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公开(公告)号：US09879234B2
公开(公告)日：2018-01-30
申请号：US14416981
申请日：2013-07-30
Applicant: BASF PLANT SCIENCE COMPANY GMBH
Inventor： Laurent Marty , Toralf Senger
CPC classification number: C12N9/0071 , C12N9/001 , C12P7/6427 , C12Y114/19
Abstract: The invention provides nucleic acid molecules which encodes a novel fatty acid desaturase, KCS, KCR and/or LACS from Thraustochytrium aureum and Sphaeroforma arctica. The invention also provides recombinant expression vectors containing the nucleic acid molecules, host cells into which the expression vectors have been introduced, and methods for large-scale production of long chain polyunsaturated fatty acids (LCPUFAs), e.g., ARA, EPA and DHA and for screening for delta-4 desaturases.
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公开(公告)号：US11613761B1
公开(公告)日：2023-03-28
申请号：US15526550
申请日：2015-11-13
Inventor： Toralf Senger , Laurent Marty , Irene Kunze , Heiko Haertel , Steven Craig Bremmer , Steven D. Breazeale , Joerg Bauer , Patricia Vrinten , Sten Stymne , Jenny Lindberg Yilmaz , John A. McElver , Dietrich Rein , Carl Andre
Abstract: T-DNA for expression of a target gene in a plant, wherein the T-DNA comprises a left and a right border element and at least one expression cassette comprising a promoter, operatively linked thereto a target gene, and downstream thereof a terminator, wherein the length of the T-DNA, measured from left to right border element and comprising the target gene, has a length of at least 30000 bp.
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公开(公告)号：US20210308202A1
公开(公告)日：2021-10-07
申请号：US17346522
申请日：2021-06-14
Applicant: BASF PLANT SCIENCE COMPANY GMBH
Inventor： Toralf Senger , Laurent Marty , Irene Kunze , Dietrich Rein , Jörg Bauer , Carl Andre
IPC: A61K36/31 , C12Q1/6895
Abstract: The present invention provides transgenic Brassica events LBFLFK and LBFDAU and progeny thereof, and cells, seeds, plants comprising DNA diagnostic for these events. The invention also provides artificial oligonucleotide primers and probes that are diagnostic for the LBFLFK and LBFDAU events and their progeny in a sample, and methods for detecting the presence of the LBFLFK and LBFDAU events and their progeny in a sample. The invention further provides oil and commodity products derived from the LBFLFK and LBFDAU events.
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公开(公告)号：US10208270B2
公开(公告)日：2019-02-19
申请号：US15159931
申请日：2016-05-20
Applicant: BASF Plant Science Company GmbH
Inventor： Toralf Senger , Laurent Marty , Sten Stymne , Jenny Lindberg Yilmaz , Johnathan A. Napier , Olga Sayanova , Richard Haslam , Ruiz Lopez Noemi
IPC: C12N15/82 , C11C1/04 , A23D9/02 , C12P7/64 , A23K20/158 , A23L33/105 , A23L33/115 , A23L33/12
Abstract: The present invention relates to the recombinant manufacture of polyunsaturated fatty acids. Specifically, it relates to acyltransferase polypeptides, polynucleotides encoding said acyltransferases as well as vectors, host cells, non-human transgenic organisms containing said polynucleotides. Moreover, the present invention contemplates methods for the manufacture of polyunsaturated fatty acids as well as oils obtained by such methods.
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公开(公告)号：US20230293615A1
公开(公告)日：2023-09-21
申请号：US18162300
申请日：2023-01-31
Inventor： Toralf Senger , Laurent Marty , Irene Kunze , Heiko Haertel , Steven Craig Bremmer , Steven D. Breazeale , Joerg Bauer , Patricia Vrinten , Sten Stymne , Jenny Lindberg Yilmaz , John A. McElver , Dietrich Rein , Carl Andre
IPC: A61K36/31 , C12Q1/6895
CPC classification number: A61K36/31 , C12Q1/6895 , C12N15/8247
Abstract: T-DNA for expression of a target gene in a plant, wherein the T-DNA comprises a left and a right border element and at least one expression cassette comprising a promoter, operatively linked thereto a target gene, and downstream thereof a terminator, wherein the length of the T-DNA, measured from left to right border element and comprising the target gene, has a length of at least 30000 bp.
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Patent Agency Ranking
公开(公告)号：US11033593B2
公开(公告)日：2021-06-15
申请号：US15526443
申请日：2015-11-13
Applicant: BASF PLANT SCIENCE COMPANY GMBH
Inventor： Toralf Senger , Laurent Marty , Irene Kunze , Dietrich Rein , Joerg Bauer , Carl Andre
IPC: A61K36/31 , C12N15/82 , C12Q1/6895 , C12N9/02 , C12N9/00 , A61K31/202
Abstract: The present invention provides transgenic Brassica events LBFLFK and LBFDAU and progeny thereof, and cells, seeds, plants comprising DNA diagnostic for these events. The invention also provides artificial oligonucleotide primers and probes that are diagnostic for the LBFLFK and LBFDAU events and their progeny in a sample, and methods for detecting the presence of the LBFLFK and LBFDAU events and their progeny in a sample. The invention further provides oil and commodity products derived from the LBFLFK and LBFDAU events.
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公开(公告)号：US11813302B2
公开(公告)日：2023-11-14
申请号：US17346522
申请日：2021-06-14
Applicant: BASF PLANT SCIENCE COMPANY GMBH
Inventor： Toralf Senger , Laurent Marty , Irene Kunze , Dietrich Rein , Jörg Bauer , Carl Andre
IPC: A61K36/31 , C12Q1/6895 , C12N15/82 , C12N9/02 , C12N9/00 , A61K31/202
CPC classification number: A61K36/31 , C12Q1/6895 , A61K31/202 , C12N9/0071 , C12N9/93 , C12N15/8247 , C12Y114/19 , C12Y114/19003 , C12Y114/19006 , C12Y602/01003
Abstract: The present invention provides transgenic Brassica events LBFLFK and LBFDAU and progeny thereof, and cells, seeds, plants comprising DNA diagnostic for these events. The invention also provides artificial oligonucleotide primers and probes that are diagnostic for the LBFLFK and LBFDAU events and their progeny in a sample, and methods for detecting the presence of the LBFLFK and LBFDAU events and their progeny in a sample. The invention further provides oil and commodity products derived from the LBFLFK and LBFDAU events.
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公开(公告)号：US20150203826A1
公开(公告)日：2015-07-23
申请号：US14416981
申请日：2013-07-30
Inventor： Laurent Marty , Toralf Senger
CPC classification number: C12N9/0071 , C12N9/001 , C12P7/6427 , C12Y114/19
Abstract: The invention provides nucleic acid molecules which encodes a novel fatty acid desaturase, KCS, KCR and/or LACS from Thraustochytrium aureum and Sphaeroforma arctica. The invention also provides recombinant expression vectors containing said nucleic acid molecules, host cells into which the expression vectors have been introduced, and methods for large-scale production of long chain polyunsaturated fatty acids (LCPUFAs), e.g., ARA, EPA and DHA and for screening for delta-4 desaturases.
Abstract translation: 本发明提供了编码来自Thraustochytrium aureum和Sphaeroforma arctica的新型脂肪酸去饱和酶，KCS，KCR和/或LACS的核酸分子。 本发明还提供含有所述核酸分子的重组表达载体，已经引入表达载体的宿主细胞，以及用于大规模生产长链多不饱和脂肪酸（LCPUFA）的方法，例如ARA，EPA和DHA，以及用于 筛选Δ-4去饱和酶。
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公开(公告)号：US10119126B2
公开(公告)日：2018-11-06
申请号：US15864798
申请日：2018-01-08
Applicant: BASF PLANT SCIENCE COMPANY GMBH
Inventor： Laurent Marty , Toralf Senger
Abstract: The invention provides nucleic acid molecules which encodes a novel fatty acid desaturase, KCS, KCR and/or LACS from Thraustochytrium aureum and Sphaeroforma arctica. The invention also provides recombinant expression vectors containing the nucleic acid molecules, host cells into which the expression vectors have been introduced, and methods for large-scale production of long chain polyunsaturated fatty acids (LCPUFAs), e.g., ARA, EPA and DHA and for screening for delta-4 desaturases.
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公开(公告)号：US20180142217A1
公开(公告)日：2018-05-24
申请号：US15864798
申请日：2018-01-08
Applicant: BASF PLANT SCIENCE COMPANY GMBH
Inventor： Laurent Marty , Toralf Senger
CPC classification number: C12N9/0071 , C12N9/001 , C12P7/6427 , C12Y114/19
Abstract: The invention provides nucleic acid molecules which encodes a novel fatty acid desaturase, KCS, KCR and/or LACS from Thraustochytrium aureum and Sphaeroforma arctica. The invention also provides recombinant expression vectors containing said nucleic acid molecules, host cells into which the expression vectors have been introduced, and methods for large-scale production of long chain polyunsaturated fatty acids (LCPUFAs), e.g., ARA, EPA and DHA and for screening for delta-4 desaturases.
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