公开(公告)号：US11111269B2

公开(公告)日：2021-09-07

申请号：US16005642

申请日：2018-06-11

Applicant: Biogen MA Inc.

Inventor： Sanchayita Ghose ,  Yinying Tao

IPC: C07K1/22 ,  C07K16/06 ,  C07K1/20

Abstract: Various aspects and embodiments of the present disclosure relate to the purification antibodies by hydrophobic interaction chromatography under no-salt conditions.

公开(公告)号：US09994609B2

公开(公告)日：2018-06-12

申请号：US14775774

申请日：2014-03-15

Applicant: Biogen MA Inc.

Inventor： Sanchayita Ghose ,  Yinying Tao

IPC: C07K1/20 ,  C07K16/06

CPC classification number: C07K1/20 ,  C07K16/065

Abstract: Various aspects and embodiments of the present disclosure relate to the purification antibodies by hydrophobic interaction chromatography under no-salt conditions.

公开(公告)号：US20190144495A1

公开(公告)日：2019-05-16

申请号：US16005642

申请日：2018-06-11

Applicant: Biogen MA Inc.

Inventor： Sanchayita Ghose ,  Yinying Tao

IPC: C07K1/20 ,  C07K16/06

Abstract: Various aspects and embodiments of the present disclosure relate to the purification antibodies by hydrophobic interaction chromatography under no-salt conditions.

公开(公告)号：US20190175738A1

公开(公告)日：2019-06-13

申请号：US16211302

申请日：2018-12-06

Applicant: Biogen MA Inc.

Inventor： Lynn Edward Conley ,  Yinying Tao

IPC: A61K47/20 ,  A61K47/24 ,  C12N7/00 ,  A61K47/18 ,  A61K38/17 ,  A61K9/00 ,  C07K14/705

CPC classification number: A61K47/20 ,  A61K9/0019 ,  A61K38/1793 ,  A61K47/186 ,  A61K47/24 ,  C07K14/70578 ,  C07K2319/30 ,  C12N7/00 ,  C12N2710/16763 ,  C12N2740/13063

Abstract: Aspects of the invention provide therapeutic recombinant protein preparations and methods of preparing therapeutic recombinant protein, which methods include contacting recombinant protein preparations with zwitterionic detergent at or above critical micelle concentration of the detergent.

公开(公告)号：US20160024145A1

公开(公告)日：2016-01-28

申请号：US14775774

申请日：2014-03-15

Applicant: BIOGEN MA INC.

Inventor： Sanchayita Ghose ,  Yinying Tao

IPC: C07K1/20

CPC classification number: C07K1/20 ,  C07K16/065

Abstract: Various aspects and embodiments of the present disclosure relate to the purification antibodies by hydrophobic interaction chromatography under no-salt conditions.

Abstract translation: 本公开的各个方面和实施方案涉及通过在无盐条件下的疏水相互作用层析纯化抗体。

公开(公告)号：US20230391820A1

公开(公告)日：2023-12-07

申请号：US18330783

申请日：2023-06-07

Applicant: Biogen MA Inc.

Inventor： Sanchayita Ghose ,  Yinying Tao

IPC: C07K1/20 ,  C07K16/06

CPC classification number: C07K1/20 ,  C07K16/065

Abstract: Various aspects and embodiments of the present disclosure relate to the purification antibodies by hydrophobic interaction chromatography under no-salt conditions.

公开(公告)号：US10702603B2

公开(公告)日：2020-07-07

申请号：US16211302

申请日：2018-12-06

Applicant: Biogen MA Inc.

Inventor： Lynn Edward Conley ,  Yinying Tao

IPC: A61K38/00 ,  A61K47/20 ,  A61K9/00 ,  A61K47/24 ,  C07K14/705 ,  C12N7/00 ,  A61K47/18 ,  A61K38/17

Abstract: Aspects of the invention provide therapeutic recombinant protein preparations and methods of preparing therapeutic recombinant protein, which methods include contacting recombinant protein preparations with zwitterionic detergent at or above critical micelle concentration of the detergent.

公开(公告)号：US10188732B2

公开(公告)日：2019-01-29

申请号：US14419968

申请日：2013-08-06

Applicant: Biogen MA Inc.

Inventor： Lynn Edward Conley ,  Yinying Tao

IPC: A61K38/00 ,  A61K47/20 ,  C12N7/00 ,  A61K9/00 ,  A61K47/24 ,  A61K38/17 ,  A61K47/18 ,  C07K14/705

Abstract: Aspects of the invention provide therapeutic recombinant protein preparations and methods of preparing therapeutic recombinant protein, which methods include contacting recombinant protein preparations with zwitterionic detergent at or above critical micelle concentration of the detergent.