Abstract:
The invention provides methods and systems of determining biopolymer profiles and correlations between structural units (residues) of a biopolymer based on sampling of the conformational space available to the molecule. The correlations between these structural units can further be used to find networks within a biopolymer such as the coupled residue networks in a protein. The invention also provides for designing and engineering biopolymers including polypeptides, nucleic acids and carbohydrates using the information derived from the conformation clustering and subsequent methods described herein.
Abstract:
An LED bulb comprises a structural shell formed by folding a flat PCB into a three-dimensional polyhedron shape and a fitting for removably coupling the bulb to a light socket. The PCB comprises a plurality of LEDs, at least one LED mounted electronically on a plurality of faces of the polyhedron, and a driver circuit for driving each LED. The perimeter of the PCB is shaped to join adjacent faces. Each LED produces minimal excess heat, which is partially conducted by a metallic heat sink bridge to the PCB and dissipated to the air through the PCB and through a plurality of spaces in the shell.
Abstract:
The light intensity level of a dimmable LED bulb is set by interruption of the AC signal by the user. The bulb's driver circuit includes a controller having dimmer control logic for controlling the brightness. Optionally, the LED bulb can be dimmed by an external TRIAC dimmer.
Abstract:
A new density based clustering method for clustering data points in multidimensional space is described. Each point has a neighborhood consisting of all points that are within a preset cutoff radius or distance. Each point is assigned a density measure based on the number of points in its neighborhood. Any point that has a higher density than any of its neighboring points is the center of a cluster and is assigned a unique cluster ID. Every other point follows a path through the graph of neighboring points such that density is increasing as fast as possible until a cluster center is reached. The algorithm's performance is demonstrated on a one-dimensional, two-dimensional, and 18-dimensional dataset.
Abstract:
A new density based clustering method for clustering data points in multidimensional space is described. Each point has a neighborhood consisting of all points that are within a preset cutoff radius or distance. Each point is assigned a density measure based on the number of points in its neighborhood. Any point that has a higher density than any of its neighboring points is the centre of a cluster and is assigned a unique cluster ID. Every other point follows a path through the graph of neighboring points such that density is increasing as fast as possible until a cluster center is reached. The algorithm's performance is demonstrated on a one-dimensional, two-dimensional, and 18-dimensional dataset.
Abstract:
An LED bulb comprises a structural shell formed by folding a flat PCB into a three-dimensional polyhedron shape and a fitting for removably coupling the bulb to a light socket. The PCB comprises a plurality of LEDs, at least one LED mounted electronically on a plurality of faces of the polyhedron, and a driver circuit for driving each LED. The perimeter of the PCB is shaped to join adjacent faces. Each LED produces minimal excess heat, which is partially conducted by a metallic heat sink bridge to the PCB and dissipated to the air through the PCB and through a plurality of spaces in the shell.
Abstract:
The invention provides methods and systems of determining biopolymer profiles and correlations between structural units (residues) of a biopolymer based on sampling of the conformational space available to the molecule. The correlations between these structural units can further be used to find networks within a biopolymer such as the coupled residue networks in a protein. The invention also provides for designing and engineering biopolymers including polypeptides, nucleic acids and carbohydrates using the information derived from the conformation clustering and subsequent methods described herein.
Abstract:
The light intensity level of a dimmable LED bulb is set by interruption of the AC signal by the user. The bulb's driver circuit includes a controller having dimmer control logic for controlling the brightness. Optionally, the LED bulb can be dimmed by an external TRIAC dimmer.
Abstract:
An LED bulb comprises a structural shell formed by folding a flat PCB into a three-dimensional polyhedron shape and a fitting for removably coupling the bulb to a light socket. The PCB comprises a plurality of LEDs, at least one LED mounted electronically on a plurality of faces of the polyhedron, and a driver circuit for driving each LED. The perimeter of the PCB is shaped to join adjacent faces. Each LED produces minimal excess heat, which is partially conducted by a metallic heat sink bridge to the PCB and dissipated to the air through the PCB and through a plurality of spaces in the shell.