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公开(公告)号:US20190315844A1
公开(公告)日:2019-10-17
申请号:US16387282
申请日:2019-04-17
Applicant: ABBOTT LABORATORIES
Inventor: Bailin Tu , Robert N. Ziemann , Bryan C. Tieman , Philip M. Hemken , Carol S. Ramsay , Carolyn J. Strobel , David J. Hawksworth , Larry G. Birkenmeyer , Cheng Zhao , Susan E. Brophy , Barry L. Dowell , Anthony S. Muerhoff
IPC: C07K16/18 , G01N33/574 , G01N33/68
Abstract: Disclosed herein are antibodies and methods of using said antibodies to detect Golgi protein 73 (GP73) and fucosylated GP73 in a sample.
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公开(公告)号:US20140287532A1
公开(公告)日:2014-09-25
申请号:US14295116
申请日:2014-06-03
Applicant: Abbott Laboratories
Inventor: Toru Yoshimura , Kenju Fujita , Barry L. Dowell
IPC: G01N33/53
CPC classification number: G01N33/5306 , G01N33/57423 , G01N33/86 , G01N2333/5758
Abstract: To provide a more convenient and more accurate method of assaying ProGRP by improving the stability of ProGRP which is known to be unstable in a biological sample.By using a blood sample in a condition in which a blood coagulation factor is not activated is used as a sample, the degradation of ProGRP is suppressed, whereby it is possible to store a sample for a long period of time and to improve the accuracy of an assay.
Abstract translation: 通过提高已知在生物样品中不稳定的ProGRP的稳定性来提供更方便和更准确的测定ProGRP的方法。 通过使用血液凝固因子未活化的状态下的血液样品作为样品,可以抑制ProGRP的降解,能够长时间存储样品,提高准确度 一个测定。
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公开(公告)号:US10308709B2
公开(公告)日:2019-06-04
申请号:US15290762
申请日:2016-10-11
Applicant: ABBOTT LABORATORIES
Inventor: Bailin Tu , Robert N. Ziemann , Bryan C. Tieman , Philip M. Hemken , Carol S. Ramsay , Carolyn J. Strobel , David J. Hawksworth , Larry G. Birkenmeyer , Cheng Zhao , Susan E. Brophy , Barry L. Dowell , Anthony S. Muerhoff
IPC: G01N33/53 , C07K16/18 , G01N33/574 , G01N33/68
Abstract: Disclosed herein are antibodies and methods of using said antibodies to detect Golgi protein 73 (GP73) and fucosylated GP73 in a sample.
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4.Anti-GP73 monoclonal antibodies and methods of obtaining the same 有权
Title translation: 抗GP73单克隆抗体和获得相同的方法公开(公告)号:US09469686B2
公开(公告)日:2016-10-18
申请号:US13836229
申请日:2013-03-15
Applicant: Abbott Laboratories
Inventor: Bailin Tu , Robert N. Ziemann , Bryan C. Tieman , Philip M. Hemken , Carol S. Ramsay , Carolyn J. Strobel , David J. Hawksworth , Larry G. Birkenmeyer , Cheng Zhao , Susan E. Brophy , Barry L. Dowell , Anthony S. Muerhoff
IPC: C07K16/00 , A61K39/395 , C07K16/18 , G01N33/574 , G01N33/68
CPC classification number: C07K16/18 , C07K2317/21 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/92 , G01N33/57438 , G01N33/6893 , G01N2333/47 , G01N2800/085 , G01N2800/50
Abstract: Disclosed herein are antibodies and methods of using said antibodies to detect Golgi protein 73 (GP73) and fucosylated GP73 in a sample.
Abstract translation: 本文公开了使用所述抗体检测样品中的高尔基体蛋白73(GP73)和岩藻糖基化GP73的抗体和方法。
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公开(公告)号:US10942179B2
公开(公告)日:2021-03-09
申请号:US16057818
申请日:2018-08-08
Applicant: ABBOTT LABORATORIES
Inventor: Barry L. Dowell , Susan Gayda , Qiaoqiao Ruan , Joseph P. Skinner , Sergey Y. Tetin
IPC: G01N33/543 , G01N33/53
Abstract: Provided herein are assays and kits useful for avoiding “prozone phenomenon” or “hook effect” and which expand the range of accurately measurable analyte concentrations.
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公开(公告)号:US10073090B2
公开(公告)日:2018-09-11
申请号:US14842834
申请日:2015-09-02
Applicant: ABBOTT LABORATORIES
Inventor: Barry L. Dowell , Susan Gayda , Qiaoqiao Ruan , Joseph P. Skinner , Sergey Y. Tetin
IPC: G01N33/53 , G01N33/543
CPC classification number: G01N33/54393 , G01N33/5306 , G01N33/54306
Abstract: Provided herein are assays and kits useful for avoiding “prozone phenomenon” or “hook effect” and which expand the range of accurately measurable analyte concentrations.
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公开(公告)号:US10067124B2
公开(公告)日:2018-09-04
申请号:US15283828
申请日:2016-10-03
Applicant: Abbott Laboratories , Abbott Japan Co. Ltd.
Inventor: Toru Yoshimura , Kenju Fujita , Barry L. Dowell
IPC: G01N33/86 , G01N33/53 , G01N33/574
Abstract: To provide a more convenient and more accurate method of assaying ProGRP by improving the stability of ProGRP which is known to be unstable in a biological sample.By using a blood sample in a condition in which a blood coagulation factor is not activated is used as a sample, the degradation of ProGRP is suppressed, whereby it is possible to store a sample for a long period of time and to improve the accuracy of an assay.
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公开(公告)号:US09157910B2
公开(公告)日:2015-10-13
申请号:US13833655
申请日:2013-03-15
Applicant: ABBOTT LABORATORIES
Inventor: Barry L. Dowell , Susan Gayda , Qiaoqiao Ruan , Joseph P. Skinner , Sergey Y. Tetin
IPC: G01N33/53 , G01N33/543
CPC classification number: G01N33/54393 , G01N33/5306 , G01N33/54306
Abstract: Provided herein are assays and kits useful for avoiding “prozone phenomenon” or “hook effect” and which expand the range of accurately measurable analyte concentrations.
Abstract translation: 本文提供了可用于避免“前区现象”或“钩效应”的测定和试剂盒,并扩大了可精确测量的分析物浓度的范围。
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公开(公告)号:US11421023B2
公开(公告)日:2022-08-23
申请号:US16387282
申请日:2019-04-17
Applicant: ABBOTT LABORATORIES
Inventor: Bailin Tu , Robert N. Ziemann , Bryan C. Tieman , Philip M. Hemken , Carol S. Ramsay , Carolyn J. Strobel , David J. Hawksworth , Larry G. Birkenmeyer , Cheng Zhao , Susan E. Brophy , Barry L. Dowell , Anthony S. Muerhoff
IPC: G01N33/53 , C07K16/18 , G01N33/574 , G01N33/68
Abstract: Disclosed herein are antibodies and methods of using said antibodies to detect Golgi protein 73 (GP73) and fucosylated GP73 in a sample.
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公开(公告)号:US20170096477A1
公开(公告)日:2017-04-06
申请号:US15290762
申请日:2016-10-11
Applicant: ABBOTT LABORATORIES
Inventor: Bailin Tu , Robert N. Ziemann , Bryan C. Tieman , Philip M. Hemken , Carol S. Ramsay , Carolyn J. Strobel , David J. Hawksworth , Larry G. Birkenmeyer , Cheng Zhao , Susan E. Brophy , Barry L. Dowell , Anthony S. Muerhoff
CPC classification number: C07K16/18 , C07K2317/21 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/92 , G01N33/57438 , G01N33/6893 , G01N2333/47 , G01N2800/085 , G01N2800/50
Abstract: Disclosed herein are antibodies and methods of using said antibodies to detect Golgi protein 73 (GP73) and fucosylated GP73 in a sample.
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