公开(公告)号：US10092180B2

公开(公告)日：2018-10-09

申请号：US15810939

申请日：2017-11-13

Applicant: Bioptigen, Inc.

Inventor： Robert H. Hart ,  Eric L. Buckland ,  Glenn A. Myers ,  Joseph A. Izatt ,  Joseph Elliott Vance

IPC: A61B3/14 ,  A61B3/10 ,  G02B26/10 ,  A61B5/00

Abstract: OCT imaging systems are provided for imaging a spherical-type eye including a source having an associated source arm path and a reference arm having an associated reference arm path coupled to the source path. The reference arm path has an associated reference arm path length. A sample is also provided having an associated sample arm path coupled to the source arm and reference arm paths. A lens having a focal power optimized for a diameter of the spherical-type eye is provided along with a reference arm path length adjustment module coupled to the reference arm. The reference arm path length adjustment module is configured to automatically adjust the reference arm path length such that the reference arm path length is based on an eye diameter of the subject.

公开(公告)号：US10060720B2

公开(公告)日：2018-08-28

申请号：US15386692

申请日：2016-12-21

Applicant: Bioptigen, Inc.

Inventor： Joseph A. Izatt ,  Eric L. Buckland ,  William J. Brown

IPC: G01B9/02 ,  A61B3/10 ,  A61B3/12

CPC classification number: G01B9/02044 ,  A61B3/102 ,  A61B3/1225 ,  A61B5/0066 ,  G01B9/02004 ,  G01B9/02007 ,  G01B9/02008 ,  G01B9/02091 ,  G01B2290/45 ,  G01N21/4795

Abstract: Frequency domain optical coherence imaging systems have an optical source, an optical detector and an optical transmission path between the optical source and the optical detector. The optical transmission path between the optical source and the optical detector reduces an effective linewidth of the imaging system. The optical source may be a broadband source and the optical transmission path may include a periodic optical filter.

公开(公告)号：US20170102223A1

公开(公告)日：2017-04-13

申请号：US15386692

申请日：2016-12-21

Applicant: Bioptigen, Inc.

Inventor： Joseph A. Izatt ,  Eric L. Buckland ,  William J. Brown

IPC: G01B9/02 ,  A61B3/12 ,  A61B3/10

CPC classification number: G01B9/02044 ,  A61B3/102 ,  A61B3/1225 ,  A61B5/0066 ,  G01B9/02004 ,  G01B9/02007 ,  G01B9/02008 ,  G01B9/02091 ,  G01B2290/45 ,  G01N21/4795

Abstract: Frequency domain optical coherence imaging systems have an optical source, an optical detector and an optical transmission path between the optical source and the optical detector. The optical transmission path between the optical source and the optical detector reduces an effective linewidth of the imaging system. The optical source may be a broadband source and the optical transmission path may include a periodic optical filter.

公开(公告)号：US20130235344A1

公开(公告)日：2013-09-12

申请号：US13862987

申请日：2013-04-15

Applicant: BIOPTIGEN, INC.

Inventor： Eric L. Buckland ,  Robert H. Hart ,  Glenn A. Myers ,  Joseph A. Izatt

IPC: A61B3/10

CPC classification number: A61B3/102 ,  A61B5/0066 ,  A61B5/0073 ,  G01B9/02054 ,  G01B9/02063 ,  G01B9/02064 ,  G01B9/02091

Abstract: Optical coherence tomography (OCT) imaging systems for imaging an eye are provided including a source having an associated source arm path and a reference arm having an associated reference arm path coupled to the source path, the reference arm path having an associated reference arm path length. A sample having an associated sample arm path coupled to the source arm and reference arm paths is provided. A reference arm path length adjustment module is coupled to the reference arm. The reference arm path length adjustment module is configured to automatically adjust the reference arm path length such that the reference arm path length is based on an eye length of the subject. Related methods and computer program products are also provided.

Abstract translation: 提供了用于对眼睛进行成像的光学相干断层摄影（OCT）成像系统，包括具有相关联的源臂路径的源和具有耦合到源路径的相关参考臂路径的参考臂，该参考臂路径具有相关联的参考臂路径长度 。 提供具有耦合到源臂和参考臂路径的相关联的样本臂路径的样本。 参考臂路径长度调节模块耦合到参考臂。 参考臂路径长度调节模块被配置为自动调整参考臂路径长度，使得参考臂路径长度基于被摄体的眼睛长度。 还提供了相关方法和计算机程序产品。

公开(公告)号：US20140293223A1

公开(公告)日：2014-10-02

申请号：US14301670

申请日：2014-06-11

Applicant: Bioptigen, Inc.

Inventor： Robert H. Hart ,  Eric L. Buckland ,  Glenn A. Myers ,  Joseph A. Izatt ,  Joseph Elliott Vance

IPC: A61B3/10

CPC classification number: A61B3/102 ,  A61B5/0066 ,  A61B5/0073 ,  G02B26/105

Abstract: OCT imaging systems are provided for imaging a spherical-type eye including a source having an associated source arm path and a reference arm having an associated reference arm path coupled to the source path. The reference arm path has an associated reference arm path length. A sample is also provided having an associated sample arm path coupled to the source arm and reference arm paths. A lens having a focal power optimized for a diameter of the spherical-type eye is provided along with a reference arm path length adjustment module coupled to the reference arm. The reference arm path length adjustment module is configured to automatically adjust the reference arm path length such that the reference arm path length is based on an eye diameter of the subject.

Abstract translation: 提供OCT成像系统用于对球形眼睛进行成像，该眼球包括具有相关联的源臂路径的源和具有耦合到源路径的相关参考臂路径的参考臂。 参考臂路径具有相关联的参考臂路径长度。 还提供具有与源臂和参考臂路径相连的相关联的样本臂路径的样本。 具有针对球形眼的直径优化的聚焦功率的透镜与连接到参考臂的参考臂路径长度调节模块一起提供。 参考臂路径长度调节模块被配置为自动调整参考臂路径长度，使得参考臂路径长度基于被摄体的眼睛直径。

公开(公告)号：US20140125952A1

公开(公告)日：2014-05-08

申请号：US14154782

申请日：2014-01-14

Applicant: Bioptigen, Inc.

Inventor： Eric L. Buckland ,  Robert H. Hart ,  Glenn A. Myers ,  Joseph A. Izatt

IPC: A61B3/10

CPC classification number: A61B3/102 ,  A61B5/0066 ,  A61B5/0073 ,  G01B9/02054 ,  G01B9/02063 ,  G01B9/02064 ,  G01B9/02091

Abstract: Optical coherence tomography (OCT) imaging systems for imaging an eye are provided including a source having an associated source arm path and a reference arm having an associated reference arm path coupled to the source path, the reference arm path having an associated reference arm path length. A sample having an associated sample arm path coupled to the source arm and reference arm paths is provided. A reference arm path length adjustment module is coupled to the reference arm. The reference arm path length adjustment module is configured to automatically adjust the reference arm path length such that the reference arm path length is based on an eye length of the subject. Related methods and computer program products are also provided.

Abstract translation: 提供了用于成像眼睛的光学相干断层摄影（OCT）成像系统，包括具有相关联的源臂路径的源和具有耦合到源路径的相关联的参考臂路径的参考臂，参考臂路径具有相关联的参考臂路径长度 。 提供具有耦合到源臂和参考臂路径的相关联的样本臂路径的样本。 参考臂路径长度调节模块耦合到参考臂。 参考臂路径长度调节模块被配置为自动调整参考臂路径长度，使得参考臂路径长度基于被摄体的眼睛长度。 还提供了相关方法和计算机程序产品。

公开(公告)号：US20130120710A1

公开(公告)日：2013-05-16

申请号：US13733263

申请日：2013-01-03

Applicant: Bioptigen, Inc.

Inventor： Eric L. Buckland ,  Joseph A. Izatt ,  William J. Brown

IPC: A61B3/14

CPC classification number: A61B3/14 ,  A61B3/1005 ,  A61B3/102 ,  A61B3/1208 ,  A61B3/1225 ,  A61B3/125 ,  G01B9/02028 ,  G01B9/0205 ,  G01B9/02057 ,  G01B9/02089 ,  G01B9/02091 ,  G01B2290/25 ,  G01B2290/35 ,  G01N21/4795

Abstract: Portable optical coherence tomography (OCT) devices including at least one mirror configured to scan at least two directions are provided. The portable OCT devices are configured to provide a portable interface to a sample that can be aligned to the sample without repositioning the sample. Related systems are also provided.

Abstract translation: 提供了包括配置成扫描至少两个方向的至少一个反射镜的便携式光学相干断层摄影（OCT）装置。 便携式OCT设备被配置为向样本提供便携式接口，该样本可以与样品对准而不重新定位样品。 还提供了相关系统。

公开(公告)号：US09867536B2

公开(公告)日：2018-01-16

申请号：US15042592

申请日：2016-02-12

Applicant: Bioptigen, Inc.

Inventor： Joseph A. Izatt ,  Eric L. Buckland ,  Bradley A. Bower ,  Robert H. Hart

IPC: A61B3/10 ,  G01B9/02 ,  A61B3/117 ,  A61B3/12

CPC classification number: A61B3/102 ,  A61B3/117 ,  A61B3/1225 ,  G01B9/0201 ,  G01B9/02078 ,  G01B9/02091

Abstract: Optical coherence tomography systems for imaging a whole eye are provided including a sample arm including focal optics that are configured to rapidly switch between at least two scanning modes in less than about 1.0 second.

公开(公告)号：US09814383B2

公开(公告)日：2017-11-14

申请号：US15464568

申请日：2017-03-21

Applicant: Bioptigen, Inc.

Inventor： Robert H. Hart ,  Eric L. Buckland ,  Glenn A. Myers ,  Joseph A. Izatt ,  Joseph Elliott Vance

IPC: A61B3/14 ,  A61B3/10 ,  G02B26/10

CPC classification number: A61B3/102 ,  A61B5/0066 ,  A61B5/0073 ,  G02B26/105

Abstract: OCT imaging systems are provided for imaging a spherical-type eye including a source having an associated source arm path and a reference arm having an associated reference arm path coupled to the source path. The reference arm path has an associated reference arm path length. A sample is also provided having an associated sample arm path coupled to the source arm and reference arm paths. A lens having a focal power optimized for a diameter of the spherical-type eye is provided along with a reference arm path length adjustment module coupled to the reference arm. The reference arm path length adjustment module is configured to automatically adjust the reference arm path length such that the reference arm path length is based on an eye diameter of the subject.

公开(公告)号：US20170188817A1

公开(公告)日：2017-07-06

申请号：US15464568

申请日：2017-03-21

Applicant: Bioptigen, Inc.

Inventor： Robert H. Hart ,  Eric L. Buckland ,  Glenn A. Myers ,  Joseph A. Izatt ,  Joseph Elliott Vance

IPC: A61B3/10 ,  G02B26/10

CPC classification number: A61B3/102 ,  A61B5/0066 ,  A61B5/0073 ,  G02B26/105

Abstract: OCT imaging systems are provided for imaging a spherical-type eye including a source having an associated source arm path and a reference arm having an associated reference arm path coupled to the source path. The reference arm path has an associated reference arm path length. A sample is also provided having an associated sample arm path coupled to the source arm and reference arm paths. A lens having a focal power optimized for a diameter of the spherical-type eye is provided along with a reference arm path length adjustment module coupled to the reference arm. The reference arm path length adjustment module is configured to automatically adjust the reference arm path length such that the reference arm path length is based on an eye diameter of the subject.