公开(公告)号：US20120059061A1

公开(公告)日：2012-03-08

申请号：US13202489

申请日：2010-02-19

Applicant: Makoto Arita ,  Hiroyuki Arai ,  Yousuke Isobe ,  Ryo Taguchi

Inventor： Makoto Arita ,  Hiroyuki Arai ,  Yousuke Isobe ,  Ryo Taguchi

IPC: A61K31/202 ,  C12P7/42 ,  A61P15/06 ,  A61P11/00 ,  A61P1/04 ,  A61P35/00 ,  C07C57/03 ,  A61P9/10

CPC classification number: C07C59/42 ,  C12P7/6427 ,  C12P7/6436

Abstract: An object of the present invention is to provide a compound having a novel structure for overcoming the defects of conventional steroid agents and NSAIDs. It is found that the particular dihydroxy bodies of eicosapentaenoic acid and docosahexaenoic acid, which have not conventionally been known (11,18-dihydroxy eicosapentaenoic acid (11,18-diHEPE), 17,18-dihydroxy eicosapentaenoic acid (17,18-diHEPE) etc.), have activity of inhibiting neutrophil, thereby solving the object. The present invention unexpectedly remarkably inhibits infiltration into a tissue of, and activation of neutrophil found out at acute inflammation. The compound of the present invention is a compound which has not conventionally been known. Therefore, utility as a new therapeutic is provided.

Abstract translation: 本发明的目的是提供一种具有克服常规类固醇剂和NSAID缺陷的新颖结构的化合物。 已经发现，二十碳五烯酸和二十二碳六烯酸的二羟基体通常不是已知的（11,18-二羟基二十碳五烯酸（11,18-diHEPE），17,18-二羟基二十碳五烯酸（17,18-diHEPE ）等）具有抑制嗜中性粒细胞的活性，从而解决了对象。 本发明意外地显着地抑制了在急性炎症中发现的组织和嗜中性粒细胞的活化。 本发明的化合物是通常未知的化合物。 因此，提供了作为新治疗剂的效用。

公开(公告)号：US20100332231A1

公开(公告)日：2010-12-30

申请号：US12791781

申请日：2010-06-01

Applicant: Mikio Nakano ,  Takashi Nose ,  Ryo Taguchi ,  Kotaro Funakoshi ,  Naoto Iwahashi

Inventor： Mikio Nakano ,  Takashi Nose ,  Ryo Taguchi ,  Kotaro Funakoshi ,  Naoto Iwahashi

IPC: G10L15/04

CPC classification number: G10L15/063 ,  G10L15/187

Abstract: A lexical acquisition apparatus includes: a phoneme recognition section 2 for preparing a phoneme sequence candidate from an inputted speech; a word matching section 3 for preparing a plurality of word sequences based on the phoneme sequence candidate; a discrimination section 4 for selecting, from among a plurality of word sequences, a word sequence having a high likelihood in a recognition result; an acquisition section 5 for acquiring a new word based on the word sequence selected by the discrimination section 4; a teaching word list 4A used to teach a name; and a probability model 4B of the teaching word and an unknown word, wherein the discrimination section 4 calculates, for each word sequence, a first evaluation value showing how much words in the word sequence correspond to teaching words in the list 4A and a second evaluation value showing a probability at which the words in the word sequence are adjacent to one another and selects a word sequence for which a sum of the first evaluation value and the second evaluation value is maximum, and wherein the acquisition section 5 acquires, as a new word, a word in the word sequence selected by the discrimination section that is not involved in the calculation of the first evaluation value.

Abstract translation: 词汇获取装置包括：音素识别部分2，用于从输入的语音中准备音素序列候选; 字符匹配部分3，用于基于音素序列候选来准备多个字序列; 鉴别部分4，用于从多个单词序列中选择识别结果中具有高可能性的单词序列; 获取部分5，用于基于由识别部分4选择的单词序列获取新单词; 用于教授名称的教学单词表4A; 以及教学词和未知词的概率模型4B，其中鉴别部分4针对每个单词序列计算第一评估值，其显示单词序列中多少单词​​对应于列表4A中的教学单词和第二评估 表示单词序列中的单词彼此相邻的概率的值，并且选择第一评价值和第二评价值的和为最大的单词序列，并且其中，获取单元5获取新的 字，由歧视部分选择的字序列中不涉及第一评估值的计算的单词。

公开(公告)号：US08566097B2

公开(公告)日：2013-10-22

申请号：US12791781

申请日：2010-06-01

Applicant: Mikio Nakano ,  Takashi Nose ,  Ryo Taguchi ,  Kotaro Funakoshi ,  Naoto Iwahashi

Inventor： Mikio Nakano ,  Takashi Nose ,  Ryo Taguchi ,  Kotaro Funakoshi ,  Naoto Iwahashi

IPC: G10L15/00

CPC classification number: G10L15/063 ,  G10L15/187

Abstract: A lexical acquisition apparatus includes: a phoneme recognition section 2 for preparing a phoneme sequence candidate from an inputted speech; a word matching section 3 for preparing a plurality of word sequences based on the phoneme sequence candidate; a discrimination section 4 for selecting, from among a plurality of word sequences, a word sequence having a high likelihood in a recognition result; an acquisition section 5 for acquiring a new word based on the word sequence selected by the discrimination section 4; a teaching word list 4A used to teach a name; and a probability model 4B of the teaching word and an unknown word, wherein the discrimination section 4 calculates, for each word sequence, a first evaluation value showing how much words in the word sequence correspond to teaching words in the list 4A and a second evaluation value showing a probability at which the words in the word sequence are adjacent to one another and selects a word sequence for which a sum of the first evaluation value and the second evaluation value is maximum, and wherein the acquisition section 5 acquires, as a new word, a word in the word sequence selected by the discrimination section that is not involved in the calculation of the first evaluation value.

Abstract translation: 词汇获取装置包括：音素识别部分2，用于从输入的语音中准备音素序列候选; 字符匹配部分3，用于基于音素序列候选来准备多个字序列; 鉴别部分4，用于从多个单词序列中选择识别结果中具有高可能性的单词序列; 获取部分5，用于基于由识别部分4选择的单词序列获取新单词; 用于教授名称的教学单词表4A; 以及教学词和未知词的概率模型4B，其中鉴别部分4针对每个单词序列计算第一评估值，其显示单词序列中多少单词​​对应于列表4A中的教学单词和第二评估 表示单词序列中的单词彼此相邻的概率的值，并且选择第一评价值和第二评价值的和为最大的单词序列，并且其中，获取单元5获取新的 字，由歧视部分选择的字序列中不涉及第一评估值的计算的单词。

公开(公告)号：US20050037238A1

公开(公告)日：2005-02-17

申请号：US10934555

申请日：2004-09-07

Applicant: Yasushi Sakai ,  Akihiro Ohtsuki ,  Keiji Ohkubo ,  Kazuo Enomoto ,  Sadayuki Watanabe ,  Takahiko Tamaki ,  Kiyoshi Kuga ,  Eiichi Miyashita ,  Ryo Taguchi

Inventor： Yasushi Sakai ,  Akihiro Ohtsuki ,  Keiji Ohkubo ,  Kazuo Enomoto ,  Sadayuki Watanabe ,  Takahiko Tamaki ,  Kiyoshi Kuga ,  Eiichi Miyashita ,  Ryo Taguchi

IPC: C23C14/14 ,  C23C14/34 ,  G11B5/64 ,  G11B5/667 ,  G11B5/73 ,  G11B5/851 ,  H01F10/13 ,  H01F41/18 ,  B05D5/12 ,  B05D1/36 ,  B05D3/08

CPC classification number: G11B5/667 ,  G11B5/7325 ,  G11B5/851

Abstract: The present invention provides a method for easily obtaining a perpendicular magnetic recording medium having the desired magnetic properties by sputtering, and a magnetic recording medium obtained by this method. The perpendicular magnetic recording medium of the present invention is a perpendicular magnetic recording medium comprising at least a soft magnetic underlayer, an underlayer, a magnetic recording layer, a protective layer, and a liquid lubricant layer sequentially laminated on a nonmagnetic substrate, wherein the magnetic recording layer is a rare earth-transition metal alloy amorphous film formed by sputtering, and the formation of the magnetic recording layer by sputtering is performed using a film-forming gas incorporating 2% or more, but 60% or less of an H2 gas. The present invention also discloses a method for producing the perpendicular magnetic recording medium.

Abstract translation: 本发明提供一种通过溅射容易地获得具有所需磁特性的垂直磁记录介质的方法和通过该方法获得的磁记录介质。 本发明的垂直磁记录介质是至少包括依次层压在非磁性基板上的软磁性底层，底层，磁记录层，保护层和液体润滑剂层的垂直磁记录介质，其中磁性 记录层是通过溅射形成的稀土 - 过渡金属合金非晶膜，并且通过溅射形成磁记录层是使用包含2％以上但60％以下的H 2气的成膜气体进行的。 本发明还公开了一种垂直磁记录介质的制造方法。

公开(公告)号：US08853437B2

公开(公告)日：2014-10-07

申请号：US13202489

申请日：2010-02-19

Applicant: Makoto Arita ,  Hiroyuki Arai ,  Yousuke Isobe ,  Ryo Taguchi

Inventor： Makoto Arita ,  Hiroyuki Arai ,  Yousuke Isobe ,  Ryo Taguchi

IPC: C07C59/42 ,  C07C233/09 ,  A61K31/16 ,  A61K31/11 ,  C07C291/00 ,  C12P7/64

CPC classification number: C07C59/42 ,  C12P7/6427 ,  C12P7/6436

Abstract: An object of the present invention is to provide a compound having a novel structure for overcoming the defects of conventional steroid agents and NSAIDs. It is found that the particular dihydroxy bodies of eicosapentaenoic acid and docosahexaenoic acid, which have not conventionally been known (11,18-dihydroxy eicosapentaenoic acid (11,18-diHEPE), 17,18-dihydroxy eicosapentaenoic acid (17,18-diHEPE) etc.), have activity of inhibiting neutrophil, thereby solving the object. The present invention unexpectedly remarkably inhibits infiltration into a tissue of, and activation of neutrophil found out at acute inflammation. The compound of the present invention is a compound which has not conventionally been known. Therefore, utility as a new therapeutic is provided.

Abstract translation: 本发明的目的是提供一种具有克服常规类固醇剂和NSAID缺陷的新颖结构的化合物。 已经发现，二十碳五烯酸和二十二碳六烯酸的二羟基体通常不是已知的（11,18-二羟基二十碳五烯酸（11,18-diHEPE），17,18-二羟基二十碳五烯酸（17,18-diHEPE ）等）具有抑制嗜中性粒细胞的活性，从而解决了对象。 本发明意外地显着地抑制了在急性炎症中发现的组织和嗜中性粒细胞的活化。 本发明的化合物是通常未知的化合物。 因此，提供了作为新治疗剂的效用。

公开(公告)号：US08532989B2

公开(公告)日：2013-09-10

申请号：US12874779

申请日：2010-09-02

Applicant: Kotaro Funakoshi ,  Mikio Nakano ,  Xiang Zuo ,  Naoto Iwahashi ,  Ryo Taguchi

Inventor： Kotaro Funakoshi ,  Mikio Nakano ,  Xiang Zuo ,  Naoto Iwahashi ,  Ryo Taguchi

IPC: G10L15/06

CPC classification number: G10L15/083 ,  G10L15/197

Abstract: A command recognition device includes: an utterance understanding unit that determines or selects word sequence information from speech information; speech confidence degree calculating unit that calculates degree of speech confidence based on the speech information and the word sequence information; a phrase confidence degree calculating unit that calculates a degree of phrase confidence based on image information and phrase information included in the word sequence information; and a motion control instructing unit that determines whether a command of the word sequence information should be executed based on the degree of speech confidence and the degree of phrase confidence.

Abstract translation: 命令识别装置包括：话音理解单元，其从语音信息确定或选择单词序列信息; 语音置信度计算单元，其基于所述语音信息和所述单词序列信息来计算语音置信度; 短语置信度计算单元，其基于包括在所述单词序列信息中的图像信息和短语信息来计算短语置信度; 以及运动控制指示单元，其基于语音置信度和短语置信度来确定是否应该执行字序列信息的命令。

公开(公告)号：US20110112839A1

公开(公告)日：2011-05-12

申请号：US12874779

申请日：2010-09-02

Applicant: Kotaro FUNAKOSHI ,  Mikio NAKANO ,  Xiang ZUO ,  Naoto IWAHASHI ,  Ryo TAGUCHI

Inventor： Kotaro FUNAKOSHI ,  Mikio NAKANO ,  Xiang ZUO ,  Naoto IWAHASHI ,  Ryo TAGUCHI

IPC: G10L15/00

CPC classification number: G10L15/083 ,  G10L15/197

Abstract: A command recognition device includes: an utterance understanding unit that determines or selects word sequence information from speech information; speech confidence degree calculating unit that calculates degree of speech confidence based on the speech information and the word sequence information; a phrase confidence degree calculating unit that calculates a degree of phrase confidence based on image information and phrase information included in the word sequence information; and a motion control instructing unit that determines whether a command of the word sequence information should be executed based on the degree of speech confidence and the degree of phrase confidence.

Abstract translation: 命令识别装置包括：话音理解单元，其从语音信息确定或选择单词序列信息; 语音置信度计算单元，其基于所述语音信息和所述单词序列信息来计算语音置信度; 短语置信度计算单元，其基于包括在所述单词序列信息中的图像信息和短语信息来计算短语置信度; 以及运动控制指示单元，其基于语音置信度和短语置信度来确定是否应该执行字序列信息的命令。