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公开(公告)号:US20170138913A1
公开(公告)日:2017-05-18
申请号:US15300267
申请日:2014-03-31
Applicant: Agilent Technologies, Inc.
Inventor: Blasius Nocon , Joachim-Richard Wagner , Karsten Lehradt
Abstract: A piston member for a high-pressure pump for pumping fluid in a sample separation apparatus, wherein the piston member comprises a piston configured for being mountable to reciprocate in a piston chamber for displacing fluid, and a sealing for sealing between the piston member and the piston chamber when the piston member is mounted in the piston chamber to reciprocate, wherein the sealing is mounted on the piston so as to reciprocate together with the piston.
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公开(公告)号:US20240410863A1
公开(公告)日:2024-12-12
申请号:US18735742
申请日:2024-06-06
Applicant: Agilent Technologies, Inc.
Inventor: Blasius Nocon , Christoph Geiger
IPC: G01N30/24
Abstract: A sample injector for an analytical device includes a needle seat configured to receive a needle for injecting a sample into an injector path. The needle seat is mounted in a floating manner so that the orientation of the needle seat is aligned automatically with respect to the orientation of the approaching needle. The sample injector may be provided in an analytical device such as a chromatographic device.
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公开(公告)号:US20240272185A1
公开(公告)日:2024-08-15
申请号:US18437876
申请日:2024-02-09
Applicant: Agilent Technologies, Inc.
Inventor: Blasius Nocon , Christoph Geiger
CPC classification number: G01N35/0099 , G01N35/026
Abstract: A sample handling device for handling a sample container, in particular for an analysis device for analyzing a fluidic sample in the sample container, includes: i) a push-push mechanism for fixing and releasing the sample container; and ii) a coupling region for releasably coupling to a sample moving device. The sample handling device is a passive device which is adapted to perform the fixing and the releasing free of a drive, in particular a motor. Furthermore, a related sample handling arrangement, an analysis device, and a method are described.
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公开(公告)号:US20240125744A1
公开(公告)日:2024-04-18
申请号:US18379930
申请日:2023-10-13
Applicant: Agilent Technologies, Inc.
Inventor: Blasius Nocon , Lena Höninger , Christoph Geiger , Axel Reichert , Dirk Göger
CPC classification number: G01N30/30 , G01N30/12 , G01N2030/027
Abstract: A thermostat arrangement for a sample separation device for separating a fluidic sample includes a separation unit thermostat unit for adjusting a temperature of a separation unit for separating the fluidic sample in a mobile phase, a sample handling unit thermostat unit for adjusting the temperature of a sample handling unit for handling the fluidic sample, and a thermal coupling unit for thermally coupling the separation unit thermostat unit with the sample handling unit thermostat unit.
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公开(公告)号:US20230085894A1
公开(公告)日:2023-03-23
申请号:US17801767
申请日:2021-02-26
Applicant: Agilent Technologies, Inc.
Inventor: Blasius Nocon , Thomas Ortmann
Abstract: A sample injector is provided for a chromatography system that includes a mobile phase drive and a separation unit. The mobile phase drive is configured for driving a mobile phase through the separation unit, and the separation unit is configured for chromatographically separating compounds of a sample fluid in the mobile phase. The sample injector is configured for injecting the sample fluid into the mobile phase and comprises a needle and a handling unit configured for positioning the needle. Operating the sample injector includes providing a receptacle that includes a filtration unit configured for filtering a sample fluid comprised within the receptacle, moving the filtration unit within the receptacle in order to filter at least a portion of the sample fluid contained in the receptacle, operating the handling unit to position the needle into the receptacle, and aspirating a volume of the filtered sample fluid.
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公开(公告)号:US20250146984A1
公开(公告)日:2025-05-08
申请号:US18932428
申请日:2024-10-30
Applicant: Agilent Technologies, Inc.
Inventor: Blasius Nocon , Konstantin Shoykhet , Tobias Meier , Karsten Lehradt
Abstract: A sample separation apparatus includes a fluid drive arrangement having a first fluid drive unit and a second fluid drive unit for driving a mobile phase along a flow path to a sample separation unit, a sample accommodation volume configured to accommodate the fluidic sample and to be selectively fluidically coupleable with the flow path or fluidically decoupleable from the flow path, and a control unit configured to control respective operations of the fluid drive units, and to control a fluidically decoupling of the second fluid drive unit from the flow path in a decoupled operation mode of the sample separation apparatus. The control unit is further configured to control, in the decoupled operation mode, the decoupled second fluid drive unit for fluidically coupling to the sample accommodation volume, and intaking sample into the sample accommodation volume.
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公开(公告)号:US20230296571A1
公开(公告)日:2023-09-21
申请号:US18018540
申请日:2021-07-29
Applicant: Agilent Technologies, Inc.
Inventor: Thomas Ortmann , Blasius Nocon , Armin Steinke , Christian Daniel Ruf
IPC: G01N30/20
CPC classification number: G01N30/20 , G01N2030/027
Abstract: A valve may be utilized in a high-performance chromatography system for separating components of a sample liquid introduced into a mobile phase. The valve has a first valve element and a second valve element. By a movement of one valve element relative to the other, a first effective surface of the first valve element is brought into connection with a second effective surface of the second valve element, and a flow path may be produced or suppressed. The second valve element has an elastic region to compensate for an axial angle between the first valve element and the second valve element, such that the first effective surface and the second effective surface may be oriented parallel to each other. This may favorably influence a fluidic leak tightness and/or longevity of the valve.
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公开(公告)号:US10591446B2
公开(公告)日:2020-03-17
申请号:US15300267
申请日:2014-03-31
Applicant: Agilent Technologies, Inc.
Inventor: Blasius Nocon , Joachim-Richard Wagner , Karsten Lehradt
IPC: G01N30/32 , F04B9/00 , F04B9/06 , F04B9/02 , F04B37/12 , F04B13/00 , F04B53/14 , F04B53/16 , F16J1/04 , F16J1/00 , F16J1/06
Abstract: A piston member for a high-pressure pump for pumping fluid in a sample separation apparatus, wherein the piston member comprises a piston configured for being mountable to reciprocate in a piston chamber for displacing fluid, and a sealing for sealing between the piston member and the piston chamber when the piston member is mounted in the piston chamber to reciprocate, wherein the sealing is mounted on the piston so as to reciprocate together with the piston.
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公开(公告)号:US20250137887A1
公开(公告)日:2025-05-01
申请号:US18932291
申请日:2024-10-30
Applicant: Agilent Technologies, Inc.
Inventor: Blasius Nocon , Thomas Ortmann
Abstract: A sample transport device for transporting a fluidic sample, in particular for an analyzer for analyzing the fluidic sample, includes a sample receptacle for receiving and/or dispensing the fluidic sample; a moving device, in particular a robot arm, for moving the sample receptacle, and a pumping element arranged to be moved by the moving device to perform and/or trigger a pumping operation.
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公开(公告)号:US11519885B2
公开(公告)日:2022-12-06
申请号:US17239238
申请日:2021-04-23
Applicant: Agilent Technologies, Inc.
Inventor: Thomas Ortmann , Michael Lang , Blasius Nocon
Abstract: A sample injector for a chromatography system is configured for injecting a sample fluid into a mobile phase, and includes a needle and a conduit. The needle is configured for aspirating the sample fluid and includes a needle tip, a needle channel through the needle for guiding the aspirated sample fluid, and a needle opening at the needle tip into which the needle channel opens. The conduit is configured for fluidically coupling with the needle and includes a conduit tip, and a conduit channel through the conduit for guiding fluid and having a conduit opening at the conduit tip. The conduit tip and the needle tip are configured to be pressed against each other for fluidically coupling the conduit channel with the needle channel, with at least a portion of the conduit tip penetrating into the needle opening for providing the fluidic coupling between the conduit and needle channels.
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