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公开(公告)号:US10786605B2
公开(公告)日:2020-09-29
申请号:US15840815
申请日:2017-12-13
Applicant: Cardiac Pacemakers, Inc.
Inventor: Angelo Fruci , Arthur J. Foster , Joseph T. Delaney, Jr. , Danielle Frankson
IPC: A61L31/16 , A61N1/05 , A61N1/36 , A61L31/06 , A61N1/375 , A61N1/08 , A61N1/372 , B29C69/00 , B29K75/00 , B29K83/00 , B29K101/12 , B29L31/00
Abstract: An implantable medical electrical lead is connectable to an electrical header of an implantable pulse generator. The lead includes a lead body, at least one electrode, a lead terminal, and a lead boot. The lead body extends from a proximal end to a distal end. The at least one electrode is disposed at the distal end of the lead body. The lead terminal is disposed at the proximal end of the lead body and configured to connect the lead to the electrical header. The lead boot is formed of an elastic polymer infused with at least one antibiotic drug. A portion of the lead boot is configured to be disposed within the electrical header when the lead is connected to the electrical header.
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公开(公告)号:US10526429B2
公开(公告)日:2020-01-07
申请号:US15914409
申请日:2018-03-07
Applicant: Cardiac Pacemakers, Inc.
Inventor: Joseph T. Delaney, Jr. , Andrew J. Ro , Patrick Willoughby , Niraj Gurung
Abstract: A method for making a polyisobutylene diol from a polyisobutylene diallyl. The method includes hydroborating the polyisobutylene diallyl to produce a polyisobutylene dialkyl borane, and oxidizing the polyisobutylene dialkyl borane to form the polyisobutylene diol. The polyisobutylene diallyl is hydroborated by combining in situ the polyisobutylene diallyl with a borane-coordinating solvent, an alkaline metal salt of borohydride, and an acid. The alkaline metal salt of borohydride is combined with the polyisobutylene diallyl before the acid is combined with the polyisobutylene diallyl.
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公开(公告)号:US10342899B2
公开(公告)日:2019-07-09
申请号:US15382712
申请日:2016-12-18
Applicant: Cardiac Pacemakers, Inc.
Inventor: Joseph T. Delaney, Jr. , David R. Wulfman , Sarah M. Gruba , Michael J. Kane
IPC: A61L27/34 , A61L31/10 , C09D165/04
Abstract: A coating for an implantable medical device includes a poly(monochloro-p-xylylene) coating formed on at least a portion of the implantable medical device, and a layer including at least one of poly(ethylene glycol) and a poly(ethylene glycol) derivative linked to the poly(monochloro-p-xylylene) coating by covalent bonds.
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公开(公告)号:US10441688B2
公开(公告)日:2019-10-15
申请号:US15485491
申请日:2017-04-12
Applicant: Cardiac Pacemakers, Inc.
Inventor: Joseph T. Delaney, Jr. , David R. Wulfman , Adeniyi O. Aremu , Adegbola O. Adenusi
IPC: A61L31/10 , C09D7/20 , B05D1/04 , B05D3/04 , C08L67/02 , C09D167/02 , A61L27/34 , C08G63/183 , D01D1/02 , D01D5/00 , D01F6/62
Abstract: A method of making a solution including poly(ethylene terephthalate). The method includes dissolving poly(ethylene terephthalate) in a solvent mixture to form a solution, the solvent mixture including two solvent components. A Hansen Solubility Parameter Distance between the solvent mixture and HSP coordinates having a dispersion HSP of 18.02 MPa0.5, a polar HSP of 5.56 MPa0.5, and a hydrogen bonding HSP of 14.27 MPa0.5 is less than about 2 MPa0.5.
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公开(公告)号:US09987478B2
公开(公告)日:2018-06-05
申请号:US14600611
申请日:2015-01-20
Applicant: Cardiac Pacemakers, Inc.
Inventor: Adegbola O. Adenusi , James P. Rohl , David R. Wulfman , Joseph T. Delaney, Jr. , Adeniyi Aremu
IPC: B29C71/02 , A61M39/08 , A61M39/00 , B32B1/08 , B32B5/02 , B32B27/08 , B32B27/12 , D01D5/00 , D01D5/098 , A61L29/04 , A61L29/06 , A61L29/08 , A61L29/14 , A61L31/04 , A61L31/06 , A61L31/10 , A61L31/14 , A61N1/05
CPC classification number: A61M39/08 , A61L29/041 , A61L29/06 , A61L29/085 , A61L29/145 , A61L29/146 , A61L31/048 , A61L31/06 , A61L31/10 , A61L31/145 , A61L31/146 , A61M39/00 , A61N1/0541 , A61N1/056 , B32B1/08 , B32B5/02 , B32B5/022 , B32B27/08 , B32B27/12 , B32B2262/0238 , B32B2535/00 , D01D5/0023 , D01D5/0076 , D01D5/0084 , D01D5/0985 , Y10T428/1372 , C08L71/02 , C08L39/06 , C08L75/04 , C08L83/04
Abstract: A method for making a tubular medical device having a hybrid polymeric structure includes forming a first layer comprising a non-woven fibrous matrix made of a first polymeric material and forming a second layer comprising a second polymeric material about the first layer such that at least a portion of the second polymeric material of the second layer embeds into at least a portion of the first polymeric material of the first layer.
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公开(公告)号:US09415206B2
公开(公告)日:2016-08-16
申请号:US14825166
申请日:2015-08-12
Applicant: Cardiac Pacemakers, Inc.
Inventor: Devon N. Arnholt , Douglas D. Pagoria , Jeannette C. Polkinghorne , Joseph T. Delaney, Jr.
CPC classification number: A61N1/05 , A61N1/056 , D01D5/0023 , D01D5/0084 , D10B2321/08 , D10B2331/06 , Y10T29/4922 , Y10T29/49224
Abstract: A medical electrical lead may include an insulative lead body, a conductor disposed within the insulative lead body, an electrode disposed on the insulative lead body and in electrical contact with the conductor and a fibrous matrix disposed at least partially over the electrode. The fibrous matrix may be formed from polyether polyurethane.
Abstract translation: 医疗电引线可以包括绝缘引线体,布置在绝缘引线体内的导体,设置在绝缘引线体上并与导体电接触的电极和至少部分地布置在电极上的纤维基质。 纤维基质可以由聚醚聚氨酯形成。
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公开(公告)号:US09132269B2
公开(公告)日:2015-09-15
申请号:US14556818
申请日:2014-12-01
Applicant: Cardiac Pacemakers, Inc.
Inventor: Devon N. Arnholt , Douglas D. Pagoria , Jeannette C. Polkinghorne , Joseph T. Delaney, Jr.
CPC classification number: A61N1/05 , A61N1/056 , D01D5/0023 , D01D5/0084 , D10B2321/08 , D10B2331/06 , Y10T29/4922 , Y10T29/49224
Abstract: A medical electrical lead may include an insulative lead body, a conductor disposed within the insulative lead body, an electrode disposed on the insulative lead body and in electrical contact with the conductor and a fibrous matrix disposed at least partially over the electrode. The fibrous matrix may be formed from polytetrafluoroethylene.
Abstract translation: 医疗电引线可以包括绝缘引线体,布置在绝缘引线体内的导体,设置在绝缘引线体上并与导体电接触的电极和至少部分地布置在电极上的纤维基质。 纤维基质可以由聚四氟乙烯形成。
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公开(公告)号:US11491338B2
公开(公告)日:2022-11-08
申请号:US16206826
申请日:2018-11-30
Applicant: Cardiac Pacemakers, Inc.
Inventor: Michael J. Kane , Joseph T. Delaney, Jr. , Kasyap Seethamraju
Abstract: A method of making a feed-thru connector assembly includes inserting a conductor within an opening within a housing of a pulse generator and dispensing a sealant in a gap between the conductor and portions of the housing adjacent to the conductor that define the opening of the housing and curing the sealant to form a seal comprising a polyisobutylene cross-linked network.
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公开(公告)号:US11185615B2
公开(公告)日:2021-11-30
申请号:US16598402
申请日:2019-10-10
Applicant: Cardiac Pacemakers, Inc.
Inventor: Joseph T. Delaney, Jr. , David R. Wulfman , Adeniyi O. Aremu , Adegbola O. Adenusi
IPC: A61L31/10 , D01D1/02 , C08G63/183 , A61L27/34 , D01D5/00 , D01F6/62 , C09D7/20 , B05D1/04 , B05D3/04 , C08L67/02 , C09D167/02
Abstract: A method of making a solution including poly(ethylene terephthalate). The method includes dissolving poly(ethylene terephthalate) in a solvent mixture to form a solution, the solvent mixture including two solvent components. A Hansen Solubility Parameter Distance between the solvent mixture and HSP coordinates having a dispersion HSP of 18.02 MPa0.5, a polar HSP of 5.56 MPa0.5, and a hydrogen bonding HSP of 14.27 MPa0.5 is less than about 2 MPa0.5.
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公开(公告)号:US10517999B2
公开(公告)日:2019-12-31
申请号:US15485390
申请日:2017-04-12
Applicant: Cardiac Pacemakers, Inc.
Inventor: John Kummailil , Paul V. Grosso , Joseph T. Delaney, Jr.
IPC: A61L29/06 , A61L29/08 , A61L29/14 , A61L31/10 , A61L31/14 , B05D1/00 , B05D1/02 , B05D1/18 , C08J7/04 , C09D139/06
Abstract: A medical device for insertion or implantation in a body includes a polymer substrate and a layer of poly(vinyl pyrrolidone-alt-maleic anhydride) formed on a surface of the polymer substrate. Polymer chains of the poly(vinyl pyrrolidone-alt-maleic anhydride) are entangled with the polymer substrate.
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