公开(公告)号：US11975014B2

公开(公告)日：2024-05-07

申请号：US17228342

申请日：2021-04-12

Applicant: ABBOTT LABORATORIES

Inventor： Rachael Buck ,  Geralyn O. Duska-Mcewen ,  Joseph P. Schaller

IPC: A61K31/702 ,  A23L33/00 ,  A23L33/12 ,  A61K31/202 ,  A61K31/7016 ,  A61K45/06

CPC classification number: A61K31/702 ,  A23L33/12 ,  A23L33/40 ,  A61K31/202 ,  A61K31/7016 ,  A61K45/06 ,  A23V2002/00 ,  A23V2200/3202 ,  A23V2200/324 ,  A23V2250/1882 ,  A23V2250/28 ,  A61K2300/00 ,  A61K31/702 ,  A61K2300/00 ,  A61K31/7016 ,  A61K2300/00 ,  A61K31/202 ,  A61K2300/00 ,  A23V2002/00 ,  A23V2200/3202 ,  A23V2200/324 ,  A23V2250/1882 ,  A23V2250/28

Abstract: Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases.

公开(公告)号：US11464793B2

公开(公告)日：2022-10-11

申请号：US17099018

申请日：2020-11-16

Applicant: ABBOTT LABORATORIES

Inventor： Rachael Buck ,  Geralyn O. Duska-McEwen ,  Joseph P. Schaller

IPC: A61K31/702 ,  A23L33/00 ,  A23L33/12 ,  A61K31/202 ,  A61K31/7016 ,  A61K45/06

Abstract: Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases.

公开(公告)号：US10973837B2

公开(公告)日：2021-04-13

申请号：US16531849

申请日：2019-08-05

Applicant: ABBOTT LABORATORIES

Inventor： Rachael Buck ,  Geralyn O. Duska-McEwen ,  Joseph P. Schaller

IPC: A61K31/702 ,  A23L33/00 ,  A23L33/12 ,  A61K31/202 ,  A61K31/7016 ,  A61K45/06

Abstract: Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases.

公开(公告)号：US10471081B2

公开(公告)日：2019-11-12

申请号：US15401488

申请日：2017-01-09

Applicant: ABBOTT LABORATORIES

Inventor： JoMay Chow ,  Steven R. Davis ,  Rachael Buck ,  Geralyn O. Duska-McEwen ,  Hawley K. Linke

IPC: A01N43/04 ,  A61K31/715 ,  A61K31/702 ,  A61K31/716 ,  A61K45/06 ,  A23L33/00 ,  A23L33/10 ,  A23L33/12 ,  A23L33/19 ,  A23L33/135 ,  A61K9/107 ,  A61K31/733 ,  A61K35/20 ,  A61K35/744 ,  A61K35/745 ,  A61K35/747 ,  A61K36/48 ,  A61K38/01 ,  A61K35/00

Abstract: Disclosed are methods of reducing the incidence of necrotizing enterocolitis in an infant, toddler, or child using nutritional compositions including human milk oligosaccharides. The nutritional compositions including the human milk oligosaccharides are effective in reducing inflammation and the incidence of inflammatory diseases.

公开(公告)号：US10369164B2

公开(公告)日：2019-08-06

申请号：US15874604

申请日：2018-01-18

Applicant: ABBOTT LABORATORIES

Inventor： Rachael Buck ,  Geralyn O. Duska-McEwen ,  Joseph P. Schaller

IPC: A23L33/00 ,  A23L33/12 ,  A61K45/06 ,  A61K31/202 ,  A61K31/702 ,  A61K31/7016

Abstract: Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases.

公开(公告)号：US20150064220A1

公开(公告)日：2015-03-05

申请号：US14387871

申请日：2013-03-11

Applicant: ABBOTT LABORATORIES

Inventor： Debra L. Thomas ,  Rachael Buck

IPC: A61K31/702 ,  A23C9/20

CPC classification number: A61K31/702 ,  A23C9/206 ,  A23L33/10 ,  A23L33/40

Abstract: Disclosed are methods of enhancing cell-mediated immunity in an individual using nutritional compositions including human milk oligosaccharides. The human milk oligosaccharides are sialylated human milk oligosaccharides, fucosylated human milk oligosaccharides, or a combination of both. The human milk oligosaccharides may enhance T-cell mediated responses and T-cell regulatory responses.

Abstract translation: 公开的是使用包括人乳寡糖的营养组合在个体中增强细胞介导的免疫的方法。 人乳寡糖是唾液酸化的人乳低聚糖，岩藻糖化的人乳寡糖或两者的组合。 人乳寡糖可以增强T细胞介导的应答和T细胞调节反应。

公开(公告)号：US20240009217A1

公开(公告)日：2024-01-11

申请号：US18329047

申请日：2023-06-05

Applicant: ABBOTT LABORATORIES

Inventor： Rachael Buck ,  Debra Thomas ,  Joseph Schaller

IPC: A61K31/702 ,  A23L33/00 ,  A23L33/13 ,  A61K31/7068 ,  A61K31/7072 ,  A61K31/7076 ,  A61K31/708 ,  A61P1/12 ,  A23L33/125 ,  A61P31/12

CPC classification number: A61K31/702 ,  A23L33/40 ,  A23L33/13 ,  A61K31/7068 ,  A61K31/7072 ,  A61K31/7076 ,  A61K31/708 ,  A61P1/12 ,  A23L33/125 ,  A61P31/12 ,  A23V2200/32 ,  A23V2200/3202 ,  A23V2200/324 ,  A23V2250/284 ,  A23V2002/00 ,  A61K2300/00

Abstract: Disclosed are nutritional compositions including human milk oligosaccharides and nucleotides that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases.

公开(公告)号：US11207335B2

公开(公告)日：2021-12-28

申请号：US14456221

申请日：2014-08-11

Applicant: ABBOTT LABORATORIES

Inventor： Rachael Buck ,  Geralyn O. Duska-McEwen ,  Steven R. Davis

IPC: A01N43/04 ,  A61K31/70 ,  A61K31/702 ,  A23L33/00 ,  A61K31/716 ,  A23C9/20 ,  A61K31/05

Abstract: Disclosed are nutritional compositions including human milk oligosaccharides that can be administered to preterm infants, term infants, toddlers, and children for improving airway defense mechanisms.

公开(公告)号：US11197875B2

公开(公告)日：2021-12-14

申请号：US15893286

申请日：2018-02-09

Applicant: ABBOTT LABORATORIES

Inventor： Rachael Buck ,  Geralyn O. Duska-McEwen ,  Joseph P. Schaller

IPC: A01N43/04 ,  A61K31/70 ,  A61K31/702 ,  A23L33/00 ,  A23L33/12 ,  A61K31/202 ,  A61K31/7016 ,  A61K45/06

Abstract: Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases.

公开(公告)号：US10813940B2

公开(公告)日：2020-10-27

申请号：US15707477

申请日：2017-09-18

Applicant: ABBOTT LABORATORIES

Inventor： Rachael Buck ,  Debra Thomas ,  Joseph Schaller

IPC: A61K31/702 ,  A23L33/00 ,  A23L33/13 ,  A61K31/7068 ,  A61K31/7072 ,  A61K31/7076 ,  A61K31/708 ,  A61P1/12 ,  A23L33/125 ,  A61P31/12

Abstract: Disclosed are nutritional compositions including human milk oligosaccharides and nucleotides that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases.