公开(公告)号：US09539250B2

公开(公告)日：2017-01-10

申请号：US14612879

申请日：2015-02-03

Applicant: AbbVie Inc.

Inventor： Geoff G. Z. Zhang ,  Michael F. Bradley ,  David M. Barnes ,  Rodger Henry

IPC: A61K31/4709 ,  C07D401/14 ,  C07C31/26 ,  A61K47/02 ,  A61K47/12

CPC classification number: C07D401/14 ,  A61K31/4709 ,  A61K47/02 ,  A61K47/12 ,  C07C31/26

Abstract: A crystalline form of a drug, ways to make it, compositions containing it and methods of treatment of diseases and inhibition of adverse physiological events using it are disclosed.

Abstract translation: 公开了药物的结晶形式，其制备方法，含有它的组合物以及治疗疾病的方法以及使用其抑制不良生理事件。

公开(公告)号：US08969569B2

公开(公告)日：2015-03-03

申请号：US14175621

申请日：2014-02-07

Applicant: AbbVie Inc.

Inventor： Geoff G. Z. Zhang ,  Michael F. Bradley ,  David M. Barnes ,  Rodger Henry

IPC: C07D215/38 ,  A61K31/04 ,  C07D401/14 ,  C07C31/26

CPC classification number: C07D401/14 ,  A61K31/4709 ,  A61K47/02 ,  A61K47/12 ,  C07C31/26

Abstract: A crystalline form of a drug, ways to make it, compositions containing it and methods of treatment of diseases and inhibition of adverse physiological events using it are disclosed.

Abstract translation: 公开了药物的结晶形式，其制备方法，含有它的组合物以及治疗疾病的方法以及使用其抑制不良生理事件。

公开(公告)号：US10329276B2

公开(公告)日：2019-06-25

申请号：US15844904

申请日：2017-12-18

Applicant: AbbVie Inc.

Inventor： Geoff G. Z. Zhang ,  Michael F. Bradley ,  David M. Barnes ,  Rodger Henry

IPC: C07D401/14 ,  C07C31/26 ,  A61K31/4709 ,  A61K47/02 ,  A61K47/12

Abstract: A crystalline form of a drug, ways to make it, compositions containing it and methods of treatment of diseases and inhibition of adverse physiological events using it are disclosed.

公开(公告)号：US09873681B2

公开(公告)日：2018-01-23

申请号：US15359734

申请日：2016-11-23

Applicant: AbbVie Inc.

Inventor： Geoff G. Z. Zhang ,  Michael F. Bradley ,  David M. Barnes ,  Rodger Henry

IPC: C07D401/14 ,  C07C31/26 ,  A61K31/4709 ,  A61K47/02 ,  A61K47/12

CPC classification number: C07D401/14 ,  A61K31/4709 ,  A61K47/02 ,  A61K47/12 ,  C07C31/26

Abstract: A crystalline form of a drug, ways to make it, compositions containing it and methods of treatment of diseases and inhibition of adverse physiological events using it are disclosed.