公开(公告)号：US09675536B2

公开(公告)日：2017-06-13

申请号：US14895948

申请日：2014-06-05

Applicant: ADEKA CORPORATION

Inventor： Takao Sakamoto ,  Yasuhiro Tsushima

IPC: A61K8/42 ,  A61K8/86 ,  A61K8/34 ,  A61K8/04 ,  A61Q19/00 ,  A61K8/87

CPC classification number: A61K8/42 ,  A61K8/042 ,  A61K8/342 ,  A61K8/86 ,  A61K8/87 ,  A61K2800/10 ,  A61K2800/48 ,  A61K2800/592 ,  A61Q19/00

Abstract: The present invention relates to a gel-like composition for a cosmetic preparation including 0.05 part by mass to 3 parts by mass of a compound represented by the following general formula (1) with respect to 100 parts by mass of water, which is not destroyed by a change in pH or by the addition of a salt into the gel, and gives a feeling of use equivalent to that of a gel produced using an alkali thickening type gelling agent. where, R1 and R2 each represent an alkyl group having 28 to 36 carbon atoms, R3 and R4 each represent a hydrocarbon group having 4 to 13 carbon atoms, m and n each represent a number from 10 to 500, x represents a number from 1 to 1,000, and y represents a number from 0 to 10.

公开(公告)号：US09745407B2

公开(公告)日：2017-08-29

申请号：US14440432

申请日：2013-11-25

Applicant: ADEKA CORPORATION

Inventor： Takao Sakamoto ,  Yasuhiro Tsushima

IPC: C08G18/32 ,  C08G18/73 ,  A61K8/87 ,  C08G18/66 ,  C08G18/08 ,  C08G18/28 ,  A61Q19/00 ,  A61K8/06 ,  C08G18/48 ,  C08G18/76

CPC classification number: C08G18/73 ,  A61K8/062 ,  A61K8/87 ,  A61K2800/10 ,  A61K2800/48 ,  A61Q19/00 ,  C08G18/0866 ,  C08G18/283 ,  C08G18/2835 ,  C08G18/3206 ,  C08G18/4833 ,  C08G18/6674 ,  C08G18/7614

Abstract: A urethane polymer obtained by a reaction of: a monohydroxy compound (A), a polyethylene glycol (B), a monoglyceryl ether compound (C), and an isocyanate compound (D). This urethane polymer can be used as a urethane viscosity modifier excellent in long-term storage stability, similarly to alkali thickening-type viscosity modifiers, while having characteristics similar to those of existing urethane viscosity modifiers.

公开(公告)号：US11260003B2

公开(公告)日：2022-03-01

申请号：US16754002

申请日：2018-10-03

Applicant: ADEKA CORPORATION

Inventor： Yasuhiro Tsushima ,  Hiroshi Suzuki ,  Makiko Yazawa ,  Shotan Yamashita

IPC: A61K8/34 ,  A01N31/02

Abstract: An antimicrobial composition containing: a component (A) that is at least one selected from the group consisting of 1,2-alkanediols having an alkyl group having 6 to 8 carbons and monoalkyl glyceryl ethers having an alkyl group having 6 to 8 carbons; and a component (B) that is at least one selected from the group consisting of tripropylene glycol, 2-methyl-1,3-propanediol, and 3-methyl-1,3-butanediol and a cosmetic containing the antimicrobial composition.

公开(公告)号：US11771632B2

公开(公告)日：2023-10-03

申请号：US17669537

申请日：2022-02-11

Applicant: ADEKA CORPORATION

Inventor： Takao Sakamoto ,  Yasuhiro Tsushima ,  Yuki Takeishi

IPC: A61K8/86 ,  A61Q5/02 ,  A61K8/44 ,  A61K8/41 ,  A61K8/90 ,  A61Q19/10

CPC classification number: A61K8/44 ,  A61K8/416 ,  A61K8/90 ,  A61K2800/48 ,  A61K2800/596 ,  A61Q5/02 ,  A61Q19/10

Abstract: A skin- or hair-cleansing composition including a component (A), which is an aqueous gelling agent represented by general formula (1) described in the specification, and a component (B), which is an anionic surfactant, wherein the component (A) presents a viscosity of an aqueous solution containing 1 mass % of at 25° C. of 1,000 to 5,000 mPa·s and a clouding point of the aqueous solution containing 1 mass % of component (A) of 60° C. to 80° C., and has a weight average molecular weight of 10,000 to 30,000; a method for producing the aqueous gelling agent and a method for producing the skin- or hair-cleansing composition are provided.

公开(公告)号：US10729640B2

公开(公告)日：2020-08-04

申请号：US16327557

申请日：2017-08-28

Applicant: ADEKA CORPORATION

Inventor： Takao Sakamoto ,  Yasuhiro Tsushima ,  Yuki Takeishi

IPC: A61K8/87 ,  A61K8/04 ,  A61K8/34

Abstract: Provided is an aqueous gelling agent composition, including: compound (A) represented by the general formula (1); and compound (B) represented by the general formula (2), wherein a mass ratio of compound (A) to compound (B), (A): (B), is from 95:5 to 85:15: where R1, R2, R8, R9, R10, R11, R15, and R16 each independently represent a hydrocarbon group having 4 to 20 carbon atoms, R3, R5, R7, R12, and R14 each independently represent a divalent hydrocarbon group having 2 to 4 carbon atoms, R4, R6, and R13 each independently represent a divalent hydrocarbon group having 3 to 16 carbon atoms, a, e, j, and m each independently represent a number of 10 to 100, d represents a number of 100 to 500, and g represents a number of 1 to 10.

公开(公告)号：US10369096B2

公开(公告)日：2019-08-06

申请号：US15528780

申请日：2015-11-26

Applicant: ADEKA CORPORATION

Inventor： Takao Sakamoto ,  Yasuhiro Tsushima

IPC: C08K5/10 ,  A61K8/898 ,  A61K8/37 ,  A61K8/89 ,  C08G18/61 ,  C08G18/65 ,  C08L83/04 ,  C08L91/00 ,  A61K8/58 ,  A61Q19/00 ,  C08G18/24 ,  C08G18/28 ,  C08G18/32 ,  C08G18/73

Abstract: A polyurethane polyurea having strong thickening and gelling effects, obtained by reacting a polyurethane polyurea prepolymer obtained from a silicone derivative starting material having a specific structure, a specific diisocyanate compound starting material and a starting material made up of a compound represented by General Formula (C) (each of which is set forth in the Description), with either or both of a nitrogen compound having a specific structure and a hydroxyl group-containing compound having a specific structure (each of which is set forth in the Description.

公开(公告)号：US11918668B2

公开(公告)日：2024-03-05

申请号：US17277924

申请日：2019-09-20

Applicant: ADEKA CORPORATION

Inventor： Yasuhiro Tsushima ,  Hiroshi Suzuki ,  Kazuya Nakajima

IPC: A61K8/33 ,  A61K8/67

CPC classification number: A61K8/33 ,  A61K8/67 ,  A61K2800/10 ,  A61K2800/522 ,  A61K2800/805

Abstract: The present invention provides a method for producing a glyceryl ether-containing composition, the method including: a deodorization step for bringing a glyceryl ether-containing product selected from the group consisting of a monohexyl glyceryl ether-containing product, a monocyclohexyl glyceryl ether-containing product and a mixture thereof into contact with water vapor in an environment having a reduced pressure of 0.10 kPa or more and 10 kPa or less for 60 minutes or more and 600 minutes or less; and an addition step for adding 0.05 to 0.30 parts by mass of an antioxidant containing d-α-tocopherol to 100 parts by mass of the glyceryl ether-containing product, and also provides a glyceryl ether-containing composition containing specific amounts of a specific glyceryl ether and an antioxidant containing d-α-tocopherol.

公开(公告)号：US11464730B2

公开(公告)日：2022-10-11

申请号：US16644031

申请日：2018-08-28

Applicant: ADEKA CORPORATION

Inventor： Takao Sakamoto ,  Yasuhiro Tsushima ,  Yuki Takeishi

IPC: A61K8/88 ,  A61K8/36 ,  A61K8/73 ,  A61K8/81 ,  A61Q19/00

Abstract: A cosmetic composition including component (A), which is an aqueous gelling agent represented by general formula (1) described in the specification, and a component (B), which is a polymeric thickening agent, wherein the component (A) presents a viscosity of an aqueous solution containing 1 mass % of at 25° C. of 1,000 to 5,000 mPa·s and a clouding point of the aqueous solution containing 1 mass % of component (A) of 60° C. to 80° C., and has a weight average molecular weight of 10,000 to 30,000; a method for producing the aqueous gelling agent and a method for producing the cosmetic composition are provided.

公开(公告)号：US10137069B2

公开(公告)日：2018-11-27

申请号：US15119031

申请日：2014-12-16

Applicant: ADEKA CORPORATION

Inventor： Yasuhiro Tsushima ,  Hiroshi Suzuki

IPC: A61K8/34 ,  A61K8/44 ,  A61K8/49 ,  A61K8/55 ,  A61K8/60 ,  A61K8/365 ,  A61Q17/00 ,  A61Q19/00 ,  A61K8/33

Abstract: The present invention provides a skin cosmetic composition including a component (A) which is either one or both of hexyl glyceryl ether and cyclohexyl glyceryl ether, a component (B) which is either one or both of 1,2-propanediol and 1,3-propanediol, and a component (C) such as citric acid, an antibacterial agent including components (A), (B) and (C) and a method for enhancing an antibacterial effect of the component (A).

公开(公告)号：US20150299375A1

公开(公告)日：2015-10-22

申请号：US14440432

申请日：2013-11-25

Applicant: ADEKA CORPORATION

Inventor： Takao Sakamoto ,  Yasuhiro Tsushima

IPC: C08G18/73 ,  A61K8/87 ,  A61K8/06 ,  C08G18/28 ,  C08G18/32

CPC classification number: C08G18/73 ,  A61K8/062 ,  A61K8/87 ,  A61K2800/10 ,  A61K2800/48 ,  A61Q19/00 ,  C08G18/0866 ,  C08G18/283 ,  C08G18/2835 ,  C08G18/3206 ,  C08G18/4833 ,  C08G18/6674 ,  C08G18/7614

Abstract: The present invention is a urethane-type polymer obtained by a reaction of: a monohydroxy compound (A) represented by Formula (1), R1C2H4—OmH   (1) wherein R1 is an aliphatic hydrocarbon group having 24 to 36 carbon atoms, and m represents a number ranging from 0 to 1000; a polyethylene glycol (B) represented by Formula (2), HOC2H4—OnH   (2) wherein n represents a number ranging from 2 to 1000; a monoglyceryl ether compound (C) represented by Formula (3), wherein R2 represents an aliphatic hydrocarbon group having 5 to 12 carbon atoms; and an isocyanate compound (D) represented by Formula (4), R3NCO]q   (4) wherein R3 represents a hydrocarbon group having 4 to 13 carbon atoms, and q represents the number 2 or 3. This urethane-type polymer can be used as a urethane-type viscosity modifier excellent in long-term storage stability, similarly to alkali thickening-type viscosity modifiers, while having characteristics similar to those of existing urethane-type viscosity modifiers.

Abstract translation: 本发明是通过以下反应获得的氨基甲酸酯类聚合物：由式（1）表示的单羟基化合物（A），R 1为C 2 H 4 -O- O（1），其中R 1为具有24〜36个碳原子的脂族烃基 原子，m表示0〜1000的数; 由式（2）表示的聚乙二醇（B），HOc2H4-OnnH（2）其中n表示2至1000的数; 由式（3）表示的单甘油醚化合物（C），其中R2表示碳原子数为5〜12的脂肪族烃基; 和由式（4）表示的异氰酸酯化合物（D），R3aNCO] q（4）其中R3表示碳原子数4〜13的烃基，q表示2或3.这种氨基甲酸酯型聚合物 与碱增稠型粘度调节剂类似，可以用作长期保存稳定性优异的氨基甲酸酯型粘度调节剂，同时具有与现有氨基甲酸酯型粘度调节剂相似的特性。