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公开(公告)号：US20150018935A1
公开(公告)日：2015-01-15
申请号：US13937984
申请日：2013-07-09
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Stephen D. Pacetti , Richard Rapoza
IPC: A61F2/82
CPC classification number: A61F2/89 , A61F2/82 , A61F2/91 , A61F2/915 , A61F2002/9155 , A61F2230/0054 , Y10T29/49995
Abstract: An implantable stent includes a plurality of rings. At least a distal end ring has an eased corner feature formed in the polymer substrate at a radially outward, distal-facing corner of the ring while relatively sharp corners of the polymer substrate are maintained in radially inward corners of the ring.
Abstract translation: 可植入支架包括多个环。 至少一个远端环具有形成在聚合物基底中位于环的径向向外的远侧面角处的易折角特征，而聚合物基底的相对尖锐的角保持在环的径向向内的拐角处。
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公开(公告)号：US20140336747A1
公开(公告)日：2014-11-13
申请号：US14253760
申请日：2014-04-15
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Richard Rapoza , Nadine Ding , Yunbing Wang , Stephen Pacetti , Derek Mortisen
CPC classification number: A61F2/82 , A61L29/146 , A61L29/148 , A61L29/16 , A61L31/146 , A61L31/148 , A61L31/16 , A61L2300/414 , A61L2300/42
Abstract: Implants for treating insufficient blood flow to a heart muscle with transmyocardial revascularization are disclosed. Methods of treating insufficient blood flow to a heart muscle with the implant are also disclosed. The implant can have a body with an inner lumen that supports a channel in the heart muscle to allow for increased blood flow through the lumen upon implantation. The implant can include active agents to prevent or inhibit thrombotic closure of the channel, to promote vascularization, or both.
Abstract translation: 公开了用于治疗心肌血运重建的心肌不足的植入物。 还公开了用植入物治疗心肌不足的方法。 植入物可以具有内部内腔的主体，其支撑心肌中的通道，以允许在植入时通过内腔增加血流量。 植入物可以包括活性剂以预防或抑制通道的血栓闭塞，促进血管形成，或两者。
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公开(公告)号：US09987154B2
公开(公告)日：2018-06-05
申请号：US15154801
申请日：2016-05-13
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Stephen D. Pacetti , Richard Rapoza
CPC classification number: A61F2/89 , A61F2/82 , A61F2/91 , A61F2/915 , A61F2002/9155 , A61F2230/0054 , Y10T29/49995
Abstract: An implantable stent includes a plurality of rings. At least a distal end ring has an eased corner feature formed in the polymer substrate at a radially outward, distal-facing corner of the ring while relatively sharp corners of the polymer substrate are maintained in radially inward corners of the ring.
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公开(公告)号：US11135074B2
公开(公告)日：2021-10-05
申请号：US15785368
申请日：2017-10-16
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed Hossainy , Chad J. Abunassar , Michael Huy Ngo , Erik David Eli , Santosh V. Prabhu , Mikael Trollsas , Richard Rapoza
Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold has a structure that produces a low late lumen loss when implanted within a peripheral vessel and also exhibits a high axial fatigue life. In a preferred embodiment the scaffold forms ring structures interconnected by links, where a ring has 12 crowns and at most two links connecting adjacent rings.
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公开(公告)号：US10143572B2
公开(公告)日：2018-12-04
申请号：US14121435
申请日：2014-09-04
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Richard Rapoza , Susan Veldhof , James Oberhauser , Syed F. A. Hossainy
Abstract: A method of treating vascular disease in a patient is disclosed that comprises deploying a bioabsorbable polymer scaffold composed of a plurality of struts at a stenotic segment of an artery of a patient, wherein after the scaffold supports the segment at an increased diameter for a period of time the polymer degrades and is progressively replaced by de novo formation of malleable provisional matrix comprising proteoglycan, wherein as the scaffold becomes more malleable and becomes disconnected as it degrades, wherein following coverage of the struts by a neointima layer and loss of mechanical support provided by the scaffold, the scaffold is pulled outward by positive remodeling of the vessel wall of the scaffolded segment.
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Patent Agency Ranking
公开(公告)号：US09744058B2
公开(公告)日：2017-08-29
申请号：US13999356
申请日：2014-02-14
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Richard Rapoza
IPC: A61F2/82
CPC classification number: A61F2/82
Abstract: Treatments of coronary heart disease including the effect of endothelial shear stress (ESS) on neointimal formation following a bioresorbable vascular scaffold implantation are disclosed.
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7.发明申请公开(公告)号：US20170112646A1
公开(公告)日：2017-04-27
申请号：US15399632
申请日：2017-01-05
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Richard Rapoza , Yunbing Wang , James P. Oberhauser , Syed F.A. Hossainy
CPC classification number: A61F2/915 , A61F2/06 , A61F2/82 , A61F2/91 , A61F2/958 , A61F2002/825 , A61F2002/91566 , A61F2002/91583 , A61F2210/0004 , A61F2210/0076 , A61F2230/0054 , A61F2250/0067 , A61L31/06 , A61L31/148 , A61L31/16 , A61L2300/412 , C08L67/04
Abstract: Methods of treating a diseased blood vessel exhibiting stenosis with a bioabsorable stent are disclosed. The implanted stent supports the section of the vessel at an increased diameter for a period of time to allow the vessel to heal. The stent loses radial strength sufficient to support the section of the vessel in less than 6 months after implantation, loses mechanical integrity, and then erodes away from the section. The biodegradable stent results in changes in properties of plaque with time as the stent degrades. The time-dependent properties include the luminal area of the plaque and plaque geometric morphology parameters.
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公开(公告)号：US20160250047A1
公开(公告)日：2016-09-01
申请号：US15154801
申请日：2016-05-13
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Stephen D. Pacetti , Richard Rapoza
IPC: A61F2/91
CPC classification number: A61F2/89 , A61F2/82 , A61F2/91 , A61F2/915 , A61F2002/9155 , A61F2230/0054 , Y10T29/49995
Abstract: An implantable stent includes a plurality of rings. At least a distal end ring has an eased corner feature formed in the polymer substrate at a radially outward, distal-facing corner of the ring while relatively sharp corners of the polymer substrate are maintained in radially inward corners of the ring.
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公开(公告)号：US20150073536A1
公开(公告)日：2015-03-12
申请号：US14121435
申请日：2014-09-04
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Richard Rapoza , Susan Veldhof , James Oberhauser , Syed F.A. Hossainy
CPC classification number: A61F2/86 , A61F2/915 , A61F2002/91558 , A61F2002/91566 , A61F2210/0004 , A61F2250/0067 , A61L31/06 , A61L31/148 , A61L31/16 , A61L2300/422 , C08L67/04
Abstract: A method of treating vascular disease in a patient is disclosed that comprises deploying a bioabsorbable polymer scaffold composed of a plurality of struts at a stenotic segment of an artery of a patient, wherein after the scaffold supports the segment at an increased diameter for a period of time the polymer degrades and is progressively replaced by de novo formation of malleable provisional matrix comprising proteoglycan, wherein as the scaffold becomes more malleable and becomes disconnected as it degrades, wherein following coverage of the struts by a neointima layer and loss of mechanical support provided by the scaffold, the scaffold is pulled outward by positive remodeling of the vessel wall of the scaffolded segment.
Abstract translation: 公开了一种治疗患者血管疾病的方法，其包括在患者的动脉的狭窄部分部署由多个支柱构成的生物可吸收聚合物支架，其中在所述支架之后以增加的直径支撑所述片段一段时间 聚合物降解的时间逐渐被包含蛋白多糖的可延展的临时基质的从头形成所替代，其中当支架变得更有韧性并且随着其降解而变得断裂，其中由新内膜层覆盖支柱并且由 通过骨架段的血管壁的正重构，支架被向外拉。
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公开(公告)号：US10166129B2
公开(公告)日：2019-01-01
申请号：US14581993
申请日：2014-12-23
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Richard Rapoza , Yunbing Wang , James P. Oberhauser , Syed Hossainy
Abstract: Methods of treating a diseased blood vessel exhibiting stenosis with a bioabsorbable stent are disclosed. The implanted stent supports the section of the vessel at an increased diameter for a period of time to allow the vessel to heal. The stent loses radial strength sufficient to support the section of the vessel in less than 6 months after implantation, loses mechanical integrity, and then erodes away from the section. The biodegradable stent results in changes in properties of plaque with time as the stent degrades. The time-dependent properties include the luminal area of the plaque and plaque geometric morphology parameters.
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