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公开(公告)号:US11458235B2
公开(公告)日:2022-10-04
申请号:US16466138
申请日:2017-12-05
Applicant: TEMASEK POLYTECHNIC , AWAK TECHNOLOGIES PTE LTD
Inventor: Christian Gert Bluchel , Peter Haywood
IPC: A61M1/16 , B01J39/17 , B01J20/02 , B01J20/24 , B01J47/02 , B01J47/04 , B01J20/20 , B01J39/12 , B01J41/10 , B01D15/08 , B01J47/024
Abstract: The invention relates to a sorbent for removing metabolic waste products from a dialysis liquid, the sorbent comprising a soluble source of sodium ions. The sorbent comprises an ion exchange system which converts urea to ammonium ions and which is configured to exchange ammonium ions for predominantly hydrogen ions and to exchange Ca, Mg, and K for predominantly sodium ions. The soluble source of sodium ions overcomes an initial drop in sodium concentration in regenerated dialysate. When used in conjunction with an infusion system configured to utilise exchange of Ca, Mg and K for sodium during dialysate regeneration a desired sodium ion concentration can be maintained.
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公开(公告)号:US20160151555A1
公开(公告)日:2016-06-02
申请号:US14982482
申请日:2015-12-29
Applicant: TEMASEK POLYTECHNIC
Inventor: Christian Gert BLUCHEL , Yanmei WANG , Kim Cheng TAN
CPC classification number: A61M1/3679 , A61M1/1696 , A61M1/28 , A61M1/3687 , B01D15/206 , B01D15/362 , B01D15/363 , B01J20/06 , B01J20/20 , B01J20/22 , B01J20/28052 , B01J39/12 , B01J41/10
Abstract: There is provided a sorbent for removing metabolic waste products from a dialysis liquid, the sorbent comprising a layer of immobilized uremic toxin-treating enzyme particles intermixed with cation exchange particles.
Abstract translation: 提供了用于从透析液中除去代谢废物的吸附剂,该吸附剂包含与阳离子交换颗粒混合的固定的尿毒症毒素处理酶颗粒层。
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公开(公告)号:US20150241613A1
公开(公告)日:2015-08-27
申请号:US14420833
申请日:2013-08-12
Inventor: Chee Fatt Chan , Beng Soon Tan , Yun Xu , Bee Khuan Jaslyn Law , Hong Yee Low
CPC classification number: G02B5/3058 , G02B5/1847 , G02B27/2214 , G02B27/225 , G02B27/26
Abstract: According to one aspect of the invention, there is provided an optical grating comprising a substrate comprising a plurality of protrusions with a space in between any two adjacent protrusions; and a cap provided on at least one of the plurality of protrusions at an end that is furthest from the substrate, wherein the cap has a higher degree of optical attenuation compared to the substrate material and wherein the combination of each protrusion and the respective cap thereon has a generally symmetric cross-sectional profile.
Abstract translation: 根据本发明的一个方面,提供了一种光栅,其包括:基板,包括多个突起,所述多个突起在任何两个相邻突起之间具有空间; 以及在距衬底最远的端部处设置在多个突起中的至少一个突起上的帽,其中与衬底材料相比,帽具有更高程度的光学衰减,并且其中每个突起和其上的相应帽的组合 具有大致对称的横截面轮廓。
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公开(公告)号:US20240058514A1
公开(公告)日:2024-02-22
申请号:US17918818
申请日:2021-04-13
Applicant: TEMASEK POLYTECHNIC
Inventor: Christian Gert BLUECHEL , Cathy Padua SAGUN , Puay Meng TANG , Liutong LIN, I , Hua ZHANG , Keng Hong LEE
IPC: A61M1/16 , A61M1/14 , A61M1/26 , B01D15/16 , B01D15/18 , B01D15/36 , B01J39/02 , B01J39/10 , B01J47/018 , B01J47/12
CPC classification number: A61M1/1696 , A61M1/1563 , A61M1/1605 , A61M1/267 , B01D15/166 , B01D15/18 , B01D15/362 , B01D15/363 , B01J39/02 , B01J39/10 , B01J47/018 , B01J47/12 , A61M2205/3331
Abstract: An aspect of the disclosure relates to a dialysate regenerator, including: a purification means; at least one reversible retainer including an ion reservoir; a dialysate flow path including a dialysate inlet for receiving a dialysate, a dialysate outlet for dispensing the dialysate, the purification means and the at least one reversible retainer: a pump connected to the dialysate flow path and configured to generate a flow of the dialysate from the dialysate inlet via the reversible retainer and the purification means to the dialysate outlet, wherein a direction of the dialysate flow path through the reversible retainer is reversible.
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公开(公告)号:US11600830B2
公开(公告)日:2023-03-07
申请号:US17005481
申请日:2020-08-28
Applicant: Temasek Polytechnic
Inventor: Ming Han , Yunzhong Chen , Lei Wang , Chun Yu Ling
IPC: H01M8/0254 , H01M8/0258 , H01M8/1004
Abstract: A plate member for a cell stack, a cell stack assembly, a method of forming a plate member for a cell stack and a method of assembling a cell stack may be provided, and the plate member includes a channel sheet with at least one peak and one trough for forming fluid flow channels; two alignment parts, each alignment part including a main body and one or more alignment members or holes, the main body having a through hole provided within the main body; and wherein the alignment part is capable of aligning the channel sheet parallel to a plane of the main body and the alignment member is capable of aligning the alignment member to another corresponding alignment member along an axis passing through the alignment member; and further wherein the channel sheet is disposed between the two alignment parts.
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公开(公告)号:US11590272B2
公开(公告)日:2023-02-28
申请号:US16792774
申请日:2020-02-17
Applicant: TEMASEK POLYTECHNIC
Inventor: Christian Gert Bluchel , Yanmei Wang , Kim Cheng Tan
IPC: A61M1/36 , A61M1/28 , B01J20/06 , B01J20/20 , B01J20/22 , B01J20/28 , B01J39/12 , B01J41/10 , A61M1/16 , B01D15/20 , B01D15/36
Abstract: There is provided a sorbent for removing metabolic waste products from a dialysis liquid, the sorbent comprising a layer of immobilized uremic toxin-treating enzyme particles intermixed with cation exchange particles.
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公开(公告)号:US11186482B2
公开(公告)日:2021-11-30
申请号:US16430142
申请日:2019-06-03
Applicant: TEMASEK POLYTECHNIC
Inventor: Lei Wang , Ming Han , Yunzhong Chen , Ee Ho Gareth Tang
Abstract: The present invention relates to a solid fuel, a system and a method for generating hydrogen. The solid fuel comprises sodium borohydride, catalyst loaded fibres and a binder, wherein the catalyst loaded fibres and the binder form a scaffold structure within which the sodium borohydride is positioned. The system comprises a fuel cartridge containing the solid fuel of the present invention for generating hydrogen gas, a reactor configured to house the fuel cartridge, a tank for storing water, a pump and a liquid conduit for conveying water from the tank to the fuel cartridge housed within the reactor to induce a hydrolysis reaction of the solid fuel contained in the fuel cartridge and a controller for regulating flow of the water.
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公开(公告)号:US20210205522A1
公开(公告)日:2021-07-08
申请号:US17209439
申请日:2021-03-23
Applicant: TEMASEK POLYTECHNIC
Inventor: Christian Gert Bluchel , Liutong Lin
Abstract: A dialysis device is provided including a disposable housing having a flow path along which dialysate received from a patient is subjected to contaminant removal when in operation. The device includes a controller for controlling the operation of the disposable housing and an interface capable of operably coupling the controller and the disposable housing to enable the contaminant removal from the dialysate. The flow path is fluidly sealed from the controller and interface.
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公开(公告)号:US10763518B2
公开(公告)日:2020-09-01
申请号:US15571845
申请日:2016-04-29
Applicant: TEMASEK POLYTECHNIC
Inventor: Ming Han , Yunzhong Chen , Lei Wang , Chun Yu Ling
IPC: H01M8/0254 , H01M8/0258 , H01M8/248 , H01M8/2483 , H01M8/2465 , H01M8/1018
Abstract: A plate member for a cell stack, a cell stack assembly, a method of forming a plate member for a cell stack and a method of assembling a cell stack may be provided, and the plate member comprises a channel sheet comprising at least one peak and one trough for forming fluid flow channels; two alignment parts, each alignment part comprising a main body and one or more alignment members, the main body having a through hole provided within the main body; and wherein the alignment part is capable of aligning the channel sheet parallel to a plane of the main body and the alignment member is capable of aligning the alignment member to another corresponding alignment member along an axis passing through the alignment member; and further wherein the channel sheet is disposed between the two alignment parts.
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公开(公告)号:US20190302022A1
公开(公告)日:2019-10-03
申请号:US16318946
申请日:2017-07-21
Applicant: Temasek Polytechnic , Agency for Science, Technology and Research , Tan Tock Seng Hospital Pte Ltd
Inventor: Ling Ling Sun , Willie Ng , Xiaodong Zhou , Ten It Wong , Yee Sin Leo
IPC: G01N21/552 , G01N21/01 , G01N33/74
Abstract: Disclosed is a localised surface plasmon resonance (LSPR) nanopillar assembly. The LSPR assembly is for use in sensing the presence of a biomarker when attached to a quantum dot. The LSPR assembly comprises a substrate and an array. The array comprises a LSPR nanopillar and a polymer spacer attached to the nanopillar. The LSPR assembly further comprises an antibody attached to the at least one polymer spacer. In the LSPR assembly, a combined height of the polymer spacer and antibody is selected by varying the number of monomer units of the polymer spacer, so that, when in use with the biomarker and the quantum dot, the quantum dot is at a predetermined distance from the nanopillar.
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