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公开(公告)号:US11484278B2
公开(公告)日:2022-11-01
申请号:US14774577
申请日:2014-03-12
Applicant: Biogen MA Inc.
Inventor: Ajay Verma , Jack Hoppin , Jacob Hesterman
Abstract: Wearable apparatus and method of using same for tracking a labeled probe in a subject are disclosed.
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公开(公告)号:US10206639B2
公开(公告)日:2019-02-19
申请号:US15275154
申请日:2016-09-23
Applicant: Biogen MA Inc.
Inventor: Ajay Verma , Marisa J. Bober , Victoria Cabot , Courtney D. Hilliard , Ara N. Knaian , Seth O. Newburg , John William Hoppin , Karl F. Schmidt
Abstract: Various embodiments of medical detector systems as well as their methods of operation are disclosed. In one embodiment, one or more detectors are coupled to wearable structures for detecting at least a first tracer within a body portion. In another embodiment, one or more detectors are coupled to a wearable structure, where the detector corresponds to a CMOS chip that directly detects a first radioactive tracer.
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公开(公告)号:US11040119B2
公开(公告)日:2021-06-22
申请号:US14774510
申请日:2014-03-12
Applicant: Biogen MA Inc.
Inventor: Ajay Verma , Jack Hoppin
Abstract: The invention provides compositions and methods for evaluating neuromuscular function in a subject, e.g., a subject at risk for or suffering from a neuromuscular disorder.
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公开(公告)号:USD795890S1
公开(公告)日:2017-08-29
申请号:US29542796
申请日:2015-10-16
Applicant: Biogen MA Inc.
Designer: Ajay Verma , John W. Hoppin , Karl F. Schmidt
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公开(公告)号:US20180289655A1
公开(公告)日:2018-10-11
申请号:US15559265
申请日:2016-03-18
Applicant: Biogen MA Inc.
Inventor: Ajay Verma , Robert Scannevin , Shyam Karki , Fengmei Zheng
IPC: A61K31/225 , A61K47/40 , A61K9/00
Abstract: Disclosed herein are methods and compositions for the intravenous administration of fumarates for the treatment of neurological diseases, such as stroke, amyotrophic lateral sclerosis, Huntington's disease, Alzheimer's disease, Parkinson's disease, and Multiple Sclerosis.
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公开(公告)号:US20160029983A1
公开(公告)日:2016-02-04
申请号:US14774577
申请日:2014-03-12
Applicant: BIOGEN MA INC.
Inventor: Ajay Verma , Jack Hoppin , Jacob Hesterman
CPC classification number: A61B6/4405 , A61B5/0022 , A61B5/0035 , A61B5/0042 , A61B5/0071 , A61B5/02755 , A61B5/4088 , A61B5/6801 , A61B6/037 , A61B6/4216 , A61B6/4258 , A61B6/481 , A61B6/501 , A61B6/563 , A61K51/1096 , G16H40/67
Abstract: Wearable apparatus and method of using same for tracking a labeled probe in a subject are disclosed.
Abstract translation: 公开了可佩戴的装置及其使用方法来跟踪受试者中的标记探针。
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公开(公告)号:US11660054B2
公开(公告)日:2023-05-30
申请号:US16462518
申请日:2017-11-22
Applicant: Biogen MA Inc.
Inventor: Ajay Verma , Elliot Greenblatt , Ira Spool , Seth O. Newburg , Guy M. Danner , Ara N. Knaian , Rachel M. Chaney , John W. Hoppin
CPC classification number: A61B6/037 , A61B5/6803 , A61B5/6805 , A61B6/4258 , A61B6/4266 , G01T1/16
Abstract: Embodiments related to methods and wearable medical detecting systems for detecting disease states and/or treatment states of a subject are described. In one embodiment, a wearable structure may include one or more radiation detectors use to detect a time varying radiation signal emitted from a labeled compound within a body portion of interest. The radiation signal may be analyzed to determine one or more signal characteristics that may be compared to one or more predetermined standard characteristics associated with known disease and/or treatment states to determine a current disease and/or treatment state of a subject.
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公开(公告)号:US11147524B2
公开(公告)日:2021-10-19
申请号:US16229671
申请日:2018-12-21
Applicant: Biogen MA Inc.
Inventor: Ajay Verma , Marisa J. Bober , Victoria Cabot , Courtney D. Hilliard , Ara N. Knaian , Seth O. Newburg , John William Hoppin , Karl F. Schmidt
IPC: A61B5/0275 , A61B6/00 , A61B5/00 , A61B6/03 , A61B6/04
Abstract: Various embodiments of medical detector systems as well as their methods of operation are disclosed. In one embodiment, one or more detectors are coupled to wearable structures for detecting at least a first tracer within a body portion. In another embodiment, one or more detectors are coupled to a wearable structure, where the detector corresponds to a CMOS chip that directly detects a first radioactive tracer.
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公开(公告)号:US20190200943A1
公开(公告)日:2019-07-04
申请号:US16229671
申请日:2018-12-21
Applicant: Biogen MA Inc.
Inventor: Ajay Verma , Marisa J. Bober , Victoria Cabot , Courtney D. Hilliard , Ara N. Knaian , Seth O. Newburg , John William Hoppin , Karl F. Schmidt
IPC: A61B6/00 , A61B5/00 , A61B6/03 , A61B6/04 , A61B5/0275
CPC classification number: A61B6/4405 , A61B5/0024 , A61B5/0275 , A61B5/6803 , A61B5/6805 , A61B6/037 , A61B6/04 , A61B6/4258 , A61B6/4266 , A61B6/4275 , A61B6/4429 , A61B6/481 , A61B6/501 , A61B6/506
Abstract: Various embodiments of medical detector systems as well as their methods of operation are disclosed. In one embodiment, one or more detectors are coupled to wearable structures for detecting at least a first tracer within a body portion. In another embodiment, one or more detectors are coupled to a wearable structure, where the detector corresponds to a CMOS chip that directly detects a first radioactive tracer.
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公开(公告)号:US20170360699A1
公开(公告)日:2017-12-21
申请号:US15536508
申请日:2015-12-17
Applicant: Biogen MA Inc.
Inventor: Ajay Verma
CPC classification number: A61K9/0085 , A61H9/00 , A61H9/0021 , A61H9/0028 , A61H9/005 , A61H9/0078 , A61H9/0092 , A61H23/00 , A61H23/0245 , A61H31/00 , A61H2201/0103 , A61H2201/0149 , A61H2201/1619 , A61H2201/165 , A61H2201/5002 , A61H2205/08 , A61K9/0019
Abstract: Methods and apparatuses for dispersing a compound within the patient are described. In one embodiment, an effective amount of a compound may be present in the cerebrospinal fluid of a patient and a force may be applied to the torso of the patient sufficient to enhance the convection of the cerebrospinal fluid. In another embodiment, a bolus including a compound may be injected into the cerebrospinal fluid of a patient. The volume of the bolus may be between about 5% and 30% of the total volume of the cerebrospinal fluid of the patient.
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