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公开(公告)号:US20120208706A1
公开(公告)日:2012-08-16
申请号:US13339986
申请日:2011-12-29
Applicant: Sean R. Downing , Mirna Jarosz , Doron Lipson , Geoffrey Alan Otto , Alexander N. Parker , Mikhail G. Shapiro , Philip James Stephens , Roman Yelensky
Inventor: Sean R. Downing , Mirna Jarosz , Doron Lipson , Geoffrey Alan Otto , Alexander N. Parker , Mikhail G. Shapiro , Philip James Stephens , Roman Yelensky
CPC classification number: C12Q1/6827 , C12Q1/6874 , C12Q1/6886 , G06F19/18 , G06F19/22 , C12Q2537/143 , C12Q2537/149
Abstract: A method of analyzing a tumor sample comprising: (a) acquiring a library comprising a plurality of tumor members from a tumor sample; (b) contacting the library with a bait set to provide selected members; (c) acquiring a read for a subgenomic interval from a tumor member from said library; (d) aligning said read; and (e) assigning a nucleotide value (e.g., calling a mutation) from said read for the preselected nucleotide position, thereby analyzing said tumor sample.
Abstract translation: 一种分析肿瘤样品的方法,包括:(a)从肿瘤样品获得包含多个肿瘤成员的文库; (b)与图书馆联系以提供选定的成员; (c)从所述文库的肿瘤成员获取亚基因组间隔的读数; (d)对准所述阅读; 和(e)从预选核苷酸位置的所述读取中分配核苷酸值(例如调用突变),从而分析所述肿瘤样品。
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公开(公告)号:USD296132S
公开(公告)日:1988-06-07
申请号:US778928
申请日:1985-09-23
Applicant: Lucien R. Downing
Designer: Lucien R. Downing
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公开(公告)号:USD292316S
公开(公告)日:1987-10-13
申请号:US700723
申请日:1985-02-12
Applicant: Lucien R. Downing
Designer: Lucien R. Downing
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公开(公告)号:US4615440A
公开(公告)日:1986-10-07
申请号:US729270
申请日:1985-05-01
Applicant: Todd R. Downing
Inventor: Todd R. Downing
CPC classification number: F01L1/25 , Y10S206/82 , Y10T29/49876 , Y10T29/49895
Abstract: The invention includes a method of retaining, shipping and assembling tappet cartridge assemblies, as well as a plastic sleeve for retaining the tappet cartridge assembly during shipping and assembly. In the method, a plastic sleeve retains an otherwise removable plunger in a tappet cartridge assembly body. The thus-retained cartridge assembly may be shipped and during subsequent assembly is positioned in alignment with a tappet follower. The tappet cartridge assembly is pushed through the retainer plastic sleeve into the tappet follower with such movement releasing the cartridge assembly from the plastic sleeve, permitting removal of the plastic sleeve.
Abstract translation: 本发明包括保持,运输和组装挺杆筒组件的方法,以及用于在运输和组装期间保持挺杆筒组件的塑料套筒。 在该方法中,塑料套筒将另外可移动的柱塞保持在挺杆筒组件主体中。 这样保持的盒组件可以运输,并且在随后的组装期间定位成与挺杆从动件对准。 挺杆筒组件通过这种移动将保持器塑料套筒推入保持器塑料套筒中,从而将盒组件从塑料套筒释放,从而可以移除塑料套筒。
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公开(公告)号:US4585268A
公开(公告)日:1986-04-29
申请号:US660640
申请日:1984-10-15
Applicant: Terry R. Downing
Inventor: Terry R. Downing
CPC classification number: B66F9/07545
Abstract: An overhead guard is provided for counterweighted lift trucks of different lengths. The overhead guard has a top portion supported at its front end by a pair of laterally spaced front legs extending downwardly to attaching points on the front of the truck and the top portion is supported at its rear end by adjustably positioned laterally spaced rear posts. The top of the rear posts may be attached to different longitudinally spaced points on the upper portion of the guard and the bottom of the rear posts are attachable to support posts on the counterweight which is at different longitudinal positions on different length trucks.
Abstract translation: 为不同长度的配重起重车提供了架空防护罩。 顶部防护罩的顶端部分由一对侧向间隔开的前腿支撑在其前端,向下延伸到卡车前部的安装点,顶部部分通过可调节地定位的侧向间隔开的后支柱支撑在其后端。 后柱的顶部可以附接到护罩的上部上的不同的纵向间隔的点,并且后柱的底部可附接到配重上的支撑柱,该配重在不同长度的卡车上处于不同的纵向位置。
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公开(公告)号:USD259813S
公开(公告)日:1981-07-07
申请号:US7072
申请日:1979-01-29
Applicant: James R. Downing
Designer: James R. Downing
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公开(公告)号:US4067156A
公开(公告)日:1978-01-10
申请号:US648045
申请日:1976-01-12
Applicant: Lucien R. Downing, Jr.
Inventor: Lucien R. Downing, Jr.
IPC: E04F15/024 , E04B5/08 , E04C2/06
CPC classification number: E04F15/02405
Abstract: A panel for elevated access floors is disclosed in which the panel is formed of reinforced expanded lightweight concrete. The reinforcing is provided by a grid including two arrays of parallel reinforcing rods which extend parallel to the associated panel edges and perpendicular to the rods of the other grid. A frame is provided by the grid around the two arrays. The grid is located adjacent to the lower surface of the body and divides the body into a plurality of square zones. Located in each zone, excepting the zones at the corners, is a pyramid-shaped cavity which extends from a base at the lower surface of the panel upwardly at about 45.degree. to an apex spaced from the upper surface of the panel. The presence of the pyramid-shaped cavities does not materially reduce the strength of the panel when compared to a similar panel without such cavities, but reduces the weight of the panel and the material required to manufacture the panel.
Abstract translation: 公开了一种用于升高的通风地板的面板,其中面板由增强的膨胀轻质混凝土形成。 该加强件由包括两个平行的加强杆阵列的格栅提供,该平行的加强杆平行于相关的镶板边缘并垂直于另一个格栅的杆延伸。 一个框架由两个阵列周围的网格提供。 网格位于主体的下表面附近并将主体分成多个正方形区域。 位于每个区域中,除角落之外的区域是金字塔形的空腔,其从面板的下表面的基部向上延伸约45度至与面板的上表面间隔开的顶点。 与没有这种空腔的类似面板相比,金字塔形空腔的存在不会实质地降低面板的强度,但是减小了面板和制造面板所需的材料的重量。
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公开(公告)号:US09340830B2
公开(公告)日:2016-05-17
申请号:US13339986
申请日:2011-12-29
Applicant: Doron Lipson , Geoffrey Alan Otto , Alexander N. Parker , Philip James Stephens , Sean R. Downing , Mima Jarosz , Mikhail G. Shapiro , Roman Yelensky
Inventor: Doron Lipson , Geoffrey Alan Otto , Alexander N. Parker , Philip James Stephens , Sean R. Downing , Mima Jarosz , Mikhail G. Shapiro , Roman Yelensky
CPC classification number: C12Q1/6827 , C12Q1/6874 , C12Q1/6886 , G06F19/18 , G06F19/22 , C12Q2537/143 , C12Q2537/149
Abstract: A method of analyzing a tumor sample comprising: (a) acquiring a library comprising a plurality of tumor members from a tumor sample; (b) contacting the library with a bait set to provide selected members; (c) acquiring a read for a subgenomic interval from a tumor member from said library; (d) aligning said read; and (e) assigning a nucleotide value (e.g., calling a mutation) from said read for the preselected nucleotide position, thereby analyzing said tumor sample.
Abstract translation: 一种分析肿瘤样品的方法,包括:(a)从肿瘤样品获得包含多个肿瘤成员的文库; (b)与图书馆联系以提供选定的成员; (c)从所述文库的肿瘤成员获取亚基因组间隔的读数; (d)对准所述阅读; 和(e)从预选核苷酸位置的所述读取中分配核苷酸值(例如调用突变),从而分析所述肿瘤样品。
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公开(公告)号:US20140307309A1
公开(公告)日:2014-10-16
申请号:US14250553
申请日:2014-04-11
Applicant: Kevin R. Downing , Ian S. Tribick
Inventor: Kevin R. Downing , Ian S. Tribick
Abstract: Optical filter elements each include a parallelogram-shaped substrate with parallel light entrance and light exit surfaces and parallel slanted sidewalls slanted at an angle, and an interference filter disposed on one or both of the light entrance surface and the light exit surface. The optical filter elements are bonded together at the slanted sidewalls to form the optical filter array. Light is filtered by illuminating the optical filter array at an angle θ equal to or corresponding to the angle of the slanted sidewalls. In some embodiments the angle of the slanted sidewalls corresponds to the angle-of-incidence θ by Snell's law.
Abstract translation: 光学滤光元件各自包括平行四边形基板,其具有平行的光入射面和光出射面以及以一定角度倾斜的平行倾斜的侧壁,以及布置在光入射表面和光出射表面中的一个或两个上的干涉滤光器。 光学滤波器元件在倾斜侧壁处结合在一起以形成滤光器阵列。 通过以一定角度照射光学滤光器阵列来过滤光; 等于或对应于倾斜侧壁的角度。 在一些实施例中,倾斜侧壁的角度对应于入射角度; 通过斯内尔定律。
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公开(公告)号:US20140020163A1
公开(公告)日:2014-01-23
申请号:US13553048
申请日:2012-07-19
Applicant: Mark A. Stiles , James R. Downing
Inventor: Mark A. Stiles , James R. Downing
IPC: A41D13/05
CPC classification number: A41D13/0512 , A41D13/0568 , A42B3/0473 , A61F5/055
Abstract: A head and neck support (HANS) device comprises a yoke structure having a low collar, a left leg and a right leg extending respectively from a left side and a right side of the low collar, and a tether having a strap coupled to the low collar and a pair of catches connected to two ends of the strap. The low collar is characterized with a distance between a central line of the tether and a top end of each leg, where the distance is less than 70 mm. The catches of the tether are operable to attach to a helmet of the driver so as to engage the low collar with the helmet of the driver.
Abstract translation: 头颈支架(HANS)装置包括一个轭架结构,它具有一个低领,左脚和右腿,分别从低领的左侧和右侧延伸,以及一个系带, 衣领和一对连接到吊带两端的卡扣。 低领的特征在于系绳的中心线与每个腿的顶端之间的距离,其中距离小于70mm。 系绳的卡扣可操作以附接到驾驶员的头盔,以便将低领与驾驶员的头盔接合。
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