公开(公告)号：US10648905B2

公开(公告)日：2020-05-12

申请号：US15693151

申请日：2017-08-31

Applicant: Abbott Laboratories

Inventor： Patrick Fritchie ,  Michael Shawn Murphy ,  Michael Cobert

IPC: G01N21/00 ,  G01N33/00 ,  G01N21/25 ,  G06Q50/22 ,  G01N21/27 ,  G01N33/483 ,  G01N35/10

Abstract: Systems, apparatus, and related methods for evaluating biological sample integrity are disclosed herein. An example method includes scanning a sample container having a sample disposed therein to generate signal data including a first signal portion and a second signal portion. The example method includes detecting if the sample container includes a label attached to a surface of the sample container based on the second signal portion. If the sample container includes a label, the example method includes applying an adjustment factor to the second signal portion to create adjusted signal data. The example method includes determining a property of the sample based on one or more of the first signal portion or the adjusted signal data.

公开(公告)号：US20240279749A1

公开(公告)日：2024-08-22

申请号：US18557631

申请日：2022-04-29

Applicant: ABBOTT LABORATORIES

Inventor： Matthew Frankel ,  Patrick Fritchie ,  Gregg Williams ,  Bradley Weston

IPC: C12Q1/70 ,  B01L3/00 ,  C12Q1/6806 ,  C12Q1/6848 ,  G01N35/00 ,  G01N35/02 ,  G01N35/04 ,  G01N35/10

CPC classification number: C12Q1/70 ,  B01L3/502 ,  C12Q1/6806 ,  C12Q1/6848 ,  G01N35/0099 ,  G01N35/025 ,  B01L2200/0647 ,  B01L2200/141 ,  B01L2300/0829 ,  G01N2035/0406 ,  G01N2035/041 ,  G01N2035/0446 ,  G01N2035/103

Abstract: The presently disclosed subject matter relates to methods for rapid, sensitive, and high-throughput nucleic acid testing of biological samples, e.g., blood, serum, or plasma samples from donors, as well as systems capable of performing such high-throughput nucleic acid testing.

公开(公告)号：US11065352B2

公开(公告)日：2021-07-20

申请号：US15851199

申请日：2017-12-21

Applicant: Abbott Laboratories

Inventor： Patrick Fritchie ,  Pathik Soni ,  Lei Qiao ,  Dustin House ,  Lyle Yarnell ,  Edna Prieto-Ballengee ,  Cathy Forsythe ,  Michael Shawn Murphy ,  Andrew Fischer ,  Akanksha Sharma ,  Joseph Esposito ,  Matt Effinger ,  Michael Futer

IPC: A61L2/04 ,  H05B6/06 ,  H05B6/40 ,  A61L2/24 ,  H05B6/10 ,  H05B6/14

Abstract: Inductive heating systems and method of controlling the same to reduce biological carryover are disclosed herein. An example system includes an induction heater including a tank circuit. The example system includes a controller to drive the tank circuit to selectively oscillate at a resonant frequency for the tank circuit to inductively heat a work piece disposed proximate to the tank circuit.

公开(公告)号：US20180193498A1

公开(公告)日：2018-07-12

申请号：US15851199

申请日：2017-12-21

Applicant: Abbott Laboratories

Inventor： Patrick Fritchie ,  Pathik Soni ,  Lei Qiao ,  Dustin House ,  Lyle Yarnell ,  Edna Prieto-Ballengee ,  Cathy Forsythe ,  Michael Shawn Murphy ,  Andrew Fischer ,  Akanksha Sharma ,  Joseph Esposito ,  Matt Effinger ,  Michael Futer

IPC: A61L2/04 ,  H05B6/06 ,  H05B6/10 ,  H05B6/40 ,  A61L2/24

CPC classification number: A61L2/04 ,  A61L2/24 ,  A61L2202/14 ,  H05B6/06 ,  H05B6/101 ,  H05B6/108 ,  H05B6/14 ,  H05B6/40

Abstract: Inductive heating systems and method of controlling the same to reduce biological carryover are disclosed herein. An example system includes an induction heater including a tank circuit. The example system includes a controller to drive the tank circuit to selectively oscillate at a resonant frequency for the tank circuit to inductively heat a work piece disposed proximate to the tank circuit.

公开(公告)号：US20240210431A1

公开(公告)日：2024-06-27

申请号：US18557610

申请日：2022-04-29

Applicant: ABBOTT LABORATORIES

Inventor： Matthew Frankel ,  Patrick Fritchie ,  Gregg Williams ,  Bradley Weston

IPC: G01N35/02 ,  G01N35/04 ,  G01N35/10

CPC classification number: G01N35/025 ,  G01N35/1081 ,  G01N2035/0444

Abstract: Systems and methods for onboard pooling of samples for high-throughput analysis of the samples. Including a sample loading area for receiving a plurality of sample tubes, and a sample transport configured to continually transport individual vessels along a transport path from a sample dispense position to a sample capture and transfer position, with intermediate positions therebetween. At least one pipettor to transfer a first and second samples from the sample loading area to the sample transport and to pool the first sample and the second sample in a vessel on the sample transport to form a pooled sample. A sample transfer mechanism to capture at least a fractionated portion of the pooled sample from the vessel at the sample capture and transfer position and to transfer the at least a fractionated portion of the pooled sample for high-throughput analysis.

公开(公告)号：US20210338856A1

公开(公告)日：2021-11-04

申请号：US17375737

申请日：2021-07-14

Applicant: Abbott Laboratories

Inventor： Patrick Fritchie ,  Pathik Soni ,  Lei Qiao ,  Dustin House ,  Lyle Yarnell ,  Edna Prieto-Ballengee ,  Cathy Forsythe ,  Michael Shawn Murphy ,  Andrew Fischer ,  Akanksha Sharma ,  Joseph Esposito ,  Matt Effinger ,  Michael Futer

IPC: A61L2/04 ,  H05B6/10 ,  H05B6/14 ,  A61L2/24 ,  H05B6/06 ,  H05B6/40

Abstract: Inductive heating systems and method of controlling the same to reduce biological carryover are disclosed herein. An example system includes an induction heater including a tank circuit, the tank circuit including a work coil and a sense coil. The sense coil is to detect a magnetic field generated by the work coil and to output signals in response to the detection. The example system includes a controller to cause the tank circuit to oscillate at a resonant frequency in response to the signals and a power drive unit in communication with the controller and the induction heater. The power drive unit is to adjust power provided to the induction heater in response to the controller driving the tank circuit to oscillate at the resonant frequency.

公开(公告)号：US20180059006A1

公开(公告)日：2018-03-01

申请号：US15693151

申请日：2017-08-31

Applicant: Abbott Laboratories

Inventor： Patrick Fritchie ,  Michael Shawn Murphy ,  Michael Cobert

IPC: G01N21/25 ,  G01N21/27 ,  G01N33/483

CPC classification number: G01N21/255 ,  G01N21/00 ,  G01N21/27 ,  G01N33/483 ,  G01N35/1011 ,  G01N2201/10 ,  G01N2201/12 ,  G06Q50/22

Abstract: Systems, apparatus, and related methods for evaluating biological sample integrity are disclosed herein. An example method includes scanning a sample container having a sample disposed therein to generate signal data including a first signal portion and a second signal portion. The example method includes detecting if the sample container includes a label attached to a surface of the sample container based on the second signal portion. If the sample container includes a label, the example method includes applying an adjustment factor to the second signal portion to create adjusted signal data. The example method includes determining a property of the sample based on one or more of the first signal portion or the adjusted signal data.