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公开(公告)号：US12214198B2
公开(公告)日：2025-02-04
申请号：US16132530
申请日：2018-09-17
Applicant: SPR Therapeutics, Inc.
Inventor： Maria E. Bennett , Joseph W. Boggs, II , Warren M. Gill , John Chae
Abstract: Embodiments of the present invention provide systems and methods for the treatment of pain through activation of select neural fibers. The neural fibers may comprise one or more afferent neural fibers and/or one or more efferent neural fibers. If afferent fibers are stimulated, alone or in combination with efferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate afferent pathways in a manner approximating natural afferent activity. The afferent fibers may be associated with primary receptors of muscle spindles, golgi tendon organs, secondary receptors of muscle spindles, joint receptors, touch receptors, and other types of mechanoreceptors and/or proprioceptors. If efferent fibers are stimulated, alone or in combination with afferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate intrafusal and/or extrafusal muscle fibers, which results in an indirect activation of afferent fibers associated therewith.
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公开(公告)号：US12194299B2
公开(公告)日：2025-01-14
申请号：US17824981
申请日：2022-05-26
Applicant: SPR Therapeutics, Inc.
Inventor： Maria E. Bennett , Joseph W. Boggs , Warren M. Grill , John Chae
IPC: A61N1/36
Abstract: Embodiments of the present invention provide systems and methods for the treatment of pain through activation of select neural fibers. The neural fibers may comprise one or more afferent neural fibers and/or one or more efferent neural fibers. If afferent fibers are stimulated, alone or in combination with efferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate afferent pathways in a manner approximating natural afferent activity. The afferent fibers may be associated with primary receptors of muscle spindles, golgi tendon organs, secondary, receptors of muscle spindles, joint receptors, touch receptors, and other types of mechanoreceptors and/or proprioceptors. If efferent fibers are stimulated, alone or in combination with afferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate intrafusal and/or extrafusal muscle fibers, which results in an indirect activation of afferent fibers associated therewith.
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公开(公告)号：US20240157156A1
公开(公告)日：2024-05-16
申请号：US18418456
申请日：2024-01-22
Applicant: SPR Therapeutics, Inc.
Inventor： Joseph W. Boggs , Amorn Wongsarnpigoon , Matthew G. deBock , Meredith J. McGee , Devin Sell , Robert B. Strother
CPC classification number: A61N1/37241 , A61B17/3403 , A61B17/3468 , A61N1/0456 , A61N1/0502 , A61N1/0558 , A61N1/36017 , A61N1/36071 , A61N1/36125 , A61N1/36142 , A61N1/37205 , A61N1/37247 , A61N1/37264 , A61B2017/3407 , A61B2017/3413 , A61B2017/3492
Abstract: An introducing device for locating a tissue region and deploying an electrode is shown and described. The introducing device may include an outer sheath. An inner sheath may be disposed within the outer sheath. The inner sheath may be configured to engage an implantable electrode. In an example, the inner sheath may comprise a stimulation probe having an uninsulated portion at or near a distal end of the delivery sheath. The outer sheath may be coupled to a power source or stimulation signal generating circuitry at a proximal end. A clinician may control application of the stimulation signal to a tissue region via the outer sheath.
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公开(公告)号：US20240024666A1
公开(公告)日：2024-01-25
申请号：US18035760
申请日：2022-11-17
Applicant: SPR Therapeutics, Inc.
Inventor： Joseph W. Boggs , Amorn WONGSARNPIGOON , Matthew G. DEBOCK , Meredith J. MCGEE , Devin SELL , Robert B. STROTHER , Joey GROSZEK , Nathan D. CROSBY
CPC classification number: A61N1/0558 , A61B17/3468 , A61N1/0502 , A61N1/37241
Abstract: An introducing device for locating a tissue region and deploying an electrode is shown and described. The introducing device may include an outer sheath. An inner sheath may be disposed within the outer sheath. The inner sheath may be configured to engage an implantable electrode. In an example, the inner sheath may comprise a stimulation probe having an uninsulated portion at or near a distal end of the delivery sheath. A sheath or needle may be coupled to a power source or stimulation signal generating circuitry at a proximal end. A clinician may control application of the stimulation signal to a tissue region via a sheath or needle.
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公开(公告)号：US11878176B2
公开(公告)日：2024-01-23
申请号：US17492091
申请日：2021-10-01
Applicant: SPR Therapeutics, Inc.
Inventor： Joseph W. Boggs , Amorn Wongsarnpigoon , Matthew G deBock , Meredith J. McGee , Devin Sell , Robert B. Strother
CPC classification number: A61N1/37241 , A61B17/3403 , A61B17/3468 , A61N1/0456 , A61N1/0502 , A61N1/0558 , A61N1/36017 , A61N1/36071 , A61N1/36125 , A61N1/36142 , A61N1/37205 , A61N1/37247 , A61N1/37264 , A61B2017/3407 , A61B2017/3413 , A61B2017/3492
Abstract: An introducing device for locating a tissue region and deploying an electrode is shown and described. The introducing device may include an outer sheath. An inner sheath may be disposed within the outer sheath. The inner sheath may be configured to engage an implantable electrode. In an example, the inner sheath may comprise a stimulation probe having an uninsulated portion at or near a distal end of the delivery sheath. The outer sheath may be coupled to a power source or stimulation signal generating circuitry at a proximal end. A clinician may control application of the stimulation signal to a tissue region via the outer sheath.
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Patent Agency Ranking
公开(公告)号：US11878164B2
公开(公告)日：2024-01-23
申请号：US16819301
申请日：2020-03-16
Applicant: SPR THERAPEUTICS, INC.
Inventor： Amorn Wongsarnpigoon , Maria E. Bennett , Joseph W. Boggs , John Chae , Michael F. Saulino
CPC classification number: A61N1/36021 , A61N1/0558 , A61N1/36071
Abstract: The present invention reduces pain and improves function long-term in persons with back pain using electrical stimulation in the back. This approach involves an electrical stimulation device including at least one electrode adapted for insertion within an animal body with back pain and at least one pulse generator operatively coupled with the at least one electrode, wherein the pulse generator delivers electrical stimulation activating at least one muscle in a back of the animal body for pain relief.
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公开(公告)号：US11745011B2
公开(公告)日：2023-09-05
申请号：US17458664
申请日：2021-08-27
Applicant: SPR Therapeutics, Inc.
Inventor： Joseph W. Boggs , Amorn Wongsarnpigoon , Matthew G. deBock , Meredith J. McGee , Devin Sell , Robert B. Strother
CPC classification number: A61N1/0558 , A61B17/3468 , A61N1/0502 , A61N1/0551 , A61N1/36017 , A61N1/36071 , A61N1/37205 , A61N1/3787 , A61N1/37211
Abstract: An introducing device for locating a tissue region and deploying an electrode is shown and described. The introducing device may include an outer sheath. An inner sheath may be disposed within the outer sheath. The inner sheath may be configured to engage an implantable electrode. In an example, the inner sheath may comprise a stimulation probe having an uninsulated portion at or near a distal end of the delivery sheath. The outer sheath may be coupled to a power source or stimulation signal generating circuitry at a proximal end. A clinician may control application of the stimulation signal to a tissue region via the outer sheath.
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公开(公告)号：US20230263588A1
公开(公告)日：2023-08-24
申请号：US18131550
申请日：2023-04-06
Applicant: SPR Therapeutics, Inc.
Inventor： Joseph W. Boggs , Amorn Wongsarnpigoon , Matthew G. deBock , Meredith J. McGee , Devin Sell , Robert B. Strother , Joey Groszek , Nathan D. Crosby , Matthew Wunzin , Brad Lewis , Bryce Dimit
CPC classification number: A61B90/11 , A61N1/0529
Abstract: An introducing device for locating a tissue region and deploying an electrode is shown and described. The introducing device may include an outer sheath. An inner sheath may be disposed within the outer sheath. The inner sheath may be configured to engage an implantable electrode. In an example, the inner sheath may comprise a stimulation probe having an uninsulated portion at or near a distal end of the delivery sheath. A sheath or needle may be coupled to a power source or stimulation signal generating circuitry at a proximal end. A clinician may control application of the stimulation signal to a tissue region via a sheath or needle.
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公开(公告)号：US20230148168A1
公开(公告)日：2023-05-11
申请号：US18079942
申请日：2022-12-13
Applicant: SPR Therapeutics, Inc.
Inventor： Joseph W. Boggs , Amorn Wongsarnpigoon , Matthew G. deBock , Nathan Crosby
IPC: A61N1/36
CPC classification number: A61N1/36021 , A61N1/36017 , A61N1/36071 , A61N1/0502 , A61N1/36034
Abstract: Device/system that provides pain relief by delivering stimulation that neither generates action potentials nor completely blocks neural transmission (in the peripheral nerve). The present teachings provide relief by modulating release of neurotransmitters in peripheral nerves to cause neuromodulation at the level of the peripheral nerve (modulation of neural signals in the peripheral nerve). The present teachings provide relief by modulating release of neurotransmitters in peripheral nerves to cause neuromodulation at the level of the peripheral nerve (modulation of neural signals in the peripheral nerve) to alter the frequency of physiologically generated neural transmission.
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公开(公告)号：US11420057B2
公开(公告)日：2022-08-23
申请号：US16587527
申请日：2019-09-30
Applicant: SPR Therapeutics, Inc.
Inventor： Joseph W. Boggs, II
Abstract: Systems and methods make possible the placement of one or more electrode leads in a tissue region for providing functional and/or therapeutic stimulation to tissue. The systems and methods are adapted to provide the relief of pain.
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