inventor： Suchindra Maiyuran ,  Abigail Jang ,  Kimberly Brown ,  Sandra Merino ,  Jeffrey Shasky ,  Eric Abbate

IPC: C12P21/00 ,  C12P21/02 ,  C12N9/58 ,  C12N15/80 ,  C12N15/04

Abstract: The present invention relates to mutants of a parent Trichoderma strain, comprising a polynucleotide encoding a polypeptide and one or more (several) genes selected from the group consisting of a first subtilisin-like serine protease gene, a first aspartic protease gene, a trypsin-like serine protease gene, a second subtilisin-like serine protease gene, and a second aspartic protease gene, wherein the one or more (several) genes are modified rendering the mutant strain deficient in the production of one or more (several) enzymes selected from the group consisting of a first subtilisin-like serine protease, a first aspartic protease, a trypsin-like serine protease, a second subtilisin-like serine protease, and a second aspartic protease, respectively, compared to the parent Trichoderma strain when cultivated under identical conditions. The present invention also relates to methods of producing a polypeptide in such mutants and methods for producing such mutants.

公开(公告)号：US10883129B2

公开(公告)日：2021-01-05

申请号：US16539862

申请日：2019-08-13

Applicant: Novozymes, Inc.

Inventor： Kimberly Brown ,  Eric Abbate

IPC: C12N9/24 ,  C12P7/14 ,  C12P19/14 ,  C12N9/42 ,  C12P19/02

Abstract: The present invention relates to enzyme compositions comprising a polypeptide having cellobiohydrolase II activity, a polypeptide having xylanase activity, and one or more cellulolytic proteins and their use in the degradation or conversion of cellulosic material.

公开(公告)号：US10647972B2

公开(公告)日：2020-05-12

申请号：US16211689

申请日：2018-12-06

Applicant: Novozymes, Inc.

Inventor： Donna Moyer

IPC: C12N9/42 ,  C12N15/80 ,  C12N9/24

Abstract: The present invention relates to methods for obtaining positive transformants of a filamentous fungal host cell, comprising: transforming a tandem construct into a population of cells of the filamentous fungal host a tandem construct and isolating a transformant of the filamentous fungal host cell comprising the tandem construct. The present invention also relates to such tandem constructs, filamentous fungal host cells comprising such tandem constructs, and methods of producing multiple recombinant proteins.