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公开(公告)号:US12163932B2
公开(公告)日:2024-12-10
申请号:US17312888
申请日:2018-12-14
Applicant: Agilent Technologies, Inc.
Inventor: Thomas Ortmann
Abstract: A configurable injector for injecting a fluidic sample in a separation path of a sample separation apparatus includes a sample accommodation volume for accommodating the fluidic sample to be injected into the separation path, a valve arrangement fluidically couplable with the separation path, fluidically coupled with the sample accommodation volume, and being controllable for injecting the fluidic sample into the separation path, an input interface configured for receiving input data indicative of an injection profile of an injector to be emulated by the configurable injector, and a control unit configured for controlling the configurable injector, in particular the valve arrangement, so that the configurable injector is operated in accordance with the injection profile to thereby emulate the injector to be emulated.
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公开(公告)号:US12078619B2
公开(公告)日:2024-09-03
申请号:US17288478
申请日:2018-10-26
Applicant: Agilent Technologies, Inc.
Inventor: Thomas Ortmann
CPC classification number: G01N30/20 , B01D15/1885 , G01N30/22 , G01N30/466 , G01N30/6043 , G01N2030/202 , G01N2030/207
Abstract: An injector, for injecting a fluidic sample in at least one selected one of a first sample separation apparatus and a second sample separation apparatus, includes a valve arrangement fluidically connectable to the first sample separation apparatus and the second sample separation apparatus, a sample accommodation volume for accommodating the fluidic sample, and a control unit configured for controlling the valve arrangement so that fluidic sample in the sample accommodation volume is selectively injectable into the selected first sample separation apparatus and/or second sample separation apparatus.
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公开(公告)号:US11946913B2
公开(公告)日:2024-04-02
申请号:US17730553
申请日:2022-04-27
Applicant: Agilent Technologies, Inc.
Inventor: Thomas Ortmann , Martin Seifried , Sam Wouters , Irina Spuling
CPC classification number: G01N30/20 , G01N30/14 , G01N30/32 , G01N2030/027 , G01N2030/326
Abstract: An injector is configured for injecting a fluidic sample from an injector path into a mobile phase in a separation path between a fluid drive and a sample separation unit of a sample separation device. The injector includes a control unit configured for generating a first overpressure in a blocked first partial path of the injector path by a first pressure source, for generating a second overpressure in a blocked second partial path of the injector path by a second pressure source, for subsequently fluidically coupling the first partial path with the second partial path for generating an expansion stroke for releasing a gas bubble in the injector path, and for rinsing the released gas bubble from the injector path.
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公开(公告)号:US20230210420A1
公开(公告)日:2023-07-06
申请号:US18011127
申请日:2021-06-22
Applicant: Agilent Technologies, Inc.
Inventor: Thomas Ortmann , Michael Lang
Abstract: A sampling unit includes a needle for aspirating a sample fluid, a housing, and a fitting. The needle includes a needle tip and a needle channel through the needle for guiding the aspirated sample fluid. The needle channel opens at the needle tip. The housing includes a housing cavity and a housing channel opening into the housing cavity. The fitting includes a fitting cavity and a fitting channel. The fitting is configured for sealingly receiving the needle tip into the fitting cavity and for being inserted into the housing cavity, so that the fitting channel on one side fluidically couples to the needle channel and on another side couples to the housing channel.
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公开(公告)号:US20200276728A1
公开(公告)日:2020-09-03
申请号:US16765452
申请日:2018-11-19
Applicant: Agilent Technologies, Inc.
Inventor: Darijo Zeko , Tony Ziegler , Thomas Ortmann
IPC: B28B1/00 , G01N30/60 , G01N30/20 , B33Y80/00 , B33Y10/00 , B33Y70/00 , C04B35/10 , C04B35/48 , B01L3/00
Abstract: A microfluidic component for a sample separation apparatus includes a component body including ceramic and at least one microfluidic structure in the component body. The component body is manufactured by additive manufacturing, in particular by three-dimensional printing.
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公开(公告)号:US20190390788A1
公开(公告)日:2019-12-26
申请号:US16480600
申请日:2018-01-23
Applicant: Agilent Technologies, Inc.
Inventor: Tony Ziegler , Darijo Zeko , Thomas Ortmann
IPC: F16K25/00 , F16K11/074 , F16K3/04 , G01N30/20
Abstract: A fluid valve for a sample separation apparatus includes a first valve component and a second valve component, which are adjacent to one another and movable relative to one another. The valve components are configured such that, in at least one switching state, at least one switchable fluid channel is formed between the valve components, and at least one part of a surface of at least one of the first valve component and the second valve component is provided with a coating containing gold and/or platinum.
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公开(公告)号:US10371671B2
公开(公告)日:2019-08-06
申请号:US15608888
申请日:2017-05-30
Applicant: Agilent Technologies, Inc.
Inventor: Thomas Ortmann , Daniel Thielsch
Abstract: A sample management device which comprises a source flow path in which a fluidic sample can flow, a volume flow adjustment unit configured to adjust a volume flow of the fluidic sample to be branched off from the source flow path at a fluidic coupling point, and a fluidic valve fluidically coupled with the source flow path and with the volume flow adjustment unit, wherein the fluidic valve is switchable into a branch off state in which the fluidic coupling point is established within the source flow path to branch off an adjustable volume of the fluidic sample from the source flow path via the fluidic coupling point while a flow of the fluidic sample in the source flow path continues.
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公开(公告)号:US20250137887A1
公开(公告)日:2025-05-01
申请号:US18932291
申请日:2024-10-30
Applicant: Agilent Technologies, Inc.
Inventor: Blasius Nocon , Thomas Ortmann
Abstract: A sample transport device for transporting a fluidic sample, in particular for an analyzer for analyzing the fluidic sample, includes a sample receptacle for receiving and/or dispensing the fluidic sample; a moving device, in particular a robot arm, for moving the sample receptacle, and a pumping element arranged to be moved by the moving device to perform and/or trigger a pumping operation.
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公开(公告)号:US20240241086A1
公开(公告)日:2024-07-18
申请号:US18562216
申请日:2022-05-17
Applicant: Agilent Technologies, Inc.
Inventor: Thomas Ortmann , Dominik Ruf
CPC classification number: G01N30/22 , G01N2030/201 , G01N2030/202 , G01N2030/204 , G01N2030/207
Abstract: A switching unit is configured for selectively fluidically coupling a sampling volume, a sampling drive, a mobile phase drive, and a separating device. In a sample load configuration, the switching unit is configured for fluidically coupling the sampling volume and the sampling drive, for moving the fluidic sample into the sampling volume. In a decouple configuration, the switching unit is configured for fluidically coupling the sampling volume between the sampling drive and the separating device, while the mobile phase drive is fluidically decoupled from the separating device. In a sample introduction configuration, the switching unit is configured for fluidically coupling the mobile phase drive, the sampling volume, and the separating device for introducing at least an amount of the fluidic sample stored in the sampling volume into the mobile phase for fluid separation by the separating device.
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公开(公告)号:US11931918B2
公开(公告)日:2024-03-19
申请号:US16765452
申请日:2018-11-19
Applicant: Agilent Technologies, Inc.
Inventor: Darijo Zeko , Tony Ziegler , Thomas Ortmann
IPC: B28B1/00 , B01L3/00 , B33Y10/00 , B33Y70/00 , B33Y80/00 , C04B35/10 , C04B35/48 , G01N30/20 , G01N30/60
CPC classification number: B28B1/001 , B01L3/502707 , B33Y10/00 , B33Y70/00 , B33Y80/00 , C04B35/10 , C04B35/48 , G01N30/20 , G01N30/6095 , C04B2235/666 , C04B2235/667 , G01N2030/202
Abstract: A microfluidic component for a sample separation apparatus includes a component body including ceramic and at least one microfluidic structure in the component body. The component body is manufactured by additive manufacturing, in particular by three-dimensional printing.
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