公开(公告)号：US11085064B2

公开(公告)日：2021-08-10

申请号：US16805390

申请日：2020-02-28

Applicant: Accelerate Diagnostics, Inc.

Inventor： Austin Ashby ,  Wayne Showalter ,  Jasmin Cote

IPC: C12Q1/02 ,  G02B7/28 ,  G01N15/06 ,  G01N21/64 ,  B01L3/00 ,  C12Q1/04 ,  G01N1/38 ,  G01N35/02 ,  G01N35/10 ,  G01N35/04 ,  G01N35/00

Abstract: A system for automated microorganism identification and antibiotic susceptibility testing comprising a reagent cartridge, a reagent stage, a cassette, a cassette, stage, a pipettor assembly, an optical detection system, and a controller is disclosed. The system is designed to dynamically adjust motor idle torque to control heat load and employs a fast focus process for determining the true focus position of an individual microorganism. The system also may quantify the relative abundance of viable microorganisms in a sample using dynamic dilution, and facilitate growth of microorganisms in customized media for rapid, accurate antimicrobial susceptibility testing.

公开(公告)号：US20180135093A1

公开(公告)日：2018-05-17

申请号：US15849297

申请日：2017-12-20

Applicant: Accelerate Diagnostics, Inc.

Inventor： Austin Ashby ,  Wayne Showalter ,  Jasmin Cote

IPC: C12Q1/02 ,  G02B7/28 ,  C12Q1/04 ,  G01N1/38 ,  G01N15/06 ,  B01L3/00 ,  G01N35/02 ,  G01N35/10 ,  H04N5/232 ,  G01N21/64 ,  G01N35/00 ,  G01N35/04

CPC classification number: C12Q1/025 ,  B01L3/527 ,  B01L2300/0893 ,  C12Q1/04 ,  G01N1/38 ,  G01N15/06 ,  G01N21/6458 ,  G01N35/025 ,  G01N35/1002 ,  G01N2015/0693 ,  G01N2021/6419 ,  G01N2035/00346 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0446 ,  G01N2035/0455 ,  G01N2035/1032 ,  G02B7/28 ,  H04N5/23212

Abstract: A system for automated microorganism identification and antibiotic susceptibility testing comprising a reagent cartridge, a reagent stage, a cassette, a cassette, stage, a pipettor assembly, an optical detection system, and a controller is disclosed. The system is designed to dynamically adjust motor idle torque to control heat load and employs a fast focus process for determining the true focus position of an individual microorganism. The system also may quantify the relative abundance of viable microorganisms in a sample using dynamic dilution, and facilitate growth of microorganisms in customized media for rapid, accurate antimicrobial susceptibility testing.

公开(公告)号：US20190203252A1

公开(公告)日：2019-07-04

申请号：US16297356

申请日：2019-03-08

Applicant: Accelerate Diagnostics, Inc.

Inventor： Austin Ashby ,  Wayne Showalter ,  Jasmin Cote

IPC: C12Q1/02 ,  G01N21/64 ,  G01N35/10 ,  G01N35/02 ,  H04N5/232 ,  C12Q1/04 ,  G01N1/38 ,  G02B7/28 ,  G01N15/06 ,  B01L3/00

CPC classification number: C12Q1/025 ,  B01L3/527 ,  B01L2300/0893 ,  C12Q1/04 ,  G01N1/38 ,  G01N15/06 ,  G01N21/6458 ,  G01N35/025 ,  G01N35/1002 ,  G01N2015/0693 ,  G01N2021/6419 ,  G01N2035/00346 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0446 ,  G01N2035/0455 ,  G01N2035/1032 ,  G02B7/28 ,  H04N5/23212

Abstract: A system for automated microorganism identification and antibiotic susceptibility testing comprising a reagent cartridge, a reagent stage, a cassette, a cassette, stage, a pipettor assembly, an optical detection system, and a controller is disclosed. The system is designed to dynamically adjust motor idle torque to control heat load and employs a fast focus process for determining the true focus position of an individual microorganism. The system also may quantify the relative abundance of viable microorganisms in a sample using dynamic dilution, and facilitate growth of microorganisms in customized media for rapid, accurate antimicrobial susceptibility testing.

公开(公告)号：US20210008541A1

公开(公告)日：2021-01-14

申请号：US16908516

申请日：2020-06-22

Applicant: Accelerate Diagnostics, Inc.

Inventor： Kevin Marshall ,  Austin Ashby ,  Josh Harrison ,  Steven W. Metzger ,  Wayne Showalter ,  Erik Molina ,  Jamie Roberson

IPC: B01L3/02

Abstract: Systems and methods for automated biological sample preparation for use in rapid identification and antimicrobial susceptibility testing of microorganisms, such as bacteria and fungi, are provided.

公开(公告)号：US10669566B2

公开(公告)日：2020-06-02

申请号：US16007071

申请日：2018-06-13

Applicant: Accelerate Diagnostics, Inc.

Inventor： William L. Richards ,  Austin Ashby ,  Matthew Ketterer ,  Kevin Marshall ,  Josh Harrison ,  Matthew Mette ,  Paul Richards ,  Wayne Showalter ,  Jasmin Cote ,  Steven W. Metzger ,  Ken Hance ,  Meghan Mensack ,  Carlos Michel ,  Elke Allers ,  Dulini Gamage ,  Landon Prisbrey ,  Oleg Gusyatin ,  Alena Shamsheyeva ,  Ben Turng ,  Andrew Ghusson ,  Kurt Reinhardt ,  Phillip C. Halbert ,  Solene Bourgeois

IPC: C12Q1/02 ,  G02B7/28 ,  G01N15/06 ,  G01N21/64 ,  B01L3/00 ,  C12Q1/04 ,  G01N1/38 ,  G01N35/02 ,  G01N35/10 ,  H04N5/232 ,  G01N35/04 ,  G01N35/00

Abstract: A system for automated microorganism identification and antibiotic susceptibility testing comprising a reagent cartridge, a reagent stage, a cassette, a cassette, stage, a pipettor assembly, an optical detection system, and a controller is disclosed. The system is designed to dynamically adjust motor idle torque to control heat load and employs a fast focus process for determining the true focus position of an individual microorganism. The system also may quantify the relative abundance of viable microorganisms in a sample using dynamic dilution, and facilitate growth of microorganisms in customized media for rapid, accurate antimicrobial susceptibility testing.

公开(公告)号：US10253355B2

公开(公告)日：2019-04-09

申请号：US15283922

申请日：2016-10-03

Applicant: Accelerate Diagnostics, Inc.

Inventor： William L. Richards ,  Austin Ashby ,  Matthew Ketterer ,  Kevin Marshall ,  Josh Harrison ,  Matthew Mette ,  Paul Richards ,  Wayne Showalter ,  Jasmin Cote ,  Phillip C. Halbert ,  Solene Bourgeois ,  Steven W. Metzger ,  Ken Hance ,  Meghan Mensack ,  Carlos Michel ,  Elke Allers ,  Dulini Gamage ,  Landon Prisbrey ,  Oleg Gusyatin ,  Alena Shamsheyeva ,  Ben Turng ,  Andrew Ghusson ,  Kurt Reinhardt

IPC: C12Q1/6841 ,  C12Q1/02 ,  G02B7/28 ,  G01N21/64 ,  G01N35/02 ,  H04N5/232 ,  G01N35/00 ,  C12M1/34 ,  G01N35/10 ,  B01L3/00

Abstract: A system for automated microorganism identification and antibiotic susceptibility testing comprising a reagent cartridge, a reagent stage, a cassette, a cassette, stage, a pipettor assembly, an optical detection system, and a controller is disclosed. The system is designed to dynamically adjust motor idle torque to control heat load and employs a fast focus process for determining the true focus position of an individual microorganism. The system also may quantify the relative abundance of viable microorganisms in a sample using dynamic dilution, and facilitate growth of microorganisms in customized media for rapid, accurate antimicrobial susceptibility testing. Automated quality control test components and methods of their use are also disclosed.

公开(公告)号：US20220162664A1

公开(公告)日：2022-05-26

申请号：US17364755

申请日：2021-06-30

Applicant: Accelerate Diagnostics, Inc.

Inventor： Austin Ashby ,  Wayne Showalter ,  Jasmin Cote

IPC: C12Q1/02 ,  G02B7/28 ,  G01N15/06 ,  G01N21/64 ,  B01L3/00 ,  C12Q1/04 ,  G01N1/38 ,  G01N35/02 ,  G01N35/10

Abstract: A system for automated microorganism identification and antibiotic susceptibility testing comprising a reagent cartridge, a reagent stage, a cassette, a cassette, stage, a pipettor assembly, an optical detection system, and a controller is disclosed. The system is designed to dynamically adjust motor idle torque to control heat load and employs a fast focus process for determining the true focus position of an individual microorganism. The system also may quantify the relative abundance of viable microorganisms in a sample using dynamic dilution, and facilitate growth of microorganisms in customized media for rapid, accurate antimicrobial susceptibility testing.

公开(公告)号：US20180291419A1

公开(公告)日：2018-10-11

申请号：US16007071

申请日：2018-06-13

Applicant: Accelerate Diagnostics, Inc.

Inventor： William L. Richards ,  Austin Ashby ,  Matthew Ketterer ,  Kevin Marshall ,  Josh Harrison ,  Matthew Mette ,  Paul Richards ,  Wayne Showalter ,  Jasmin Cote ,  Steven W. Metzger ,  Ken Hance ,  Meghan Mensack ,  Carlos Michel ,  Elke Allers ,  Dulini Gamage ,  Landon Prisbrey ,  Oleg Gusyatin ,  Alena Shamsheyeva ,  Ben Turng ,  Andrew Ghusson ,  Kurt Reinhardt ,  Phillip C. Halbert ,  Solene Bourgeois

IPC: C12Q1/02 ,  G02B7/28 ,  C12Q1/04 ,  G01N1/38 ,  G01N15/06 ,  B01L3/00 ,  G01N35/02 ,  G01N35/10 ,  H04N5/232 ,  G01N21/64 ,  G01N35/00 ,  G01N35/04

Abstract: A system for automated microorganism identification and antibiotic susceptibility testing comprising a reagent cartridge, a reagent stage, a cassette, a cassette, stage, a pipettor assembly, an optical detection system, and a controller is disclosed. The system is designed to dynamically adjust motor idle torque to control heat load and employs a fast focus process for determining the true focus position of an individual microorganism. The system also may quantify the relative abundance of viable microorganisms in a sample using dynamic dilution, and facilitate growth of microorganisms in customized media for rapid, accurate antimicrobial susceptibility testing.

公开(公告)号：US10023895B2

公开(公告)日：2018-07-17

申请号：US15085953

申请日：2016-03-30

Applicant: Accelerate Diagnostics, Inc.

Inventor： William L. Richards ,  Austin Ashby ,  Matthew Ketterer ,  Kevin Marshall ,  Josh Harrison ,  Matthew Mette ,  Paul Richards ,  Wayne Showalter ,  Jasmin Cote ,  Phillip C. Halbert ,  Solene Bourgeois ,  Steven W. Metzger ,  Ken Hance ,  Meghan Mensack ,  Carlos Michel ,  Elke Allers ,  Dulini Gamage ,  Landon Prisbrey ,  Oleg Gusyatin ,  Alena Shamsheyeva ,  Ben Turng ,  Andrew Ghusson ,  Kurt Reinhardt

IPC: C12Q1/18 ,  C12Q1/02 ,  B01L3/00 ,  C12Q1/04 ,  G01N1/38 ,  G01N35/02 ,  G01N35/10 ,  H04N5/232 ,  G02B7/28 ,  G01N15/06 ,  G01N21/64 ,  G01N35/04 ,  G01N35/00

Abstract: A system for automated microorganism identification and antibiotic susceptibility testing comprising a reagent cartridge, a reagent stage, a cassette, a cassette, stage, a pipettor assembly, an optical detection system, and a controller is disclosed. The system is designed to dynamically adjust motor idle torque to control heat load and employs a fast focus process for determining the true focus position of an individual microorganism. The system also may quantify the relative abundance of viable microorganisms in a sample using dynamic dilution, and facilitate growth of microorganisms in customized media for rapid, accurate antimicrobial susceptibility testing.

公开(公告)号：US20200370086A1

公开(公告)日：2020-11-26

申请号：US16805390

申请日：2020-02-28

Applicant: Accelerate Diagnostics, Inc.

Inventor： Austin Ashby ,  Wayne Showalter ,  Jasmin Cote

IPC: C12Q1/02 ,  G02B7/28 ,  G01N15/06 ,  G01N21/64 ,  B01L3/00 ,  C12Q1/04 ,  G01N1/38 ,  G01N35/02 ,  G01N35/10 ,  H04N5/232

Abstract: A system for automated microorganism identification and antibiotic susceptibility testing comprising a reagent cartridge, a reagent stage, a cassette, a cassette, stage, a pipettor assembly, an optical detection system, and a controller is disclosed. The system is designed to dynamically adjust motor idle torque to control heat load and employs a fast focus process for determining the true focus position of an individual microorganism. The system also may quantify the relative abundance of viable microorganisms in a sample using dynamic dilution, and facilitate growth of microorganisms in customized media for rapid, accurate antimicrobial susceptibility testing.