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    Polyethylene cross-linked with an anthocyanin
    2.
    发明授权
    Polyethylene cross-linked with an anthocyanin 有权
    聚乙烯与花青素交联

    公开(公告)号：US08439975B2

    公开(公告)日：2013-05-14

    申请号：US13623254

    申请日：2012-09-20

    Applicant: Howmedica Osteonics Corp.

    Inventor： Shulin He ,  Shi-Shen Yau ,  Aiguo Wang ,  Daniel E. Lawrynowicz

    IPC: A61F2/02

    CPC classification number: A61L2/14 ,  A61L2/08 ,  A61L2/20 ,  A61L27/16 ,  A61L27/505 ,  C08F10/02 ,  C08J3/28 ,  C08L53/00 ,  C08L2666/02 ,  C08L23/06

    Abstract: A method for manufacturing of ultrahigh molecular weight polyethylene (UHMWPE) for implants, where the implants have been machined out of UHMWPE blocks or extruded rods, has anthocyanin dispersely imbedded in the polyethylene. The implant is then exposed to γ ray or electron beam irradiation in an amount of at least 2.5 Mrad followed by a heat treatment to prevent the implant from becoming brittle in the long term as well as to improve strength and wear. The method includes mixing a powder or granulate resin of UHMWPE with an aqueous liquid that contains anthocyanin in a predetermined amount. The water is then evaporated to deposit the anthocyanin in a predetermined concentration on the polyethylene particles. The doped UHMWPE particles are compressed into blocks at temperatures in a range of approximately 135° C.-250° C. and pressures in a range of approximately 2-70 MPa. Medical implants are made from the blocks.

    Abstract translation: 用于植入物的超高分子量聚乙烯（UHMWPE）的制造方法，其中植入物已经由UHMWPE块或挤出棒加工而成，其中花青素分散嵌入聚乙烯中。 然后将植入物以至少2.5Mrad的量暴露于γ射线或电子束照射，然后进行热处理，以防止植入物在长期内变脆，并且改善强度和磨损。 该方法包括将UHMWPE的粉末或颗粒状树脂与含有预定量的花青素的含水液体混合。 然后将水蒸发以将预定浓度的花色苷沉积在聚乙烯颗粒上。 掺杂的UHMWPE颗粒在约135℃-250℃的温度和约2-70MPa范围内的压力下被压缩成块。 医疗植入物由块体制成。

    ANNEALING METHOD FOR CROSS-LINKED POLYETHYLENE
    9.
    发明申请
    ANNEALING METHOD FOR CROSS-LINKED POLYETHYLENE 审中-公开
    交联聚乙烯的退火方法

    公开(公告)号：US20150266210A1

    公开(公告)日：2015-09-24

    申请号：US14221995

    申请日：2014-03-21

    Applicant: Howmedica Osteonics Corp.

    Inventor： Lin Song ,  Daniel E. Lawrynowicz ,  Kim-phuong Nguyen Le ,  Kevor Shane Tenhuisen

    IPC: B29B13/08 ,  A61L27/16 ,  B29B13/04 ,  B29B15/00 ,  B29B11/14 ,  B29B13/02

    CPC classification number: B29B13/08 ,  A61L27/16 ,  B29B11/14 ,  B29B13/02 ,  B29B13/04 ,  B29B15/00 ,  B29C35/08 ,  B29C43/003 ,  B29C43/10 ,  B29C71/04 ,  B29C2035/0844 ,  B29C2035/085 ,  B29C2035/0877 ,  B29C2071/022 ,  B29K2023/0683 ,  B29K2105/253

    Abstract: A method for making an ultra-high weight polyethylene (UHMWPE) medical implant starts with obtaining a preform consolidated from UHMWPE resin. Thereafter the preform is hot isostaticly pressed at a temperature between 150° C. and 190° C. at a pressure up to 30,000 psi. After the hot isostatic pressing the preform is sequentially irradiated in a solid state at a total radiation dose of 2 to 10 MRad. The irradiated UHMWPE preform is then heated to a temperature of about 110° C. to about 190° C. for between 2 to 10 hours. The irradiated and heated preform is then cooled after each irradiation and heating to at or below 50° C., and thereafter a medical implant is formed from the preform. Alternately, the process can be performed on the medical implant itself.

    Abstract translation: 用于制造超高分子量聚乙烯（UHMWPE）医用植入物的方法首先获得由UHMWPE树脂固结的预制件。 此后，在高达30,000psi的压力下，将预制件在150℃至190℃之间的温度下进行热等静压。 在热等静压之后，以2〜10Mrad的总辐射剂量，以固态依次照射预成型体。 然后将照射的UHMWPE预制件加热至约110℃至约190℃的温度2至10小时。 然后将辐射和加热的预制件在每次照射之后冷却并加热到等于或低于50℃，然后从预成型件形成医用植入物。 或者，该过程可以在医疗植入物本身上进行。

    FEMORAL PROSTHESIS HEAD
    10.
    发明申请
    FEMORAL PROSTHESIS HEAD 有权
    股骨头假体

    公开(公告)号：US20140222158A1

    公开(公告)日：2014-08-07

    申请号：US13760449

    申请日：2013-02-06

    Applicant: Howmedica Osteonics Corp.

    Inventor： Daniel E. Lawrynowicz ,  Haitong Zeng ,  Zongtao Zhang ,  Aiguo Wang ,  Keenan Michael Hanson

    IPC: A61F2/36

    CPC classification number: A61F2/3609 ,  A61F2/30767 ,  A61F2002/30051 ,  A61F2002/30107 ,  A61F2002/30332 ,  A61F2002/30973 ,  A61F2002/3611

    Abstract: A prosthetic head for a femoral component has a metal shell with a tapered cavity. The shell has a part-spherical outer surface defining an inner portion terminating in an open end. A polymeric material completely fills the inner portion of the hollow shell extending from an inner surface of the shell to the open end. The polymeric material includes a conically tapered socket centered about the polar axis intermediate ends of the open end wherein the shell is a hollow titanium shell having an inner surface with a porous structure for receiving a portion of the polymeric material. The hollow titanium shell inner surface has at least one rib extending inwardly toward the conically tapered socket.

    Abstract translation: 用于股骨部件的假体头具有具有锥形腔的金属壳。 壳体具有限定终止于开口端的内部部分的球形外表面。 聚合物材料完全填充从壳体的内表面延伸到开口端的中空壳体的内部。 聚合物材料包括以开口端的极轴中心端为中心的圆锥形插座，其中壳体是中空钛壳体，其具有用于容纳聚合物材料的一部分的多孔结构的内表面。 中空的钛壳内表面具有至少一个朝着锥形锥形插座向内延伸的肋。

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