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    Systems, apparatus, and related methods for evaluating biological sample integrity
    2.
    发明授权
    Systems, apparatus, and related methods for evaluating biological sample integrity 有权

    公开(公告)号：US11187650B2

    公开(公告)日：2021-11-30

    申请号：US16805029

    申请日：2020-02-28

    Applicant: Abbott Laboratories

    Inventor： Patrick P. Fritchie ,  Michael Shawn Murphy ,  Michael Cobert

    IPC: G01N21/25 ,  G01N21/00 ,  G01N21/27 ,  G01N33/483 ,  G06Q50/22 ,  G01N35/10

    Abstract: Systems, apparatus, and related methods for evaluating biological sample integrity are disclosed herein. An example method includes scanning a sample container having a sample disposed therein to generate signal data including a first signal portion and a second signal portion. The example method includes detecting if the sample container includes a label attached to a surface of the sample container based on the second signal portion. If the sample container includes a label, the example method includes applying an adjustment factor to the second signal portion to create adjusted signal data. The example method includes determining a property of the sample based on one or more of the first signal portion or the adjusted signal data.

    Systems and methods for managing inventories of reagents
    5.
    发明授权
    Systems and methods for managing inventories of reagents 有权
    用于管理试剂库存的系统和方法

    公开(公告)号：US09261523B2

    公开(公告)日：2016-02-16

    申请号：US14152779

    申请日：2014-01-10

    Applicant: Abbott Laboratories

    Inventor： Patrick P. Fritchie ,  John C. Jones ,  Oscar F. Schwartz

    IPC: G01N35/00 ,  G06Q10/08 ,  G06Q10/00

    CPC classification number: G01N35/00663 ,  G01N35/00584 ,  G01N35/00732 ,  G01N35/0099 ,  G01N35/04 ,  G01N2035/00435 ,  G01N2035/00673 ,  G01N2035/00762 ,  G01N2035/00811 ,  G01N2035/00821 ,  G01N2035/0091 ,  G06Q10/087 ,  Y10T436/11 ,  Y10T436/13

    Abstract: A system for managing the inventory of reagents for a laboratory automation system. The system for managing the inventory of reagents comprises a controller, software for the controller, and a refrigerator capable of refrigerating reagents, detecting the presence or absence of reagents in the refrigerator, and detecting the location of reagents in the refrigerator. The system for managing the inventory of reagents is connected to a laboratory automation system. The laboratory automation system comprises at least one clinical analyzer. A typical system for managing inventories of reagents includes an operator interface for the loading of boxes of reagents and other supplies, radio frequency identification system for identification of inventory and tracking, robotic mechanisms for loading containers onto the track system and removing containers from the track system, de-capping equipment, refrigeration equipment, and information technology connections to laboratory analyzers and vendors.

    Abstract translation: 用于管理实验室自动化系统试剂库存的系统。 用于管理试剂库存的系统包括控制器，用于控制器的软件和能够冷藏试剂的冰箱，检测冰箱中试剂的存在或不存在以及检测冰箱中试剂的位置。 用于管理试剂库存的系统连接到实验室自动化系统。 实验室自动化系统至少包括一个临床分析仪。 用于管理试剂库存的典型系统包括用于装载试剂盒和其他用品的操作者界面，用于识别库存和跟踪的射频识别系统，用于将容器装载到轨道系统上的机器人机构以及从轨道系统中移出容器 ，脱帽设备，制冷设备以及与实验室分析仪和供应商的信息技术连接。

    System for managing inventory of bulk liquids
    6.
    发明授权
    System for managing inventory of bulk liquids 有权
    管理散装液体库存的系统

    公开(公告)号：US08951805B2

    公开(公告)日：2015-02-10

    申请号：US14247887

    申请日：2014-04-08

    Applicant: Abbott Laboratories

    Inventor： Patrick P. Fritchie ,  Gregory E. Gardner ,  Richard W. Mahoney

    IPC: G01N15/06 ,  G01N33/00 ,  G01N33/48 ,  G01N1/28 ,  G01N35/10

    CPC classification number: G01N35/1002 ,  G01N1/28 ,  G01N35/1009 ,  G01N35/1016 ,  G01N35/1065 ,  G01N35/1074 ,  G01N2035/1025 ,  Y10T436/11 ,  Y10T436/25 ,  Y10T436/25625 ,  Y10T436/2575

    Abstract: A system for managing bulk liquids for an automated clinical analyzer. The system comprises (a) at least one local reservoir for storing a bulk liquid for impending use, (b) at least one container for holding a bulk liquid before the liquid is transferred to a local reservoir, and (c) a controller for monitoring the level of a bulk liquid in a local reservoir. The local reservoir for storing a bulk liquid for impending use can be a trough. The use of troughs for storing a reagent, a diluent, or some other treating agent for impending use enables an aspirating/dispensing device having a plurality of pipettes to aspirate and dispense the reagent, diluent, or other treating agent at a high rate of throughput. The controller can monitor the level of a liquid in (a) a local reservoir for storing a bulk liquid for imminent use and the level of liquid in a (b) container for holding a bulk liquid before the liquid is transferred to a local reservoir. In the laboratory automation system described herein, the container for holding a bulk liquid before the liquid is transferred to a local reservoir can be a bottle. Other desirable features in the system include, but are not limited to, pump(s), valves, liquid level sensors.

    Abstract translation: 用于管理自动化临床分析仪的散装液体的系统。 该系统包括（a）至少一个用于储存即将使用的散装液体的局部储存器，（b）至少一个用于在液体被转移到局部储存器之前保持散装液体的容器，以及（c）用于监测的控制器 局部水库中大量液体的水平。 用于储存即将使用的散装液体的局部储存罐可以是槽。 用于储存用于即将使用的试剂，稀释剂或一些其它处理剂的槽使得具有多个移液管的抽吸/分配装置可以以高生产率将吸入和分配试剂，稀释剂或其它处理剂 。 控制器可以监测（a）用于储存即将使用的散装液体的局部储存器中的液体的液面，以及（b）容器中用于保存大量液体的液体的液面，然后液体被转移到局部储存器。 在本文所述的实验室自动化系统中，在将液体转移到局部储存器之前用于保持散装液体的容器可以是瓶子。 该系统中的其它期望特征包括但不限于泵，阀，液位传感器。

    SYSTEM APPARATUS, AND METHOD FOR CLOSED TUBE SAMPLING AND OPEN TUBE SAMPLING FOR AUTOMATIC CLINICAL ANALYZERS
    8.
    发明申请
    SYSTEM APPARATUS, AND METHOD FOR CLOSED TUBE SAMPLING AND OPEN TUBE SAMPLING FOR AUTOMATIC CLINICAL ANALYZERS 审中-公开
    用于自动临床分析仪的封闭管采样和开放管采样的系统设备及方法

    公开(公告)号：US20150251193A1

    公开(公告)日：2015-09-10

    申请号：US14720053

    申请日：2015-05-22

    Applicant: Abbott Laboratories

    Inventor： Patrick P. Fritchie

    IPC: B04B5/04 ,  B01D21/26 ,  B04B7/12

    CPC classification number: B04B5/0421 ,  B01D21/262 ,  B04B7/12 ,  B04B9/146 ,  B04B11/04 ,  B04B2011/046 ,  G01N2035/00504

    Abstract: A centrifuge to which sample tubes can be introduced while the centrifuge is in motion. The centrifuge comprises a carousel having an upper portion and a lower portion. The upper portion of the carousel has a plurality of positions for sample tubes for a centrifugation operation, a plurality of drive mechanisms attached to the upper portion of the carousel, a movable element mounted upon each drive mechanism, the movable element capable of traversing the length of the drive mechanism when the drive mechanism is actuated, a sample tube-holding assembly comprising a sample tube holder and a bearing attached to each movable element, and at least one balancing element capable of contributing to a force vector that cancels an imbalance vector generated by rotation of the centrifuge.

    Abstract translation: 在离心机运动时可以将样品管引入的离心机。 离心机包括具有上部和下部的转盘。 转盘的上部具有用于离心操作的样品管的多个位置，附接到转盘的上部的多个驱动机构，安装在每个驱动机构上的可移动元件，可移动元件能够横过长度 驱动机构被致动时的一个样品管保持组件，其包括样品管保持器和附接到每个可移动元件的轴承，以及至少一个平衡元件，其能够有助于抵抗产生的不平衡矢量的力矢量 通过旋转离心机。

    System and Method for Processing Both Clinical Chemistry and Immunoassay Tests
    9.
    发明申请
    System and Method for Processing Both Clinical Chemistry and Immunoassay Tests 审中-公开
    用于临床化学和免疫测定测试的系统和方法

    公开(公告)号：US20140271369A1

    公开(公告)日：2014-09-18

    申请号：US14214210

    申请日：2014-03-14

    Applicant: ABBOTT LABORATORIES

    Inventor： Patrick P. Fritchie

    IPC: G01N35/00

    CPC classification number: G01N35/025 ,  G01N21/6428 ,  G01N35/0098 ,  G01N2021/6441 ,  G01N2035/00356 ,  G01N2035/0453 ,  G01N2035/1032

    Abstract: Disclosed herein are instruments, systems and methods for performing automated integrated analysis of both clinical chemistry assay and immunoassay tests on a sample. The system includes a common process subsystem module; a clinical chemistry analyzer module; an immunoassay analyzer module; and a plurality of additional modules. The common process subsystem module is configured to position one or more reaction vessels containing aliquots of the sample for analysis by the clinical chemistry analyzer module, the immunochemistry analyzer module or both analyzer modules. The included immunochemistry analyzer module of the instrument and system is configured to perform multiplex FRET analysis on homogeneous solutions, thereby increasing the flexibility, throughput and robustness of the resultant instrument and systems.

    Abstract translation: 本文公开了用于对样品进行临床化学测定和免疫测定测试的自动化综合分析的仪器，系统和方法。 该系统包括一个通用的进程子系统模块; 临床化学分析仪模块; 免疫分析仪模块; 和多个附加模块。 常用的工艺子系统模块被配置成定位一个或多个反应容器，其中含有样品的等分试样用于临床化学分析器模块，免疫化学分析器模块或两个分析器模块的分析。 仪器和系统的免疫化学分析仪模块被配置为对均匀解决方案进行多路FRET分析，从而增加了所得仪器和系统的灵活性，吞吐量和鲁棒性。

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