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公开(公告)号：US09440482B2
公开(公告)日：2016-09-13
申请号：US14329370
申请日：2014-07-11
Applicant: David Cunningham
Inventor： David Cunningham
CPC classification number: B43L13/149 , B43L13/148
Abstract: A drawing tool is provided for assisting artists in transcribing images onto a blank medium. The device is a drawing frame of geometrical shape and has a plurality of notches disposed along the outer perimeter length. These notches are channels cut out of the edge, forming protruding segments between any two notches. Protruding segments are used as anchor sites for a series of elastic threads. A portion of the threads is wound around protruding segments disposed on opposing dies of the frame body, thereby stretching the elastic thread across the front surface of the frame body. A first grouping of the threads is secured in parallel lateral alignment, while a second group is secured in a parallel longitudinal alignment. This configuration presents a grid pattern that can be laid over an image or blank piece of paper to serve as a guide for transcription.
Abstract translation: 提供绘图工具来帮助艺术家将图像转录到空白介质上。 该装置是几何形状的绘图框架，并且具有沿着外周长设置的多个凹口。 这些凹口是从边缘切出的通道，在任何两个凹口之间形成突出的段。 突出部分用作一系列弹性线的锚点。 螺纹的一部分缠绕在设置在框体的相对的模具上的突出部分上，从而将弹性线拉伸穿过框体的前表面。 螺纹的第一组分以平行的横向对准固定，而第二组以平行的纵向对准固定。 该配置呈现可以放置在图像或空白纸上以用作转录指南的网格图案。
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公开(公告)号：US20070099526A1
公开(公告)日：2007-05-03
申请号：US11545115
申请日：2006-10-05
Applicant: Jason Heerden , Shekoufeh Shahkarami , David Cunningham , Laura Pritchard
Inventor： Jason Heerden , Shekoufeh Shahkarami , David Cunningham , Laura Pritchard
CPC classification number: D03D15/02 , D03D1/0052 , D03D15/0016 , D03D25/005 , D04B21/16 , D10B2331/021 , D10B2401/063 , F41H5/0485 , Y10S428/911 , Y10T428/24058 , Y10T428/24132 , Y10T428/24174 , Y10T442/2615 , Y10T442/2623 , Y10T442/2762 , Y10T442/2861 , Y10T442/2992
Abstract: A fabric including a first layer of high-performance unidirectional yarns and a second layer of high-performance unidirectional yarns disposed transversely to the first layer. The fabric also includes warp and fill encapsulating yarns woven around the unidirectional yarns to substantially stabilize the unidirectional yarns. The encapsulating yarns have tenacities and tensile moduli substantially less than the tenacities and tensile moduli of the unidirectional yarns. The fabric has a cover factor between approximately 0.75 and approximately 1.50.
Abstract translation: 包括第一层高性能单向纱线和横向于第一层布置的第二层高性能单向纱线的织物。 织物还包括围绕单向纱线编织的经纱和填充包封纱，以基本上稳定单向纱线。 封装纱线具有显着小于单向纱线的强度和拉伸模量的强度和拉伸模量。 织物的覆盖系数在约0.75至约1.50之间。
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公开(公告)号：US20140098001A1
公开(公告)日：2014-04-10
申请号：US14001554
申请日：2012-03-05
Applicant: Eelco van Oosterbosch , Reimo Nickel , Chae Thompson , David Cunningham
Inventor： Eelco van Oosterbosch , Reimo Nickel , Chae Thompson , David Cunningham
IPC: H01Q1/42
Abstract: The invention relates to a geodesic radome comprising shaped panels containing a consolidated plurality of plies, the plies comprising polyolefin tapes, wherein the shaped panels have a compressive strength of between 10 MPa and 100 MPa, an interlaminar shear strength of between 3 MPa and 75 MPa and a thermal expansion of between 1e−6 1/K and 50e−6 1/K.
Abstract translation: 本发明涉及一种测地雷达罩，其包括含有固结的多个层的成形板，该层包含聚烯烃带，其中成形板的抗压强度为10MPa至100MPa，层间剪切强度为3MPa至75MPa 和1e-6l / K和50e-6l / K之间的热膨胀。
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公开(公告)号：US20120296189A1
公开(公告)日：2012-11-22
申请号：US13458556
申请日：2012-04-27
Applicant: John Bhogal , Shridhara Alva Karinka , Timothy P. Henning , David Cunningham , Udo Hoss , Andrew H. Naegeli , John LaTour
Inventor： John Bhogal , Shridhara Alva Karinka , Timothy P. Henning , David Cunningham , Udo Hoss , Andrew H. Naegeli , John LaTour
CPC classification number: A61B10/0045 , A61B5/14503 , A61B5/14514 , A61B5/14532 , A61B5/1459 , A61B5/1495 , A61B2010/008 , G01N30/96
Abstract: Provided are methods of measuring analyte concentrations in interstitial fluid samples, methods of determining accuracy of subcutaneously implantable analyte sensors, methods of manufacturing and determining calibration factors for subcutaneously implantable analyte sensors, as well as subcutaneously implantable analyte sensors manufactured according to the described methods and having a high level of accuracy. Methods of determining the concentration of an analyte in a bodily sample, and methods of extracting interstitial fluid are also provided.
Abstract translation: 提供了测量间质液样品中分析物浓度的方法，确定皮下可植入分析物传感器的准确性的方法，制备和确定皮下可植入分析物传感器的校准因子的方法，以及根据所述方法制造的皮下可植入分析物传感器，并具有 高精度。 还提供了确定身体样品中分析物浓度的方法和提取组织液的方法。
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公开(公告)号：US6077236A
公开(公告)日：2000-06-20
申请号：US750842
申请日：1996-12-05
Applicant: David Cunningham
Inventor： David Cunningham
CPC classification number: A61N1/37211 , A61B5/0031 , A61B5/4839 , A61B5/6882 , A61N1/36542
Abstract: Apparatus for monitoring cardiac contractility comprises a catheter having a tip for insertion into the ventricle of the heart muscle. At or proximate the tip is an acceleration transducer responsive to the natural, multi-directional heart acceleration to provide an acceleration signal to a signal processor. The apparatus is arranged to suppress frequencies outside the range approximately 15 Hz to approximately 100 Hz.
Abstract translation: PCT No.PCT / GB95 / 01326 Sec。 371日期：1996年12月5日 102（e）日期1996年12月5日PCT提交1994年6月7日PCT公布。 公开号WO95 / 33517 日期1995年12月14日用于监测心脏收缩力的装置包括具有插入心肌心室的尖端的导管。 尖端处或附近是响应于自然多方向心脏加速度的加速度换能器，以向信号处理器提供加速度信号。 该装置被设置为抑制在大约15Hz至大约100Hz的范围之外的频率。
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Patent Agency Ranking
公开(公告)号：US09397392B2
公开(公告)日：2016-07-19
申请号：US14001554
申请日：2012-03-05
Applicant: Eelco van Oosterbosch , Reimo Nickel , Chae Thompson , David Cunningham
Inventor： Eelco van Oosterbosch , Reimo Nickel , Chae Thompson , David Cunningham
Abstract: The invention relates to a geodesic radome comprising shaped panels containing a consolidated plurality of plies, the plies comprising polyolefin tapes, wherein the shaped panels have a compressive strength of between 10 MPa and 100 MPa, an interlaminar shear strength of between 3 MPa and 75 MPa and a thermal expansion of between 1e−6 1/K and 50e−6 1/K.
Abstract translation: 本发明涉及一种测地雷达罩，其包括含有固结的多个层的成形板，该层包含聚烯烃带，其中成形板的抗压强度为10MPa至100MPa，层间剪切强度为3MPa至75MPa 和1e-6l / K和50e-6l / K之间的热膨胀。
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7.发明申请公开(公告)号：US20140059552A1
公开(公告)日：2014-02-27
申请号：US13593718
申请日：2012-08-24
Applicant: David Cunningham , Benjamin W. Herta , Vijay A. Saraswat , Avraham E. Shinnar
Inventor： David Cunningham , Benjamin W. Herta , Vijay A. Saraswat , Avraham E. Shinnar
IPC: G06F9/46
CPC classification number: G09G5/00 , G06F16/00 , G06F16/2471
Abstract: Executing a map reduce sequence may comprise executing all jobs in the sequence by a collection of a plurality of processes with each process running zero or more mappers, combiners, partitioners and reducers for each job, and transparently sharing heap state between the jobs to improve metrics associated with the job. Processes may communicate among themselves to coordinate completion of map, shuffle and reduce phases, and completion of said all jobs in the sequence.
Abstract translation: 执行地图缩减序列可以包括通过多个进程的集合执行序列中的所有作业，每个进程为每个作业运行零个或多个映射器，组合器，分区器和缩减器，并且在作业之间透明地共享堆状态以改善度量 与工作有关。 过程可以在它们之间进行通信，以协调地图的完成，洗牌和减少阶段，以及完成所述序列中的所有作业。
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8.发明申请Method and system for dispensing, tracking and managing pharmaceutical products 有权配药，跟踪和管理药品的方法和系统.uss公开(公告)号：US20050033610A1
公开(公告)日：2005-02-10
申请号：US10922302
申请日：2004-08-19
Applicant: David Cunningham
Inventor： David Cunningham
Abstract: A new and improved method of dispensing, tracking and managing pharmaceutical product samples by communicatively linking prescribers and pharmacies to a central computing station. The present invention entails utilizing product trial media that is exchanged for actual pharmaceutical product. The media is encoded with information that identifies a particular pharmaceutical trial product, such as by magnetic encoding similar to that used with credit cards. The media is distributed to participating medical doctors or prescribers who then activate the media via the central computing station. The prescriber then transfers the activated media to patients who then present the media to participating pharmacies. Before filling the pharmaceutical trial product identified by the media, the pharmacy validates the media via a link with the central computing station. Then, the pharmacy dispenses the prescribed pharmaceutical trial product. The central computing station also includes a database that records data related to the use of the media so that all pharmaceutical trial products can be accounted for.
Abstract translation: 一种新的和改进的方法，通过将处方药和药房通信地连接到中央计算站来分配，跟踪和管理药品样品。 本发明需要使用与实际药品交换的产品试验介质。 媒体用识别特定药物试验产品的信息进行编码，例如通过与用于信用卡的磁编码类似的磁编码。 媒体分发给参与的医生或处方者，然后通过中央计算站激活媒体。 然后，处方者将活化的媒介转移给随后向参与药房提供媒体的患者。 在填写由媒体确定的药学试用产品之前，药房通过与中央计算站的链接来验证媒体。 然后，药店分配处方药试剂。 中央计算站还包括一个数据库，记录与媒体的使用相关的数据，以便所有的药物试验产品都可以被考虑。
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9.发明授权
公开(公告)号：US5593959A
公开(公告)日：1997-01-14
申请号：US135929
申请日：1993-10-14
Applicant: Jonathan L. Miller , David Cunningham , Vicki A. Lyle , Clara N. Finch , Matthew R. Pincus
Inventor： Jonathan L. Miller , David Cunningham , Vicki A. Lyle , Clara N. Finch , Matthew R. Pincus
IPC: A61K38/00 , A61K47/48 , C07K14/705 , C12N15/12 , C07K14/745 , A61K38/17 , A61K38/36
CPC classification number: A61K47/48238 , C07K14/705 , A61K38/00
Abstract: The subject invention provides purified polypeptides encoded by naturally-occurring wild-type platelet glycoprotein Ib alpha having a mutation which renders the polypeptide more reactive with von Willebrand factor. Preferably, the mutation is in the hinge region of GP Ib.alpha., such as the substitution of valine for glycine at residue 233. These mutations alter the three-dimensional structure of the mutant polypeptide from a beta bend conformation to an alpha helix formation, and also create an amphipathic region within the mutant polypeptide. DNA encoding the mutant polypeptides, as well as expression systems for the production of the mutant polypeptides, are also provided. Methods and compositions using the mutant polypeptides and DNA oligomers complementary to the mutant polypeptides are further provided.
Abstract translation: 本发明提供由天然存在的野生型血小板糖蛋白Ibα编码的纯化多肽，其具有使得多肽与血管性血友病因子更具反应性的突变。 优选地，突变位于GPIbα的铰链区，例如在残基233处取代缬氨酸甘氨酸。这些突变将突变多肽的三维结构从β弯曲构象改变为α螺旋形成，并且 还在突变体多肽内产生两亲性区域。 还提供了编码突变体多肽的DNA，以及用于产生突变体多肽的表达系统。 还提供了使用与突变体多肽互补的突变多肽和DNA寡聚体的方法和组合物。
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公开(公告)号：US20150013176A1
公开(公告)日：2015-01-15
申请号：US14329370
申请日：2014-07-11
Applicant: David Cunningham
Inventor： David Cunningham
IPC: B43L13/02
CPC classification number: B43L13/149 , B43L13/148
Abstract: A drawing tool is provided for assisting artists in transcribing images onto a blank medium. The device is a drawing frame of geometrical shape and has a plurality of notches disposed along the outer perimeter length. These notches are channels cut out of the edge, forming protruding segments between any two notches. Protruding segments are used as anchor sites for a series of elastic threads. A portion of the threads is wound around protruding segments disposed on opposing dies of the frame body, thereby stretching the elastic thread across the front surface of the frame body. A first grouping of the threads is secured in parallel lateral alignment, while a second group is secured in a parallel longitudinal alignment. This configuration presents a grid pattern that can be laid over an image or blank piece of paper to serve as a guide for transcription.
Abstract translation: 提供绘图工具来帮助艺术家将图像转录到空白介质上。 该装置是几何形状的绘图框架，并且具有沿着外周长设置的多个凹口。 这些凹口是从边缘切出的通道，在任何两个凹口之间形成突出的段。 突出部分用作一系列弹性线的锚点。 螺纹的一部分缠绕在设置在框体的相对的模具上的突出部分上，从而将弹性线拉伸穿过框体的前表面。 螺纹的第一组分以平行的横向对准固定，而第二组以平行的纵向对准固定。 该配置呈现可以放置在图像或空白纸上以用作转录指南的网格图案。
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