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公开(公告)号:US20190054203A1
公开(公告)日:2019-02-21
申请号:US16169045
申请日:2018-10-24
Applicant: Omrix Biopharmaceuticals Ltd. , Ethicon, Inc.
Inventor: Erez ILAN , Omri Faingold , Nataly Freizus , Ronen Eavri , Dwayne Looney , Sridevi Dhanaraj , James Galloway , Walter Danker
Abstract: The invention relates to a hemostatic composition comprising a mixture of cellulose-based short and long fibers, preparation and use thereof.
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公开(公告)号:US11986489B2
公开(公告)日:2024-05-21
申请号:US17167428
申请日:2021-02-04
Applicant: Ethicon, Inc. , Omrix Biopharmaceuticals Ltd.
Inventor: James Galloway , Tamara Byk-Tennenbaum , Erez Ilan , Lior Weissman , Sivan Doron , Eve Montia
IPC: A61K31/717 , A61K31/704 , A61L15/28 , A61L15/44 , A61L24/00 , A61L24/08
CPC classification number: A61K31/717 , A61K31/704 , A61L15/28 , A61L15/44 , A61L24/0015 , A61L24/0042 , A61L24/08 , A61L2400/04 , A61K31/704 , A61K2300/00 , A61L15/28 , C08L1/04 , A61L24/08 , C08L1/04 , A61K31/717 , A61K2300/00
Abstract: The present invention is directed to methods of enhancing toxicity of a glycolytic dependent compound towards a cancerous tissue and/or organ in a subject, the method being comprised of targeting the glycolytic dependent compound to the cancerous tissue and/or organ by placing oxidized regenerated cellulose (ORC) and/or oxidized cellulose (OC) in direct connection with the cancerous tissue and/or organ, and administering the glycolytic dependent compound to the subject by a systemic route.
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公开(公告)号:US11007300B2
公开(公告)日:2021-05-18
申请号:US16167924
申请日:2018-10-23
Applicant: Omrix Biopharmaceuticals Ltd. , Ethicon, Inc.
Inventor: Erez Ilan , Omri Faingold , Nataly Freizus , Ronen Eavri , Dwayne Looney , Sridevi Dhanaraj , James Galloway , Walter Danker
Abstract: The present invention relates to improved hemostatic compositions comprising cellulose-based fibers supplemented with compounds, preparation and use thereof.
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公开(公告)号:US10137221B2
公开(公告)日:2018-11-27
申请号:US15346236
申请日:2016-11-08
Applicant: Omrix Biopharmaceuticals Ltd. , Ethicon, Inc.
Inventor: Erez Ilan , Omri Faingold , Nataly Freizus , Ronen Eavri , Dwayne Looney , Sridevi Dhanaraj , James Galloway , Walter Danker
Abstract: The invention relates to a hemostatic composition comprising a mixture of cellulose-based short and long fibers, preparation and use thereof.
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公开(公告)号:US10960105B2
公开(公告)日:2021-03-30
申请号:US16783403
申请日:2020-02-06
Applicant: Omrix Biopharmaceuticals Ltd. , Ethicon, Inc.
Inventor: Erez Ilan , Omri Faingold , Nataly Freizus , Ronen Eavri , Dwayne Looney , Sridevi Dhanaraj , James Galloway , Walter Danker
Abstract: The present invention relates to improved hemostatic compositions comprising cellulose-based fibers supplemented with compounds, preparation and use thereof.
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公开(公告)号:US10960021B2
公开(公告)日:2021-03-30
申请号:US15234177
申请日:2016-08-11
Applicant: Ethicon, Inc. , Omrix Biopharmaceuticals Ltd.
Inventor: James Galloway , Tamara Byk-Tennenbaum , Erez Ilan , Lior Weissman , Sivan Doron , Eve Montia
IPC: A61F2/00 , A61K31/717 , A61K31/704 , A61L24/00 , A61L15/28 , A61L24/08 , A61L15/44
Abstract: Provided is a method of enhancing toxicity of a glycolytic dependent compound towards a cell, tissue and/or organ e.g. a diseased cell, tissue and/or organ, the method comprises contacting Oxidized Regenerated Cellulose (ORC) and/or Oxidized Cellulose (OC); and a glycolytic dependent compound with the cell, tissue and/or organ. The ORC and/or OC; and the glycolytic dependent compound are contacted with the cell, tissue and/or organ in a non-blended form.
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公开(公告)号:US20200171201A1
公开(公告)日:2020-06-04
申请号:US16783403
申请日:2020-02-06
Applicant: Omrix Biopharmaceuticals Ltd. , Ethicon, Inc.
Inventor: Erez ILAN , Omri Faingold , Nataly Freizus , Ronen Eavri , Dwayne Looney , Sridevi Dhanaraj , James Galloway , Walter Danker
Abstract: The present invention relates to improved hemostatic compositions comprising cellulose-based fibers supplemented with compounds, preparation and use thereof.
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公开(公告)号:US20170128619A1
公开(公告)日:2017-05-11
申请号:US15346193
申请日:2016-11-08
Applicant: Omrix Biopharmaceuticals Ltd. , Ethicon, Inc.
Inventor: EREZ ILAN , Omri Faingold , Nataly Freizus , Ronen Eavri , Dwayne Looney , Sridevi Dhanaraj , James Galloway , Walter Danker
IPC: A61L26/00
CPC classification number: A61L26/0023 , A61L24/001 , A61L24/0015 , A61L24/02 , A61L24/043 , A61L24/06 , A61L24/08 , A61L26/00 , A61L26/0004 , A61L2300/106 , A61L2300/232 , A61L2300/25 , A61L2300/418 , A61L2300/802 , A61L2400/04 , C08L1/04
Abstract: The present invention relates to improved hemostatic compositions comprising cellulose-based fibers supplemented with compounds, preparation and use thereof.
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公开(公告)号:US11712495B2
公开(公告)日:2023-08-01
申请号:US17167492
申请日:2021-02-04
Applicant: Omrix Biopharmaceuticals Ltd. , Ethicon, Inc.
Inventor: Erez Ilan , Omri Faingold , Nataly Freizus , Ronen Eavri , Dwayne Looney , Sridevi Dhanaraj , James Galloway , Walter Danker
CPC classification number: A61L26/0023 , A61L24/001 , A61L24/0015 , A61L24/02 , A61L24/043 , A61L24/06 , A61L24/08 , A61L26/00 , A61L26/0004 , A61L2300/106 , A61L2300/232 , A61L2300/25 , A61L2300/418 , A61L2300/802 , A61L2400/04 , A61L24/043 , C08L1/04 , A61L24/06 , C08L1/04
Abstract: The invention relates to a hemostatic composition comprising a mixture of cellulose-based short and long fibers, preparation and use thereof.
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公开(公告)号:US20210154224A1
公开(公告)日:2021-05-27
申请号:US17167428
申请日:2021-02-04
Applicant: Ethicon, Inc. , Omrix Biopharmaceuticals Ltd.
Inventor: James Galloway , Tamara BYK-TENNENBAUM , Erez ILAN , Lior WEISSMAN , Sivan DORON , Eve MONTIA
IPC: A61K31/717 , A61K31/704 , A61L24/00 , A61L15/28 , A61L24/08 , A61L15/44
Abstract: Provided is a method of enhancing toxicity of a glycolytic dependent compound towards a cell, tissue and/or organ e.g. a diseased cell, tissue and/or organ, the method comprises contacting Oxidized Regenerated Cellulose (ORC) and/or Oxidized Cellulose (OC); and a glycolytic dependent compound with the cell, tissue and/or organ. The ORC and/or OC; and the glycolytic dependent compound are contacted with the cell, tissue and/or organ in a non-blended form.
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