公开(公告)号：US20140273061A1

公开(公告)日：2014-09-18

申请号：US14137392

申请日：2013-12-20

Applicant: Abbott Laboratories

Inventor： Jiong Wu ,  Ji Lin

IPC: G01N33/80

CPC classification number: G01N33/56972 ,  G01N15/0205 ,  G01N15/1434 ,  G01N15/1459 ,  G01N21/47 ,  G01N33/49 ,  G01N2015/0073 ,  G01N2015/0076 ,  G01N2015/0084 ,  G01N2015/0277 ,  G01N2015/1006 ,  G01N2015/1477 ,  G01N2015/1493

Abstract: Aspects of the invention include hematology analysis reagents, systems and methods that can be used to preserve blood cell morphology and integrity as well as provide sample integrity and optical clarity to facilitate optical analysis of blood samples. In some embodiments, the reagents include a non-phosphate organic buffer and a sphering surfactant. The pH and osmolality of the reagents may be adjusted to desired ranges. In addition, the reagents can be simply diluted with de-ionized water prior to use.

Abstract translation: 本发明的方面包括可用于保持血细胞形态和完整性的血液学分析试剂，系统和方法，以及提供样品完整性和光学透明度以促进血液样品的光学分析。 在一些实施方案中，试剂包括非磷酸盐有机缓冲剂和球形表面活性剂。 试剂的pH和重量克分子渗透浓度可以调节到所需的范围。 此外，试剂可以在使用前用去离子水简单稀释。

公开(公告)号：US11378578B2

公开(公告)日：2022-07-05

申请号：US14137392

申请日：2013-12-20

Applicant: Abbott Laboratories

Inventor： Jiong Wu ,  Ji Lin

IPC: G01N15/14 ,  G01N21/47 ,  G01N33/49 ,  G01N15/10 ,  G01N15/00 ,  G01N15/02 ,  G01N33/569

Abstract: Aspects of the invention include hematology analysis reagents, systems and methods that can be used to preserve blood cell morphology and integrity as well as provide sample integrity and optical clarity to facilitate optical analysis of blood samples. In some embodiments, the reagents include a non-phosphate organic buffer and a sphering surfactant. The pH and osmolality of the reagents may be adjusted to desired ranges. In addition, the reagents can be simply diluted with de-ionized water prior to use.