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    RAPID BLOOD TESTING SYSTEM
    1.
    发明申请
    RAPID BLOOD TESTING SYSTEM 有权

    公开(公告)号：US20220266242A1

    公开(公告)日：2022-08-25

    申请号：US17744283

    申请日：2022-05-13

    Applicant: InViDx Corp.

    Inventor： James Samsoondar

    IPC: B01L3/00 ,  G01N35/10 ,  G01N33/49 ,  G01N27/416

    Abstract: A point-of-care testing (POCT) system comprising an analyzer, a measurement cartridge, and a calibration cartridge for calibrating the measurement cartridge is described. The measurement cartridge comprises at least one electrochemical sensor for measuring the one or more properties of the blood sample, and the calibration cartridge comprises a similar at least one electrochemical sensor and at least one sealed blister containing calibration fluid for calibrating the measurement cartridge. Examples of properties of the blood sample may be pH, blood gases, electrolytes, and metabolites like glucose and creatinine. The measurement cartridge may also comprise an optical chamber for measuring for example, bilirubin and hemoglobin species, for which the analyzer comprises stored calibration algorithms. The optical chamber may be disposed in any location in the measurement cartridge, for receiving a portion of the blood sample.

    Joint hematology and biochemistry point-of-care testing system
    2.
    发明授权
    Joint hematology and biochemistry point-of-care testing system 有权

    公开(公告)号：US11327084B2

    公开(公告)日：2022-05-10

    申请号：US16575645

    申请日：2019-09-19

    Applicant: INVIDX CORP.

    Inventor： James Samsoondar

    IPC: G01N33/80 ,  G01N33/569 ,  G01N33/555 ,  G01N33/49

    Abstract: A joint point-of-care testing (POCT) analyzer, and a system comprising an analyzer and a cartridge, for measuring one or more analyte quantities per unit volume of blood and one or more formed element quantities per unit volume of blood, is described. Examples of formed elements of blood are red blood cells and white blood cells, and cell counts are determined by imaging using a two-dimensional multi-channel detector. Examples of analytes are hemoglobin and bilirubin, and hemoglobin and bilirubin concentrations are determined by spectroscopy using a one-dimensional multi-channel detector. Other examples of analytes are electrolytes, and electrolyte concentrations may be determined using biosensors incorporated in the cartridges.

    RAPID BLOOD TESTING SYSTEM
    3.
    发明申请
    RAPID BLOOD TESTING SYSTEM 有权

    公开(公告)号：US20250073706A1

    公开(公告)日：2025-03-06

    申请号：US18951992

    申请日：2024-11-19

    Applicant: InViDx Corp.

    Inventor： James Samsoondar

    IPC: B01L3/00 ,  G01N27/416 ,  G01N33/49 ,  G01N35/10

    Abstract: A point-of-care testing (POCT) system comprising an analyzer, a measurement cartridge, and a calibration cartridge for calibrating the measurement cartridge is described. The measurement cartridge comprises at least one electrochemical sensor for measuring the one or more properties of the blood sample, and the calibration cartridge comprises a similar at least one electrochemical sensor and at least one sealed blister containing calibration fluid for calibrating the measurement cartridge. Examples of properties of the blood sample may be pH, blood gases, electrolytes, and metabolites like glucose and creatinine. The measurement cartridge may also comprise an optical chamber for measuring for example, bilirubin and hemoglobin species, for which the analyzer comprises stored calibration algorithms. The optical chamber may be disposed in any location in the measurement cartridge, for receiving a portion of the blood sample.

    POINT-OF-CARE TESTING SYSTEM, ANALYZER AND METHOD
    4.
    发明公开
    POINT-OF-CARE TESTING SYSTEM, ANALYZER AND METHOD 审中-公开

    公开(公告)号：US20240060957A1

    公开(公告)日：2024-02-22

    申请号：US18206356

    申请日：2023-06-06

    Applicant: InViDx Corp.

    Inventor： James Samsoondar ,  Michael Licht

    IPC: G01N33/49 ,  G01N21/33 ,  G01N21/25 ,  B01L3/00

    CPC classification number: G01N33/492 ,  G01N21/33 ,  G01N21/255 ,  B01L3/502715 ,  G01N2201/08 ,  G01N2201/062 ,  B01L2200/16 ,  B01L2200/04 ,  B01L2300/0654

    Abstract: Described are various embodiments of a point-of-care testing (POCT) system, analyzer and method for measuring quantities of at least two analytes in a blood sample, for example bilirubin and hemoglobin. The system comprises an analyzer and a removable cartridge. The removable cartridge comprises an optical chamber configured for receiving the blood sample. The analyzer comprises a receptor for receiving the removable cartridge, a first and second set of incident electromagnetic radiation (EMR) for example two broadband LEDs, an EMR dispersive element for example a reflective grating, a photo diode array detector, and a processor. The two EMR sources are implemented in such a way so that the spectral wavelength range of EMR emerging from the blood is expanded, and the effect of stray EMR is mitigated. The expanded wavelength range and the mitigation of stray EMR allows the analyzer to measure quantities of the analytes in lysed or unlysed blood.

    Point-of-care testing cartridge with sliding cap
    5.
    发明授权
    Point-of-care testing cartridge with sliding cap 有权

    公开(公告)号：US11161109B2

    公开(公告)日：2021-11-02

    申请号：US16854201

    申请日：2020-04-21

    Applicant: INVIDX CORP.

    Inventor： James Samsoondar

    IPC: B01L3/00 ,  G01N35/00

    Abstract: A joint point-of-care testing (POCT) analyzer, and a system comprising an analyzer and a cartridge, for measuring one or more analyte quantities per unit volume of blood and one or more formed element quantities per unit volume of blood, is described. Examples of formed elements of blood are red blood cells and white blood cells, and cell counts are determined by imaging using a two-dimensional multi-channel detector. Examples of analytes are hemoglobin and bilirubin, and hemoglobin and bilirubin concentrations are determined by spectroscopy using a one-dimensional multi-channel detector. Other examples of analytes are electrolytes, and electrolyte concentrations may be determined using biosensors incorporated in the cartridges.

    Disposable cartridge system for point-of-care testing
    6.
    发明授权
    Disposable cartridge system for point-of-care testing 有权

    公开(公告)号：US10661270B2

    公开(公告)日：2020-05-26

    申请号：US16296539

    申请日：2019-03-08

    Applicant: INVIDX CORP.

    Inventor： James Samsoondar

    IPC: B01L3/00 ,  G01N33/49

    Abstract: Disposable cartridges comprising hinged caps and optical chambers for measuring one or more properties of a blood sample are described. Blood flow in the disposable cartridges may be regulated by either positive or negative pressure. Other embodiments of cartridges comprising a biosensor chamber disposed downstream of the optical chamber are also described. Methods for measuring one or more properties of a blood sample using different cartridge embodiments are provided.

    Disposable cartridge with hinged cap
    7.
    发明授权
    Disposable cartridge with hinged cap 有权

    公开(公告)号：US10272430B2

    公开(公告)日：2019-04-30

    申请号：US15995895

    申请日：2018-06-01

    Applicant: INVIDX CORP.

    Inventor： James Samsoondar

    IPC: B01L3/00 ,  G01N33/86

    Abstract: A disposable cartridge and method for measuring one or more properties of a blood sample are provided. The disposable cartridge can receive a sample when it is in an unsealed configuration. After adjusting the cartridge from the unsealed configuration to a sealed configuration, facilitated by a hingedly attached cap, pressurized air from an air bladder may be used to force the blood from a sample storage well into a detection chamber in a regulated manner, so that the one or more properties of the blood sample may then be measured.

    Point-of-care testing system, analyzer and method
    9.
    发明授权
    Point-of-care testing system, analyzer and method 有权

    公开(公告)号：US12000824B2

    公开(公告)日：2024-06-04

    申请号：US18206356

    申请日：2023-06-06

    Applicant: InViDx Corp.

    Inventor： James Samsoondar ,  Michael Licht

    IPC: G01N33/48 ,  B01L3/00 ,  G01N21/25 ,  G01N21/33 ,  G01N33/49

    CPC classification number: G01N33/492 ,  B01L3/502715 ,  G01N21/255 ,  G01N21/33 ,  B01L2200/04 ,  B01L2200/16 ,  B01L2300/0654 ,  G01N2201/062 ,  G01N2201/08

    Abstract: Described are various embodiments of a point-of-care testing (POCT) system, analyzer and method for measuring quantities of at least two analytes in a blood sample, for example bilirubin and hemoglobin. The system comprises an analyzer and a removable cartridge. The removable cartridge comprises an optical chamber configured for receiving the blood sample. The analyzer comprises a receptor for receiving the removable cartridge, a first and second set of incident electromagnetic radiation (EMR) for example two broadband LEDs, an EMR dispersive element for example a reflective grating, a photo diode array detector, and a processor. The two EMR sources are implemented in such a way so that the spectral wavelength range of EMR emerging from the blood is expanded, and the effect of stray EMR is mitigated. The expanded wavelength range and the mitigation of stray EMR allows the analyzer to measure quantities of the analytes in lysed or unlysed blood.

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