公开(公告)号：US20130115466A1

公开(公告)日：2013-05-09

申请号：US13723679

申请日：2012-12-21

Applicant: Coloplast A/S

Inventor： Niels Jorgen Madsen ,  Egon Triel ,  Bo Rud Nielsen ,  Carsten Hoj

IPC: B05D5/08

CPC classification number: B05D3/067 ,  A61L27/34 ,  A61L29/085 ,  A61L31/10 ,  A61L31/14 ,  B05D5/08 ,  B05D2201/00 ,  B29C45/0053 ,  B29C45/14 ,  B29C45/1679 ,  B29C47/0023 ,  B29C47/021 ,  B29C71/04 ,  B29C2035/0827 ,  B29C2045/0075 ,  B29K2023/06 ,  B29K2023/083 ,  B29K2023/086 ,  B29K2075/00 ,  B29K2077/00 ,  B29K2995/0092 ,  B29L2031/753 ,  B29L2031/7542 ,  C08G18/4833 ,  C08G18/83 ,  C08G65/331 ,  C08G65/3324 ,  C08G2210/00 ,  Y10T428/31511 ,  Y10T428/31551 ,  Y10T428/31786

Abstract: The present invention relates to a method for the preparation of a medical device element by means of extrusion or injection moulding and to medical devices comprising such extruded or injection moulded medical device elements. The medical device elements (e.g. tubes, wires, lines, stents, catheters, guides, endodontic instruments, needles, trocars for e.g. laparoscopic surgery, laparoscopic accessories, surgical instruments, guide wires) are characterized by a prefabricated shaped article or a thermoplastic substrate polymer having thereon a layer of a covalently cross-linked coating composition of a thermoplastic matrix polymer and a hydrophilic polymer. The method involves a coating composition comprising a thermoplastic matrix polymer, a hydrophilic polymer, and one or more photo-initiator(s), e.g. covalently linked to molecules of the thermoplastic matrix polymer and/or to molecules of the hydrophilic polymer. The coating composition is irradiated with UV or visible light so as to covalently cross-link said coating composition.

Abstract translation: 本发明涉及一种通过挤出或注射成型制备医疗器械元件的方法以及包括这种挤出或注塑的医疗器械元件的医疗装置。 医疗器械元件（例如管，线，线，支架，导管，导管，根管器械，针，例如腹腔镜手术的套管针，腹腔镜附件，手术器械，导丝）的特征在于预制成形制品或热塑性基底聚合物 在其上具有一层共价交联的热塑性基质聚合物和亲水性聚合物的涂料组合物。 该方法涉及包含热塑性基质聚合物，亲水性聚合物和一种或多种光引发剂的涂料组合物，例如， 与热塑性基质聚合物的分子和/或亲水性聚合物的分子共价连接。 用UV或可见光照射涂料组合物以共价交联所述涂料组合物。

公开(公告)号：US10252291B2

公开(公告)日：2019-04-09

申请号：US13723679

申请日：2012-12-21

Applicant: Coloplast A/S

Inventor： Niels Jorgen Madsen ,  Egon Triel ,  Bo Rud Nielsen ,  Carsten Hoj

IPC: B05D5/08 ,  B05D3/06 ,  A61L27/34 ,  A61L29/08 ,  A61L31/10 ,  B29C45/00 ,  B29C45/14 ,  B29C45/16 ,  B29C47/00 ,  B29C47/02 ,  C08G18/48 ,  C08G18/83 ,  C08G65/331 ,  C08G65/332 ,  A61L31/14 ,  B29C71/04 ,  B29C35/08 ,  B29K23/00 ,  B29K75/00 ,  B29K77/00 ,  B29L31/00

Abstract: The present invention relates to a method for the preparation of a medical device element by means of extrusion or injection molding and to medical devices comprising such extruded or injection molded medical device elements. The medical device elements (e.g. tubes, wires, lines, stents, catheters, guides, endodontic instruments, needles, trocars for e.g. laparoscopic surgery, laparoscopic accessories, surgical instruments, guide wires) are characterized by a prefabricated shaped article or a thermoplastic substrate polymer having thereon a layer of a covalently cross-linked coating composition of a thermoplastic matrix polymer and a hydrophilic polymer. The method involves a coating composition comprising a thermoplastic matrix polymer, a hydrophilic polymer, and one or more photo-initiator(s), e.g. covalently linked to molecules of the thermoplastic matrix polymer and/or to molecules of the hydrophilic polymer. The coating composition is irradiated with UV or visible light so as to covalently cross-link said coating composition.