公开(公告)号：US10094783B2

公开(公告)日：2018-10-09

申请号：US15215211

申请日：2016-07-20

Applicant: FUNDAMENTAL SOLUTIONS CORPORATION

Inventor： Marvin R. Williams ,  Charles McBrairty ,  Daniel W. Pfautz ,  Thomas J. Zupancic ,  Lingchun Zeng ,  Andrew Weiman ,  Richard S. Brody ,  Joseph D. Kittle ,  Anthony Truscott ,  Robert Baranowski

IPC: C12M1/00 ,  B01L3/00 ,  G01N21/76 ,  G01N33/02 ,  G01N33/569 ,  G01N33/536

Abstract: A system for use in rapid sample analysis that includes a biosensor reagent, wherein the biosensor reagent includes living biological cells; a reservoir card, wherein the reservoir card stores the biosensor reagent; and a test cartridge base, wherein the test cartridge base is configured to accept the reservoir card, and wherein the test cartridge base further includes a reaction chamber having a central axis, wherein the reaction chamber has the shape of a revolved half ellipse; and an inlet channel connected to the reaction chamber, wherein the inlet channel is positioned above the reaction chamber at an angle of 15-60 degrees above the horizontal, and wherein the inlet channel is offset from the central axis of the reaction chamber.

公开(公告)号：USD806890S1

公开(公告)日：2018-01-02

申请号：US29533687

申请日：2015-07-21

Applicant: FUNDAMENTAL SOLUTIONS CORPORATION

Designer： Marvin R. Williams ,  Charles McBrairty ,  Daniel W. Pfautz ,  Andrew Weiman

公开(公告)号：US09701995B2

公开(公告)日：2017-07-11

申请号：US14670007

申请日：2015-03-26

Applicant: FUNDAMENTAL SOLUTIONS CORPORATION

Inventor： Marvin R. Williams ,  Charles McBrairty ,  Daniel W. Pfautz ,  Thomas J. Zupancic ,  Lingchun Zeng ,  Andrew Weiman ,  Richard S. Brody ,  Joseph D. Kittle ,  Anthony Truscott ,  Robert Baranowski

IPC: C12M1/00 ,  C12M3/00 ,  B01L3/00 ,  C12Q1/10 ,  G01N21/75 ,  G01N21/76 ,  G01N33/12 ,  G01N33/569

CPC classification number: C12Q1/10 ,  G01N21/75 ,  G01N21/763 ,  G01N33/12 ,  G01N33/56916 ,  G01N2201/0221

Abstract: A test cartridge for use in sample analysis is provided. The test cartridge includes a reservoir card that further includes a reagent that includes living biological cells; and a test cartridge base configured to accept the reservoir card. The reservoir card is configured to interface with a test cartridge base through at least one fluid port. The test cartridge base includes an elliptical reaction chamber having a central axis and an inlet channel connected to the reaction chamber. The inlet channel is positioned above the reaction chamber at an angle of 15-60 degrees above the horizontal and is offset from the central axis of the reaction chamber. Upon introducing a sample to be analyzed into the test cartridge base through the inlet channel, the sample is homogeneously mixed with the reagent while minimizing damage to the living biological cells.

公开(公告)号：US10241054B2

公开(公告)日：2019-03-26

申请号：US15214175

申请日：2016-07-19

Applicant: FUNDAMENTAL SOLUTIONS CORPORATION

Inventor： Marvin R. Williams ,  Charles McBrairty ,  Daniel W. Pfautz ,  Thomas J. Zupancic ,  Lingchun Zeng ,  Andrew Weiman ,  Richard S. Brody ,  Joseph D. Kittle ,  Anthony Truscott ,  Robert Baranowski

IPC: B01L3/00 ,  G01N21/00 ,  G01N21/76 ,  G01N33/02 ,  G01N33/569 ,  C12Q1/10

Abstract: A system for use in rapid sample analysis that includes a biosensor reagent, wherein the biosensor reagent includes living biological cells; a reservoir card, wherein the reservoir card stores the biosensor reagent; and a test cartridge base, wherein the test cartridge base is configured to accept the reservoir card, and wherein the test cartridge base further includes a contoured reaction chamber; and an inlet channel connected to and entering the reaction chamber at a predetermined angle thereto.

公开(公告)号：USD807213S1

公开(公告)日：2018-01-09

申请号：US29597323

申请日：2017-03-16

Applicant: FUNDAMENTAL SOLUTIONS CORPORATION

Designer： Marvin R. Williams ,  Charles McBrairty ,  Daniel W. Pfautz ,  Andrew Weiman ,  Edward Mitchell

CPC classification number: C12Q1/10 ,  G01N21/75 ,  G01N21/763 ,  G01N33/12 ,  G01N33/56916 ,  G01N2201/0221

Abstract: A portable system for real time detection of the presence of an infectious agent in a biological sample employs a reagent which detects the presence of a specific infectious agent in the sample, and emits a detectable signal when the reagent reacts with the sample and detects the presence of the infectious agent. A test cartridge has a reaction chamber for receiving the sample and the reagent. The reaction chamber has a predetermined internal geometry and at least one inner surface. Introducing the sample and the reagent into the test cartridge mixes the sample and the reagent. A testing unit receives the test cartridge, and includes a sensor for detecting an emitted detectable signal. The detection of the emitted detectable signal is indicative of the presence of the infectious agent in the sample.

公开(公告)号：USD846145S1

公开(公告)日：2019-04-16

申请号：US29632418

申请日：2018-01-08

Applicant: FUNDAMENTAL SOLUTIONS CORPORATION

Designer： Marvin R. Williams ,  Charles McBrairty ,  Daniel W. Pfautz ,  Andrew Weiman

公开(公告)号：US09701994B2

公开(公告)日：2017-07-11

申请号：US14669970

申请日：2015-03-26

Applicant: FUNDAMENTAL SOLUTIONS CORPORATION

Inventor： Marvin R. Williams ,  Charles McBrairty ,  Daniel W. Pfautz ,  Thomas J. Zupancic ,  Lingchun Zeng ,  Andrew Weiman ,  Richard S. Brody ,  Joseph D. Kittle ,  Anthony Truscott ,  Robert Baranowski

IPC: G01N33/00 ,  C12Q1/70 ,  C12Q1/10 ,  G01N21/75 ,  G01N21/76 ,  G01N33/12 ,  G01N33/569

CPC classification number: C12Q1/10 ,  G01N21/75 ,  G01N21/763 ,  G01N33/12 ,  G01N33/56916 ,  G01N2201/0221

Abstract: A system for use in rapid sample analysis that includes a biosensor reagent, wherein the biosensor reagent includes living biological cells; a reservoir card, wherein the reservoir card stores the biosensor reagent; and a test cartridge base, wherein the test cartridge base is configured to accept the reservoir card, and wherein the test cartridge base further includes a reaction chamber having a central axis, wherein the reaction chamber has the shape of a revolved half ellipse; and an inlet channel connected to the reaction chamber, wherein the inlet channel is positioned above the reaction chamber at an angle of 15-60 degrees above the horizontal, and wherein the inlet channel is offset from the central axis of the reaction chamber.

公开(公告)号：US09023640B2

公开(公告)日：2015-05-05

申请号：US13711296

申请日：2012-12-11

Applicant: Fundamental Solutions Corporation

Inventor： Marvin R. Williams ,  Charles McBrairty ,  Daniel W. Pfautz ,  Thomas J. Zupancic ,  Lingchun Zeng ,  Andrew Weiman ,  Richard S. Brody ,  Joseph Kittle ,  Anthony Truscott ,  Robert Baranowski

IPC: C12M1/00 ,  C12M3/00 ,  G01N21/75 ,  G01N21/76 ,  G01N33/12

CPC classification number: C12Q1/10 ,  G01N21/75 ,  G01N21/763 ,  G01N33/12 ,  G01N33/56916 ,  G01N2201/0221

Abstract: A portable system for real time detection of the presence of an infectious agent in a biological sample employs a reagent which detects the presence of a specific infectious agent in the sample, and emits a detectable signal when the reagent reacts with the sample and detects the presence of the infectious agent. A test cartridge has a reaction chamber for receiving the sample and the reagent. The reaction chamber has a predetermined internal geometry and at least one inner surface. Introducing the sample and the reagent into the test cartridge mixes the sample and the reagent. A testing unit receives the test cartridge, and includes a sensor for detecting an emitted detectable signal. The detection of the emitted detectable signal is indicative of the presence of the infectious agent in the sample.

Abstract translation: 用于实时检测生物样品中感染因子的存在的便携式系统使用检测样品中特定感染因子的存在的试剂，并且当试剂与样品反应并发现存在时发出可检测信号 的感染因子。 测试盒具有用于接收样品和试剂的反应室。 反应室具有预定的内部几何形状和至少一个内表面。 将样品和试剂引入测试盒混合样品和试剂。 测试单元接收测试盒，并且包括用于检测发射的可检测信号的传感器。 发射的可检测信号的检测指示样品中感染因子的存在。